JP2016529269A5 - - Google Patents
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- Publication number
- JP2016529269A5 JP2016529269A5 JP2016537292A JP2016537292A JP2016529269A5 JP 2016529269 A5 JP2016529269 A5 JP 2016529269A5 JP 2016537292 A JP2016537292 A JP 2016537292A JP 2016537292 A JP2016537292 A JP 2016537292A JP 2016529269 A5 JP2016529269 A5 JP 2016529269A5
- Authority
- JP
- Japan
- Prior art keywords
- acid derivative
- sialic acid
- group
- formula
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical class CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 claims 17
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 239000002253 acid Substances 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- 239000007983 Tris buffer Substances 0.000 claims 6
- 150000001412 amines Chemical class 0.000 claims 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 5
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 5
- 241000700605 Viruses Species 0.000 claims 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000012453 solvate Substances 0.000 claims 2
- 206010001257 Adenoviral conjunctivitis Diseases 0.000 claims 1
- 208000001860 Eye Infections Diseases 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 208000021373 epidemic keratoconjunctivitis Diseases 0.000 claims 1
- 239000012458 free base Substances 0.000 claims 1
- 239000000644 isotonic solution Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 201000006476 shipyard eye Diseases 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1350991-4 | 2013-08-28 | ||
| SE1350991 | 2013-08-28 | ||
| PCT/EP2014/068252 WO2015028548A1 (en) | 2013-08-28 | 2014-08-28 | Multivalent sialic acid derivates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016529269A JP2016529269A (ja) | 2016-09-23 |
| JP2016529269A5 true JP2016529269A5 (enExample) | 2017-09-07 |
| JP6360895B2 JP6360895B2 (ja) | 2018-07-18 |
Family
ID=51454687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537292A Expired - Fee Related JP6360895B2 (ja) | 2013-08-28 | 2014-08-28 | 多価シアル酸誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10011628B2 (enExample) |
| EP (1) | EP3039029B1 (enExample) |
| JP (1) | JP6360895B2 (enExample) |
| KR (1) | KR20160073372A (enExample) |
| CN (1) | CN105722849B (enExample) |
| AU (1) | AU2014314212B2 (enExample) |
| CA (1) | CA2921634A1 (enExample) |
| ES (1) | ES2677219T3 (enExample) |
| IL (1) | IL244246B (enExample) |
| MX (1) | MX2016002578A (enExample) |
| PL (1) | PL3039029T3 (enExample) |
| TR (1) | TR201809630T4 (enExample) |
| WO (1) | WO2015028548A1 (enExample) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9904289D0 (sv) | 1999-11-26 | 1999-11-26 | Niklas Arnberg | Method and camposition for the treatment of adenovairal ocular infections |
| US20070020620A1 (en) * | 2005-07-14 | 2007-01-25 | Finn M G | Compositions and methods for coupling a plurality of compounds to a scaffold |
| US20080194801A1 (en) * | 2007-02-14 | 2008-08-14 | Swanson Basil I | Robust multidentate ligands for diagnosis and anti-viral drugs for influenza and related viruses |
| BR112012000381A2 (pt) | 2009-07-07 | 2016-03-29 | Adenovir Pharma Ab | novos compostos antivirais úteis para o tratamento ou prevenção de queratoconjuntivite epidêmica |
| KR101217685B1 (ko) | 2010-05-28 | 2013-01-02 | 서강대학교산학협력단 | 서로 다른 실릴기로 보호된 알킨 그룹을 갖는 삼중연결고리 화합물, 이의 제조방법 및 응용 |
| WO2011158068A1 (en) | 2010-06-18 | 2011-12-22 | Centre National De La Recherche Scientifique (Cnrs) | Non covalent molecular structure, device comprising the same and its use for detection of lectin |
-
2014
- 2014-08-28 KR KR1020167007981A patent/KR20160073372A/ko not_active Ceased
- 2014-08-28 WO PCT/EP2014/068252 patent/WO2015028548A1/en not_active Ceased
- 2014-08-28 JP JP2016537292A patent/JP6360895B2/ja not_active Expired - Fee Related
- 2014-08-28 EP EP14758353.8A patent/EP3039029B1/en not_active Not-in-force
- 2014-08-28 MX MX2016002578A patent/MX2016002578A/es unknown
- 2014-08-28 CN CN201480047068.3A patent/CN105722849B/zh not_active Expired - Fee Related
- 2014-08-28 CA CA2921634A patent/CA2921634A1/en not_active Abandoned
- 2014-08-28 TR TR2018/09630T patent/TR201809630T4/tr unknown
- 2014-08-28 AU AU2014314212A patent/AU2014314212B2/en not_active Ceased
- 2014-08-28 US US14/914,988 patent/US10011628B2/en not_active Expired - Fee Related
- 2014-08-28 PL PL14758353T patent/PL3039029T3/pl unknown
- 2014-08-28 ES ES14758353.8T patent/ES2677219T3/es active Active
-
2016
- 2016-02-23 IL IL244246A patent/IL244246B/en not_active IP Right Cessation
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