|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
DK2556171T3
(en)
|
2010-04-05 |
2015-12-14 |
Prognosys Biosciences Inc |
Spatially CODED BIOLOGICAL ASSAYS
|
|
US20190300945A1
(en)
|
2010-04-05 |
2019-10-03 |
Prognosys Biosciences, Inc. |
Spatially Encoded Biological Assays
|
|
US10787701B2
(en)
|
2010-04-05 |
2020-09-29 |
Prognosys Biosciences, Inc. |
Spatially encoded biological assays
|
|
CA2865575C
(en)
|
2012-02-27 |
2024-01-16 |
Cellular Research, Inc. |
Compositions and kits for molecular counting
|
|
US9951386B2
(en)
|
2014-06-26 |
2018-04-24 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US9701998B2
(en)
|
2012-12-14 |
2017-07-11 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US11591637B2
(en)
|
2012-08-14 |
2023-02-28 |
10X Genomics, Inc. |
Compositions and methods for sample processing
|
|
KR102090851B1
(ko)
|
2012-08-14 |
2020-03-19 |
10엑스 제노믹스, 인크. |
마이크로캡슐 조성물 및 방법
|
|
US10323279B2
(en)
|
2012-08-14 |
2019-06-18 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10752949B2
(en)
|
2012-08-14 |
2020-08-25 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10273541B2
(en)
|
2012-08-14 |
2019-04-30 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10400280B2
(en)
|
2012-08-14 |
2019-09-03 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
WO2014060483A1
(en)
|
2012-10-17 |
2014-04-24 |
Spatial Transcriptomics Ab |
Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
|
|
CA2894694C
(en)
|
2012-12-14 |
2023-04-25 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10533221B2
(en)
|
2012-12-14 |
2020-01-14 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
DK2954065T3
(da)
|
2013-02-08 |
2021-09-06 |
10X Genomics Inc |
Opdeling og bearbejdning af analytter og andre arter
|
|
WO2014205126A1
(en)
|
2013-06-19 |
2014-12-24 |
The Regents Of The University Of California |
Chemical structures for localized delivery of therapeutic agents
|
|
US9868979B2
(en)
|
2013-06-25 |
2018-01-16 |
Prognosys Biosciences, Inc. |
Spatially encoded biological assays using a microfluidic device
|
|
ES2857908T3
(es)
|
2013-08-28 |
2021-09-29 |
Becton Dickinson Co |
Análisis masivamente paralelo de células individuales
|
|
AU2015229014B2
(en)
|
2014-03-14 |
2019-07-25 |
The Regents Of The University Of California |
TCO conjugates and methods for delivery of therapeutic agents
|
|
KR102596508B1
(ko)
|
2014-04-10 |
2023-10-30 |
10엑스 제노믹스, 인크. |
시약을 캡슐화 및 구획화하기 위한 유체 디바이스, 시스템, 및 방법, 및 이의 응용
|
|
US9909167B2
(en)
|
2014-06-23 |
2018-03-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
On-slide staining by primer extension
|
|
MX2016016904A
(es)
|
2014-06-26 |
2017-03-27 |
10X Genomics Inc |
Analisis de secuencias de acidos nucleicos.
