JP2016503159A5 - - Google Patents
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- Publication number
- JP2016503159A5 JP2016503159A5 JP2015547053A JP2015547053A JP2016503159A5 JP 2016503159 A5 JP2016503159 A5 JP 2016503159A5 JP 2015547053 A JP2015547053 A JP 2015547053A JP 2015547053 A JP2015547053 A JP 2015547053A JP 2016503159 A5 JP2016503159 A5 JP 2016503159A5
- Authority
- JP
- Japan
- Prior art keywords
- target substance
- 2bound
- magnetic nanoparticles
- bound
- biological sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000013076 target substance Substances 0.000 claims 32
- 239000002122 magnetic nanoparticle Substances 0.000 claims 25
- 239000012472 biological sample Substances 0.000 claims 14
- 238000000034 method Methods 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 9
- 239000000523 sample Substances 0.000 claims 7
- 239000011230 binding agent Substances 0.000 claims 5
- 238000000338 in vitro Methods 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000013016 damping Methods 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 239000013074 reference sample Substances 0.000 claims 1
- 238000000264 spin echo pulse sequence Methods 0.000 claims 1
- 239000013077 target material Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3886/DEL/2012 | 2012-12-17 | ||
| IN3886DE2012 | 2012-12-17 | ||
| GB1301992.2 | 2013-02-05 | ||
| GB201301992A GB201301992D0 (en) | 2013-02-05 | 2013-02-05 | In-vitro magnetic resonance detection of a target substance |
| PCT/EP2013/076569 WO2014095645A1 (en) | 2012-12-17 | 2013-12-13 | In-vitro magnetic resonance detection of a target substance |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016503159A JP2016503159A (ja) | 2016-02-01 |
| JP2016503159A5 true JP2016503159A5 (https=) | 2017-01-26 |
| JP6371303B2 JP6371303B2 (ja) | 2018-08-08 |
Family
ID=49759340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015547053A Expired - Fee Related JP6371303B2 (ja) | 2012-12-17 | 2013-12-13 | 目標物質のインビトロ磁気共鳴検出 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10156567B2 (https=) |
| EP (1) | EP2932289A1 (https=) |
| JP (1) | JP6371303B2 (https=) |
| CN (1) | CN104871026B (https=) |
| WO (1) | WO2014095645A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6244289B2 (ja) * | 2014-10-29 | 2017-12-06 | 学校法人 神野学園 | クドア・セプテンプンクタータの検出方法 |
| EP4607201A3 (en) | 2016-07-21 | 2025-10-22 | Siemens Healthcare Diagnostics, Inc. | Magnetic shielding for ivd automation system |
| CN107478834A (zh) * | 2017-09-05 | 2017-12-15 | 杨蕾 | 一种检测沙门氏菌磁共振成像试剂盒的制备方法 |
| EP3575813B1 (en) * | 2018-05-30 | 2022-06-29 | Siemens Healthcare GmbH | Quantitative mapping of a magnetic resonance imaging parameter by data-driven signal-model learning |
| CN109658468B (zh) * | 2018-12-12 | 2022-12-13 | 深圳先进技术研究院 | 磁共振参数成像方法、装置、设备及存储介质 |
| EP4047356A4 (en) * | 2019-10-17 | 2023-11-22 | Riken | DETECTION METHOD AND SYSTEM FOR DETECTION OF MASTITIS IN A DOMESTIC ANIMAL |
| IL295143B2 (en) * | 2020-02-13 | 2026-02-01 | Hoffmann La Roche | A method for determining the loading state of AAV particles using nuclear magnetic resonance relaxometry |
| CN112611868A (zh) * | 2020-12-18 | 2021-04-06 | 厦门大学 | 一种用于磁共振分析方法检测新型冠状病毒的探针及其制备方法 |
| EP4423520A4 (en) * | 2021-10-28 | 2025-09-03 | Massachusetts Inst Technology | MAGNETIC RESONANCE MICRORELAXOMETRY (MMRR) FOR RAPID AND NON-INVASIVE DETECTION OF SENESCENCE IN MESENCHYMAL STEM CELLS |
| AU2024314139A1 (en) * | 2023-06-20 | 2026-01-08 | Kuva Labs Inc. | Methods for magnetic resonance molecular imaging of nanoconstructs and uses thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030028093A1 (en) * | 2001-04-20 | 2003-02-06 | Yong Ke | Exponential decay modeling in spectroscopy |
| US7088102B1 (en) | 2005-03-03 | 2006-08-08 | Varian, Inc. | Rapid sample multiplexing |
| US7781228B2 (en) | 2005-04-07 | 2010-08-24 | Menon & Associates, Inc. | Magnetic resonance system and method to detect and confirm analytes |
| CA2606924C (en) | 2005-05-09 | 2013-04-16 | The General Hospital Corporation | Water relaxation-based sensors |
| US7560289B2 (en) * | 2005-11-16 | 2009-07-14 | Chin-Yih Rex Hong | Methods of quantitatively measuring biomolecules |
| US20070166730A1 (en) | 2006-01-19 | 2007-07-19 | Menon & Associates, Inc. | Magnetic resonance system and method to detect and confirm analytes |
| DE102007009494A1 (de) * | 2007-02-27 | 2008-08-28 | Bayer Healthcare Ag | Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung |
| US8421458B2 (en) * | 2007-09-28 | 2013-04-16 | T2 Biosystems, Inc. | NMR diagnostics by means of a plastic sample container |
| WO2009045551A1 (en) | 2007-10-04 | 2009-04-09 | The General Hospital Corporation | Miniaturized magnetic resonance systems and methods |
| DE102007049701B4 (de) | 2007-10-17 | 2010-09-23 | Bruker Biospin Ag | NMR-Messkopf mit mehreren Resonatorsystemen zur simultanen Vermessung mehrerer Messproben in einem gekoppelten Mode |
| CA2704674A1 (en) * | 2007-11-06 | 2009-05-14 | T2 Biosystems, Inc. | Small magnet and rf coil for magnetic resonance relaxometry |
| AU2008343871B2 (en) * | 2007-12-21 | 2014-02-06 | T2 Biosystems, Inc. | Magnetic resonance system with implantable components and methods of use thereof |
| CN102439474A (zh) * | 2009-03-25 | 2012-05-02 | 皇家飞利浦电子股份有限公司 | 利用r2和r2*映射的细胞内和细胞外spio试剂的量化 |
| DE102010013900B4 (de) * | 2010-04-01 | 2013-01-03 | Hochschule Für Angewandte Wissenschaften Fachhochschule Würzburg-Schweinfurt | Verfahren zur Bildgebung mittels magnetischer Kleinstpartikel sowie Vorrichtung hierfür |
| US20110262989A1 (en) | 2010-04-21 | 2011-10-27 | Nanomr, Inc. | Isolating a target analyte from a body fluid |
| WO2012044387A2 (en) | 2010-07-06 | 2012-04-05 | T2 Biosystems, Inc. | Methods and compositions for detection of analytes |
| US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| US8409807B2 (en) * | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| CA2815085C (en) * | 2010-10-22 | 2022-06-21 | T2 Biosystems, Inc. | Nmr systems and methods for the rapid detection of analytes |
| WO2012129281A2 (en) * | 2011-03-22 | 2012-09-27 | The General Hospital Corporation | Detection of targets using magnetic resonance |
| WO2013010080A1 (en) * | 2011-07-13 | 2013-01-17 | T2 Biosystems, Inc. | Nmr methods for monitoring blood clot formation |
| JP5879189B2 (ja) | 2012-04-26 | 2016-03-08 | 株式会社日立製作所 | 交流磁場を用いた磁気的免疫検査方法及び検査装置 |
| JP2014095691A (ja) | 2012-09-13 | 2014-05-22 | Aspect Imaging Ltd | 常磁性物質を使用する体外診断用途のための手段及び方法 |
| CN104614513B (zh) * | 2015-01-26 | 2016-05-25 | 国家纳米科学中心 | 一种基于磁分离的弛豫时间免疫传感分析方法 |
| CN105920620A (zh) * | 2016-06-21 | 2016-09-07 | 东南大学 | 磁性荧光多模态纳米生物探针及其制备方法和应用 |
-
2013
- 2013-12-13 US US14/652,852 patent/US10156567B2/en not_active Expired - Fee Related
- 2013-12-13 EP EP13803073.9A patent/EP2932289A1/en not_active Withdrawn
- 2013-12-13 WO PCT/EP2013/076569 patent/WO2014095645A1/en not_active Ceased
- 2013-12-13 CN CN201380065739.4A patent/CN104871026B/zh not_active Expired - Fee Related
- 2013-12-13 JP JP2015547053A patent/JP6371303B2/ja not_active Expired - Fee Related
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