JP2016512041A - 多重対立遺伝子の検出 - Google Patents

多重対立遺伝子の検出 Download PDF

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JP2016512041A
JP2016512041A JP2016502320A JP2016502320A JP2016512041A JP 2016512041 A JP2016512041 A JP 2016512041A JP 2016502320 A JP2016502320 A JP 2016502320A JP 2016502320 A JP2016502320 A JP 2016502320A JP 2016512041 A JP2016512041 A JP 2016512041A
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primer
fluorophore
nucleic acid
quencher
probe
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Japanese (ja)
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JP2016512041A5 (OSRAM
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ホワン，シーハイ
スウ，ホン
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アボツト・モレキユラー・インコーポレイテツド
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Publication of JP2016512041A publication Critical patent/JP2016512041A/ja
Publication of JP2016512041A5 publication Critical patent/JP2016512041A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2016502320A 2013-03-15 2014-03-14 多重対立遺伝子の検出 Pending JP2016512041A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361792202P 2013-03-15 2013-03-15
US61/792,202 2013-03-15
PCT/US2014/027048 WO2014152185A1 (en) 2013-03-15 2014-03-14 Multiplex allele detection

Publications (2)

Publication Number Publication Date
JP2016512041A true JP2016512041A (ja) 2016-04-25
JP2016512041A5 JP2016512041A5 (OSRAM) 2017-03-30

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ID=51529833

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016502320A Pending JP2016512041A (ja) 2013-03-15 2014-03-14 多重対立遺伝子の検出

Country Status (5)

Country Link
US (1) US20140274779A1 (OSRAM)
EP (1) EP2971147A4 (OSRAM)
JP (1) JP2016512041A (OSRAM)
CN (1) CN105431550A (OSRAM)
WO (1) WO2014152185A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023542408A (ja) * 2020-09-23 2023-10-06 マキュラ バイオテクノロジー カンパニー リミテッド 核酸を検出する組み合わせ、方法及びキット

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107109492B (zh) * 2014-12-22 2021-02-26 阿纳帕生物技术股份公司 用于靶核酸多重检测的双重猝灭测定
US20210108253A1 (en) * 2017-03-30 2021-04-15 Life Technologies Corporation Quantification of ngs dna by adapter sequence
CN107760764B (zh) * 2017-10-23 2023-04-07 上海阅尔基因技术有限公司 一种基于引物荧光和淬灭标记的靶核酸检测方法和试剂盒
CN109355360A (zh) * 2018-11-20 2019-02-19 元码基因科技（北京）股份有限公司 用于检测egfr突变的组合物、试剂盒和方法
CN110195099B (zh) * 2019-05-28 2021-07-13 西安交通大学 一种多靶标基因并行检测组合探针及其试剂盒的应用
US20220017948A1 (en) * 2020-06-23 2022-01-20 Genomind, Inc. Detection of specific hla alleles
CN113201533B (zh) * 2021-05-28 2023-06-20 南方医科大学 基于催化发夹自组装恒温扩增技术检测核酸的通用探针及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003500038A (ja) * 1999-05-24 2003-01-07 ザ・パブリック・ヘルス・リサーチ・インスティテュート・オブ・ザ・シティ・オブ・ニュー・ヨーク・インコーポレーテッド 高い特異性を有するプライマー、増幅法およびキット
WO2011078441A1 (en) * 2009-12-21 2011-06-30 Seegene, Inc. Tsg primer target detection
JP2013501523A (ja) * 2009-08-11 2013-01-17 レスポンス ジェネティクス，インコーポレイティド Ｂｒａｆ変異の検出に有用な方法、プライマー、プローブ、及びキット

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US20030165859A1 (en) * 2001-10-23 2003-09-04 Invitrogen Corporation Primers and methods for the detection and discrimination of nucleic acids
EP1509624A2 (en) * 2002-05-31 2005-03-02 Secretary, Department Of Atomic Energy Met/fret based method of target nucleic acid detection whereby the donor/acceptor moieties are on complementary strands
CA2587085C (en) * 2004-10-27 2017-08-08 Cepheid Closed-system multi-stage nucleic acid amplification reactions
DK2412718T3 (en) * 2009-03-26 2017-01-30 Xiamen Amoy Diagnostics Co Ltd CIRCUIT PRIMES USED BY NUCLEIC ACID AMPLIFICATION AND USE THEREOF
US8728763B2 (en) * 2009-08-11 2014-05-20 Response Genetics Methods, primers, probes and kits useful for the detection of BRAF mutations
CN102161990A (zh) * 2010-02-24 2011-08-24 北京雅康博生物科技有限公司 用于定量检测braf突变的试剂盒

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003500038A (ja) * 1999-05-24 2003-01-07 ザ・パブリック・ヘルス・リサーチ・インスティテュート・オブ・ザ・シティ・オブ・ニュー・ヨーク・インコーポレーテッド 高い特異性を有するプライマー、増幅法およびキット
JP2013501523A (ja) * 2009-08-11 2013-01-17 レスポンス ジェネティクス，インコーポレイティド Ｂｒａｆ変異の検出に有用な方法、プライマー、プローブ、及びキット
WO2011078441A1 (en) * 2009-12-21 2011-06-30 Seegene, Inc. Tsg primer target detection

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ARCH. PATHOL. LAB. MED., vol. 131, JPN6014054711, 2007, pages 1361 - 1367, ISSN: 0004042025 *
EUROPEAN UROLOGY, vol. 50, JPN6014054707, 2006, pages 1102 - 1110, ISSN: 0004042027 *
J. MOL. DIAGNOSTICS, vol. 9, no. 2, JPN6014054705, 2007, pages 178 - 183, ISSN: 0004042024 *
NEUROENDOCRINOLOGY LETTERS, vol. 28, no. 4, JPN6014054710, 2007, pages 351 - 359, ISSN: 0004042026 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023542408A (ja) * 2020-09-23 2023-10-06 マキュラ バイオテクノロジー カンパニー リミテッド 核酸を検出する組み合わせ、方法及びキット
JP7519537B2 (ja) 2020-09-23 2024-07-19 マキュラ バイオテクノロジー カンパニー リミテッド 核酸を検出する組み合わせ、方法及びキット

Also Published As

Publication number Publication date
WO2014152185A1 (en) 2014-09-25
CN105431550A (zh) 2016-03-23
EP2971147A4 (en) 2016-08-31
US20140274779A1 (en) 2014-09-18
EP2971147A1 (en) 2016-01-20

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