|
|
US12312640B2
(en)
|
2014-06-26 |
2025-05-27 |
10X Genomics, Inc. |
Analysis of nucleic acid sequences
|
|
KR102531677B1
(ko)
|
2014-06-26 |
2023-05-10 |
10엑스 제노믹스, 인크. |
개별 세포 또는 세포 개체군으로부터 핵산을 분석하는 방법
|
|
KR102321863B1
(ko)
|
2015-01-12 |
2021-11-08 |
10엑스 제노믹스, 인크. |
핵산 시퀀싱 라이브러리의 제조 방법 및 시스템 및 이를 이용하여 제조한 라이브러리
|
|
EP4286516A3
(en)
|
2015-02-24 |
2024-03-06 |
10X Genomics, Inc. |
Partition processing methods and systems
|
|
WO2016138496A1
(en)
|
2015-02-27 |
2016-09-01 |
Cellular Research, Inc. |
Spatially addressable molecular barcoding
|
|
ES2934982T3
(es)
|
2015-03-30 |
2023-02-28 |
Becton Dickinson Co |
Métodos para la codificación con códigos de barras combinatorios
|
|
EP4282977B1
(en)
|
2015-04-10 |
2024-06-05 |
10x Genomics Sweden AB |
Spatially distinguished, multiplex nucleic acid analysis of biological specimens
|
|
US11390914B2
(en)
|
2015-04-23 |
2022-07-19 |
Becton, Dickinson And Company |
Methods and compositions for whole transcriptome amplification
|
|
AU2016297513B2
(en)
*
|
2015-07-17 |
2021-02-25 |
Board Of Regents, The University Of Texas System |
Simultaneous quantification of a plurality of proteins in a user-defined region of a cross-sectioned tissue
|
|
EP3325650B1
(en)
|
2015-07-17 |
2024-01-03 |
Nanostring Technologies, Inc. |
Simultaneous quantification of gene expression in a user-defined region of a cross-sectioned tissue
|
|
CN117567535A
(zh)
|
2015-09-10 |
2024-02-20 |
坦伯公司 |
生物正交组合物
|
|
CN108026524A
(zh)
|
2015-09-11 |
2018-05-11 |
赛卢拉研究公司 |
用于核酸文库标准化的方法和组合物
|
|
US11371094B2
(en)
|
2015-11-19 |
2022-06-28 |
10X Genomics, Inc. |
Systems and methods for nucleic acid processing using degenerate nucleotides
|
|
DK3882357T3
(da)
|
2015-12-04 |
2022-08-29 |
10X Genomics Inc |
Fremgangsmåder og sammensætninger til analyse af nukleinsyrer
|
|
WO2017165887A1
(en)
*
|
2016-03-25 |
2017-09-28 |
The General Hospital Corporation |
Polarization-based fluorescent nucleic acid detection
|
|
US10301677B2
(en)
|
2016-05-25 |
2019-05-28 |
Cellular Research, Inc. |
Normalization of nucleic acid libraries
|
|
US10202641B2
(en)
|
2016-05-31 |
2019-02-12 |
Cellular Research, Inc. |
Error correction in amplification of samples
|
|
US10640763B2
(en)
|
2016-05-31 |
2020-05-05 |
Cellular Research, Inc. |
Molecular indexing of internal sequences
|
|
CN110312808A
(zh)
*
|
2016-06-30 |
2019-10-08 |
拜欧亿思有限公司 |
双链核酸信号探针以及利用上述双链核酸信号探针的靶分子检测方法
|
|
US11702687B2
(en)
|
2016-07-18 |
2023-07-18 |
Yale University |
Multiplex detection of intracellular or surface molecular targets in single cells
|
|
WO2018022809A1
(en)
*
|
2016-07-27 |
2018-02-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Highly-multiplexed fluorescent imaging
|
|
KR102363716B1
(ko)
*
|
2016-09-26 |
2022-02-18 |
셀룰러 리서치, 인크. |
바코딩된 올리고뉴클레오티드 서열을 갖는 시약을 이용한 단백질 발현의 측정
|
|
ES2870639T3
(es)
|
2016-10-24 |
2021-10-27 |
Geneinfosec Inc |
Ocultación de información presente en los ácidos nucleicos
|
|
JP7048617B2
(ja)
|
2016-12-19 |
2022-04-05 |
