JP2015505843A5 - - Google Patents

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Publication number
JP2015505843A5
JP2015505843A5 JP2014546255A JP2014546255A JP2015505843A5 JP 2015505843 A5 JP2015505843 A5 JP 2015505843A5 JP 2014546255 A JP2014546255 A JP 2014546255A JP 2014546255 A JP2014546255 A JP 2014546255A JP 2015505843 A5 JP2015505843 A5 JP 2015505843A5
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JP
Japan
Prior art keywords
seq
cancer
biologically active
pharmaceutical composition
fusion protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014546255A
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English (en)
Japanese (ja)
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JP2015505843A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/CA2012/050899 external-priority patent/WO2013086636A1/en
Publication of JP2015505843A publication Critical patent/JP2015505843A/ja
Publication of JP2015505843A5 publication Critical patent/JP2015505843A5/ja
Pending legal-status Critical Current

Links

JP2014546255A 2011-12-15 2012-12-14 可溶性IGFレセプターFc融合タンパク質およびその使用 Pending JP2015505843A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161576034P 2011-12-15 2011-12-15
US61/576,034 2011-12-15
PCT/CA2012/050899 WO2013086636A1 (en) 2011-12-15 2012-12-14 Soluble igf receptor fc fusion proteins and uses thereof

Publications (2)

Publication Number Publication Date
JP2015505843A JP2015505843A (ja) 2015-02-26
JP2015505843A5 true JP2015505843A5 (https=) 2016-02-04

Family

ID=48611766

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014546255A Pending JP2015505843A (ja) 2011-12-15 2012-12-14 可溶性IGFレセプターFc融合タンパク質およびその使用

Country Status (9)

Country Link
US (1) US10538575B2 (https=)
EP (1) EP2791338B1 (https=)
JP (1) JP2015505843A (https=)
KR (1) KR20150031217A (https=)
CN (1) CN104066845A (https=)
BR (1) BR112014014418A2 (https=)
CA (1) CA2858389A1 (https=)
HK (1) HK1202587A1 (https=)
WO (1) WO2013086636A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
KR102654033B1 (ko) * 2014-12-08 2024-04-02 1글로브 바이오메디칼 씨오., 엘티디. 가용성 유니버셜 adcc 증강 합성 융합 유전자 및 펩티드 기술 및 그 용도
WO2016193497A1 (en) * 2015-06-04 2016-12-08 Ospedale San Raffaele Srl Inhibitor of igfbp3/tmem219 axis and diabetes
CN107921094B (zh) * 2015-06-04 2022-03-01 圣拉斐尔医院有限公司 Igfbp3及其用途
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
JP7031934B2 (ja) 2016-05-11 2022-03-08 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックス
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
WO2017194592A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of storing a separation matrix
US10513537B2 (en) 2016-05-11 2019-12-24 Ge Healthcare Bioprocess R&D Ab Separation matrix
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
WO2017194593A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
US12448411B2 (en) 2016-09-30 2025-10-21 Cytiva Bioprocess R&D Ab Separation method
CN106520806B (zh) * 2016-11-03 2018-06-19 宜明细胞生物科技有限公司 一种重组car基因及其载体、car-t细胞和应用
EP3632929A1 (en) 2018-10-02 2020-04-08 Ospedale San Raffaele S.r.l. Antibodies and uses thereof
CN113092392B (zh) * 2021-03-05 2022-11-08 苏州西山中科药物研究开发有限公司 一种检测猴血清中靶向可溶性蛋白的单克隆抗体药物总浓度的通用型方法
CN119708266B (zh) * 2025-02-26 2025-06-06 首玺(广州)医疗科技有限责任公司 一种胰岛素样生长因子-1连接多肽及其在子宫内膜损伤修复中的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6084085A (en) 1995-11-14 2000-07-04 Thomas Jefferson University Inducing resistance to tumor growth with soluble IGF-1 receptor
ES2305886T3 (es) * 2003-12-30 2008-11-01 Merck Patent Gmbh Proteinas de fusion de il-7 con porciones de anticuerpo, su preparacion y su empleo.
MY146381A (en) * 2004-12-22 2012-08-15 Amgen Inc Compositions and methods relating relating to anti-igf-1 receptor antibodies
WO2007021807A1 (en) * 2005-08-12 2007-02-22 Schering Corporation Mcp1 fusions
TW200722436A (en) * 2005-10-21 2007-06-16 Hoffmann La Roche A peptide-immunoglobulin-conjugate
GB0702888D0 (en) * 2007-02-14 2007-03-28 Glaxo Group Ltd Novel Antibodies
JP2010518140A (ja) * 2007-02-14 2010-05-27 グラクソ グループ リミテッド Igf−1rに対する新規抗体
AU2008223541B2 (en) * 2007-03-02 2012-04-05 Amgen Inc. Methods and compositions for treating tumor diseases
CA2694055A1 (en) * 2007-08-01 2009-02-05 Glaxo Group Limited Novel antibodies
JP2011526792A (ja) 2008-07-02 2011-10-20 エマージェント プロダクト デベロップメント シアトル, エルエルシー TNF−αアンタゴニスト多重標的結合性タンパク質
NZ590667A (en) * 2008-07-02 2013-01-25 Emergent Product Dev Seattle Tgf-b antagonist multi-target binding proteins
JP2011529452A (ja) * 2008-07-29 2011-12-08 ザ・ロイヤル・インスティテューション・フォア・ザ・アドバンスメント・オブ・ラーニング/マクギル・ユニヴァーシティ 抗血管新生薬としての可溶性igf受容体
DK2352763T4 (da) * 2008-10-01 2022-10-17 Amgen Res Munich Gmbh Bispecifikke enkeltkædede antistoffer med specificitet for højmolekylære målantigener
WO2010136480A1 (en) * 2009-05-28 2010-12-02 Glaxo Group Limited Antigen-binding proteins

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