|
US4593089A
(en)
|
1980-07-30 |
1986-06-03 |
Abbott Laboratories |
Fluorescent polarization immunoassay utilizing substituted triazinylaminofluorescein aminoglycosides
|
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
|
US4751190A
(en)
|
1985-07-22 |
1988-06-14 |
Abbott Laboratories |
Fluorescence polarization immunoassay and reagents for use therein
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
JP2529321B2
(ja)
|
1986-04-28 |
1996-08-28 |
エンドトロニックス インコーポレーテッド |
白血球を培養する方法
|
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
ES2052027T5
(es)
|
1988-11-11 |
2005-04-16 |
Medical Research Council |
Clonacion de secuencias de dominio variable de inmunoglobulina.
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US6291158B1
(en)
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
PT1696031E
(pt)
|
1991-12-02 |
2010-06-25 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
|
DE4211351A1
(de)
|
1992-04-04 |
1993-10-07 |
Behringwerke Ag |
Verfahren zur Analyse partikelverstärkter Agglutinationsreaktionen auf Zentrifugalanalysatoren durch Bestimmung der Trübungsaufhellung
|
|
EP0569141A3
(en)
|
1992-04-14 |
1994-10-26 |
Hybritech Inc |
Method for inhibiting the growth of multidrug-resistant tumors by antibodies.
|
|
US5710262A
(en)
|
1992-04-17 |
1998-01-20 |
Dana-Faber Cancer Institute, Inc. |
Nucleic acid encoding HB15 polypeptides
|
|
US5316920A
(en)
|
1992-04-17 |
1994-05-31 |
Dana-Faber Cancer Institute, Inc. |
Lymphocyte activation antigen HB15, a member of the immunoglobulin superfamily
|
|
US20080152586A1
(en)
|
1992-09-25 |
2008-06-26 |
Avipep Pty Limited |
High avidity polyvalent and polyspecific reagents
|
|
EP0672068A4
(en)
|
1992-09-25 |
1997-02-26 |
Commw Scient Ind Res Org |
TARGET MOLECULES BINDING POLYPEPTIDES.
|
|
WO1994009817A1
(en)
|
1992-11-04 |
1994-05-11 |
City Of Hope |
Novel antibody construct
|
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US6113898A
(en)
|
1995-06-07 |
2000-09-05 |
Idec Pharmaceuticals Corporation |
Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
|
|
ATE219517T1
(de)
|
1995-08-18 |
2002-07-15 |
Morphosys Ag |
Protein-/(poly)peptidbibliotheken
|
|
GB9603256D0
(en)
|
1996-02-16 |
1996-04-17 |
Wellcome Found |
Antibodies
|
|
US6541213B1
(en)
|
1996-03-29 |
2003-04-01 |
University Of Washington |
Microscale diffusion immunoassay
|
|
US6699658B1
(en)
|
1996-05-31 |
2004-03-02 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
|
CA2244326C
(en)
|
1997-08-11 |
2006-03-28 |
Shinichi Eda |
Microparticle enhanced light scattering agglutination assay and microparticle reagents therefor
|
|
DE69840412D1
(de)
|
1997-10-31 |
2009-02-12 |
Genentech Inc |
Methoden und zusammensetzungen bestehend aus glykoprotein-glykoformen
|
|
AU3657899A
(en)
|
1998-04-20 |
1999-11-08 |
James E. Bailey |
Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
|
|
US6562622B1
(en)
|
1998-05-08 |
2003-05-13 |
Diatech Pty, Ltd |
Continuous in vitro evolution
|
|
EP1051432B1
(en)
|
1998-12-08 |
2007-01-24 |
Biovation Limited |
Method for reducing immunogenicity of proteins
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
WO2000042430A1
(en)
|
1999-01-15 |
2000-07-20 |
Medtox Scientific, Inc. |
Lateral flow test strip
|
|
HK1042648A1
(zh)
*
|
1999-04-14 |
2002-08-23 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, C/O National Institutes Of Health, Office Of Technology Transfer |
用於诱导对移植物的免疫耐受的含有免疫毒素和抑制树突细胞成熟的试剂的组合物
|
|
US7270969B2
(en)
|
1999-05-05 |
2007-09-18 |
Phylogica Limited |
Methods of constructing and screening diverse expression libraries
|
|
JP4336498B2
(ja)
|
2000-12-12 |
2009-09-30 |
メディミューン，エルエルシー |
延長した半減期を有する分子ならびにその組成物および用途
|
|
MXPA05000511A
(es)
|
2001-07-12 |
2005-09-30 |
Jefferson Foote |
Anticuepros super humanizados.
