JP2016528236A5 - - Google Patents
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- Publication number
- JP2016528236A5 JP2016528236A5 JP2016533450A JP2016533450A JP2016528236A5 JP 2016528236 A5 JP2016528236 A5 JP 2016528236A5 JP 2016533450 A JP2016533450 A JP 2016533450A JP 2016533450 A JP2016533450 A JP 2016533450A JP 2016528236 A5 JP2016528236 A5 JP 2016528236A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- monoclonal antibody
- human
- timp2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361863073P | 2013-08-07 | 2013-08-07 | |
| US61/863,073 | 2013-08-07 | ||
| PCT/US2014/050195 WO2015021308A1 (en) | 2013-08-07 | 2014-08-07 | Assays for timp2 having improved performance in biological samples |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016528236A JP2016528236A (ja) | 2016-09-15 |
| JP2016528236A5 true JP2016528236A5 (https=) | 2017-08-10 |
Family
ID=52461941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533450A Pending JP2016528236A (ja) | 2013-08-07 | 2014-08-07 | 生物学的試料において改善された性能を有するｔｉｍｐ２のためのアッセイ |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9879091B2 (https=) |
| EP (2) | EP3617234A1 (https=) |
| JP (1) | JP2016528236A (https=) |
| KR (1) | KR20160039682A (https=) |
| CN (1) | CN105531291A (https=) |
| AU (1) | AU2014305883A1 (https=) |
| BR (1) | BR112016002685A2 (https=) |
| CA (1) | CA2920521A1 (https=) |
| EA (1) | EA201690185A1 (https=) |
| HK (1) | HK1222180A1 (https=) |
| MX (1) | MX2016001573A (https=) |
| WO (1) | WO2015021308A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ607703A (en) | 2008-10-21 | 2014-09-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP5763098B2 (ja) | 2009-12-20 | 2015-08-12 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| ES2734494T3 (es) | 2011-12-08 | 2019-12-10 | Astute Medical Inc | Métodos y usos para el diagnóstico de una lesión renal y de una insuficiencia renal |
| TR201807542T4 (tr) | 2013-01-17 | 2018-06-21 | Astute Medical Inc | Böbrek hasarı ve böbrek yetmezliği teşhisi ve prognozuna yönelik metotlar ve bileşimler. |
| US10300108B2 (en) | 2013-12-03 | 2019-05-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US11243202B2 (en) | 2015-04-09 | 2022-02-08 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN108700609A (zh) * | 2015-12-30 | 2018-10-23 | 生物辐射实验室股份有限公司 | 具有自动校准的液滴测定系统 |
| EP3465201A4 (en) | 2016-06-06 | 2020-08-26 | Astute Medical, Inc. | MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR |
| WO2018006049A1 (en) * | 2016-06-30 | 2018-01-04 | The Research Foundation For The State University Of New York | Compositions and methods for modifying activity of extracellular mmp-2 |
| CN110352073A (zh) * | 2016-10-28 | 2019-10-18 | 机敏医药股份有限公司 | 针对timp-2的抗体用于改善肾功能的用途 |
| US11346846B2 (en) | 2017-02-06 | 2022-05-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US11718682B2 (en) | 2017-04-05 | 2023-08-08 | Astute Medical, Inc. | Assays for TIMP2 having improved performance in biological samples |
| KR20210019459A (ko) | 2018-05-24 | 2021-02-22 | 레니버스 테라퓨틱스, 인크. | 신장 손상 및 신부전 위험이 있는 환자를 치료하는 방법 |
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| US459004A (en) | 1891-09-08 | Box for steaming cops | ||
| DE3029579C2 (de) | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5698671A (en) * | 1989-03-21 | 1997-12-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Metalloproteinase peptides |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
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| WO1996033735A1 (en) | 1995-04-27 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
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| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| CA2072758A1 (en) | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| CA2107894C (en) | 1991-04-10 | 2003-10-14 | Kenneth F. Buechler | Crosstalk inhibitors and their uses |
| EP0579767B1 (en) | 1991-04-11 | 2000-08-23 | Biosite Diagnostics Inc. | Novel conjugates and assays for simultaneous detection of multiple ligands |
| US6797492B2 (en) | 1991-05-17 | 2004-09-28 | Merck & Co., Inc. | Method for reducing the immunogenicity of antibody variable domains |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
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| US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
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| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
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| CA2722378C (en) | 1996-12-03 | 2015-02-03 | Amgen Fremont Inc. | Human antibodies that bind tnf.alpha. |
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| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
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| WO1999047930A1 (en) * | 1998-03-16 | 1999-09-23 | Quidel Corporation | Immunoassay device and method |
| US7214542B2 (en) * | 2003-01-30 | 2007-05-08 | Michael Hutchinson | Method of processing assay test results |
| WO2004096832A2 (en) * | 2003-04-29 | 2004-11-11 | Children's Medical Center Corporation | Novel antiangiogenic peptides |
| US20070031286A1 (en) * | 2003-08-11 | 2007-02-08 | Kyowa Medex Co., Ltd. | Tool for measuring object to be measured, measuring device, and measuring method |
| WO2006010529A1 (en) * | 2004-07-28 | 2006-02-02 | F. Hoffmann-La Roche Ag | Timp-2 as target/marker of beta cell failure |
| US7485468B2 (en) * | 2004-10-15 | 2009-02-03 | Galapagos Bv | Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases |
| WO2007048102A2 (en) * | 2005-10-18 | 2007-04-26 | The Government Of The United States, As Represented By The Secretary Of Health And Human Services | Angio-inhibitory peptides derived from human timp-2 |
| NZ607703A (en) | 2008-10-21 | 2014-09-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US8900881B2 (en) * | 2008-12-30 | 2014-12-02 | Jin Po Lee | Quantitative analyte assay device and method |
| JP5763098B2 (ja) | 2009-12-20 | 2015-08-12 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| EP2554990B1 (en) * | 2010-03-31 | 2016-08-31 | Sekisui Medical Co., Ltd. | Measurement method using immunochromatography, test strip for immunochromatography, and measurement reagent kit for immunochromatography |
-
2014
- 2014-08-07 EP EP19183111.4A patent/EP3617234A1/en not_active Withdrawn
- 2014-08-07 AU AU2014305883A patent/AU2014305883A1/en not_active Abandoned
- 2014-08-07 EP EP14834090.4A patent/EP3030582A4/en not_active Withdrawn
- 2014-08-07 WO PCT/US2014/050195 patent/WO2015021308A1/en not_active Ceased
- 2014-08-07 CA CA2920521A patent/CA2920521A1/en not_active Abandoned
- 2014-08-07 JP JP2016533450A patent/JP2016528236A/ja active Pending
- 2014-08-07 EA EA201690185A patent/EA201690185A1/ru unknown
- 2014-08-07 BR BR112016002685A patent/BR112016002685A2/pt not_active Application Discontinuation
- 2014-08-07 HK HK16110255.1A patent/HK1222180A1/zh unknown
- 2014-08-07 KR KR1020167005705A patent/KR20160039682A/ko not_active Withdrawn
- 2014-08-07 MX MX2016001573A patent/MX2016001573A/es unknown
- 2014-08-07 US US14/910,661 patent/US9879091B2/en active Active
- 2014-08-07 CN CN201480048192.1A patent/CN105531291A/zh active Pending
-
2018
- 2018-01-29 US US15/882,936 patent/US10457744B2/en active Active
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