JP2016506735A5 - - Google Patents
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- Publication number
- JP2016506735A5 JP2016506735A5 JP2015556259A JP2015556259A JP2016506735A5 JP 2016506735 A5 JP2016506735 A5 JP 2016506735A5 JP 2015556259 A JP2015556259 A JP 2015556259A JP 2015556259 A JP2015556259 A JP 2015556259A JP 2016506735 A5 JP2016506735 A5 JP 2016506735A5
- Authority
- JP
- Japan
- Prior art keywords
- bacillus
- alanine
- glucose
- gfk
- fructose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BJHIKXHVCXFQLS-UYFOZJQFSA-N Fructose Natural products OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CO BJHIKXHVCXFQLS-UYFOZJQFSA-N 0.000 claims 32
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 28
- 229960003767 Alanine Drugs 0.000 claims 26
- QNAYBMKLOCPYGJ-UWTATZPHSA-N L-Alanine Natural products C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 claims 26
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 24
- WQZGKKKJIJFFOK-GASJEMHNSA-N D-Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 17
- 239000008103 glucose Substances 0.000 claims 17
- 239000005715 Fructose Substances 0.000 claims 16
- 210000004666 bacterial spores Anatomy 0.000 claims 16
- 229940037179 Potassium Ion Drugs 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 15
- NPYPAHLBTDXSSS-UHFFFAOYSA-N potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 claims 15
- 229910001414 potassium ion Inorganic materials 0.000 claims 15
- 229960001230 Asparagine Drugs 0.000 claims 12
- DCXYFEDJOCDNAF-UWTATZPHSA-N L-Asparagine Natural products OC(=O)[C@H](N)CC(N)=O DCXYFEDJOCDNAF-UWTATZPHSA-N 0.000 claims 12
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 12
- 229960004295 valine Drugs 0.000 claims 12
- 241000193744 Bacillus amyloliquefaciens Species 0.000 claims 11
- 239000011872 intimate mixture Substances 0.000 claims 9
- 241000193755 Bacillus cereus Species 0.000 claims 8
- UGQMRVRMYYASKQ-KMPDEGCQSA-N Inosine Natural products O[C@H]1[C@H](O)[C@@H](CO)O[C@@H]1N1C(N=CNC2=O)=C2N=C1 UGQMRVRMYYASKQ-KMPDEGCQSA-N 0.000 claims 8
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 claims 8
- 229960003786 inosine Drugs 0.000 claims 8
- 230000035784 germination Effects 0.000 claims 7
- 210000004215 spores Anatomy 0.000 claims 6
- 229940075612 Bacillus cereus Drugs 0.000 claims 5
- 241001328122 Bacillus clausii Species 0.000 claims 5
- 241000194108 Bacillus licheniformis Species 0.000 claims 5
- 241000194103 Bacillus pumilus Species 0.000 claims 5
- 229940075615 Bacillus subtilis Drugs 0.000 claims 5
- 240000008371 Bacillus subtilis Species 0.000 claims 5
- 235000014469 Bacillus subtilis Nutrition 0.000 claims 5
- 241000193171 Clostridium butyricum Species 0.000 claims 4
- 238000001035 drying Methods 0.000 claims 4
- 229940054340 Bacillus coagulans Drugs 0.000 claims 3
- 241000193749 Bacillus coagulans Species 0.000 claims 3
- 241000194106 Bacillus mycoides Species 0.000 claims 3
- 241000193400 Bacillus simplex Species 0.000 claims 3
- 241000305693 Erigeron pumilus Species 0.000 claims 3
- 241000024378 Ilybius subtilis Species 0.000 claims 3
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 3
- 230000036740 Metabolism Effects 0.000 claims 3
- 229960002429 Proline Drugs 0.000 claims 3
- 241000635201 Pumilus Species 0.000 claims 3
- 241000187747 Streptomyces Species 0.000 claims 3
- 238000007605 air drying Methods 0.000 claims 3
- 230000024881 catalytic activity Effects 0.000 claims 3