ヴェンタナ メディカル システムズ， インク． |
ペプチド核酸コンジュゲート
|
|
US10815525B2
(en)
|
2016-12-22 |
2020-10-27 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10550429B2
(en)
|
2016-12-22 |
2020-02-04 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10011872B1
(en)
|
2016-12-22 |
2018-07-03 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
CN117512066A
(zh)
|
2017-01-30 |
2024-02-06 |
10X基因组学有限公司 |
用于基于微滴的单细胞条形编码的方法和系统
|
|
US11319583B2
(en)
|
2017-02-01 |
2022-05-03 |
Becton, Dickinson And Company |
Selective amplification using blocking oligonucleotides
|
|
US10995333B2
(en)
|
2017-02-06 |
2021-05-04 |
10X Genomics, Inc. |
Systems and methods for nucleic acid preparation
|
|
US11753743B2
(en)
|
2017-02-13 |
2023-09-12 |
Yale University |
High-throughput single-cell polyomics
|
|
WO2018187740A1
(en)
|
2017-04-07 |
2018-10-11 |
Shasqi, Inc. |
Bioorthogonal compositions
|
|
WO2018203575A1
(ja)
|
2017-05-02 |
2018-11-08 |
国立大学法人 東京大学 |
細胞またはその由来物の動的変化のモニタリング方法およびそれを用いた細胞分類方法
|
|
EP3445876B1
(en)
|
2017-05-26 |
2023-07-05 |
10X Genomics, Inc. |
Single cell analysis of transposase accessible chromatin
|
|
US10400235B2
(en)
|
2017-05-26 |
2019-09-03 |
10X Genomics, Inc. |
Single cell analysis of transposase accessible chromatin
|
|
WO2018226293A1
(en)
|
2017-06-05 |
2018-12-13 |
Becton, Dickinson And Company |
Sample indexing for single cells
|
|
US11084037B2
(en)
|
2017-09-25 |
2021-08-10 |
Plexium, Inc. |
Oligonucleotide encoded chemical libraries
|
|
US20200256862A1
(en)
*
|
2017-10-23 |
2020-08-13 |
Massachusetts Institute Of Technology |
Functionalized solid support
|
|
SG11201913654QA
(en)
|
2017-11-15 |
2020-01-30 |
10X Genomics Inc |
Functionalized gel beads
|
|
US10829815B2
(en)
|
2017-11-17 |
2020-11-10 |
10X Genomics, Inc. |
Methods and systems for associating physical and genetic properties of biological particles
|
|
CN118818037A
(zh)
|
2017-12-12 |
2024-10-22 |
10X基因组学有限公司 |
用于单细胞处理的系统和方法
|
|
EP3727470B1
(en)
|
2017-12-18 |
2024-11-20 |
Ventana Medical Systems, Inc. |
Peptide nucleic acid conjugates
|
|
JP7158642B2
(ja)
*
|
2018-01-16 |
2022-10-24 |
国立大学法人山梨大学 |
質量分析装置及び質量分析システム
|
|
KR101911859B1
(ko)
*
|
2018-02-02 |
2018-12-28 |
주식회사 바이오이즈 |
이중가닥 핵산 신호 프로브 및 이를 이용한 표적분자의 검출방법
|
|
CN112005115A
(zh)
|
2018-02-12 |
2020-11-27 |
10X基因组学有限公司 |
表征来自单个细胞或细胞群体的多种分析物的方法
|
|
WO2019157445A1
(en)
|
2018-02-12 |
2019-08-15 |
Nanostring Technologies, Inc. |
Biomolecular probes and methods of detecting gene and protein expression
|
|
WO2019195166A1
(en)
|
2018-04-06 |
2019-10-10 |
10X Genomics, Inc. |
Systems and methods for quality control in single cell processing
|
|
WO2019213294A1
(en)
|
2018-05-03 |
2019-11-07 |
Becton, Dickinson And Company |
High throughput multiomics sample analysis
|
|
WO2019213237A1
(en)
|
2018-05-03 |
2019-11-07 |
Becton, Dickinson And Company |
Molecular barcoding on opposite transcript ends
|
|
CN110456034B
(zh)
*
|
2018-05-07 |
2022-07-22 |
上海市第十人民医院 |
一种循环肿瘤细胞的检测方法
|
|
WO2019217758A1
(en)
