|
US6426334B1
(en)
|
1997-04-30 |
2002-07-30 |
Hybridon, Inc. |
Oligonucleotide mediated specific cytokine induction and reduction of tumor growth in a mammal
|
|
AU9475001A
(en)
*
|
2000-09-26 |
2002-04-08 |
Hybridon Inc |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
|
|
US7176296B2
(en)
*
|
2001-04-30 |
2007-02-13 |
Idera Pharmaceuticals, Inc. |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
|
|
US7105495B2
(en)
*
|
2001-04-30 |
2006-09-12 |
Idera Pharmaceuticals, Inc. |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
|
|
US7276489B2
(en)
*
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
|
WO2003035836A2
(en)
*
|
2001-10-24 |
2003-05-01 |
Hybridon Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
|
|
AU2004206820B2
(en)
*
|
2003-01-16 |
2010-06-10 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides
|
|
US7354907B2
(en)
*
|
2003-02-07 |
2008-04-08 |
Idera Pharmaceuticals, Inc. |
Short immunomodulatory oligonucleotides
|
|
MXPA05013658A
(es)
*
|
2003-06-11 |
2006-03-02 |
Hybridon Inc |
Oligonucleotidos inmunomoduladores estabilizados.
|
|
MXPA06000619A
(es)
*
|
2003-07-15 |
2006-04-11 |
Hybridon Inc |
Estimulacion sinergistica del sistema inmune usando oligonucleotidos inmunoestimuladores y/o compuestos inmunomeros en conjunto con citocinas y/o agentes quimioterapeuticos o terapia de radiacion.
|
|
US20050239733A1
(en)
|
2003-10-31 |
2005-10-27 |
Coley Pharmaceutical Gmbh |
Sequence requirements for inhibitory oligonucleotides
|
|
US20060014713A1
(en)
*
|
2004-06-15 |
2006-01-19 |
Hybridon, Inc. |
Immunostimulatory oligonucleotide multimers
|
|
US7427405B2
(en)
*
|
2004-06-15 |
2008-09-23 |
Idera Pharmaceuticals, Inc. |
Immunostimulatory oligonucleotide multimers
|
|
US8399423B2
(en)
|
2005-10-12 |
2013-03-19 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
US8426375B2
(en)
|
2005-10-12 |
2013-04-23 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
US8383598B2
(en)
|
2005-10-12 |
2013-02-26 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
ES2544877T3
(es)
*
|
2005-10-12 |
2015-09-04 |
Idera Pharmaceuticals |
Compuestos oligonucleótidos inmuno reguladores (IRO) para modular la respuesta inmune basada en receptor semejante a Toll
|
|
US7470674B2
(en)
*
|
2005-11-07 |
2008-12-30 |
Idera Pharmaceuticals, Inc. |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides
|
|
US7776834B2
(en)
*
|
2005-11-07 |
2010-08-17 |
Idera Pharmaceuticals, Inc. |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides
|
|
US7709317B2
(en)
*
|
2005-11-14 |
2010-05-04 |
International Business Machines Corporation |
Method to increase strain enhancement with spacerless FET and dual liner process
|
|
US7786089B2
(en)
*
|
2005-12-20 |
2010-08-31 |
Idera Pharmaceuticals, Inc. |
Immunostimulatory activity of immune modulatory oligonucleotides (IMO™) containing different lengths of palindromic segments
|
|
EP2021008B1
(en)
*
|
2006-04-07 |
2015-12-02 |
Idera Pharmaceuticals, Inc. |
Stabilized immune modulatory rna (simra) compounds for tlr7 and tlr8
|
|
US8377898B2
(en)
|
2006-10-12 |
2013-02-19 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
|
|
MX2009006230A
(es)
*
|
2006-12-12 |
2009-06-22 |
Idera Pharmaceuticals Inc |
Agonistas sinteticos de receptores de tipo toll 9.
|
|
US8713253B1
(en)
*
|
2007-06-18 |
2014-04-29 |
Guidance-Tableau, Llc |
Modular storage system
|
|
CA2692161C
(en)
*
|
2007-07-09 |
2015-09-29 |
Idera Pharmaceuticals, Inc. |
Stabilized immune modulatory rna (simra) compounds
|
|
KR20100053598A
(ko)
*
|
2007-08-01 |
2010-05-20 |
이데라 파마슈티칼즈, 인코포레이티드 |
Tlr9의 신규한 합성 효능제
|
|
MX2010001785A
(es)
*
|
2007-08-15 |
2010-03-10 |
Idera Pharmaceuticals Inc |
Moduladores de receptores tipo larga distancia.
|
|
WO2009154609A1
(en)
*
|
2008-06-17 |
2009-12-23 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response
|
|
AU2009302468A1
(en)
|
2008-10-06 |
2010-04-15 |
Idera Pharmaceuticals, Inc. |
Use of inhibitors of toll-like receptors in the prevention and treatment of hypercholesterolemia and hyperlipidemia and diseases related thereto
|
|
US8987221B2
(en)
*
|
2009-06-01 |
2015-03-24 |
Idera Pharmaceuticals, Inc. |
Potentiation of autoimmune and inflammatory disease treatments by immune regulatory oligonucleotide (IRO) antagonists of TLR7 and TLR9
|
|
WO2011041311A2
(en)
|
2009-09-29 |
2011-04-07 |
Yale University |
Compositions and methods for inhibiting inflammation from and rejection of biomaterials and other methods
|
|
CN103153346A
(zh)
|
2010-06-16 |
2013-06-12 |
戴纳瓦克斯技术公司 |
使用tlr7和/或tlr9抑制剂的治疗方法
|
|
KR101985382B1
(ko)
*
|
2010-11-19 |
2019-06-03 |
이데라 파마슈티칼즈, 인코포레이티드 |
톨-유사 수용체 기반 면역 반응을 조절하기 위한 면역 조절 올리고뉴클레오타이드(iro) 화합물
|
|
KR102052215B1
(ko)
*
|
2011-06-01 |
2019-12-04 |
야누스 바이오테라퓨틱스, 인크. |
신규한 면역 시스템 조절제
|
|
WO2013036829A1
(en)
*
|
2011-09-09 |
2013-03-14 |
Genentech, Inc |
Treatment of th17 mediated inflammatory diseases
|
|
US9603800B2
(en)
*
|
2012-04-12 |
2017-03-28 |
Yale University |
Methods of treating inflammatory and autoimmune diseases and disorders using nanolipogels
|
|
KR101898177B1
(ko)
*
|
2013-01-08 |
2018-09-12 |
이데라 파마슈티칼즈, 인코포레이티드 |
톨-유사 수용체 기반 면역 반응을 조절하기 위한 면역 조절 올리고누클레오티드 (iro) 화합물
|
|
EP3005607B1
(en)
*
|
2013-05-30 |
2020-01-08 |
Intel Corporation |
Adaptive authentication systems and methods
|
|
US9688993B2
(en)
*
|
2015-02-13 |
2017-06-27 |
Idera Pharmaceuticals, Inc. |
Toll-like receptor 9 antagonist and methods of use thereof
|