- 230000000875 corresponding Effects 0.000 claims 3
- 238000002036 drum drying Methods 0.000 claims 3
- 239000000796 flavoring agent Substances 0.000 claims 3
- 235000019634 flavors Nutrition 0.000 claims 3
- 238000004108 freeze drying Methods 0.000 claims 3
- 230000012010 growth Effects 0.000 claims 3
- 230000004060 metabolic process Effects 0.000 claims 3
- 230000035786 metabolism Effects 0.000 claims 3
- 238000001694 spray drying Methods 0.000 claims 3
- 241000193830 Bacillus <bacterium> Species 0.000 claims 2
- 241000194107 Bacillus megaterium Species 0.000 claims 2
- 241000193403 Clostridium Species 0.000 claims 2
- XUJNEKJLAYXESH-REOHCLBHSA-N L-cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- JVTAAEKCZFNVCJ-REOHCLBHSA-M (S)-lactate Chemical compound C[C@H](O)C([O-])=O JVTAAEKCZFNVCJ-REOHCLBHSA-M 0.000 claims 1
- 229960002433 Cysteine Drugs 0.000 claims 1
- 229960002743 Glutamine Drugs 0.000 claims 1
- 239000004201 L-cysteine Substances 0.000 claims 1
- 235000013878 L-cysteine Nutrition 0.000 claims 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims 1
- 229940116871 L-lactate Drugs 0.000 claims 1
- 239000004395 L-leucine Substances 0.000 claims 1
- 235000019454 L-leucine Nutrition 0.000 claims 1
- 229960005190 Phenylalanine Drugs 0.000 claims 1
- 239000004473 Threonine Substances 0.000 claims 1
- 239000002702 enteric coating Substances 0.000 claims 1
- 238000009505 enteric coating Methods 0.000 claims 1
- 229960003136 leucine Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229960002898 threonine Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361849973P | 2013-02-06 | 2013-02-06 | |
| US61/849,973 | 2013-02-06 | ||
| US14/174,099 US9447376B2 (en) | 2013-02-06 | 2014-02-06 | Dried spore germinative compound mixtures |
| PCT/US2014/015076 WO2014124120A1 (en) | 2013-02-06 | 2014-02-06 | Dried spore germinative compound mixtures |
| US14/174,099 | 2014-02-06 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019063618A Division JP2019115357A (ja) | 2013-02-06 | 2019-03-28 | 乾燥した芽胞発芽性化合物の混合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016506735A JP2016506735A (ja) | 2016-03-07 |
| JP2016506735A5 true JP2016506735A5 (zh) | 2017-03-16 |
| JP6552416B2 JP6552416B2 (ja) | 2019-07-31 |
Family
ID=51259538
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015556259A Active JP6552416B2 (ja) | 2013-02-06 | 2014-02-06 | 乾燥した芽胞発芽性化合物の混合物 |
| JP2019063618A Withdrawn JP2019115357A (ja) | 2013-02-06 | 2019-03-28 | 乾燥した芽胞発芽性化合物の混合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019063618A Withdrawn JP2019115357A (ja) | 2013-02-06 | 2019-03-28 | 乾燥した芽胞発芽性化合物の混合物 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US9447376B2 (zh) |
| EP (1) | EP2954041B1 (zh) |
| JP (2) | JP6552416B2 (zh) |
| KR (1) | KR102302522B1 (zh) |
| CN (1) | CN105121622A (zh) |
| AU (1) | AU2014214917B2 (zh) |
| BR (1) | BR112015018783B1 (zh) |
| CA (1) | CA2899606C (zh) |
| DK (1) | DK2954041T3 (zh) |
| EA (1) | EA034962B1 (zh) |
| ES (1) | ES2699438T3 (zh) |
| HR (1) | HRP20181498T1 (zh) |
| HU (1) | HUE040216T2 (zh) |
| LT (1) | LT2954041T (zh) |
| MX (1) | MX358960B (zh) |
| PL (1) | PL2954041T3 (zh) |
| PT (1) | PT2954041T (zh) |
| RS (1) | RS58158B1 (zh) |
| SI (1) | SI2954041T1 (zh) |
| WO (1) | WO2014124120A1 (zh) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2015016399A (es) * | 2013-05-31 | 2016-03-16 | Novozymes Bioag As | Composiciones y metodos para mejorar la germinacion. |