|
2018-05-10 |
2019-11-14 |
10X Genomics, Inc. |
Methods and systems for molecular library generation
|
|
WO2019226631A1
(en)
*
|
2018-05-21 |
2019-11-28 |
The Regents Of The University Of California |
Single cell mapping and transcriptome analysis
|
|
US20200020419A1
(en)
*
|
2018-07-16 |
2020-01-16 |
Flagship Pioneering Innovations Vi, Llc. |
Methods of analyzing cells
|
|
US20200032335A1
(en)
|
2018-07-27 |
2020-01-30 |
10X Genomics, Inc. |
Systems and methods for metabolome analysis
|
|
CN118853827A
(zh)
|
2018-10-01 |
2024-10-29 |
贝克顿迪金森公司 |
确定5’转录物序列
|
|
CN112969789A
(zh)
|
2018-11-08 |
2021-06-15 |
贝克顿迪金森公司 |
使用随机引发的单细胞全转录组分析
|
|
US12529094B2
(en)
|
2018-12-10 |
2026-01-20 |
10X Genomics, Inc. |
Imaging system hardware
|
|
US11459607B1
(en)
|
2018-12-10 |
2022-10-04 |
10X Genomics, Inc. |
Systems and methods for processing-nucleic acid molecules from a single cell using sequential co-partitioning and composite barcodes
|
|
WO2020123311A2
(en)
|
2018-12-10 |
2020-06-18 |
10X Genomics, Inc. |
Resolving spatial arrays using deconvolution
|
|
EP3894552B1
(en)
|
2018-12-13 |
2026-01-28 |
Becton, Dickinson and Company |
Selective extension in single cell whole transcriptome analysis
|
|
US11649485B2
(en)
|
2019-01-06 |
2023-05-16 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
US11926867B2
(en)
|
2019-01-06 |
2024-03-12 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
US11845983B1
(en)
|
2019-01-09 |
2023-12-19 |
10X Genomics, Inc. |
Methods and systems for multiplexing of droplet based assays
|
|
ES2945227T3
(es)
|
2019-01-23 |
2023-06-29 |
Becton Dickinson Co |
Oligonucleótidos asociados con anticuerpos
|
|
US20220056498A1
(en)
|
2019-01-25 |
2022-02-24 |
President And Fellows Of Harvard College |
Compositions and method for synthesizing nucleic acids
|
|
US11851683B1
(en)
|
2019-02-12 |
2023-12-26 |
10X Genomics, Inc. |
Methods and systems for selective analysis of cellular samples
|
|
EP3924506A1
(en)
|
2019-02-14 |
2021-12-22 |
Becton Dickinson and Company |
Hybrid targeted and whole transcriptome amplification
|
|
EP3931354A1
(en)
|
2019-02-28 |
2022-01-05 |
10X Genomics, Inc. |
Profiling of biological analytes with spatially barcoded oligonucleotide arrays
|
|
EP3938538A1
(en)
|
2019-03-15 |
2022-01-19 |
10X Genomics, Inc. |
Methods for using spatial arrays for single cell sequencing
|
|
WO2020198071A1
(en)
|
2019-03-22 |
2020-10-01 |
10X Genomics, Inc. |
Three-dimensional spatial analysis
|
|
JP7183899B2
(ja)
*
|
2019-03-25 |
2022-12-06 |
株式会社Ｊｖｃケンウッド |
分析装置及び分析方法
|
|
US20220155308A1
(en)
*
|
2019-03-27 |
2022-05-19 |
Fluidigm Canada Inc. |
Lyophilized antibody panel
|
|
US11965208B2
(en)
|
2019-04-19 |
2024-04-23 |
Becton, Dickinson And Company |
Methods of associating phenotypical data and single cell sequencing data
|
|
WO2020243579A1
(en)
|
2019-05-30 |
2020-12-03 |
10X Genomics, Inc. |
Methods of detecting spatial heterogeneity of a biological sample
|
|
CN114051534B
(zh)
|
2019-07-22 |
