JP2016527223A5 - - Google Patents
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- Publication number
- JP2016527223A5 JP2016527223A5 JP2016526557A JP2016526557A JP2016527223A5 JP 2016527223 A5 JP2016527223 A5 JP 2016527223A5 JP 2016526557 A JP2016526557 A JP 2016526557A JP 2016526557 A JP2016526557 A JP 2016526557A JP 2016527223 A5 JP2016527223 A5 JP 2016527223A5
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- JP
- Japan
- Prior art keywords
- alkyl
- group
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- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- JUHJMRCPZRWQAM-TVVDDFTJSA-N CC(CO[C@@H]12)[C@H]1OCC2O Chemical compound CC(CO[C@@H]12)[C@H]1OCC2O JUHJMRCPZRWQAM-TVVDDFTJSA-N 0.000 description 1
- UODXCYZDMHPIJE-KYZUINATSA-N C[C@H](CC1)CC[C@@H]1C(C)(C)O Chemical compound C[C@H](CC1)CC[C@@H]1C(C)(C)O UODXCYZDMHPIJE-KYZUINATSA-N 0.000 description 1
- QTDXSEZXAPHVBI-LJGSYFOKSA-N C[C@H](CC1)CC[C@@H]1C(O)=O Chemical compound C[C@H](CC1)CC[C@@H]1C(O)=O QTDXSEZXAPHVBI-LJGSYFOKSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13176929 | 2013-07-17 | ||
| EP13176929.1 | 2013-07-17 | ||
| PCT/EP2014/065004 WO2015007669A1 (en) | 2013-07-17 | 2014-07-14 | New azabenzimidazole derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016527223A JP2016527223A (ja) | 2016-09-08 |
| JP2016527223A5 true JP2016527223A5 (https=) | 2017-07-20 |
| JP6491656B2 JP6491656B2 (ja) | 2019-03-27 |
Family
ID=48790302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016526557A Active JP6491656B2 (ja) | 2013-07-17 | 2014-07-14 | 新規アザベンズイミダゾール誘導体 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9492436B2 (https=) |
| EP (1) | EP3022210B1 (https=) |
| JP (1) | JP6491656B2 (https=) |
| KR (1) | KR20160033749A (https=) |
| CN (1) | CN105377857B (https=) |
| AR (1) | AR096936A1 (https=) |
| AU (1) | AU2014292236B2 (https=) |
| CA (1) | CA2918401A1 (https=) |
| CL (1) | CL2016000026A1 (https=) |
| DK (1) | DK3022210T3 (https=) |
| EA (1) | EA032195B1 (https=) |
| ES (1) | ES2669543T3 (https=) |
| HU (1) | HUE038261T2 (https=) |
| MX (1) | MX359040B (https=) |
| PH (1) | PH12016500092B1 (https=) |
| PL (1) | PL3022210T3 (https=) |
| TR (1) | TR201806860T4 (https=) |
| TW (1) | TW201546076A (https=) |
| UY (1) | UY35668A (https=) |
| WO (1) | WO2015007669A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016023789A1 (en) * | 2014-08-11 | 2016-02-18 | Boehringer Ingelheim International Gmbh | Azabenzimidazole derivatives as amp protein kinase agonistes |
| US9980948B2 (en) | 2014-08-27 | 2018-05-29 | Shionogi & Co., Ltd. | Azaindole derivative having AMPK-activating activity |
| MX2017005158A (es) | 2014-10-28 | 2017-07-27 | Shionogi & Co | Derivado heterociclico que tiene actividad de activacion de proteina cinasa activada por adenosina monofostato (ampk). |
| WO2016113299A1 (en) * | 2015-01-16 | 2016-07-21 | Boehringer Ingelheim International Gmbh | New azabenzimidazole derivatives |