| MX2016005303A (es) | 2013-10-25 | 2016-08-11 | Nch Corp | Sistema de suministro y composicion probiotica para animales y plantas. |
| PE20170238A1 (es) | 2014-05-23 | 2017-04-05 | Nch Corp | Metodo para la mejora de la calidad del agua de estanques para acuicultura |
| US10766799B2 (en) | 2014-05-23 | 2020-09-08 | Nch Corporation | Method for improving quality of aquaculture pond water using a nutrient germinant composition and spore incubation method |
| WO2016196680A1 (en) * | 2015-06-01 | 2016-12-08 | Robert Caron | Biofilm control and frack fluid production using bacillus subtilis activated with gfak |
| CN105602864B (zh) * | 2015-12-19 | 2019-02-12 | 广州百农基生物技术有限公司 | 用于畜禽养殖场现场发酵的纳豆芽孢杆菌制剂及应用 |
| CN105439725A (zh) * | 2015-12-19 | 2016-03-30 | 佛山市艳晖生物科技有限公司 | 一种用于农场现场发酵的多粘类芽孢杆菌药肥及其应用 |
| CN105594698B (zh) * | 2015-12-19 | 2018-06-01 | 佛山市艳晖生物科技有限公司 | 一种侧孢芽孢杆菌可湿性粉剂的制备方法 |
| CN105439724A (zh) * | 2015-12-19 | 2016-03-30 | 佛山市艳晖生物科技有限公司 | 一种用于农场现场发酵的胶冻样芽孢杆菌菌肥及其应用 |
| CN105439726A (zh) * | 2015-12-19 | 2016-03-30 | 佛山市艳晖生物科技有限公司 | 一种应用于农场现场发酵的巨大芽孢杆菌菌肥及其应用 |
| CN105439723A (zh) * | 2015-12-19 | 2016-03-30 | 佛山市艳晖生物科技有限公司 | 一种用于农场现场发酵的解淀粉芽孢杆菌药肥及其应用 |
| WO2017176872A1 (en) | 2016-04-05 | 2017-10-12 | Nch Corporation | Nutrient rich germinant composition and spore incubation method |
| US10897922B2 (en) | 2016-04-05 | 2021-01-26 | Nch Corporation | Composition and method for germinative compounds in probiotic food and beverage products for human consumption |
| US12097226B2 (en) | 2016-04-05 | 2024-09-24 | Nch Corporation | System and method for using a single-serve nutrient spore composition for small scale farm applications |
| WO2018026446A1 (en) * | 2016-07-30 | 2018-02-08 | Novozymes Bioag A/S | Composition comprising non-germinant and bacterial spores |
| CN111295197A (zh) * | 2017-11-03 | 2020-06-16 | Nch公司 | 供人食用的益生菌食品和饮品中萌发化合物的组合物和方法 |
| WO2019168627A1 (en) * | 2018-02-28 | 2019-09-06 | Nch Corporation | Method for improving quality of aquaculture pond water using a nutrient germinant composition and spore incubation method |
| EP3784807A1 (en) * | 2018-04-23 | 2021-03-03 | Evonik Operations GmbH | Synbiotic compositions |
| US11401500B2 (en) | 2018-08-29 | 2022-08-02 | Nch Corporation | System, method, and composition for incubating spores for use in aquaculture, agriculture, wastewater, and environmental remediation applications |
| CN109619182B (zh) * | 2018-11-08 | 2022-07-08 | 中国农业科学院农产品加工研究所 | 芽孢萌发剂及应用 |
| WO2020264009A1 (en) * | 2019-06-24 | 2020-12-30 | Noxilizer Inc. | Method of manufacturing biological indicators |
| US11884960B2 (en) * | 2019-08-16 | 2024-01-30 | Terragene Llc | Biological indicator for determining the efficacy of a steam or heat sterilization process and its method of use |
| CN110904002B (zh) * | 2019-11-25 | 2022-04-29 | 天津大学 | 一种生物移除四环素类抗生素的方法 |
| WO2021159068A1 (en) | 2020-02-06 | 2021-08-12 | Nch Corportion | Composition and method of using germinative compounds in probiotics for inflammation reduction in humans |
| WO2021194930A1 (en) * | 2020-03-23 | 2021-09-30 | Nch Corporation | System and method for using a single-serve nutrient spore composition for small scale farm applications |
| KR20230156811A (ko) * | 2020-03-24 | 2023-11-14 | 트리플더블유 리미티드 | 바실러스 코아굴란스 포자 조성물을 사용한 유기 폐기물로부터의 락트산의 생산 |
