JP2016514160A5 - - Google Patents
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- Publication number
- JP2016514160A5 JP2016514160A5 JP2016502881A JP2016502881A JP2016514160A5 JP 2016514160 A5 JP2016514160 A5 JP 2016514160A5 JP 2016502881 A JP2016502881 A JP 2016502881A JP 2016502881 A JP2016502881 A JP 2016502881A JP 2016514160 A5 JP2016514160 A5 JP 2016514160A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- cancer
- compound
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361783290P | 2013-03-14 | 2013-03-14 | |
| US61/783,290 | 2013-03-14 | ||
| PCT/US2014/028730 WO2014153023A1 (en) | 2013-03-14 | 2014-03-14 | 5-bromo-indirubins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016514160A JP2016514160A (ja) | 2016-05-19 |
| JP2016514160A5 true JP2016514160A5 (enExample) | 2017-04-13 |
| JP6422936B2 JP6422936B2 (ja) | 2018-11-14 |
Family
ID=51581389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502881A Expired - Fee Related JP6422936B2 (ja) | 2013-03-14 | 2014-03-14 | ５−ブロモ−インジルビン |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US20160068517A1 (enExample) |
| EP (1) | EP2970310B1 (enExample) |
| JP (1) | JP6422936B2 (enExample) |
| KR (1) | KR102275112B1 (enExample) |
| CN (1) | CN105283456B (enExample) |
| AU (1) | AU2014236370C1 (enExample) |
| BR (1) | BR112015023383A2 (enExample) |
| CA (1) | CA2902914A1 (enExample) |
| EA (1) | EA035877B1 (enExample) |
| IL (1) | IL240916A0 (enExample) |
| MX (1) | MX2015013021A (enExample) |
| WO (1) | WO2014153023A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015023383A2 (pt) | 2013-03-14 | 2017-07-18 | Hope City | compostocomposição farmacêutica; e método de modulação |
| US20150259288A1 (en) | 2014-03-14 | 2015-09-17 | City Of Hope | 5-bromo-indirubins |
| CA2991052A1 (en) * | 2015-07-02 | 2017-01-05 | City Of Hope | Compounds and compositions including phosphorothioated oligodeoxynucleotide, and methods of use thereof |
| JP7005779B2 (ja) * | 2017-10-31 | 2022-02-10 | ペレメッド カンパニー リミテッド | 急性骨髄性白血病又は転移性乳癌の予防又は治療用薬剤学的組成物 |
| KR102443617B1 (ko) * | 2019-12-06 | 2022-09-16 | 광주과학기술원 | 근감소증 또는 근위축증의 예방 또는 치료용 약제학적 조성물 |
| KR102744517B1 (ko) * | 2022-02-14 | 2024-12-19 | 주식회사 펠레메드 | 신규한 헤테로비시클릭 잔기를 갖는 인디루빈 유도체 및 이의 용도 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| DK0495421T3 (da) | 1991-01-15 | 1996-12-09 | Alcon Lab Inc | Anvendelse af carragenaner i topiske ophthalmiske sammensætninger |
| US5212162A (en) | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| FR2801216A1 (fr) | 1999-11-23 | 2001-05-25 | Centre Nat Rech Scient | Utilisation de derives d'indirubine pour la fabrication de medicaments |
| US20050154046A1 (en) | 2004-01-12 | 2005-07-14 | Longgui Wang | Methods of treating an inflammatory-related disease |
| CN100569076C (zh) * | 2004-05-12 | 2009-12-16 | 拜尔作物科学有限公司 | 植物生长调节作用 |
| WO2006036892A2 (en) * | 2004-09-24 | 2006-04-06 | Sapphire Therapeutics, Inc. | Use of inhibitors of 24-hydroxylase in the treatment of cancer |
| JP5448455B2 (ja) * | 2005-12-23 | 2014-03-19 | サーントゥル ナシオナル ドゥ ラ ルシェルシュ シャーンティフィク （セ エン エール エス） | 新規３’−，７−置換インジルビンおよびそれらの適用 |
| EP2149553B1 (en) * | 2008-08-01 | 2011-10-19 | Centre National de la Recherche Scientifique | 3', 6-substituted indirubins and their biological applications |
| EP2518139A1 (en) * | 2011-04-27 | 2012-10-31 | Universitätsklinikum Jena | Use of indirubin derivatives for producing pluripotent stem cells |
| EP2733140A4 (en) | 2011-07-15 | 2014-11-26 | Univ Nihon | INDIRUBINE DERIVATIVE WITH HIGHLY SELF-ACTIVE CYTOTOXICITY FOR POOR TUMORS |
| US10435367B2 (en) * | 2013-03-14 | 2019-10-08 | City Of Hope | Indirubin derivatives, and uses thereof |
| BR112015023383A2 (pt) | 2013-03-14 | 2017-07-18 | Hope City | compostocomposição farmacêutica; e método de modulação |
| US20150259288A1 (en) | 2014-03-14 | 2015-09-17 | City Of Hope | 5-bromo-indirubins |
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2014
- 2014-03-14 BR BR112015023383A patent/BR112015023383A2/pt not_active Application Discontinuation
- 2014-03-14 CA CA2902914A patent/CA2902914A1/en not_active Abandoned
- 2014-03-14 EP EP14770647.7A patent/EP2970310B1/en active Active
- 2014-03-14 WO PCT/US2014/028730 patent/WO2014153023A1/en not_active Ceased
- 2014-03-14 MX MX2015013021A patent/MX2015013021A/es unknown
- 2014-03-14 JP JP2016502881A patent/JP6422936B2/ja not_active Expired - Fee Related
- 2014-03-14 CN CN201480021350.4A patent/CN105283456B/zh not_active Expired - Fee Related
- 2014-03-14 EA EA201591709A patent/EA035877B1/ru not_active IP Right Cessation
- 2014-03-14 AU AU2014236370A patent/AU2014236370C1/en not_active Ceased
- 2014-03-14 KR KR1020157027506A patent/KR102275112B1/ko not_active Expired - Fee Related
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2015
- 2015-08-30 IL IL240916A patent/IL240916A0/en unknown
- 2015-09-10 US US14/850,579 patent/US20160068517A1/en not_active Abandoned
-
2018
- 2018-02-15 US US15/898,151 patent/US20180170915A1/en not_active Abandoned
-
2020
- 2020-02-13 US US16/790,611 patent/US11306072B2/en active Active
-
2022
- 2022-03-09 US US17/690,323 patent/US20220274964A1/en not_active Abandoned