CN112955470A - 抗tnfr2抗体及其用途 - Google Patents
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Abstract
一种能够特异性地结合TNFR2的抗体或其抗原结合片段,所述抗体或其抗原结合片段能够调节免疫细胞的功能,可作为药物治疗与免疫异常有关的疾病,例如肿瘤。
Description
PCT国内申请,说明书已公开。
Claims (22)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
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CN201910713742 | 2019-08-02 | ||
CN2019107137421 | 2019-08-02 | ||
PCT/CN2020/106057 WO2021023098A1 (zh) | 2019-08-02 | 2020-07-31 | 抗tnfr2抗体及其用途 |
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CN112955470A true CN112955470A (zh) | 2021-06-11 |
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EP (1) | EP3907240A4 (zh) |
JP (1) | JP7378509B2 (zh) |
KR (1) | KR20220038766A (zh) |
CN (1) | CN112955470A (zh) |
AU (1) | AU2020324183A1 (zh) |
CA (1) | CA3148881A1 (zh) |
WO (1) | WO2021023098A1 (zh) |
Cited By (4)
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WO2023273503A1 (zh) * | 2021-06-30 | 2023-01-05 | 盛禾(中国)生物制药有限公司 | 一种抗tnfr2单域抗体及其制备方法和应用 |
WO2023045606A1 (zh) * | 2021-09-22 | 2023-03-30 | 上海赛金生物医药有限公司 | 抗tnfr2单克隆抗体及其应用 |
WO2023109785A1 (zh) * | 2021-12-14 | 2023-06-22 | 山东先声生物制药有限公司 | 一种用于检测血清中sTNFR2的抗体及试剂盒 |
WO2024037628A1 (zh) * | 2022-08-19 | 2024-02-22 | 盛禾(中国)生物制药有限公司 | 一种双特异性抗体及其应用 |
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CN117836325A (zh) * | 2021-06-22 | 2024-04-05 | 盛禾(中国)生物制药有限公司 | 一种抗tnfr2抗体及其制备方法和应用 |
TW202309096A (zh) * | 2021-07-07 | 2023-03-01 | 香港商高誠生物醫藥(香港)有限公司 | 抗tnfr2抗體及其用途 |
CN116333123A (zh) * | 2021-12-22 | 2023-06-27 | 宝船生物医药科技(上海)有限公司 | 抗tnfr2抗体及其用途 |
TW202333788A (zh) * | 2021-12-28 | 2023-09-01 | 大陸商江蘇先聲藥業有限公司 | 一種抗tnfr2抗體藥物組合物 |
WO2023154799A1 (en) | 2022-02-14 | 2023-08-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Combination immunotherapy for treating cancer |
WO2024030888A2 (en) * | 2022-08-01 | 2024-02-08 | Yale University | Tnfr2 antibodies and methods of using the same |
Citations (1)
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CN109476745A (zh) * | 2016-05-13 | 2019-03-15 | 综合医院公司 | 拮抗性抗肿瘤坏死因子受体超家族抗体 |
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SG10202001779UA (en) | 2015-01-20 | 2020-04-29 | Igm Biosciences Inc | Tumor necrosis factor (tnf) superfamily receptor binding molecules and uses thereof |
AU2016263198C1 (en) * | 2015-05-15 | 2023-10-05 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor superfamily antibodies |
WO2017083525A1 (en) | 2015-11-11 | 2017-05-18 | Opi Vi- Ip Holdco Llc | Composition and methods for anti-tnfr2 antibodies |
WO2017220711A1 (en) * | 2016-06-22 | 2017-12-28 | Universite Paris Est Creteil Val De Marne | Prevention or treatment of hematologic malignancy relapse using a tnfr2 antagonist |
WO2019094559A2 (en) * | 2017-11-09 | 2019-05-16 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor superfamily polypeptides |
JP2022513434A (ja) | 2018-11-15 | 2022-02-08 | ザ ジェネラル ホスピタル コーポレイション | アゴニスト性腫瘍壊死因子受容体スーパーファミリーポリペプチド |
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2020
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CN109476745A (zh) * | 2016-05-13 | 2019-03-15 | 综合医院公司 | 拮抗性抗肿瘤坏死因子受体超家族抗体 |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023273503A1 (zh) * | 2021-06-30 | 2023-01-05 | 盛禾(中国)生物制药有限公司 | 一种抗tnfr2单域抗体及其制备方法和应用 |
WO2023045606A1 (zh) * | 2021-09-22 | 2023-03-30 | 上海赛金生物医药有限公司 | 抗tnfr2单克隆抗体及其应用 |
WO2023109785A1 (zh) * | 2021-12-14 | 2023-06-22 | 山东先声生物制药有限公司 | 一种用于检测血清中sTNFR2的抗体及试剂盒 |
WO2024037628A1 (zh) * | 2022-08-19 | 2024-02-22 | 盛禾(中国)生物制药有限公司 | 一种双特异性抗体及其应用 |
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EP3907240A4 (en) | 2023-02-22 |
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WO2021023098A1 (zh) | 2021-02-11 |
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