JP2016504046A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016504046A5 JP2016504046A5 JP2015552899A JP2015552899A JP2016504046A5 JP 2016504046 A5 JP2016504046 A5 JP 2016504046A5 JP 2015552899 A JP2015552899 A JP 2015552899A JP 2015552899 A JP2015552899 A JP 2015552899A JP 2016504046 A5 JP2016504046 A5 JP 2016504046A5
- Authority
- JP
- Japan
- Prior art keywords
- modified
- egfr
- oligonucleotide
- sequence
- modified sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361752117P | 2013-01-14 | 2013-01-14 | |
| US61/752,117 | 2013-01-14 | ||
| PCT/US2014/011496 WO2014110577A1 (en) | 2013-01-14 | 2014-01-14 | Dnazyme for silencing the expression of egfr |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016504046A JP2016504046A (ja) | 2016-02-12 |
| JP2016504046A5 true JP2016504046A5 (enExample) | 2017-02-09 |
| JP6574136B2 JP6574136B2 (ja) | 2019-09-18 |
Family
ID=51167450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015552899A Expired - Fee Related JP6574136B2 (ja) | 2013-01-14 | 2014-01-14 | Egfrの発現をサイレンシングするためのdnaザイム |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9856480B2 (enExample) |
| EP (1) | EP2943578B1 (enExample) |
| JP (1) | JP6574136B2 (enExample) |
| KR (1) | KR20150136588A (enExample) |
| CN (1) | CN105264084A (enExample) |
| CA (1) | CA2898200A1 (enExample) |
| WO (1) | WO2014110577A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220061311A1 (en) * | 2018-11-05 | 2022-03-03 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for reducing cryopreservation toxicity |
| IL302594A (en) * | 2020-11-09 | 2023-07-01 | 1E Therapeutics Ltd | Catalytic sequence based methods of treating or preventing bacterial infections |
| CN116286831B (zh) * | 2023-01-29 | 2024-02-20 | 珠海市人民医院 | 靶向egfr t790m突变体的核酸适配体及其在制备治疗肺癌药物中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040031072A1 (en) * | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
| US7365185B2 (en) * | 2000-07-19 | 2008-04-29 | Monsanto Technology Llc | Genomic plant sequences and uses thereof |
| AU3497701A (en) * | 2000-02-08 | 2001-08-20 | Ribozyme Pharmaceuticals, Inc. | Nucleozymes with endonuclease activity |
| EP1767632A3 (en) * | 2001-05-29 | 2009-12-30 | Sirna Therpeutics, Inc. | A method for local administration of synthetic double-stranded oligonucleotides targeting a VEGF receptor |
| US6890719B2 (en) * | 2002-05-10 | 2005-05-10 | The Board Of Trustess Of The University Of Illinois | Fluorescence based biosensor |
| GB0224663D0 (en) * | 2002-10-23 | 2002-12-04 | Isis Innovation | DNAzyme |
| WO2005108570A1 (ja) * | 2004-05-11 | 2005-11-17 | National University Corporation Yokohama National University | 核酸酵素複合体 |
| EP1766068A4 (en) * | 2004-06-04 | 2010-03-03 | Genentech Inc | EGFR Mutations |
| BRPI0607235A2 (pt) * | 2005-02-24 | 2009-08-25 | Amgen Inc | mutações do receptor do fator de crescimento epidérmico |
| CA2683559C (en) | 2007-04-13 | 2019-09-24 | Dana Farber Cancer Institute, Inc. | Methods for treating cancer resistant to erbb therapeutics |
| CN103080314B (zh) * | 2010-09-30 | 2016-04-13 | Lsip基金运营联合公司 | 显性突变基因表达抑制剂 |
-
2014
- 2014-01-14 CA CA2898200A patent/CA2898200A1/en not_active Abandoned
- 2014-01-14 CN CN201480004837.1A patent/CN105264084A/zh active Pending
- 2014-01-14 EP EP14737655.2A patent/EP2943578B1/en active Active
- 2014-01-14 KR KR1020157022001A patent/KR20150136588A/ko not_active Ceased
- 2014-01-14 JP JP2015552899A patent/JP6574136B2/ja not_active Expired - Fee Related
- 2014-01-14 WO PCT/US2014/011496 patent/WO2014110577A1/en not_active Ceased
- 2014-01-14 US US14/760,904 patent/US9856480B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102129636B1 (ko) | Pd-l1 축 결합 길항제 및 vegf 길항제를 사용하여 암을 치료하는 방법 | |
| JP5719322B2 (ja) | 腫瘍の治療 | |
| Atreya et al. | Systemic therapy for metastatic colorectal cancer: from current standards to future molecular targeted approaches | |
| JP2017101072A (ja) | ホスファチジルイノシトール−3−キナーゼ経路バイオマーカー | |
| TW201022214A (en) | Treatment method | |
| US11820813B2 (en) | Anti-neurotensin long fragment antibodies and uses thereof | |
| DE602007007985D1 (de) | Als inhibitoren von proteinkinasen geeignete aminopyrimidine | |
| TW201032796A (en) | Treatment of lung cancer with a PARP inhibitor in combination with a growth factor inhibitor | |
| CN106687135A (zh) | 使用pd‑1轴结合拮抗剂和il‑17结合拮抗剂治疗癌症的方法 | |
| CN107427501B (zh) | 通过联合使用治疗癌症的方法 | |
| von Achenbach et al. | Epidermal growth factor receptor and ligand family expression and activity in glioblastoma | |
| TW202129013A (zh) | 偵測編碼新生抗原之融合基因之方法 | |
| JP2024041781A (ja) | チロシンキナーゼ阻害剤と併用してegf/egfr経路を抑制する方法および組成物 | |
| US20190151346A1 (en) | Combinations therapies for the treatment of cancer | |
| Kjær et al. | Cetuximab resistance in squamous carcinomas of the upper aerodigestive tract is driven by receptor tyrosine kinase plasticity: potential for mAb mixtures | |
| JP2016504046A5 (enExample) | ||
| US10077303B2 (en) | Anti-neurotensin antibodies and uses thereof | |
| JP2022527499A (ja) | Her2エクソン21挿入を有するがん細胞に対する抗腫瘍活性を有する化合物 | |
| JP2014525270A5 (enExample) | ||
| Zhang et al. | Recent trend for egfr-based and alk-based targets: A patent analysis | |
| JP2023507751A (ja) | 膵臓がんの治療および予後 | |
| US20230321087A1 (en) | Fgfr inhibitor combination therapies | |
| US12351878B2 (en) | Identification of HER2 mutations in lung cancer and methods of treatment | |
| HK40097045A (zh) | 治疗组合物用於治疗上皮源性肿瘤患者的用途 | |
| Observation et al. | 6 Neoplastic Disease |