JP2016516997A5 - - Google Patents

Info

Publication number

JP2016516997A5

JP2016516997A5 JP2016502025A JP2016502025A JP2016516997A5 JP 2016516997 A5 JP2016516997 A5 JP 2016516997A5 JP 2016502025 A JP2016502025 A JP 2016502025A JP 2016502025 A JP2016502025 A JP 2016502025A JP 2016516997 A5 JP2016516997 A5 JP 2016516997A5

Authority

JP

Japan

Prior art keywords

analyte

oxa

reagent

anchor

ctx

Prior art date

2014-03-13

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 239000012491 analyte Substances 0.000 claims description 15
• 239000003153 chemical reaction reagent Substances 0.000 claims description 14
• 238000000034 method Methods 0.000 claims description 9
• 238000001514 detection method Methods 0.000 claims description 7
• 108020004711 Nucleic Acid Probes Proteins 0.000 claims 4
• 239000003550 marker Substances 0.000 claims 4
• 239000002853 nucleic acid probe Substances 0.000 claims 4
• 108090000623 proteins and genes Proteins 0.000 claims 4
• 239000000523 sample Substances 0.000 claims 4
• 230000000295 complement effect Effects 0.000 claims 3
• 108010016299 6'-aminoglycoside acetyltransferase-2''-aminoglycoside phosphotransferase Proteins 0.000 claims 2
• 102100038083 Endosialin Human genes 0.000 claims 2
• 241000588724 Escherichia coli Species 0.000 claims 2
• 101000884275 Homo sapiens Endosialin Proteins 0.000 claims 2
• 108091034117 Oligonucleotide Proteins 0.000 claims 2
• 101710202686 Penicillin-sensitive transpeptidase Proteins 0.000 claims 2
• 108010059993 Vancomycin Proteins 0.000 claims 2
• 229940126575 aminoglycoside Drugs 0.000 claims 2
• 230000000844 anti-bacterial effect Effects 0.000 claims 2
• 230000000845 anti-microbial effect Effects 0.000 claims 2
• 239000004599 antimicrobial Substances 0.000 claims 2
• 108010002829 beta-lactamase TEM-3 Proteins 0.000 claims 2
• 101150049515 bla gene Proteins 0.000 claims 2
• YZBQHRLRFGPBSL-RXMQYKEDSA-N carbapenem Chemical compound C1C=CN2C(=O)C[C@H]21 YZBQHRLRFGPBSL-RXMQYKEDSA-N 0.000 claims 2
• 239000003120 macrolide antibiotic agent Substances 0.000 claims 2
• 102000004169 proteins and genes Human genes 0.000 claims 2
• 101150114434 vanA gene Proteins 0.000 claims 2
• 101150037181 vanB gene Proteins 0.000 claims 2
• 229960003165 vancomycin Drugs 0.000 claims 2
• MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 claims 2
• MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 claims 2
• 150000003952 β-lactams Chemical class 0.000 claims 2
• 239000011324 bead Substances 0.000 description 3
• 230000008878 coupling Effects 0.000 description 1
• 238000010168 coupling process Methods 0.000 description 1
• 238000005859 coupling reaction Methods 0.000 description 1