|
|
US7205159B2
(en)
|
2001-08-20 |
2007-04-17 |
Proteome Systems Intellectual Property Pty Ltd. |
Diagnostic testing process and apparatus
|
|
AR039067A1
(es)
*
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
CA2466845A1
(en)
*
|
2001-11-21 |
2003-06-05 |
Fred Ramsdell |
Manipulation of cytokine levels using cd83 gene products
|
|
US20040185040A1
(en)
|
2001-11-21 |
2004-09-23 |
Celltech R & D Limited |
Modulating immune responses
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
AU2002950779A0
(en)
|
2002-08-15 |
2002-09-12 |
The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland |
A method of immunomodulation
|
|
US7217797B2
(en)
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
WO2004046729A2
(en)
|
2002-11-21 |
2004-06-03 |
The University Of Leicester |
Bodily fluid markers of tissue hypoxia
|
|
EP2258724A1
(en)
|
2002-11-21 |
2010-12-08 |
Celltech R & D, Inc. |
Modulating immune responses using multimerized anti-CD83 antibodies
|
|
US7169898B2
(en)
*
|
2002-12-04 |
2007-01-30 |
Alexander Steinkasserer |
Soluble CD83 proteins and use thereof for the treatment or prevention of a disease or medical condition caused by dysfunction or undesired function of a cellular immune response involving T cells
|
|
EP2368578A1
(en)
|
2003-01-09 |
2011-09-28 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
AU2004245038A1
(en)
|
2003-06-02 |
2004-12-16 |
Alexion Pharmaceuticals, Inc. |
De-immunized anti-CD3 antibody
|
|
EP1673395A1
(en)
|
2003-10-15 |
2006-06-28 |
PDL BioPharma, Inc. |
Alteration of fc-fusion protein serum half-lives by mutagenesis of positions 250, 314 and/or 428 of the heavy chain constant region of ig
|
|
PT1692182E
(pt)
|
2003-11-05 |
2010-05-13 |
Roche Glycart Ag |
Anticorpos de cd20 com uma afinidade de ligação acrescida ao receptor fc e uma função efectora acrescida
|
|
US20070135620A1
(en)
|
2004-11-12 |
2007-06-14 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
JP2008523083A
(ja)
*
|
2004-12-08 |
2008-07-03 |
イムノメディクス， インコーポレイテッド |
炎症性疾患および免疫調節不全疾患、感染性疾患、病的血管新生およびがんの免疫療法および検出のための方法および組成物
|
|
CA2602709A1
(en)
|
2005-03-31 |
2006-10-05 |
Telethon Institute For Child Health Research |
Isolation of inhibitor of ires-mediated translation
|
|
KR20150032915A
(ko)
*
|
2005-04-08 |
2015-03-30 |
아르고스 쎄라퓨틱스 인코포레이티드 |
수지상 세포 조성물 및 방법
|
|
JP2009504685A
(ja)
|
2005-08-15 |
2009-02-05 |
アラーナ・テラピューティクス・リミテッド |
新世界霊長類フレームワーク領域を用いる設計された抗体
|
|
CA2690973A1
(en)
*
|
2006-06-23 |
2007-12-27 |
Paul M. Simon |
Targeted immune conjugates
|
|
EP1985305A1
(en)
|
2007-04-24 |
2008-10-29 |
Vivalis |
Duck embryonic derived stem cell lines for the production of viral vaccines
|
|
EP1995309A1
(en)
|
2007-05-21 |
2008-11-26 |
Vivalis |
Recombinant protein production in avian EBx® cells
|
|
US8197809B2
(en)
|
2008-06-25 |
2012-06-12 |
Korea Research Institute Of Bioscience And Biotechnology |
CD9-specific human antibodies
|
|
AR074369A1
(es)
|
2008-11-20 |
2011-01-12 |
Genentech Inc |
Anticuerpos anti-unc 5b (receptor de netrina) y metodos de uso
|
|
WO2012088290A2
(en)
*
|
2010-12-22 |
2012-06-28 |
Abbott Laboratories |
Tri-variable domain binding proteins and uses thereof
|
|
JP2013040160A
(ja)
*
|
2011-07-01 |
2013-02-28 |
Genentech Inc |
自己免疫疾患を治療するための抗ｃｄ８３アゴニスト抗体の使用
|
|
PT2951208T
(pt)
|
2013-02-01 |
2019-12-30 |
Univ California |
Anticorpos anti-cd83 e sua utilização
|
|
US10870704B2
(en)
|
2014-10-23 |
2020-12-22 |
Kira Biotech Pty Limited |
CD83 binding proteins and uses thereof
|
|
US20200277396A1
(en)
|
2017-09-13 |
2020-09-03 |
Kira Biotech Pty Limited |
Treatment Method
|