JP2016508036A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016508036A5 JP2016508036A5 JP2015550089A JP2015550089A JP2016508036A5 JP 2016508036 A5 JP2016508036 A5 JP 2016508036A5 JP 2015550089 A JP2015550089 A JP 2015550089A JP 2015550089 A JP2015550089 A JP 2015550089A JP 2016508036 A5 JP2016508036 A5 JP 2016508036A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- fragment
- variant
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12425208.1A EP2749569A1 (en) | 2012-12-28 | 2012-12-28 | Variant of BPIFB4 protein |
| EP12425208.1 | 2012-12-28 | ||
| PCT/EP2013/078076 WO2014102343A1 (en) | 2012-12-28 | 2013-12-27 | Variant of bpifb4 protein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016508036A JP2016508036A (ja) | 2016-03-17 |
| JP2016508036A5 true JP2016508036A5 (enExample) | 2017-02-09 |
| JP6461810B2 JP6461810B2 (ja) | 2019-01-30 |
Family
ID=47715813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015550089A Active JP6461810B2 (ja) | 2012-12-28 | 2013-12-27 | Ｂｐｉｆｂ４タンパク質の変異体 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20150344536A1 (enExample) |
| EP (4) | EP2749569A1 (enExample) |
| JP (1) | JP6461810B2 (enExample) |
| CN (1) | CN104955836B (enExample) |
| AU (1) | AU2013369292B2 (enExample) |
| CA (1) | CA2896166A1 (enExample) |
| ES (2) | ES2731126T3 (enExample) |
| WO (1) | WO2014102343A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2749569A1 (en) * | 2012-12-28 | 2014-07-02 | Annibale Alessandro Puca | Variant of BPIFB4 protein |
| CN104558144B (zh) * | 2014-12-30 | 2017-08-08 | 深圳市第二人民医院 | 鼠Bpifb5突变体、蛋白及其应用 |
| ES2970198T3 (es) | 2017-08-16 | 2024-05-27 | Lgv1 S R L | Isoforma VTFT de una proteína BPIFB4 para uso en enfermedades y lesiones neuronales |
| EP4434534A1 (en) | 2023-03-22 | 2024-09-25 | ADvantage Therapeutics, Inc. | Klotho mrna |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL87737A (en) * | 1987-09-11 | 1993-08-18 | Genentech Inc | Method for culturing polypeptide factor dependent vertebrate recombinant cells |
| US6391311B1 (en) * | 1998-03-17 | 2002-05-21 | Genentech, Inc. | Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1 |
| EP1274842A2 (en) * | 2000-04-18 | 2003-01-15 | MERCK PATENT GmbH | Lipid binding protein 4 |
| WO2002063008A2 (en) | 2001-02-08 | 2002-08-15 | Incyte Genomics, Inc. | Intracellular signaling molecules |
| EP2573170B1 (en) | 2001-12-17 | 2017-12-20 | The Trustees Of The University Of Pennsylvania | Adeno-associated virus (AAV) serotype 9 sequences, vectors containing same, and uses therefor |
| ES2874298T3 (es) | 2003-09-30 | 2021-11-04 | Univ Pennsylvania | Clados de virus adenoasociados (AAV), secuencias, vectores que contienen el mismo, y usos de los mismos |
| WO2006022619A2 (en) * | 2004-07-22 | 2006-03-02 | Sequenom, Inc. | Methods for identifying risk of type ii diabetes and treatments thereof |
| CA2653600A1 (en) * | 2006-05-31 | 2007-12-06 | The Children's Hospital Of Philadelphia | Compositions and methods for detection and modulation of t cell mediated immune responses against viral vectors utilized for gene therapy |
| WO2008073915A2 (en) | 2006-12-08 | 2008-06-19 | Asuragen, Inc. | Micrornas differentially expressed in leukemia and uses thereof |
| EP2019143A1 (en) | 2007-07-23 | 2009-01-28 | Genethon | CNS gene delivery using peripheral administration of AAV vectors |
