JP2016513076A5 - - Google Patents
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- JP2016513076A5 JP2016513076A5 JP2015552988A JP2015552988A JP2016513076A5 JP 2016513076 A5 JP2016513076 A5 JP 2016513076A5 JP 2015552988 A JP2015552988 A JP 2015552988A JP 2015552988 A JP2015552988 A JP 2015552988A JP 2016513076 A5 JP2016513076 A5 JP 2016513076A5
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- 0 *[C@@]([C@]1N2c3ccc(*)cc3OC1)OC2=O Chemical compound *[C@@]([C@]1N2c3ccc(*)cc3OC1)OC2=O 0.000 description 7
- NFIIPMYLMSQNTJ-WMZOPIPTSA-N CC1(C)OB(c(cc2)cc(OC[C@H]3[C@H](C[NH+](Cc([s]4)ccc4Cl)[O-])O4)c2N3C4=O)OC1(C)C Chemical compound CC1(C)OB(c(cc2)cc(OC[C@H]3[C@H](C[NH+](Cc([s]4)ccc4Cl)[O-])O4)c2N3C4=O)OC1(C)C NFIIPMYLMSQNTJ-WMZOPIPTSA-N 0.000 description 1
- KGPXIJYWEXCUHO-UHFFFAOYSA-N Cc1cc(N)c(N)[nH]1 Chemical compound Cc1cc(N)c(N)[nH]1 KGPXIJYWEXCUHO-UHFFFAOYSA-N 0.000 description 1
- HEHBBRXNJWHZGB-UHFFFAOYSA-N Cc1ccc(N)[nH]1 Chemical compound Cc1ccc(N)[nH]1 HEHBBRXNJWHZGB-UHFFFAOYSA-N 0.000 description 1
- XTDUKQGBGVIMCD-WPRPVWTQSA-N NC[C@@H]([C@H]1N2c(ccc(Br)c3)c3OC1)OC2=O Chemical compound NC[C@@H]([C@H]1N2c(ccc(Br)c3)c3OC1)OC2=O XTDUKQGBGVIMCD-WPRPVWTQSA-N 0.000 description 1
- HOPVBLLVGWUCLK-UHFFFAOYSA-N Nc(cc1)cc2c1[nH]c(I)c2 Chemical compound Nc(cc1)cc2c1[nH]c(I)c2 HOPVBLLVGWUCLK-UHFFFAOYSA-N 0.000 description 1
- JMOPNBCGCWAEAN-UHFFFAOYSA-N Nc1c(cc([nH]2)I)c2ccc1 Chemical compound Nc1c(cc([nH]2)I)c2ccc1 JMOPNBCGCWAEAN-UHFFFAOYSA-N 0.000 description 1
- WEFIGUGLOSYKFN-UHFFFAOYSA-N Nc1cc([nH]c(I)c2)c2cc1 Chemical compound Nc1cc([nH]c(I)c2)c2cc1 WEFIGUGLOSYKFN-UHFFFAOYSA-N 0.000 description 1
- ZEGKYPUCMUYOLK-UHFFFAOYSA-N Nc1cccc2c1[nH]c(I)c2 Chemical compound Nc1cccc2c1[nH]c(I)c2 ZEGKYPUCMUYOLK-UHFFFAOYSA-N 0.000 description 1
- ISUYQOGYJWAFTD-JQWIXIFHSA-N [O-][NH+](C[C@@H]([C@H]1N2c(ccc(Br)c3)c3OC1)OC2=O)c([s]1)ccc1Cl Chemical compound [O-][NH+](C[C@@H]([C@H]1N2c(ccc(Br)c3)c3OC1)OC2=O)c([s]1)ccc1Cl ISUYQOGYJWAFTD-JQWIXIFHSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310020040.8A CN103936763B (zh) | 2013-01-18 | 2013-01-18 | 噁唑烷酮类化合物及其制备方法和用途 |
| CN201310020040.8 | 2013-01-18 | ||
| PCT/CN2013/090833 WO2014110971A1 (zh) | 2013-01-18 | 2013-12-30 | 噁唑烷酮类化合物及其制备方法和用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016513076A JP2016513076A (ja) | 2016-05-12 |
| JP2016513076A5 true JP2016513076A5 (enExample) | 2017-10-19 |
| JP6242915B2 JP6242915B2 (ja) | 2017-12-06 |
Family
ID=51184670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015552988A Expired - Fee Related JP6242915B2 (ja) | 2013-01-18 | 2013-12-30 | オキサゾリジノン系化合物およびその製造方法と使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9382265B2 (enExample) |
| EP (1) | EP2947085B1 (enExample) |
| JP (1) | JP6242915B2 (enExample) |
| KR (1) | KR101756570B1 (enExample) |
| CN (1) | CN103936763B (enExample) |
| AU (1) | AU2013373885B2 (enExample) |
| CA (1) | CA2898550C (enExample) |
