JP2016527223A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016527223A5 JP2016527223A5 JP2016526557A JP2016526557A JP2016527223A5 JP 2016527223 A5 JP2016527223 A5 JP 2016527223A5 JP 2016526557 A JP2016526557 A JP 2016526557A JP 2016526557 A JP2016526557 A JP 2016526557A JP 2016527223 A5 JP2016527223 A5 JP 2016527223A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- groups
- optionally
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JUHJMRCPZRWQAM-TVVDDFTJSA-N CC(CO[C@@H]12)[C@H]1OCC2O Chemical compound CC(CO[C@@H]12)[C@H]1OCC2O JUHJMRCPZRWQAM-TVVDDFTJSA-N 0.000 description 1
- UODXCYZDMHPIJE-KYZUINATSA-N C[C@H](CC1)CC[C@@H]1C(C)(C)O Chemical compound C[C@H](CC1)CC[C@@H]1C(C)(C)O UODXCYZDMHPIJE-KYZUINATSA-N 0.000 description 1
- QTDXSEZXAPHVBI-LJGSYFOKSA-N C[C@H](CC1)CC[C@@H]1C(O)=O Chemical compound C[C@H](CC1)CC[C@@H]1C(O)=O QTDXSEZXAPHVBI-LJGSYFOKSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13176929.1 | 2013-07-17 | ||
| EP13176929 | 2013-07-17 | ||
| PCT/EP2014/065004 WO2015007669A1 (en) | 2013-07-17 | 2014-07-14 | New azabenzimidazole derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016527223A JP2016527223A (ja) | 2016-09-08 |
| JP2016527223A5 true JP2016527223A5 (cg-RX-API-DMAC10.html) | 2017-07-20 |
| JP6491656B2 JP6491656B2 (ja) | 2019-03-27 |
Family
ID=48790302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016526557A Active JP6491656B2 (ja) | 2013-07-17 | 2014-07-14 | 新規アザベンズイミダゾール誘導体 |
Country Status (20)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3180338B1 (en) * | 2014-08-11 | 2018-05-09 | Boehringer Ingelheim International GmbH | Azabenzimidazole derivatives as amp protein kinase agonistes |
| CN107108605A (zh) | 2014-08-27 | 2017-08-29 | 盐野义制药株式会社 | 具有ampk活化作用的氮杂吲哚衍生物 |
| CN107108521A (zh) | 2014-10-28 | 2017-08-29 | 盐野义制药株式会社 | 具有ampk活化作用的杂环衍生物 |
| US10053471B2 (en) * | 2015-01-16 | 2018-08-21 | Boehringer Ingelheim International Gmbh | Azabenzimidazole derivatives |
| WO2017146186A1 (ja) | 2016-02-26 | 2017-08-31 | 塩野義製薬株式会社 | Ａｍｐｋ活性化作用を有する５－フェニルアザインドール誘導体 |
| EP3459949A4 (en) * | 2016-05-20 | 2020-04-08 | Shionogi & Co., Ltd | 5-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE AND 5-SUBSTITUTED AZABENZIMIDAZOLE DERIVATIVE WITH AMPK ACTIVATION EFFECT |
| JP2022508751A (ja) * | 2018-10-15 | 2022-01-19 | ゲロ ディスカバリー リミテッド ライアビリティ カンパニー | Ｐｆｋｆｂ３阻害剤とその使用 |
| UY38941A (es) | 2019-11-11 | 2021-06-30 | Pi Industries Ltd | Nuevas sulfiliminas o sulfoximinas que contienen compuestos heterocíclicos fungicidas |
| MX2022014505A (es) | 2020-05-19 | 2022-12-13 | Kallyope Inc | Activadores de la ampk. |
| CA3183575A1 (en) | 2020-06-26 | 2021-12-30 | Iyassu Sebhat | Ampk activators |
| WO2022052958A1 (en) | 2020-09-10 | 2022-03-17 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| KR20250168210A (ko) | 2023-02-16 | 2025-12-02 | 가셔브룸 바이오, 인크. | 헤테로시클릭 glp-1 효능제 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8222261B2 (en) * | 2006-07-13 | 2012-07-17 | GlaxoSmithKline, LLC | Chemical compounds |
| KR101889993B1 (ko) | 2010-09-10 | 2018-08-20 | 시오노기세야쿠 가부시키가이샤 | Ａｍｐｋ 활성화 작용을 갖는 헤테로환 축합 이미다졸 유도체 |
| CA2826649C (en) * | 2011-02-25 | 2016-07-26 | Merck Sharp & Dohme Corp. | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