| WO2010071832A1 (en) | 2008-12-19 | 2010-06-24 | Nationwide Children's Hospital | Delivery of polynucleotides across the blood brain barrier using recombinant aav9 |
| JP2011231022A (ja) * | 2010-04-23 | 2011-11-17 | Ajinomoto Co Inc | イミダゾロン誘導体 |
| SG10201601110VA (en) | 2011-02-17 | 2016-03-30 | Univ Pennsylvania | Compositions and methods for altering tissue specificity and improving aav9-mediated gene transfer |
| AU2013243954A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| EP2749569A1 (en) * | 2012-12-28 | 2014-07-02 | Annibale Alessandro Puca | Variant of BPIFB4 protein |
-
2012
- 2012-12-28 EP EP12425208.1A patent/EP2749569A1/en not_active Withdrawn
-
2013
- 2013-12-27 WO PCT/EP2013/078076 patent/WO2014102343A1/en not_active Ceased
- 2013-12-27 CN CN201380068475.8A patent/CN104955836B/zh active Active
- 2013-12-27 EP EP13814575.0A patent/EP2938629B1/en active Active
- 2013-12-27 ES ES13814575T patent/ES2731126T3/es active Active
- 2013-12-27 ES ES19167663T patent/ES2951691T3/es active Active
- 2013-12-27 EP EP23177551.1A patent/EP4253405A3/en active Pending
- 2013-12-27 JP JP2015550089A patent/JP6461810B2/ja active Active
- 2013-12-27 CA CA2896166A patent/CA2896166A1/en active Pending
- 2013-12-27 US US14/655,651 patent/US20150344536A1/en not_active Abandoned
- 2013-12-27 EP EP19167663.4A patent/EP3560952B9/en active Active
- 2013-12-27 AU AU2013369292A patent/AU2013369292B2/en active Active
-
2019
- 2019-07-15 US US16/511,051 patent/US11208447B2/en active Active
-
2021
- 2021-11-12 US US17/525,531 patent/US11891421B2/en active Active
-
2023
- 2023-12-19 US US18/545,302 patent/US12486308B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230210887A1 (en) | Nucleic acid molecules for reduction of papd5 or papd7 mrna for treating hepatitis b infection | |
| EP2281040B1 (en) | Lyophilized dna formulations for enhanced expression of plasmid dna | |
| JP2014512808A5 (enExample) | ||
| RU2008136655A (ru) | Гибридные белки рецептора vegf, их фармацевтические композиции и терапевтическое применение при заболеваниях глаз | |
| JP2018536405A (ja) | 心臓状態および他の病態の処置のための複数の生物学的に活性なポリペプチドを単一のベクターから発現させるための組成物および方法 | |
| JP2016508036A5 (enExample) | ||
| JP2016518325A5 (enExample) | ||
| JP2006502702A5 (enExample) | ||
| CN116785309A (zh) | 环状rna在制备用于预防和/或治疗缺血性卒中药物中的应用 | |
| US20240271139A1 (en) | Engineered Guide RNAs and Polynucleotides | |
| US10428330B2 (en) | Stem-loop compositions and methods for inhibiting factor D | |
| JP2017524727A5 (enExample) | ||
| JP6461810B2 (ja) | Ｂｐｉｆｂ４タンパク質の変異体 | |
| CN104288781B (zh) | miR‑329在制备预防和/或治疗缺血性眼部疾病的药物中的应用 | |
| CN105079780B (zh) | 一种特异结合trb3的多肽在治疗腹主动脉瘤中的应用 | |
| KR102114880B1 (ko) | 코돈 최적화된 TIF1γ 폴리뉴클레오티드를 포함하는 재조합 벡터 및 이의 용도 | |
| CN104288764B (zh) | Cd146作为预防和/或治疗缺血性眼部疾病的药物靶点的应用 | |
| CN116355901A (zh) | 一种靶向人DMD位点的sgRNA及其应用 | |
| WO2022187671A1 (en) | Compositions and methods for the treatment of hemophilia | |
| WO2003091271A1 (en) | Alternatively spliced nucleic acid molecules | |
| JPWO2009013794A1 (ja) | インスリン分泌誘導剤及び膵臓β細胞増加促進剤 | |
| CN103601808A (zh) | 新型钠肽、制备方法及其在制备基因工程药物中的应用 | |
| AU2001274591B2 (en) | Canine liver cell growth factor | |
| KR20250134237A (ko) | Dr5 도메인 변이체 및 이의 용도 | |
| Seneviratne et al. | 181 M1 MACROPHAGES AND IRF5 EXACERBATE ATHEROSCLEROTIC DISEASE |