JP2016503159A5 - - Google Patents

Download PDF

Info

Publication number
JP2016503159A5
JP2016503159A5 JP2015547053A JP2015547053A JP2016503159A5 JP 2016503159 A5 JP2016503159 A5 JP 2016503159A5 JP 2015547053 A JP2015547053 A JP 2015547053A JP 2015547053 A JP2015547053 A JP 2015547053A JP 2016503159 A5 JP2016503159 A5 JP 2016503159A5
Authority
JP
Japan
Prior art keywords
target substance
2bound
magnetic nanoparticles
bound
biological sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015547053A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016503159A (ja
JP6371303B2 (ja
Filing date
Publication date
Priority claimed from GB201301992A external-priority patent/GB201301992D0/en
Application filed filed Critical
Priority claimed from PCT/EP2013/076569 external-priority patent/WO2014095645A1/en
Publication of JP2016503159A publication Critical patent/JP2016503159A/ja
Publication of JP2016503159A5 publication Critical patent/JP2016503159A5/ja
Application granted granted Critical
Publication of JP6371303B2 publication Critical patent/JP6371303B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015547053A 2012-12-17 2013-12-13 目標物質のインビトロ磁気共鳴検出 Expired - Fee Related JP6371303B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN3886/DEL/2012 2012-12-17
IN3886DE2012 2012-12-17
GB201301992A GB201301992D0 (en) 2013-02-05 2013-02-05 In-vitro magnetic resonance detection of a target substance
GB1301992.2 2013-02-05
PCT/EP2013/076569 WO2014095645A1 (en) 2012-12-17 2013-12-13 In-vitro magnetic resonance detection of a target substance

Publications (3)

Publication Number Publication Date
JP2016503159A JP2016503159A (ja) 2016-02-01
JP2016503159A5 true JP2016503159A5 (enExample) 2017-01-26
JP6371303B2 JP6371303B2 (ja) 2018-08-08

Family

ID=49759340

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015547053A Expired - Fee Related JP6371303B2 (ja) 2012-12-17 2013-12-13 目標物質のインビトロ磁気共鳴検出

Country Status (5)