| ES2755087T3 (es) * | 2012-08-22 | 2020-04-21 | Merck Sharp & Dohme | Derivados de benzimidazol hexahidrofuro[3,2-b]furano útiles como activadores de proteína cinasa activada por AMP |
| EP2888005B1 (en) * | 2012-08-22 | 2019-04-03 | Merck Sharp & Dohme Corp. | Novel azabenzimidazole hexahydrofuro[3,2-b]furan derivatives |
| WO2014069426A1 (ja) * | 2012-10-31 | 2014-05-08 | 塩野義製薬株式会社 | Ａｍｐｋ活性化作用を有するベンズイミダゾールおよびアザベンズイミダゾール誘導体 |
-
2014
- 2014-07-14 CN CN201480040799.5A patent/CN105377857B/zh active Active
- 2014-07-14 HU HUE14738531A patent/HUE038261T2/hu unknown
- 2014-07-14 KR KR1020167004147A patent/KR20160033749A/ko not_active Withdrawn
- 2014-07-14 AU AU2014292236A patent/AU2014292236B2/en not_active Ceased
- 2014-07-14 EP EP14738531.4A patent/EP3022210B1/en active Active
- 2014-07-14 MX MX2016000547A patent/MX359040B/es active IP Right Grant
- 2014-07-14 DK DK14738531.4T patent/DK3022210T3/en active
- 2014-07-14 CA CA2918401A patent/CA2918401A1/en not_active Abandoned
- 2014-07-14 PL PL14738531T patent/PL3022210T3/pl unknown
- 2014-07-14 TR TR2018/06860T patent/TR201806860T4/tr unknown
- 2014-07-14 ES ES14738531.4T patent/ES2669543T3/es active Active
- 2014-07-14 JP JP2016526557A patent/JP6491656B2/ja active Active
- 2014-07-14 EA EA201600113A patent/EA032195B1/ru not_active IP Right Cessation
- 2014-07-14 WO PCT/EP2014/065004 patent/WO2015007669A1/en not_active Ceased
- 2014-07-15 US US14/331,359 patent/US9492436B2/en active Active
- 2014-07-16 AR ARP140102623A patent/AR096936A1/es unknown
- 2014-07-16 TW TW103124425A patent/TW201546076A/zh unknown
- 2014-07-17 UY UY0001035668A patent/UY35668A/es unknown
-
2016
- 2016-01-07 CL CL2016000026A patent/CL2016000026A1/es unknown
- 2016-01-14 PH PH12016500092A patent/PH12016500092B1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017523226A5 (cg-RX-API-DMAC10.html) | ||
| AU2020305979B2 (en) | Method for treating idiopathic pulmonary fibrosis | |
| CN104220053B (zh) | cAMP直接活化交换蛋白(EPAC)的调节剂 | |
| AU2014251087B2 (en) | Formulations of oxabicycloheptanes and oxabicycloheptenes | |
| JP2016508506A5 (cg-RX-API-DMAC10.html) | ||
| KR20170095882A (ko) | 트리아졸로피리미딘 화합물 및 그의 용도 | |
| TWI510484B (zh) | 用於預防及／或治療因化學治療或放射治療所引起之嘔吐的σ配子 | |
| JP2008513514A5 (cg-RX-API-DMAC10.html) | ||
| JP2017513942A (ja) | Ｍｅｒｔｋ特異的ピロロピリミジン化合物 | |
| CN111214471A (zh) | 药物组合物及其用途 | |
| JP2021505575A5 (cg-RX-API-DMAC10.html) | ||
| JP2016515110A5 (cg-RX-API-DMAC10.html) | ||
| JP2014505107A5 (cg-RX-API-DMAC10.html) | ||
| WO2011161216A1 (en) | Heteroaryl compounds and compositions as protein kinase inhibitors | |
| JP2018502133A5 (cg-RX-API-DMAC10.html) | ||
| JP2012526772A5 (cg-RX-API-DMAC10.html) | ||
| TW201026684A (en) | Phosphodiesterase type III (PDE III) inhibitors or Ca2+ -sensitizing agents for the treatment of hypertrophic cardiomyopathy | |
| US20150087886A1 (en) | Novel bifunctional metnase/intnase inhibitors and related compositions and methods of treatment of cancer | |
| JP2018502135A5 (cg-RX-API-DMAC10.html) | ||
| JP2016535049A5 (cg-RX-API-DMAC10.html) | ||
| CA2797762A1 (en) | Imidazo[1,2-a]pyridine derivative | |
| WO2023111996A1 (en) | Compositions and methods of making and using small molecules in the treatment of cancer | |
| US20130289047A1 (en) | Heteroarylthio derivatives and analogues | |
| JP2011509942A5 (cg-RX-API-DMAC10.html) | ||
| AR101364A1 (es) | Derivado de ácido azolcarboxílico |