DK2210100T3 - Fprbedrede fret-prober og anvendelse deraf - Google Patents

Fprbedrede fret-prober og anvendelse deraf

Info

Publication number
DK2210100T3
DK2210100T3 DK08851189.4T DK08851189T DK2210100T3 DK 2210100 T3 DK2210100 T3 DK 2210100T3 DK 08851189 T DK08851189 T DK 08851189T DK 2210100 T3 DK2210100 T3 DK 2210100T3
Authority
DK
Denmark
Prior art keywords
probe
reactive group
fret probes
reactive
improved fret
Prior art date
Application number
DK08851189.4T
Other languages
English (en)
Inventor
Dongen Jacobus Johannes Maria Van
De Matos Correia E Vale Jose Alberto Orfao
Original Assignee
Univ Erasmus Medical Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Erasmus Medical Ct filed Critical Univ Erasmus Medical Ct
Application granted granted Critical
Publication of DK2210100T3 publication Critical patent/DK2210100T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK08851189.4T 2007-11-21 2008-11-21 Fprbedrede fret-prober og anvendelse deraf DK2210100T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US411207P 2007-11-21 2007-11-21
PCT/NL2008/050737 WO2009067009A1 (en) 2007-11-21 2008-11-21 Improved fret-probes and use thereof

Publications (1)

Publication Number Publication Date
DK2210100T3 true DK2210100T3 (da) 2011-09-05

Family

ID=40317061

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08851189.4T DK2210100T3 (da) 2007-11-21 2008-11-21 Fprbedrede fret-prober og anvendelse deraf

Country Status (14)

Country Link
US (1) US20120003632A1 (da)
EP (1) EP2210100B1 (da)
JP (1) JP2011505549A (da)
KR (1) KR101623992B1 (da)
CN (1) CN101868728A (da)
AT (1) ATE511649T1 (da)
AU (1) AU2008326922B2 (da)
BR (1) BRPI0819739A2 (da)
CA (1) CA2706477C (da)
DK (1) DK2210100T3 (da)
EA (1) EA201000836A1 (da)
ES (1) ES2367232T3 (da)
WO (1) WO2009067009A1 (da)
ZA (1) ZA201003394B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2884100T3 (es) * 2011-11-11 2021-12-10 Eli N Glezer Procedimientos de ensayo asistidos por coagente de unión
CN104619840A (zh) * 2012-07-05 2015-05-13 日本国立癌症研究中心 Fgfr2融合基因
CN103207166B (zh) * 2012-12-25 2015-06-03 西安交通大学 用于快速检测atp的荧光共振体系的制备方法
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
US10379741B2 (en) * 2014-04-17 2019-08-13 Seagate Technology Llc Dynamic storage device region provisioning
CN103937490B (zh) * 2014-04-24 2015-07-29 辽宁大学 一种检测线粒体中硫离子的荧光探针及其应用
WO2015175856A1 (en) 2014-05-15 2015-11-19 Meso Scale Technologies, Llc. Improved assay methods
JP6640843B2 (ja) * 2014-09-30 2020-02-05 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 第１及び第２のエピトープの空間的近接を検出する方法
CN106290988A (zh) * 2015-05-25 2017-01-04 中国科学院上海应用物理研究所 饱和共振能量转移超分辨探针及其制备方法和应用
US20180171382A1 (en) * 2015-06-26 2018-06-21 Albert-Ludwigs-Universität Freiburg Branched proximity hybridization assay
CN105136761A (zh) * 2015-09-06 2015-12-09 常州大学 一种检测量子点表面多肽数量的方法
PL3368682T3 (pl) * 2015-10-30 2020-05-18 F. Hoffmann-La Roche Ag Sposoby pomiaru aktywności czynnika D i siły działania inhibitorów czynnika D
CA3029178C (en) * 2016-06-30 2022-07-19 Biois Co.,Ltd Double-stranded nucleic acid signal probe and method for detecting target molecule using same
CN106554378B (zh) * 2016-10-26 2019-06-21 广西大学 两/三簇糖基罗丹明衍生物及其制备方法和应用
EP3554556B1 (en) 2016-12-19 2022-03-09 Ventana Medical Systems, Inc. Peptide nucleic acid conjugates
CN107353903B (zh) * 2017-06-28 2019-05-10 武汉大学 一种合成染料修饰dna功能化含镉量子点的方法及其应用
EP3727470A1 (en) 2017-12-18 2020-10-28 Ventana Medical Systems, Inc. Peptide nucleic acid conjugates
US11604186B2 (en) * 2018-10-17 2023-03-14 Molecular Devices (Austria) GmbH Real time western blot assays utilizing fluorescence resonance energy transfer (FRET)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714331A (en) * 1991-05-24 1998-02-03 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US5804384A (en) * 1996-12-06 1998-09-08 Vysis, Inc. Devices and methods for detecting multiple analytes in samples
EP1222432A1 (en) * 1999-09-27 2002-07-17 Array Bioscience Corporation Fractal absorber for heat pipes with broad range heat radiation absorptivity
US6511809B2 (en) * 2000-06-13 2003-01-28 E. I. Du Pont De Nemours And Company Method for the detection of an analyte by means of a nucleic acid reporter
JP2001245699A (ja) * 2001-02-01 2001-09-11 Hitachi Ltd 核酸の検出方法
WO2002088733A1 (fr) * 2001-04-23 2002-11-07 Eiken Kagaku Kabushiki Kaisha Methode d'analyse faisant intervenir une interaction intermoleculaire par rapporteur (marqueur)
ATE480774T1 (de) * 2002-11-07 2010-09-15 Univ Erasmus Verfahren und proben zur detektion des tumor spezifische fusion proteinen
DE60320828D1 (de) * 2002-11-07 2008-06-19 Univ Erasmus Fret proben und verfahren zur erkennung aufeinander einwirkeneden moleküle
WO2005059509A2 (en) * 2003-12-12 2005-06-30 Saint Louis University Biosensors for detecting macromolecules and other analytes
JP4626350B2 (ja) * 2005-03-22 2011-02-09 ソニー株式会社 ハイブリダイゼーション検出に適する反応部などを有する流路系、該流路系を用いるハイブリダイゼーション検出装置
US7795009B2 (en) * 2005-06-15 2010-09-14 Saint Louis University Three-component biosensors for detecting macromolecules and other analytes

