JP2016508726A - 組み合わせた遺伝的および化学的操作によるフォワードプログラミングを介した肝細胞の産生 - Google Patents

組み合わせた遺伝的および化学的操作によるフォワードプログラミングを介した肝細胞の産生 Download PDF

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JP2016508726A
JP2016508726A JP2015558982A JP2015558982A JP2016508726A JP 2016508726 A JP2016508726 A JP 2016508726A JP 2015558982 A JP2015558982 A JP 2015558982A JP 2015558982 A JP2015558982 A JP 2015558982A JP 2016508726 A JP2016508726 A JP 2016508726A
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cells
cell
hepatocytes
stem cells
hepatocyte
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ジュンイン ユー，
ジュンイン ユー，
シン ザン，
シン ザン，
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セルラー ダイナミクス インターナショナル， インコーポレイテッド
セルラー ダイナミクス インターナショナル， インコーポレイテッド
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JP2015558982A 2013-02-22 2014-02-21 組み合わせた遺伝的および化学的操作によるフォワードプログラミングを介した肝細胞の産生 Pending JP2016508726A (ja)

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US201361768301P 2013-02-22 2013-02-22
US61/768,301 2013-02-22
PCT/US2014/017588 WO2014130770A1 (en) 2013-02-22 2014-02-21 Hepatocyte production via forward programming by combined genetic and chemical engineering

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JP2016508726A true JP2016508726A (ja) 2016-03-24
JP2016508726A5 JP2016508726A5 (enExample) 2016-12-01

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US (1) US20140242595A1 (enExample)
EP (1) EP2958992A1 (enExample)
JP (1) JP2016508726A (enExample)
CN (1) CN105229144A (enExample)
AU (1) AU2014218807A1 (enExample)
CA (1) CA2901747A1 (enExample)
IL (1) IL240747A0 (enExample)
WO (1) WO2014130770A1 (enExample)

Cited By (3)

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JP2018518941A (ja) * 2016-04-15 2018-07-19 サクラ ファインテック ユー．エス．エー．， インコーポレイテッド 高温時の蒸発を低減する方法
JP2019535272A (ja) * 2016-11-16 2019-12-12 アリール バイオテクノロジー アンド ファーマシューティカルズ， インコーポレイテッド Ｒｎａでの幹細胞分化による肝細胞の誘導
JP2024012479A (ja) * 2018-02-05 2024-01-30 オーデンツ セラピューティクス，インコーポレーテッド 転写調節要素及びその使用

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US11241505B2 (en) 2015-02-13 2022-02-08 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof
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WO2017043647A1 (ja) * 2015-09-11 2017-03-16 国立研究開発法人理化学研究所 転写因子結合部位特異的なｄｎａ脱メチル化方法
EP3365429B1 (en) 2015-10-19 2020-03-11 FUJIFILM Cellular Dynamics, Inc. Production of virus-receptive pluripotent stem cell (psc)-derived hepatocytes
EP3397753B1 (en) 2015-12-30 2021-10-27 FUJIFILM Cellular Dynamics, Inc. Microtissue formation using stem cell-derived human hepatocytes
IL264439B2 (en) 2016-08-17 2024-08-01 Factor Bioscience Inc non-viral, cell-free composition comprising a synthetic messenger RNA (MRNA) encoding a gene-editing protein for use in treating cancer, and a synthetic RNA encoding a gene-editing protein for use in treatment
CN108060120B (zh) * 2016-11-07 2022-11-04 云南济慈再生医学研究院有限公司 用于分化的细胞重编程的小分子化合物组合、试剂盒及应用
EP3692141A1 (en) * 2017-10-03 2020-08-12 Children's Hospital and Clinics of Minnesota Vectors and methods of use
CN110055217B (zh) * 2019-01-29 2021-03-30 中国人民解放军军事科学院军事医学研究院 获得巨核细胞及血小板的方法
CA3145425A1 (en) 2019-07-03 2021-01-07 Factor Bioscience Inc. Cationic lipids and uses thereof
US10501404B1 (en) 2019-07-30 2019-12-10 Factor Bioscience Inc. Cationic lipids and transfection methods
CN111004770B (zh) * 2019-09-25 2022-08-23 中国人民解放军军事科学院军事医学研究院 功能性肝细胞诱导方法及其专用三维诱导培养基和应用
EP4061400A4 (en) 2019-11-20 2024-01-10 Cornell University GENERATION OF GLOMERULAR-SPECIFIC KIDNEY ENDOTHELIAL CELLS AND METHOD OF USE
CN114480253B (zh) * 2022-01-30 2023-02-28 深圳市三启生物技术有限公司 多能干细胞定向诱导分化为肝细胞的培养基及培养方法和用途
CN114480495A (zh) * 2022-02-14 2022-05-13 深圳市三启生物技术有限公司 一种alb融合蛋白的表达方法及其应用
CN119895028A (zh) * 2022-06-15 2025-04-25 Gc治疗公司 用于干细胞分化的方法和组合物
CN122477276A (zh) * 2023-10-31 2026-07-28 儿童医疗中心公司 内皮细胞因子及其方法

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