2025-02-21 |
贝克顿迪金森公司 |
单细胞染色质免疫沉淀测序测定
|
|
KR102406463B1
(ko)
*
|
2019-09-03 |
2022-06-10 |
재단법인 오송첨단의료산업진흥재단 |
단백질 생산성 향상을 위한 개별 바코딩 시스템 도입한 시그널 펩타이드 초고속 선별방법
|
|
US12235262B1
(en)
|
2019-09-09 |
2025-02-25 |
10X Genomics, Inc. |
Methods and systems for single cell protein analysis
|
|
EP4055185A1
(en)
|
2019-11-08 |
2022-09-14 |
10X Genomics, Inc. |
Spatially-tagged analyte capture agents for analyte multiplexing
|
|
CN114729350A
(zh)
|
2019-11-08 |
2022-07-08 |
贝克顿迪金森公司 |
使用随机引发获得用于免疫组库测序的全长v(d)j信息
|
|
ES3024383T3
(en)
|
2019-11-13 |
2025-06-04 |
10X Genomics Inc |
Generating capture probes for spatial analysis
|
|
AU2020400056A1
(en)
|
2019-12-12 |
2022-07-07 |
President And Fellows Of Harvard College |
Compositions and methods for light-directed biomolecular barcoding
|
|
EP4090763B1
(en)
|
2020-01-13 |
2024-12-04 |
Becton Dickinson and Company |
Methods and compositions for quantitation of proteins and rna
|
|
US12577702B2
(en)
|
2020-01-28 |
2026-03-17 |
Plexium, Inc. |
Oligonucleotide encoded chemical libraries, related systems, devices, and methods for detecting, analyzing, quantifying, and testing biologics/genetics
|
|
ES2993319T3
(en)
|
2020-01-29 |
2024-12-27 |
Becton Dickinson Co |
Barcoded wells for spatial mapping of single cells through sequencing
|
|
US12399123B1
(en)
|
2020-02-14 |
2025-08-26 |
10X Genomics, Inc. |
Spatial targeting of analytes
|
|
CN115052995B
(zh)
*
|
2020-02-14 |
2025-05-06 |
索尼集团公司 |
分析方法、分析系统及分析表面
|
|
US12281357B1
(en)
|
2020-02-14 |
2025-04-22 |
10X Genomics, Inc. |
In situ spatial barcoding
|
|
EP4111168A1
(en)
|
2020-02-25 |
2023-01-04 |
Becton Dickinson and Company |
Bi-specific probes to enable the use of single-cell samples as single color compensation control
|
|
US20240018607A1
(en)
*
|
2020-03-31 |
2024-01-18 |
Logicink Corporation |
Molecular beacons
|
|
EP4143333A1
(en)
|
2020-04-30 |
2023-03-08 |
Dimensiongen |
Devices and methods for macromolecular manipulation
|
|
CN115605614A
(zh)
|
2020-05-14 |
2023-01-13 |
贝克顿迪金森公司（Us） |
用于免疫组库谱分析的引物
|
|
WO2021243285A1
(en)
*
|
2020-05-29 |
2021-12-02 |
Seer, Inc. |
Systems and methods for rapid identification of proteins
|
|
WO2021247593A1
(en)
|
2020-06-02 |
2021-12-09 |
Becton, Dickinson And Company |
Oligonucleotides and beads for 5 prime gene expression assay
|
|
EP4421186B1
(en)
|
2020-06-08 |
2025-08-13 |
10X Genomics, Inc. |
Methods of determining a surgical margin and methods of use thereof
|
|
US11981960B1
(en)
|
2020-07-06 |
2024-05-14 |
10X Genomics, Inc. |
Spatial analysis utilizing degradable hydrogels
|
|
US11932901B2
(en)
|
2020-07-13 |
2024-03-19 |
Becton, Dickinson And Company |
Target enrichment using nucleic acid probes for scRNAseq
|
|
US12391940B2
(en)
|
2020-07-31 |
2025-08-19 |
Becton, Dickinson And Company |
Single cell assay for transposase-accessible chromatin
|
|
US12553898B1
(en)
|
2020-08-10 |
2026-02-17 |
10X Genomics, Inc. |
Fluorescent hybridization of antibody-oligonucleotide for multiplexing and signal amplification