| JPWO2017146186A1 (ja) | 2016-02-26 | 2018-12-20 | 塩野義製薬株式会社 | Ａｍｐｋ活性化作用を有する５−フェニルアザインドール誘導体 |
| CN109476661A (zh) * | 2016-05-20 | 2019-03-15 | 盐野义制药株式会社 | 具有ampk活化作用的5-取代苯并咪唑及5-取代氮杂苯并咪唑衍生物 |
| AU2019362747A1 (en) * | 2018-10-15 | 2021-06-03 | Gero Pte. Ltd. | PFKFB3 inhibitors and their uses |
| UY38941A (es) | 2019-11-11 | 2021-06-30 | Pi Industries Ltd | Nuevas sulfiliminas o sulfoximinas que contienen compuestos heterocíclicos fungicidas |
| WO2021236617A1 (en) | 2020-05-19 | 2021-11-25 | Kallyope, Inc. | Ampk activators |
| CA3183575A1 (en) | 2020-06-26 | 2021-12-30 | Iyassu Sebhat | Ampk activators |
| EP4211139A4 (en) | 2020-09-10 | 2024-12-18 | Gasherbrum Bio, Inc. | HETEROCYCLIC GLP-1 AGONISTS |
| AU2024222719A1 (en) | 2023-02-16 | 2025-08-21 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2043744A2 (en) * | 2006-07-13 | 2009-04-08 | SmithKline Beecham Corporation | Chemical compounds |
| WO2012033149A1 (ja) | 2010-09-10 | 2012-03-15 | 塩野義製薬株式会社 | Ａｍｐｋ活性化作用を有するヘテロ環縮合イミダゾール誘導体 |
| BR112013021236B1 (pt) * | 2011-02-25 | 2021-05-25 | Merck Sharp & Dohme Corp | composto derivado de benzimidazol, e, composição |
| WO2014031468A1 (en) * | 2012-08-22 | 2014-02-27 | Merck Sharp & Dohme Corp. | Novel benzimidazole hexahydrofuro[3,2-b]furan derivatives |
| RU2015109706A (ru) * | 2012-08-22 | 2016-10-10 | Мерк Шарп И Доум Корп. | Новые производные азабензимидазол гексагидрофуро[3, 2-в]фурана |
| WO2014069426A1 (ja) * | 2012-10-31 | 2014-05-08 | 塩野義製薬株式会社 | Ａｍｐｋ活性化作用を有するベンズイミダゾールおよびアザベンズイミダゾール誘導体 |
-
2014
- 2014-07-14 TR TR2018/06860T patent/TR201806860T4/tr unknown
- 2014-07-14 JP JP2016526557A patent/JP6491656B2/ja active Active
- 2014-07-14 AU AU2014292236A patent/AU2014292236B2/en not_active Ceased
- 2014-07-14 WO PCT/EP2014/065004 patent/WO2015007669A1/en not_active Ceased
- 2014-07-14 CA CA2918401A patent/CA2918401A1/en not_active Abandoned
- 2014-07-14 EP EP14738531.4A patent/EP3022210B1/en active Active
- 2014-07-14 HU HUE14738531A patent/HUE038261T2/hu unknown
- 2014-07-14 KR KR1020167004147A patent/KR20160033749A/ko not_active Withdrawn
- 2014-07-14 CN CN201480040799.5A patent/CN105377857B/zh active Active
- 2014-07-14 EA EA201600113A patent/EA032195B1/ru not_active IP Right Cessation
- 2014-07-14 MX MX2016000547A patent/MX359040B/es active IP Right Grant
- 2014-07-14 DK DK14738531.4T patent/DK3022210T3/en active
- 2014-07-14 PL PL14738531T patent/PL3022210T3/pl unknown
- 2014-07-14 ES ES14738531.4T patent/ES2669543T3/es active Active
- 2014-07-15 US US14/331,359 patent/US9492436B2/en active Active
- 2014-07-16 TW TW103124425A patent/TW201546076A/zh unknown
- 2014-07-16 AR ARP140102623A patent/AR096936A1/es unknown
- 2014-07-17 UY UY0001035668A patent/UY35668A/es unknown
-
2016
- 2016-01-07 CL CL2016000026A patent/CL2016000026A1/es unknown
- 2016-01-14 PH PH12016500092A patent/PH12016500092B1/en unknown
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