Also Published As

Publication number Publication date
ZA201003394B (en) 2011-02-23
WO2009067009A1 (en) 2009-05-28
EP2210100B1 (en) 2011-06-01
ES2367232T3 (es) 2011-10-31
BRPI0819739A2 (pt) 2017-05-09
EA201000836A1 (ru) 2010-12-30
AU2008326922B2 (en) 2013-11-28
ATE511649T1 (de) 2011-06-15
KR20100105605A (ko) 2010-09-29
JP2011505549A (ja) 2011-02-24
CA2706477C (en) 2016-09-13
EP2210100A1 (en) 2010-07-28
AU2008326922A1 (en) 2009-05-28
US20120003632A1 (en) 2012-01-05
KR101623992B1 (ko) 2016-05-24
CA2706477A1 (en) 2009-05-28
CN101868728A (zh) 2010-10-20

Similar Documents

Publication Publication Date Title
DK2210100T3 (da) Fprbedrede fret-prober og anvendelse deraf
CY1122210T1 (el) Ανθρωπινα αντισωματα anti-sod1
CY1121536T1 (el) Ανθρωπινα αντισωματα εναντι-αλφα-συνουκλεϊνης
DE60320828D1 (de) Fret proben und verfahren zur erkennung aufeinander einwirkeneden moleküle
TR201910213T4 (tr) Disülfürle stabilize edilmiş çok değerlikli antikorlar.
BR112012031071A2 (pt) 8-proteínas de ligação à il-1
MXPA05013729A (es) Compuestos diazoicos disimetricos con grupos 2-piridinio y brazo de enlace cationico o no cationico, composiciones que incluyen dichos compuestos, procedimiento de coloracion y dispositivo.
ECSP088733A (es) Anticuerpos anti-5t4 y usos de los mismos
ES2570731T3 (es) Método de detección de cáncer
ATE527385T1 (de) Mit tumoren assoziierte genetische variationen
CY1112553T1 (el) Ανοσοπροσδιορισμοι υψηλης ευαισθησιας και κιτια για τον προσδιορισμο πεπτιδιων και πρωτεϊνων βιολογικου ενδιαφεροντος
PT932830E (pt) Ensaio de transferencia de energia de fluorescencia por interaccao de ligados num filme lipidico
EA201791610A1 (ru) Проникающие в клетку антитела
WO2012159072A3 (en) Fluorescent molecular probes for use in assays that measure test compound competitive binding with sam-utilizing proteins
ES2352050T5 (es) Metodo y sondas para la deteccion de una proteina de fusion especifica de un tumor.
CN103045469A (zh) 多通道环介导核酸等温扩增定量检测器
BRPI0712273A2 (pt) Anticorpos isolados, polipeptídeos imunoglobulinas, anticorpo hepsina, molécula de ácido nucléico, célula hospedeira, linhagem celular, métodos para produzir o anticorpo, para diagnosticar a presença de hepsina, tratar uma doença, para monitorar a doença residual, para detectar o estado da doença, para diagnosticar uma disfunção, composição, arranjo ou chip de proteína e kit
WO2008117792A1 (ja) アデノシン三リン酸測定のための蛍光標識融合タンパク質
WO2009055387A8 (en) Polymerized conjugates for biological applications
DE602005023784D1 (de) Blockierter enzymsondenkomplex
CN102154276B (zh) 一种断端对接式发夹型dna探针
DE602006010187D1 (de) Einzelsequenzhybridisierungssonden
Jeong et al. Protein binders specific for immunoglobulin g from different species for immunoassays and multiplex imaging
WO2008143702A3 (en) Anti-mrp3 antibodies and methods of use
WO2005100553A3 (en) Method for assessment of cytotoxic lymphocyte activity