MX2016002578A - Derivados multivalentes de acido sialico. - Google Patents

Derivados multivalentes de acido sialico.

Info

Publication number
MX2016002578A
MX2016002578A MX2016002578A MX2016002578A MX2016002578A MX 2016002578 A MX2016002578 A MX 2016002578A MX 2016002578 A MX2016002578 A MX 2016002578A MX 2016002578 A MX2016002578 A MX 2016002578A MX 2016002578 A MX2016002578 A MX 2016002578A
Authority
MX
Mexico
Prior art keywords
sialic acid
acid derivates
tri
multivalent sialic
multivalent
Prior art date
Application number
MX2016002578A
Other languages
English (en)
Inventor
Arnberg Niklas
Elofsson Mikael
CARABALLO Rémi
Original Assignee
Adenovir Pharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adenovir Pharma Ab filed Critical Adenovir Pharma Ab
Publication of MX2016002578A publication Critical patent/MX2016002578A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se describen derivados de ácido siálico trivalentes o tetravalentes que comprenden una porción de núcleo a la cual están conectados 3 o 4 residuos de ácido siálico por medio de un enlazante. Dichos derivados inhiben la unión de adenovirus a células humanas, con lo cual se pueden tratar o prevenir infecciones tales como queratoconjuntivitis epidémica mediante la administración de los derivados de ácido siálico trivalentes o tetravalentes.
MX2016002578A 2013-08-28 2014-08-28 Derivados multivalentes de acido sialico. MX2016002578A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1350991 2013-08-28
PCT/EP2014/068252 WO2015028548A1 (en) 2013-08-28 2014-08-28 Multivalent sialic acid derivates

Publications (1)

Publication Number Publication Date
MX2016002578A true MX2016002578A (es) 2016-09-08

Family

ID=51454687

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016002578A MX2016002578A (es) 2013-08-28 2014-08-28 Derivados multivalentes de acido sialico.

Country Status (13)

Country Link
US (1) US10011628B2 (es)
EP (1) EP3039029B1 (es)
JP (1) JP6360895B2 (es)
KR (1) KR20160073372A (es)
CN (1) CN105722849B (es)
AU (1) AU2014314212B2 (es)
CA (1) CA2921634A1 (es)
ES (1) ES2677219T3 (es)
IL (1) IL244246B (es)
MX (1) MX2016002578A (es)
PL (1) PL3039029T3 (es)
TR (1) TR201809630T4 (es)
WO (1) WO2015028548A1 (es)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904289D0 (sv) 1999-11-26 1999-11-26 Niklas Arnberg Method and camposition for the treatment of adenovairal ocular infections
US20070020620A1 (en) * 2005-07-14 2007-01-25 Finn M G Compositions and methods for coupling a plurality of compounds to a scaffold
US20080194801A1 (en) * 2007-02-14 2008-08-14 Swanson Basil I Robust multidentate ligands for diagnosis and anti-viral drugs for influenza and related viruses
ES2434791T3 (es) 2009-07-07 2013-12-17 Adenovir Pharma Ab Nuevos compuestos antivirales útiles para el tratamiento o la prevención de queratoconjuntivitis epidémica
KR101217685B1 (ko) 2010-05-28 2013-01-02 서강대학교산학협력단 서로 다른 실릴기로 보호된 알킨 그룹을 갖는 삼중연결고리 화합물, 이의 제조방법 및 응용
WO2011158068A1 (en) 2010-06-18 2011-12-22 Centre National De La Recherche Scientifique (Cnrs) Non covalent molecular structure, device comprising the same and its use for detection of lectin

Also Published As

Publication number Publication date
ES2677219T3 (es) 2018-07-31
EP3039029B1 (en) 2018-04-11
AU2014314212B2 (en) 2018-03-01
CN105722849B (zh) 2019-01-29
JP2016529269A (ja) 2016-09-23
WO2015028548A1 (en) 2015-03-05
CN105722849A (zh) 2016-06-29
US20160207955A1 (en) 2016-07-21
EP3039029A1 (en) 2016-07-06
US10011628B2 (en) 2018-07-03
IL244246A0 (en) 2016-04-21
PL3039029T3 (pl) 2018-10-31
AU2014314212A1 (en) 2016-03-10
JP6360895B2 (ja) 2018-07-18
TR201809630T4 (tr) 2018-07-23
IL244246B (en) 2019-02-28
KR20160073372A (ko) 2016-06-24
CA2921634A1 (en) 2015-03-05

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