JP2016508036A5 - - Google Patents

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Publication number
JP2016508036A5
JP2016508036A5 JP2015550089A JP2015550089A JP2016508036A5 JP 2016508036 A5 JP2016508036 A5 JP 2016508036A5 JP 2015550089 A JP2015550089 A JP 2015550089A JP 2015550089 A JP2015550089 A JP 2015550089A JP 2016508036 A5 JP2016508036 A5 JP 2016508036A5
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JP
Japan
Prior art keywords
seq
fragment
variant
amino acid
acid sequence
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JP2015550089A
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English (en)
Japanese (ja)
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JP6461810B2 (ja
JP2016508036A (ja
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Priority claimed from EP12425208.1A external-priority patent/EP2749569A1/en
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Publication of JP2016508036A5 publication Critical patent/JP2016508036A5/ja
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Publication of JP6461810B2 publication Critical patent/JP6461810B2/ja
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JP2015550089A 2012-12-28 2013-12-27 Bpifb4タンパク質の変異体 Active JP6461810B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12425208.1A EP2749569A1 (en) 2012-12-28 2012-12-28 Variant of BPIFB4 protein
EP12425208.1 2012-12-28
PCT/EP2013/078076 WO2014102343A1 (en) 2012-12-28 2013-12-27 Variant of bpifb4 protein

Publications (3)

Publication Number Publication Date
JP2016508036A JP2016508036A (ja) 2016-03-17
JP2016508036A5 true JP2016508036A5 (enExample) 2017-02-09
JP6461810B2 JP6461810B2 (ja) 2019-01-30

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ID=47715813

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015550089A Active JP6461810B2 (ja) 2012-12-28 2013-12-27 Bpifb4タンパク質の変異体

Country Status (8)

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US (4) US20150344536A1 (enExample)
EP (4) EP2749569A1 (enExample)
JP (1) JP6461810B2 (enExample)
CN (1) CN104955836B (enExample)
AU (1) AU2013369292B2 (enExample)
CA (1) CA2896166A1 (enExample)
ES (2) ES2731126T3 (enExample)
WO (1) WO2014102343A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2749569A1 (en) 2012-12-28 2014-07-02 Annibale Alessandro Puca Variant of BPIFB4 protein
CN104558144B (zh) * 2014-12-30 2017-08-08 深圳市第二人民医院 鼠Bpifb5突变体、蛋白及其应用
CN111094327A (zh) * 2017-08-16 2020-05-01 Lgv1有限公司 Bpifb4蛋白的用于神经元疾病和损伤的vtft同种型
EP4434534A1 (en) 2023-03-22 2024-09-25 ADvantage Therapeutics, Inc. Klotho mrna

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87737A (en) * 1987-09-11 1993-08-18 Genentech Inc Method for culturing polypeptide factor dependent vertebrate recombinant cells
US6391311B1 (en) * 1998-03-17 2002-05-21 Genentech, Inc. Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1
EP1274842A2 (en) * 2000-04-18 2003-01-15 MERCK PATENT GmbH Lipid binding protein 4
WO2002063008A2 (en) 2001-02-08 2002-08-15 Incyte Genomics, Inc. Intracellular signaling molecules
EP1463805B1 (en) 2001-12-17 2014-10-22 The Trustees of The University of Pennsylvania Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses therefor
EP3211085B1 (en) 2003-09-30 2021-03-31 The Trustees of The University of Pennsylvania Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
WO2006022619A2 (en) * 2004-07-22 2006-03-02 Sequenom, Inc. Methods for identifying risk of type ii diabetes and treatments thereof
US9075044B2 (en) * 2006-05-31 2015-07-07 The Children's Hospital Of Philadelphia Compositions and methods for detection and modulation of T cell mediated immune responses against viral vectors utilized for gene therapy
CN101627121A (zh) 2006-12-08 2010-01-13 奥斯瑞根公司 作为治疗干预的靶标的miRNA调控基因和路径
EP2019143A1 (en) 2007-07-23 2009-01-28 Genethon CNS gene delivery using peripheral administration of AAV vectors
WO2010071832A1 (en) 2008-12-19 2010-06-24 Nationwide Children's Hospital Delivery of polynucleotides across the blood brain barrier using recombinant aav9
JP2011231022A (ja) * 2010-04-23 2011-11-17 Ajinomoto Co Inc イミダゾロン誘導体
JP6224459B2 (ja) 2011-02-17 2017-11-01 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 組織特異性を改変し、aav9媒介遺伝子導入を改善するための組成物および方法
WO2013151665A2 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins associated with human disease
EP2749569A1 (en) * 2012-12-28 2014-07-02 Annibale Alessandro Puca Variant of BPIFB4 protein

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