JP2016508036A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016508036A5 JP2016508036A5 JP2015550089A JP2015550089A JP2016508036A5 JP 2016508036 A5 JP2016508036 A5 JP 2016508036A5 JP 2015550089 A JP2015550089 A JP 2015550089A JP 2015550089 A JP2015550089 A JP 2015550089A JP 2016508036 A5 JP2016508036 A5 JP 2016508036A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- fragment
- variant
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12425208.1 | 2012-12-28 | ||
| EP12425208.1A EP2749569A1 (en) | 2012-12-28 | 2012-12-28 | Variant of BPIFB4 protein |
| PCT/EP2013/078076 WO2014102343A1 (en) | 2012-12-28 | 2013-12-27 | Variant of bpifb4 protein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016508036A JP2016508036A (ja) | 2016-03-17 |
| JP2016508036A5 true JP2016508036A5 (enExample) | 2017-02-09 |
| JP6461810B2 JP6461810B2 (ja) | 2019-01-30 |
Family
ID=47715813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015550089A Active JP6461810B2 (ja) | 2012-12-28 | 2013-12-27 | Ｂｐｉｆｂ４タンパク質の変異体 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20150344536A1 (enExample) |
| EP (4) | EP2749569A1 (enExample) |
| JP (1) | JP6461810B2 (enExample) |
| CN (1) | CN104955836B (enExample) |
| AU (1) | AU2013369292B2 (enExample) |
| CA (1) | CA2896166A1 (enExample) |
| ES (2) | ES2951691T3 (enExample) |
| WO (1) | WO2014102343A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2749569A1 (en) * | 2012-12-28 | 2014-07-02 | Annibale Alessandro Puca | Variant of BPIFB4 protein |
| CN104558144B (zh) * | 2014-12-30 | 2017-08-08 | 深圳市第二人民医院 | 鼠Bpifb5突变体、蛋白及其应用 |
| JP2020531047A (ja) * | 2017-08-16 | 2020-11-05 | エッレジヴ１・ソチエタ・ア・レスポンサビリタ・リミタータ | 神経疾患及び神経損傷における使用のためのｂｐｉｆｂ４タンパク質のｖｔｆｔアイソフォーム |
| EP4434534A1 (en) | 2023-03-22 | 2024-09-25 | ADvantage Therapeutics, Inc. | Klotho mrna |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL87737A (en) * | 1987-09-11 | 1993-08-18 | Genentech Inc | Method for culturing polypeptide factor dependent vertebrate recombinant cells |
| US6391311B1 (en) * | 1998-03-17 | 2002-05-21 | Genentech, Inc. | Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1 |
| CA2406195A1 (en) * | 2000-04-18 | 2001-10-25 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Lipid binding protein 4 |
| JP2004532006A (ja) | 2001-02-08 | 2004-10-21 | インサイト・ゲノミックス・インコーポレイテッド | 細胞内シグナル伝達分子 |
| DK2573170T3 (en) | 2001-12-17 | 2018-04-09 | Univ Pennsylvania | Sequences of adeno-associated virus (AAV) serotype 9, vectors containing them, and their use |
| EP2345731B1 (en) | 2003-09-30 | 2015-10-21 | The Trustees of the University of Pennsylvania | Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof |
| WO2006022619A2 (en) * | 2004-07-22 | 2006-03-02 | Sequenom, Inc. | Methods for identifying risk of type ii diabetes and treatments thereof |
| EP2027296A4 (en) * | 2006-05-31 | 2010-06-02 | Philadelphia Children Hospital | COMPOSITIONS AND METHODS FOR DETECTING AND MODULATING T-CELL-IMMUNE ATTACHMENTS TO VIRAL VECTORS USED IN GENDER THERAPY |
| WO2008073915A2 (en) | 2006-12-08 | 2008-06-19 | Asuragen, Inc. | Micrornas differentially expressed in leukemia and uses thereof |
| EP2019143A1 (en) | 2007-07-23 | 2009-01-28 | Genethon | CNS gene delivery using peripheral administration of AAV vectors |