|
|
WO2022109343A1
(en)
|
2020-11-20 |
2022-05-27 |
Becton, Dickinson And Company |
Profiling of highly expressed and lowly expressed proteins
|
|
JPWO2022118862A1
(show.php)
*
|
2020-12-01 |
2022-06-09 |
|
|
|
EP4263859A1
(en)
|
2020-12-15 |
2023-10-25 |
Becton, Dickinson and Company |
Single cell secretome analysis
|
|
WO2022140028A1
(en)
|
2020-12-21 |
2022-06-30 |
10X Genomics, Inc. |
Methods, compositions, and systems for capturing probes and/or barcodes
|
|
US20240076723A1
(en)
|
2020-12-30 |
2024-03-07 |
10X Genomics, Inc. |
Cleavage of capture probes for spatial analysis
|
|
WO2022198068A1
(en)
|
2021-03-18 |
2022-09-22 |
10X Genomics, Inc. |
Multiplex capture of gene and protein expression from a biological sample
|
|
US20240255425A1
(en)
*
|
2021-05-19 |
2024-08-01 |
Leica Microsystems Cms Gmbh |
Marker, method and device for analyzing a biological sample
|
|
US20240248082A1
(en)
*
|
2021-05-19 |
2024-07-25 |
Leica Microsystems Cms Gmbh |
Marker, method and device for analyzing a biological sample
|
|
EP4582555A3
(en)
|
2021-06-03 |
2025-10-22 |
10X Genomics, Inc. |
Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
|
|
CN117897613A
(zh)
*
|
2021-08-31 |
2024-04-16 |
贝克顿迪金森公司 |
使用寡核苷酸缀合的抗体的多重蛋白质组学分析
|
|
WO2023102118A2
(en)
|
2021-12-01 |
2023-06-08 |
10X Genomics, Inc. |
Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis
|
|
WO2023147513A2
(en)
*
|
2022-01-28 |
2023-08-03 |
Washington University |
Compositions of autophagy modulating agents and uses thereof
|
|
WO2023250077A1
(en)
|
2022-06-22 |
2023-12-28 |
10X Genomics, Inc. |
Methods, compositions, and systems for capturing probes and/or barcodes
|
|
ES3025190T3
(en)
*
|
2022-09-20 |
2025-06-06 |
Miltenyi Biotec Bv & Co Kg |
Biological conjugates having an photogenerated acidic or basic releasable detection moiety on top of biological tissues
|
|
WO2024064866A2
(en)
*
|
2022-09-22 |
2024-03-28 |
Astrin Biosciences, Inc. |
Tumor cell profiling-based therapeutic targeting of cancer
|
|
WO2024073524A2
(en)
*
|
2022-09-28 |
2024-04-04 |
Massachusetts Institute Of Technology |
High throughput stochastic bio-molecular sensor
|
|
EP4486913B1
(en)
|
2022-12-30 |
2025-07-16 |
10x Genomics, Inc. |
Methods, compositions, and kits for multiple barcoding and/or high-density spatial barcoding
|
|
KR102869006B1
(ko)
*
|
2023-03-14 |
2025-10-14 |
재단법인 아산사회복지재단 |
다중면역형광염색을 이용한 세포 시료에서 표적 단백질을 검출하는 방법
|
|
WO2025049491A1
(en)
*
|
2023-08-29 |
2025-03-06 |
Genopheno, Llc. |
Novel sampling and genetic comparison and analysis of cannabis components for commercial differentiation
|
|
WO2025188805A1
(en)
*
|
2024-03-04 |
2025-09-12 |
University Of Denver |
Blood based rapid diagnostic system for brain hemorrhage detection and associated methods
|
|
US20250329467A1
(en)
*
|
2024-04-23 |
2025-10-23 |
Delfi Diagnostics, Inc. |
Workflows for discovery and deployment of diagnostic assays combining proteomic and genomic information
|