| WO (1) | WO2014110971A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015043364A1 (zh) * | 2013-09-29 | 2015-04-02 | 华北制药集团新药研究开发有限责任公司 | 作为凝血因子Xa抑制剂的苯并恶唑并恶嗪酮类化合物 |
| WO2015110024A1 (en) * | 2014-01-24 | 2015-07-30 | Sunshine Lake Pharma Co., Ltd. | Oxazolidinone compounds and their uses in pharmaceuticals |
| WO2015176677A1 (en) * | 2014-05-22 | 2015-11-26 | Sunshine Lake Pharma Co., Ltd. | Crystalline forms and amorphism of oxazolidinone compound |
| WO2015188787A1 (en) * | 2014-06-14 | 2015-12-17 | Sunshine Lake Pharma Co., Ltd. | Method for preparing oxazolidinone compound and intermediates thereof |
| CN105503903B (zh) * | 2014-09-26 | 2019-04-26 | 华北制药集团新药研究开发有限责任公司 | 苯并恶唑并恶嗪酮类化合物的制备方法及其中间体和晶型 |
| CN104610258B (zh) * | 2015-02-14 | 2016-03-30 | 佛山市赛维斯医药科技有限公司 | 一类含酰胺和甲氧苯结构的FXa抑制剂、制备方法及其用途 |
| CN104672236B (zh) * | 2015-02-14 | 2016-03-30 | 佛山市赛维斯医药科技有限公司 | 一类含双酰胺基和卤代苯结构的FXa抑制剂及其用途 |
| CN104610260B (zh) * | 2015-02-14 | 2016-03-30 | 佛山市赛维斯医药科技有限公司 | 一类含酰胺和氮杂环结构的FXa抑制剂、制备方法及其用途 |
| CN106478658A (zh) * | 2015-08-25 | 2017-03-08 | 华北制药集团新药研究开发有限责任公司 | 苯并恶唑并恶嗪酮类化合物wa1-089的晶型d及其制备方法 |
| CN106478661A (zh) * | 2015-08-25 | 2017-03-08 | 华北制药集团新药研究开发有限责任公司 | 苯并恶唑并恶嗪酮类化合物wa1-089的晶型e及其制备方法 |
| CN105348275A (zh) * | 2015-12-10 | 2016-02-24 | 中国药科大学 | 噁唑烷酮类化合物及其合成方法与医药应用 |
| CN108069983A (zh) * | 2016-11-10 | 2018-05-25 | 浙江普洛得邦制药有限公司 | 一种噁唑烷酮类化合物的晶型及其制备方法和应用 |
| CN108395442A (zh) * | 2017-02-07 | 2018-08-14 | 浙江普洛得邦制药有限公司 | 一种噁唑烷酮类化合物的晶型vii及其制备方法和应用 |
| CN108727406B (zh) | 2017-03-28 | 2021-12-07 | 北京协和制药二厂 | 含氮杂环取代的苯并噁嗪噁唑烷酮类化合物及其制备方法和用途 |
| CN109111465B (zh) * | 2017-06-22 | 2021-01-12 | 中国科学院上海药物研究所 | 噻唑烷酮螺嘧啶三酮类化合物及制备方法和用途 |
| CN108912142B (zh) * | 2018-08-08 | 2021-06-18 | 延边大学 | 吡咯并苯并恶嗪酮类化合物及其注射剂和在抗血栓中的用途 |
| CN114685529A (zh) * | 2020-12-29 | 2022-07-01 | 中国科学院上海药物研究所 | 噁唑烷酮类化合物的无定形物及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19805117A1 (de) * | 1998-02-09 | 1999-08-12 | Bayer Ag | Neue Oxazolidinone mit azolhaltigen Tricyclen |
| DE10129725A1 (de) * | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
| TWI396686B (zh) * | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
| KR20110104491A (ko) * | 2008-12-19 | 2011-09-22 | 다이이찌 산쿄 가부시키가이샤 | 활성화 혈액 응고 제 Ｘ 인자 (ＦＸａ) 저해제 |
| CN102260277B (zh) * | 2010-05-24 | 2013-07-24 | 中国科学院上海药物研究所 | 新型苯并噁嗪噁唑烷酮类化合物及其制备方法和用途 |
| CN102464658B (zh) * | 2010-11-03 | 2014-04-16 | 天津药物研究院 | 噁唑烷酮衍生物及其制备方法和用途 |
-
2013
- 2013-01-18 CN CN201310020040.8A patent/CN103936763B/zh active Active
- 2013-12-30 US US14/761,843 patent/US9382265B2/en active Active
- 2013-12-30 KR KR1020157021881A patent/KR101756570B1/ko not_active Expired - Fee Related
- 2013-12-30 EP EP13872046.1A patent/EP2947085B1/en not_active Not-in-force
- 2013-12-30 WO PCT/CN2013/090833 patent/WO2014110971A1/zh not_active Ceased
- 2013-12-30 AU AU2013373885A patent/AU2013373885B2/en not_active Ceased
- 2013-12-30 CA CA2898550A patent/CA2898550C/en active Active
- 2013-12-30 JP JP2015552988A patent/JP6242915B2/ja not_active Expired - Fee Related
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