JP2016520846A - 多量体の標的分子の検出に対する粒子ベースの試験において凝集を防ぐ試薬、方法及び装置 - Google Patents

多量体の標的分子の検出に対する粒子ベースの試験において凝集を防ぐ試薬、方法及び装置 Download PDF

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JP2016520846A
JP2016520846A JP2016517724A JP2016517724A JP2016520846A JP 2016520846 A JP2016520846 A JP 2016520846A JP 2016517724 A JP2016517724 A JP 2016517724A JP 2016517724 A JP2016517724 A JP 2016517724A JP 2016520846 A JP2016520846 A JP 2016520846A
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epitope
target analyte
capture entity
detection
capture
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JP2016520846A5 (enExample
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ヘンドリク エフェルス，トーン
ヘンドリク エフェルス，トーン
ウィレム ヨゼ プリンス，メンノ
ウィレム ヨゼ プリンス，メンノ
ハンス ニーウェンハイス，イェルーン
ハンス ニーウェンハイス，イェルーン
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Koninklijke Philips NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
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  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2016517724A 2013-06-06 2014-06-05 多量体の標的分子の検出に対する粒子ベースの試験において凝集を防ぐ試薬、方法及び装置 Pending JP2016520846A (ja)

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Application Number Priority Date Filing Date Title
EP13170722.6 2013-06-06
EP13170722 2013-06-06
PCT/IB2014/061986 WO2014195899A1 (en) 2013-06-06 2014-06-05 Reagents, methods and devices to prevent aggregation in particle based tests for the detection of multimeric target molecules

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JP2016520846A5 JP2016520846A5 (enExample) 2018-01-18

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JP2018197798A Active JP6746866B2 (ja) 2013-06-06 2018-10-19 多量体の標的分子の検出に対する粒子ベースの試験において凝集を防ぐ試薬、方法及び装置

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US (1) US10895571B2 (enExample)
EP (1) EP3004882B1 (enExample)
JP (2) JP2016520846A (enExample)
CN (1) CN105579849B (enExample)
WO (1) WO2014195899A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024542935A (ja) * 2021-10-08 2024-11-19 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 周囲媒体中の生物活性物質の検出

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CN107003307B (zh) 2014-12-18 2020-04-07 豪夫迈·罗氏有限公司 降低干扰的方法
CN109416357B (zh) * 2016-06-30 2022-07-15 西门子医疗系统荷兰有限公司 用于检测包含多个细胞的体液样本中的分析物的设备、系统和方法
WO2018077783A1 (en) 2016-10-24 2018-05-03 Roche Diagnostics Gmbh Immobilized analytes
EP3673268A1 (de) * 2017-08-26 2020-07-01 AJ Innuscreen GmbH Mittel und verfahren zur detektion von analyten mittels makroskopischer granulat-partikel
CN113302492A (zh) * 2019-01-03 2021-08-24 彼克斯赛尔医疗科技有限公司 用于分析流体样品的系统和方法
US12000828B2 (en) 2019-03-25 2024-06-04 Boe Technology Group Co., Ltd. Immunodetection chip, immunodetection device and using method
FR3100338B1 (fr) * 2019-08-30 2022-09-02 Centre Nat Rech Scient Kit et méthode de capture d’une molécule
CN116391126A (zh) 2020-08-07 2023-07-04 维塔生物科技公司 磁性分析物检测的动力学调节

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JP2012215553A (ja) * 2011-03-30 2012-11-08 Toshiba Corp 光導波路型測定システム、測定方法及び光導波路型センサチップ
JP2012230124A (ja) * 1999-01-25 2012-11-22 Minerva Biotechnologies Corp 神経変性疾患における異常型タンパク質凝集の迅速かつ高感度の検出
JP2014533382A (ja) * 2011-05-16 2014-12-11 クゥアルコム・インコーポレイテッドＱｕａｌｃｏｍｍ Ｉｎｃｏｒｐｏｒａｔｅｄ グラフィックス処理ユニットにおけるレンダリングモード選択

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RU2487338C2 (ru) 2006-12-12 2013-07-10 Конинклейке Филипс Электроникс Н.В. Микроэлектронное сенсорное устройство для обнаружения частиц-меток
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WO1992017781A1 (en) * 1991-04-04 1992-10-15 International Murex Technologies Corporation Agglutination assay
JP2012230124A (ja) * 1999-01-25 2012-11-22 Minerva Biotechnologies Corp 神経変性疾患における異常型タンパク質凝集の迅速かつ高感度の検出
JP2005522698A (ja) * 2002-04-10 2005-07-28 レスポンス バイオメディカル コーポレイション 高感度の免疫クロマトグラフィーアッセイ法
JP2012215553A (ja) * 2011-03-30 2012-11-08 Toshiba Corp 光導波路型測定システム、測定方法及び光導波路型センサチップ
JP2014533382A (ja) * 2011-05-16 2014-12-11 クゥアルコム・インコーポレイテッドＱｕａｌｃｏｍｍ Ｉｎｃｏｒｐｏｒａｔｅｄ グラフィックス処理ユニットにおけるレンダリングモード選択

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024542935A (ja) * 2021-10-08 2024-11-19 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 周囲媒体中の生物活性物質の検出
JP7727102B2 (ja) 2021-10-08 2025-08-20 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 周囲媒体中の生物活性物質の検出

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EP3004882A1 (en) 2016-04-13
US20160123965A1 (en) 2016-05-05
US10895571B2 (en) 2021-01-19
WO2014195899A1 (en) 2014-12-11
CN105579849A (zh) 2016-05-11
EP3004882B1 (en) 2018-03-21
CN105579849B (zh) 2019-02-22
JP2019060873A (ja) 2019-04-18
JP6746866B2 (ja) 2020-08-26

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