JP2016511230A - 治療用組成物およびｍＲＮＡトランスフェクションを含む方法 - Google Patents

治療用組成物およびｍＲＮＡトランスフェクションを含む方法 Download PDF

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JP2016511230A
JP2016511230A JP2015552801A JP2015552801A JP2016511230A JP 2016511230 A JP2016511230 A JP 2016511230A JP 2015552801 A JP2015552801 A JP 2015552801A JP 2015552801 A JP2015552801 A JP 2015552801A JP 2016511230 A JP2016511230 A JP 2016511230A
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cells
mrna
cell
polypeptide
protein
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Japanese (ja)
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マーク、シー．ハーツバーグ
カレン、ファーニー、ロス
ブレント、エス．ソレンソン
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Brent SSorenson
Karen Farnie Ross
Mark CHerzberg
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Brent SSorenson
Karen Farnie Ross
Mark CHerzberg
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2015552801A 2013-01-11 2014-01-10 治療用組成物およびｍＲＮＡトランスフェクションを含む方法 Pending JP2016511230A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361751504P 2013-01-11 2013-01-11
US61/751,504 2013-01-11
PCT/US2014/011041 WO2014110366A1 (en) 2013-01-11 2014-01-10 Therapeutic compositions and methods involving mrna transfection

Related Child Applications (1)

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JP2016218023A Division JP6473729B2 (ja) 2013-01-11 2016-11-08 治療用組成物およびｍＲＮＡトランスフェクションを含む方法

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JP2016511230A true JP2016511230A (ja) 2016-04-14

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JP2015552801A Pending JP2016511230A (ja) 2013-01-11 2014-01-10 治療用組成物およびｍＲＮＡトランスフェクションを含む方法
JP2016218023A Active JP6473729B2 (ja) 2013-01-11 2016-11-08 治療用組成物およびｍＲＮＡトランスフェクションを含む方法
JP2018190468A Active JP6956059B2 (ja) 2013-01-11 2018-10-05 治療用組成物およびｍＲＮＡトランスフェクションを含む方法
JP2020186487A Withdrawn JP2021019644A (ja) 2013-01-11 2020-11-09 治療用組成物およびｍＲＮＡトランスフェクションを含む方法

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JP2018190468A Active JP6956059B2 (ja) 2013-01-11 2018-10-05 治療用組成物およびｍＲＮＡトランスフェクションを含む方法
JP2020186487A Withdrawn JP2021019644A (ja) 2013-01-11 2020-11-09 治療用組成物およびｍＲＮＡトランスフェクションを含む方法

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US (3) US20150344537A1 (enExample)
EP (2) EP2943226B1 (enExample)
JP (4) JP2016511230A (enExample)
KR (2) KR102056511B1 (enExample)
CN (1) CN105473163A (enExample)
AU (1) AU2014205298B2 (enExample)
CA (2) CA2901409C (enExample)
ES (1) ES2738315T3 (enExample)
IL (2) IL239898B (enExample)
NZ (1) NZ710495A (enExample)
PL (1) PL2943226T3 (enExample)
SG (2) SG11201505431XA (enExample)
WO (1) WO2014110366A1 (enExample)

Cited By (1)

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JP2021521420A (ja) * 2018-04-12 2021-08-26 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 軽度又は進行性歯周病の診断

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US20150344537A1 (en) * 2013-01-11 2015-12-03 Mark C. Herzberg Non-Transgene Transfection for Therapeutic Purposes
EP3534931B1 (en) 2016-11-07 2023-01-04 Westfälische Wilhelms-Universität Münster S100a8/s100a9-induced immunotolerance in newborn subjects
CN107841508A (zh) * 2017-11-29 2018-03-27 重庆市中医院 含抑铁素重组减毒沙门杆菌及构建方法、表达或递送载体
EP3553523A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Diagnostics of mild or advanced periodontitis
JP6891157B2 (ja) * 2018-11-15 2021-06-18 正生 池本 機能性ペプチド、それを用いた大腸炎用医薬およびデリバリー剤
CN114561381A (zh) * 2022-03-14 2022-05-31 桂林医学院 免疫mRNA及其制备方法和应用

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AU7725500A (en) * 1999-09-30 2001-04-30 National Jewish Medical And Research Center Method for inhibition of pathogenic microorganisms
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DE10121254A1 (de) * 2001-04-30 2002-11-07 Switch Biotech Ag MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021521420A (ja) * 2018-04-12 2021-08-26 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 軽度又は進行性歯周病の診断
JP7391035B2 (ja) 2018-04-12 2023-12-04 コーニンクレッカ フィリップス エヌ ヴェ 軽度又は進行性歯周病の診断

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Publication number Publication date
US20240166701A1 (en) 2024-05-23
NZ710495A (en) 2019-10-25
PL2943226T3 (pl) 2019-09-30
AU2014205298A1 (en) 2015-08-13
US12448421B2 (en) 2025-10-21
JP6473729B2 (ja) 2019-02-20
EP3501551C0 (en) 2023-06-07
KR20180026811A (ko) 2018-03-13
KR102119985B1 (ko) 2020-06-05
CA3152721A1 (en) 2014-07-17
WO2014110366A1 (en) 2014-07-17
CA2901409C (en) 2022-06-07
JP2019031521A (ja) 2019-02-28
EP3501551A1 (en) 2019-06-26
EP2943226B1 (en) 2019-03-13
IL262252B (en) 2020-06-30
IL239898A0 (en) 2015-08-31
IL239898B (en) 2018-10-31
JP2021019644A (ja) 2021-02-18
SG11201505431XA (en) 2015-08-28
US20150344537A1 (en) 2015-12-03
EP3501551B1 (en) 2023-06-07
CN105473163A (zh) 2016-04-06
JP6956059B2 (ja) 2021-10-27
KR20160031999A (ko) 2016-03-23
IL262252A (en) 2018-11-29
SG10201603946PA (en) 2016-07-28
EP2943226A4 (en) 2016-11-23
US11912744B2 (en) 2024-02-27
US20200231640A1 (en) 2020-07-23
KR102056511B1 (ko) 2019-12-16
EP2943226A1 (en) 2015-11-18
ES2738315T3 (es) 2020-01-21
JP2017052781A (ja) 2017-03-16
CA2901409A1 (en) 2014-07-17
AU2014205298B2 (en) 2018-11-01

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