| WO2022226608A1 (pt) * | 2021-04-30 | 2022-11-03 | Total Biotecnologia Indústria E Comércio S/A | Ativação das funções bionematicida e promotora do crescimento vegetal em uma solução biotecnológica |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995025163A1 (en) * | 1994-03-15 | 1995-09-21 | Philom Bios Inc. | Methods for the production of fungal spores and compositions thereof |
| WO1999005310A1 (en) * | 1997-07-28 | 1999-02-04 | Minnesota Mining And Manufacturing Company | Spore germination media |
| US6187555B1 (en) * | 1998-04-16 | 2001-02-13 | 3M Innovative Properties Company | Spores with increased sensitivity to sterilants using additives that bind to sterilant-sensitive sites |
| US6849256B1 (en) | 1999-11-08 | 2005-02-01 | Ganeden Biotech Incorporated | Inhibition of pathogens by probiotic bacteria |
| WO2001066471A2 (en) * | 2000-03-08 | 2001-09-13 | Hercules Incorporated | Control of spore forming bacteria in aqueous systems |
| WO2003039260A2 (en) * | 2001-11-05 | 2003-05-15 | Ganeden Biotech Inc | PROBIOTIC COMPOSITIONS |
| US7358072B2 (en) | 2004-10-15 | 2008-04-15 | Zuchem, Inc | Fermentative production of mannitol |
| AU2009234015A1 (en) | 2008-04-07 | 2009-10-15 | Bayer Intellectual Property Gmbh | Stable aqueous spore-containing formulation |
| DK2379704T3 (da) * | 2008-12-19 | 2013-03-25 | Chr Hansen As | Et galderesistent bacillus-præparat der udskiller essentielle aminosyrer på et højt niveau |
| EP2379705B2 (en) | 2008-12-19 | 2019-10-02 | Chr. Hansen A/S | A bile resistant bacillus composition |
| KR20130102541A (ko) * | 2010-08-25 | 2013-09-17 | 테이트 앤드 라일 인그리디언츠 어메리카즈 엘엘씨 | 신바이오틱 제품 |
| CN103281905B (zh) | 2010-12-21 | 2016-10-19 | 拜尔作物科学有限合伙公司 | 芽孢杆菌属的砂纸突变体及其用于增进植物生长、促进植物健康及控制疾病和害虫的方法 |
| CN102515927B (zh) * | 2011-09-21 | 2013-09-11 | 周法永 | 一种药效型微生物肥料及其制备方法和应用 |
| US20140295482A1 (en) * | 2011-11-02 | 2014-10-02 | Texas Tech University System | Media Compositions for Promoting Bacterial and Fungal Growth |
-
2014
- 2014-02-06 KR KR1020157021934A patent/KR102302522B1/ko active IP Right Grant
- 2014-02-06 PL PL14749483T patent/PL2954041T3/pl unknown
- 2014-02-06 CA CA2899606A patent/CA2899606C/en active Active
- 2014-02-06 JP JP2015556259A patent/JP6552416B2/ja active Active
- 2014-02-06 MX MX2015010124A patent/MX358960B/es active IP Right Grant
- 2014-02-06 CN CN201480007598.5A patent/CN105121622A/zh active Pending
- 2014-02-06 WO PCT/US2014/015076 patent/WO2014124120A1/en active Application Filing
- 2014-02-06 PT PT14749483T patent/PT2954041T/pt unknown
- 2014-02-06 US US14/174,099 patent/US9447376B2/en active Active
- 2014-02-06 EP EP14749483.5A patent/EP2954041B1/en active Active
- 2014-02-06 AU AU2014214917A patent/AU2014214917B2/en active Active
- 2014-02-06 BR BR112015018783-8A patent/BR112015018783B1/pt active IP Right Grant
- 2014-02-06 SI SI201430879T patent/SI2954041T1/sl unknown
- 2014-02-06 RS RS20181083A patent/RS58158B1/sr unknown
- 2014-02-06 EA EA201591463A patent/EA034962B1/ru unknown
- 2014-02-06 DK DK14749483.5T patent/DK2954041T3/en active
- 2014-02-06 ES ES14749483T patent/ES2699438T3/es active Active
- 2014-02-06 HU HUE14749483A patent/HUE040216T2/hu unknown
- 2014-02-06 LT LTEP14749483.5T patent/LT2954041T/lt unknown
-
2016
- 2016-08-26 US US15/248,328 patent/US10308909B2/en active Active
-
2018
- 2018-09-20 HR HRP20181498TT patent/HRP20181498T1/hr unknown
-
2019
- 2019-03-28 JP JP2019063618A patent/JP2019115357A/ja not_active Withdrawn
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