AU2014314212B2 - Multivalent sialic acid derivates - Google Patents

Multivalent sialic acid derivates Download PDF

Info

Publication number
AU2014314212B2
AU2014314212B2 AU2014314212A AU2014314212A AU2014314212B2 AU 2014314212 B2 AU2014314212 B2 AU 2014314212B2 AU 2014314212 A AU2014314212 A AU 2014314212A AU 2014314212 A AU2014314212 A AU 2014314212A AU 2014314212 B2 AU2014314212 B2 AU 2014314212B2
Authority
AU
Australia
Prior art keywords
sialic acid
groups
formula
hadv
acid derivate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2014314212A
Other languages
English (en)
Other versions
AU2014314212A1 (en
Inventor
Niklas Arnberg
Remi Caraballo
Mikael Elofsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adenovir Pharma AB
Original Assignee
Adenovir Pharma AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adenovir Pharma AB filed Critical Adenovir Pharma AB
Publication of AU2014314212A1 publication Critical patent/AU2014314212A1/en
Application granted granted Critical
Publication of AU2014314212B2 publication Critical patent/AU2014314212B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU2014314212A 2013-08-28 2014-08-28 Multivalent sialic acid derivates Ceased AU2014314212B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1350991-4 2013-08-28
SE1350991 2013-08-28
PCT/EP2014/068252 WO2015028548A1 (en) 2013-08-28 2014-08-28 Multivalent sialic acid derivates

Publications (2)

Publication Number Publication Date
AU2014314212A1 AU2014314212A1 (en) 2016-03-10
AU2014314212B2 true AU2014314212B2 (en) 2018-03-01

Family

ID=51454687

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014314212A Ceased AU2014314212B2 (en) 2013-08-28 2014-08-28 Multivalent sialic acid derivates

Country Status (13)

Country Link
US (1) US10011628B2 (enExample)
EP (1) EP3039029B1 (enExample)
JP (1) JP6360895B2 (enExample)
KR (1) KR20160073372A (enExample)
CN (1) CN105722849B (enExample)
AU (1) AU2014314212B2 (enExample)
CA (1) CA2921634A1 (enExample)
ES (1) ES2677219T3 (enExample)
IL (1) IL244246B (enExample)
MX (1) MX2016002578A (enExample)
PL (1) PL3039029T3 (enExample)
TR (1) TR201809630T4 (enExample)
WO (1) WO2015028548A1 (enExample)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904289D0 (sv) 1999-11-26 1999-11-26 Niklas Arnberg Method and camposition for the treatment of adenovairal ocular infections
US20070020620A1 (en) * 2005-07-14 2007-01-25 Finn M G Compositions and methods for coupling a plurality of compounds to a scaffold
US20080194801A1 (en) * 2007-02-14 2008-08-14 Swanson Basil I Robust multidentate ligands for diagnosis and anti-viral drugs for influenza and related viruses
BR112012000381A2 (pt) 2009-07-07 2016-03-29 Adenovir Pharma Ab novos compostos antivirais úteis para o tratamento ou prevenção de queratoconjuntivite epidêmica
KR101217685B1 (ko) 2010-05-28 2013-01-02 서강대학교산학협력단 서로 다른 실릴기로 보호된 알킨 그룹을 갖는 삼중연결고리 화합물, 이의 제조방법 및 응용
WO2011158068A1 (en) 2010-06-18 2011-12-22 Centre National De La Recherche Scientifique (Cnrs) Non covalent molecular structure, device comprising the same and its use for detection of lectin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOHANSSON ET AL, "Multivalent HSA Conjugates of 3'-Sialyllactose are Potent Inhibitors of Adenoviral Cell Attachment and Infection", CHEMBIOCHEM - A EUROPEAN JOURNAL OF CHEMICAL BIOLOGY, pages 358 - 364 *

Also Published As

Publication number Publication date
IL244246B (en) 2019-02-28
CA2921634A1 (en) 2015-03-05
KR20160073372A (ko) 2016-06-24
EP3039029B1 (en) 2018-04-11
CN105722849B (zh) 2019-01-29
ES2677219T3 (es) 2018-07-31
IL244246A0 (en) 2016-04-21
CN105722849A (zh) 2016-06-29
WO2015028548A1 (en) 2015-03-05
US10011628B2 (en) 2018-07-03
EP3039029A1 (en) 2016-07-06
MX2016002578A (es) 2016-09-08
US20160207955A1 (en) 2016-07-21
AU2014314212A1 (en) 2016-03-10
PL3039029T3 (pl) 2018-10-31
JP6360895B2 (ja) 2018-07-18
JP2016529269A (ja) 2016-09-23
TR201809630T4 (tr) 2018-07-23

Similar Documents

Publication Publication Date Title
ES2512501T3 (es) Nuevos inhibidores de galectinas a base de 3-triazolil-galactósido
CN108884121B (zh) 新组合物和治疗方法
KR101156273B1 (ko) 황산화 올리고사카라이드 유도체
CN108350014B (zh) 氨基糖苷衍生物及其在治疗遗传性病症中的应用
WO2008029278A2 (en) Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins
US20120202877A1 (en) Anti-influenza agents
US20110112184A1 (en) Compounds with glycidic structure active in the therapy of systemic and local inflammation
EP3039029B1 (en) Multivalent sialic acid derivates
EP1664072A1 (en) Novel sulfenamides
RU2565593C2 (ru) Новые противовирусные соединения, подходящие для лечения или предотвращения эпидемического кератоконъюнктивата
WO2013152848A1 (en) Glycomimetics as pseudomonas aeruginosa lectin inhibitors
EP3981777A1 (en) Antiviral compounds and polymers
AU2004266177A1 (en) Novel sulfenamides
AU2003246615A1 (en) An antimicrobial agent
HK1108581A (en) Sulfated oligosaccharide derivatives
HK1197915A (en) Sulfated oligosaccharide derivatives
HK1197915B (en) Sulfated oligosaccharide derivatives

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired