JP2016503159A5 - - Google Patents
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- Publication number
- JP2016503159A5 JP2016503159A5 JP2015547053A JP2015547053A JP2016503159A5 JP 2016503159 A5 JP2016503159 A5 JP 2016503159A5 JP 2015547053 A JP2015547053 A JP 2015547053A JP 2015547053 A JP2015547053 A JP 2015547053A JP 2016503159 A5 JP2016503159 A5 JP 2016503159A5
- Authority
- JP
- Japan
- Prior art keywords
- target substance
- 2bound
- magnetic nanoparticles
- bound
- biological sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013076 target substance Substances 0.000 claims 32
- 239000002122 magnetic nanoparticle Substances 0.000 claims 25
- 239000012472 biological sample Substances 0.000 claims 14
- 238000000034 method Methods 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 9
- 239000000523 sample Substances 0.000 claims 7
- 239000011230 binding agent Substances 0.000 claims 5
- 238000000338 in vitro Methods 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000013016 damping Methods 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 239000013074 reference sample Substances 0.000 claims 1
- 238000000264 spin echo pulse sequence Methods 0.000 claims 1
- 239000013077 target material Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3886/DEL/2012 | 2012-12-17 | ||
| IN3886DE2012 | 2012-12-17 | ||
| GB1301992.2 | 2013-02-05 | ||
| GB201301992A GB201301992D0 (en) | 2013-02-05 | 2013-02-05 | In-vitro magnetic resonance detection of a target substance |
| PCT/EP2013/076569 WO2014095645A1 (en) | 2012-12-17 | 2013-12-13 | In-vitro magnetic resonance detection of a target substance |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016503159A JP2016503159A (ja) | 2016-02-01 |
| JP2016503159A5 true JP2016503159A5 (https=) | 2017-01-26 |
| JP6371303B2 JP6371303B2 (ja) | 2018-08-08 |
Family
ID=49759340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015547053A Expired - Fee Related JP6371303B2 (ja) | 2012-12-17 | 2013-12-13 | 目標物質のインビトロ磁気共鳴検出 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10156567B2 (https=) |
| EP (1) | EP2932289A1 (https=) |
| JP (1) | JP6371303B2 (https=) |
| CN (1) | CN104871026B (https=) |
| WO (1) | WO2014095645A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6244289B2 (ja) * | 2014-10-29 | 2017-12-06 | 学校法人 神野学園 | クドア・セプテンプンクタータの検出方法 |
| US11385224B2 (en) | 2016-07-21 | 2022-07-12 | Siemens Healthcare Diagnostics Inc. | Magnetic shielding for IVD automation system |
| CN107478834A (zh) * | 2017-09-05 | 2017-12-15 | 杨蕾 | 一种检测沙门氏菌磁共振成像试剂盒的制备方法 |
| EP3575813B1 (en) * | 2018-05-30 | 2022-06-29 | Siemens Healthcare GmbH | Quantitative mapping of a magnetic resonance imaging parameter by data-driven signal-model learning |
| CN109658468B (zh) * | 2018-12-12 | 2022-12-13 | 深圳先进技术研究院 | 磁共振参数成像方法、装置、设备及存储介质 |
| EP4047356A4 (en) * | 2019-10-17 | 2023-11-22 | Riken | DETECTION METHOD AND SYSTEM FOR DETECTION OF MASTITIS IN A DOMESTIC ANIMAL |
| IL295143B2 (en) * | 2020-02-13 | 2026-02-01 | Hoffmann La Roche | A method for determining the loading state of AAV particles using nuclear magnetic resonance relaxometry |
| CN112611868A (zh) * | 2020-12-18 | 2021-04-06 | 厦门大学 | 一种用于磁共振分析方法检测新型冠状病毒的探针及其制备方法 |
| JP7825308B2 (ja) * | 2021-10-28 | 2026-03-06 | マサチューセッツ インスティテュート オブ テクノロジー | 間葉系幹細胞の老化を迅速かつ非侵襲的に検出するためのマイクロ磁気共鳴リラクソメトリー(μMRR) |
| US20250000384A1 (en) * | 2023-06-20 | 2025-01-02 | Regents Of The University Of Michigan | Methods for magnetic resonance imaging of nanoconstructs and uses thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030028093A1 (en) * | 2001-04-20 | 2003-02-06 | Yong Ke | Exponential decay modeling in spectroscopy |
| US7088102B1 (en) | 2005-03-03 | 2006-08-08 | Varian, Inc. | Rapid sample multiplexing |
| US7781228B2 (en) * | 2005-04-07 | 2010-08-24 | Menon & Associates, Inc. | Magnetic resonance system and method to detect and confirm analytes |
| CA2606924C (en) | 2005-05-09 | 2013-04-16 | The General Hospital Corporation | Water relaxation-based sensors |
| US7560289B2 (en) * | 2005-11-16 | 2009-07-14 | Chin-Yih Rex Hong | Methods of quantitatively measuring biomolecules |
| US20070166730A1 (en) | 2006-01-19 | 2007-07-19 | Menon & Associates, Inc. | Magnetic resonance system and method to detect and confirm analytes |
| DE102007009494A1 (de) * | 2007-02-27 | 2008-08-28 | Bayer Healthcare Ag | Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung |
| WO2009045354A1 (en) | 2007-09-28 | 2009-04-09 | T2 Biosystems, Inc. | Nmr diagnostics by means of a plastic sample container |
| US20110091987A1 (en) | 2007-10-04 | 2011-04-21 | Ralph Weissleder | Miniaturized Magnetic Resonance Systems and Methods |
| DE102007049701B4 (de) | 2007-10-17 | 2010-09-23 | Bruker Biospin Ag | NMR-Messkopf mit mehreren Resonatorsystemen zur simultanen Vermessung mehrerer Messproben in einem gekoppelten Mode |
| AU2008325088A1 (en) * | 2007-11-06 | 2009-05-14 | T2 Biosystems, Inc. | Small magnet and RF coil for magnetic resonance relaxometry |
| AU2008343871B2 (en) * | 2007-12-21 | 2014-02-06 | T2 Biosystems, Inc. | Magnetic resonance system with implantable components and methods of use thereof |
| BRPI1006278A2 (pt) * | 2009-03-25 | 2017-05-30 | Koninklijke Emballage Ind Van Leer B V | metodo para avaliação quantitativa de celulas marcadas por agente magnetico em um paciente meio de armazenamento digital e sistema para avaliação quantitativa de celulas marcadas por agente magnetico em um paciente |
| DE102010013900B4 (de) * | 2010-04-01 | 2013-01-03 | Hochschule Für Angewandte Wissenschaften Fachhochschule Würzburg-Schweinfurt | Verfahren zur Bildgebung mittels magnetischer Kleinstpartikel sowie Vorrichtung hierfür |
| US20110262989A1 (en) | 2010-04-21 | 2011-10-27 | Nanomr, Inc. | Isolating a target analyte from a body fluid |
| WO2012044387A2 (en) | 2010-07-06 | 2012-04-05 | T2 Biosystems, Inc. | Methods and compositions for detection of analytes |
| WO2012054639A2 (en) * | 2010-10-22 | 2012-04-26 | T2 Biosystems, Inc. | Nmr systems and methods for the rapid detection of analytes |
| US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| US8409807B2 (en) * | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| WO2012129325A1 (en) * | 2011-03-22 | 2012-09-27 | The General Hospital Corporation | Molecular analysis of tumor samples |
| EP3321373B1 (en) * | 2011-07-13 | 2020-01-15 | T2 Biosystems, Inc. | Nmr methods for monitoring blood clot formation |
| JP5879189B2 (ja) * | 2012-04-26 | 2016-03-08 | 株式会社日立製作所 | 交流磁場を用いた磁気的免疫検査方法及び検査装置 |
| JP2014095691A (ja) * | 2012-09-13 | 2014-05-22 | Aspect Imaging Ltd | 常磁性物質を使用する体外診断用途のための手段及び方法 |
| CN104614513B (zh) * | 2015-01-26 | 2016-05-25 | 国家纳米科学中心 | 一种基于磁分离的弛豫时间免疫传感分析方法 |
| CN105920620A (zh) | 2016-06-21 | 2016-09-07 | 东南大学 | 磁性荧光多模态纳米生物探针及其制备方法和应用 |
-
2013
- 2013-12-13 EP EP13803073.9A patent/EP2932289A1/en not_active Withdrawn
- 2013-12-13 CN CN201380065739.4A patent/CN104871026B/zh not_active Expired - Fee Related
- 2013-12-13 JP JP2015547053A patent/JP6371303B2/ja not_active Expired - Fee Related
- 2013-12-13 WO PCT/EP2013/076569 patent/WO2014095645A1/en not_active Ceased
- 2013-12-13 US US14/652,852 patent/US10156567B2/en not_active Expired - Fee Related
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