| WO2010071832A1 (en) | 2008-12-19 | 2010-06-24 | Nationwide Children's Hospital | Delivery of polynucleotides across the blood brain barrier using recombinant aav9 |
| JP2011231022A (ja) * | 2010-04-23 | 2011-11-17 | Ajinomoto Co Inc | イミダゾロン誘導体 |
| TR201908020T4 (tr) | 2011-02-17 | 2019-06-21 | Univ Pennsylvania | Doku özgüllüğünü değiştirmek ve aav9-aracılı gen transferini geliştirmek için bileşimler ve yöntemler. |
| WO2013151665A2 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
| EP2749569A1 (en) * | 2012-12-28 | 2014-07-02 | Annibale Alessandro Puca | Variant of BPIFB4 protein |
-
2012
- 2012-12-28 EP EP12425208.1A patent/EP2749569A1/en not_active Withdrawn
-
2013
- 2013-12-27 EP EP13814575.0A patent/EP2938629B1/en active Active
- 2013-12-27 CA CA2896166A patent/CA2896166A1/en active Pending
- 2013-12-27 US US14/655,651 patent/US20150344536A1/en not_active Abandoned
- 2013-12-27 CN CN201380068475.8A patent/CN104955836B/zh active Active
- 2013-12-27 JP JP2015550089A patent/JP6461810B2/ja active Active
- 2013-12-27 EP EP23177551.1A patent/EP4253405A3/en active Pending
- 2013-12-27 WO PCT/EP2013/078076 patent/WO2014102343A1/en not_active Ceased
- 2013-12-27 ES ES19167663T patent/ES2951691T3/es active Active
- 2013-12-27 ES ES13814575T patent/ES2731126T3/es active Active
- 2013-12-27 AU AU2013369292A patent/AU2013369292B2/en active Active
- 2013-12-27 EP EP19167663.4A patent/EP3560952B9/en active Active
-
2019
- 2019-07-15 US US16/511,051 patent/US11208447B2/en active Active
-
2021
- 2021-11-12 US US17/525,531 patent/US11891421B2/en active Active
-
2023
- 2023-12-19 US US18/545,302 patent/US12486308B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230210887A1 (en) | Nucleic acid molecules for reduction of papd5 or papd7 mrna for treating hepatitis b infection | |
| EP2281040B1 (en) | Lyophilized dna formulations for enhanced expression of plasmid dna | |
| JP2018536405A (ja) | 心臓状態および他の病態の処置のための複数の生物学的に活性なポリペプチドを単一のベクターから発現させるための組成物および方法 | |
| JP2016508036A5 (enExample) | ||
| JP2016518325A5 (enExample) | ||
| US20240271139A1 (en) | Engineered Guide RNAs and Polynucleotides | |
| JP2006502702A5 (enExample) | ||
| CN116785309A (zh) | 环状rna在制备用于预防和/或治疗缺血性卒中药物中的应用 | |
| JP6461810B2 (ja) | Ｂｐｉｆｂ４タンパク質の変異体 | |
| CN104288781B (zh) | miR‑329在制备预防和/或治疗缺血性眼部疾病的药物中的应用 | |
| CN104288764B (zh) | Cd146作为预防和/或治疗缺血性眼部疾病的药物靶点的应用 | |
| JP2025510946A5 (enExample) | ||
| CN113846098B (zh) | 一种小rna及其在心血管疾病治疗中的用途 | |
| KR102114880B1 (ko) | 코돈 최적화된 TIF1γ 폴리뉴클레오티드를 포함하는 재조합 벡터 및 이의 용도 | |
| US12540330B2 (en) | Stem-loop compositions and methods for inhibiting vascular endothelial growth factor | |
| EP4301863A1 (en) | Compositions and methods for the treatment of hemophilia | |
| JPWO2009013794A1 (ja) | インスリン分泌誘導剤及び膵臓β細胞増加促進剤 | |
| WO2003091271A1 (en) | Alternatively spliced nucleic acid molecules | |
| CN103601808A (zh) | 新型钠肽、制备方法及其在制备基因工程药物中的应用 | |
| EP4093427B1 (en) | Pro-anp for use in the treatment of cardiac remodelling | |
| JPWO2004096277A1 (ja) | 眼内血管新生疾患の予防又は治療剤 | |
| JPWO2018088464A1 (ja) | 脳梗塞の治療薬 | |
| Seneviratne et al. | 181 M1 MACROPHAGES AND IRF5 EXACERBATE ATHEROSCLEROTIC DISEASE | |
| CN120695213A (zh) | 用于治疗肺气肿的mRNA组合产品及其应用 | |
| AU2023272839A1 (en) | Compositions and methods for treating a cardiac disease |