Country Link
US (1) US10156567B2 (enExample)
EP (1) EP2932289A1 (enExample)
JP (1) JP6371303B2 (enExample)
CN (1) CN104871026B (enExample)
WO (1) WO2014095645A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6244289B2 (ja) * 2014-10-29 2017-12-06 学校法人 神野学園 クドア・セプテンプンクタータの検出方法
CN109477873A (zh) 2016-07-21 2019-03-15 西门子医疗保健诊断公司 用于ivd自动化系统的磁屏蔽
CN107478834A (zh) * 2017-09-05 2017-12-15 杨蕾 一种检测沙门氏菌磁共振成像试剂盒的制备方法
EP3575813B1 (en) * 2018-05-30 2022-06-29 Siemens Healthcare GmbH Quantitative mapping of a magnetic resonance imaging parameter by data-driven signal-model learning
CN109658468B (zh) * 2018-12-12 2022-12-13 深圳先进技术研究院 磁共振参数成像方法、装置、设备及存储介质
EP4047356A4 (en) * 2019-10-17 2023-11-22 Riken DETECTION METHOD AND SYSTEM FOR DETECTION OF MASTITIS IN A DOMESTIC ANIMAL
IL295143B2 (en) * 2020-02-13 2026-02-01 Hoffmann La Roche A method for determining the loading state of AAV particles using nuclear magnetic resonance relaxometry
CN112611868A (zh) * 2020-12-18 2021-04-06 厦门大学 一种用于磁共振分析方法检测新型冠状病毒的探针及其制备方法
EP4423520A4 (en) * 2021-10-28 2025-09-03 Massachusetts Inst Technology MAGNETIC RESONANCE MICRORELAXOMETRY (MMRR) FOR RAPID AND NON-INVASIVE DETECTION OF SENESCENCE IN MESENCHYMAL STEM CELLS
EP4732029A1 (en) * 2023-06-20 2026-04-29 Regents of the University of Michigan Methods for magnetic resonance molecular imaging of nanoconstructs and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030028093A1 (en) * 2001-04-20 2003-02-06 Yong Ke Exponential decay modeling in spectroscopy
US7088102B1 (en) 2005-03-03 2006-08-08 Varian, Inc. Rapid sample multiplexing
US7781228B2 (en) 2005-04-07 2010-08-24 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
EP1880228B1 (en) 2005-05-09 2011-07-06 The General Hospital Corporation Water relaxation-based sensors
US7560289B2 (en) * 2005-11-16 2009-07-14 Chin-Yih Rex Hong Methods of quantitatively measuring biomolecules
US20070166730A1 (en) 2006-01-19 2007-07-19 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
DE102007009494A1 (de) * 2007-02-27 2008-08-28 Bayer Healthcare Ag Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
US8421458B2 (en) * 2007-09-28 2013-04-16 T2 Biosystems, Inc. NMR diagnostics by means of a plastic sample container
WO2009045551A1 (en) * 2007-10-04 2009-04-09 The General Hospital Corporation Miniaturized magnetic resonance systems and methods
DE102007049701B4 (de) 2007-10-17 2010-09-23 Bruker Biospin Ag NMR-Messkopf mit mehreren Resonatorsystemen zur simultanen Vermessung mehrerer Messproben in einem gekoppelten Mode
AU2008325088A1 (en) * 2007-11-06 2009-05-14 T2 Biosystems, Inc. Small magnet and RF coil for magnetic resonance relaxometry
EP2905631A1 (en) * 2007-12-21 2015-08-12 T2 Biosystems, Inc. Magnetic resonance system with implantable components and methods of use thereof
BRPI1006278A2 (pt) * 2009-03-25 2017-05-30 Koninklijke Emballage Ind Van Leer B V metodo para avaliação quantitativa de celulas marcadas por agente magnetico em um paciente meio de armazenamento digital e sistema para avaliação quantitativa de celulas marcadas por agente magnetico em um paciente
DE102010013900B4 (de) * 2010-04-01 2013-01-03 Hochschule Für Angewandte Wissenschaften Fachhochschule Würzburg-Schweinfurt Verfahren zur Bildgebung mittels magnetischer Kleinstpartikel sowie Vorrichtung hierfür
US20110262989A1 (en) 2010-04-21 2011-10-27 Nanomr, Inc. Isolating a target analyte from a body fluid
WO2012044387A2 (en) 2010-07-06 2012-04-05 T2 Biosystems, Inc. Methods and compositions for detection of analytes
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8409807B2 (en) * 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
CA2815085C (en) * 2010-10-22 2022-06-21 T2 Biosystems, Inc. Nmr systems and methods for the rapid detection of analytes
WO2012129281A2 (en) * 2011-03-22 2012-09-27 The General Hospital Corporation Detection of targets using magnetic resonance
CA2841484A1 (en) * 2011-07-13 2013-01-17 T2 Biosystems, Inc. Nmr methods for monitoring blood clot formation
JP5879189B2 (ja) 2012-04-26 2016-03-08 株式会社日立製作所 交流磁場を用いた磁気的免疫検査方法及び検査装置
CN103760186A (zh) 2012-09-13 2014-04-30 阿斯派克影像有限公司 用于体外诊断应用的使用顺磁剂的工具和方法
CN104614513B (zh) * 2015-01-26 2016-05-25 国家纳米科学中心 一种基于磁分离的弛豫时间免疫传感分析方法
CN105920620A (zh) * 2016-06-21 2016-09-07 东南大学 磁性荧光多模态纳米生物探针及其制备方法和应用

Similar Documents

Publication Publication Date Title
Jiang et al. Quantification of cell size using temporal diffusion spectroscopy
Birkl et al. Effects of formalin fixation and temperature on MR relaxation times in the human brain
Zhang et al. Assignment of the molecular origins of CEST signals at 2 ppm in rat brain
Vallurupalli et al. Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer
Goerke et al. Signature of protein unfolding in chemical exchange saturation transfer imaging
Šala et al. Gelatin gels as multi-element calibration standards in LA-ICP-MS bioimaging: fabrication of homogeneous standards and microhomogeneity testing
Li et al. Time‐dependent influence of cell membrane permeability on MR diffusion measurements
Peng et al. Nuclear magnetic resonance-based approaches for lead generation in drug discovery
Dixon et al. A multislice gradient echo pulse sequence for CEST imaging
CN102507627B (zh) 一种高通量筛选药物的核磁共振方法
US20180372810A1 (en) Magnetic Sensor Device, Self-Calibration Methods And Current Sensor
MX362703B (es) Clasificación de alto rendimiento de objetos pequeños a través del contenido de aceite y/o humedad usando resonancia magnética nuclear de campo bajo.
Yulikov Spectroscopically orthogonal spin labels and distance measurements in biomolecules
US20180284127A1 (en) Method and apparatus for analyzing protein-protein interaction on single-molecule level within the cellular environment
JP2017173334A5 (enExample)
US10620205B2 (en) NMR methods for endotoxin analysis
CN104094105A (zh) 核磁共振成像装置以及核磁共振成像方法
US20170212063A1 (en) Composite FID-CPMG Process for Fast Relaxing Media Determination
Hulsey et al. 1H MRS characterization of neurochemical profiles in orthotopic mouse models of human brain tumors
Ghosh et al. Quantitative metabolic profiling of NMR spectral signatures of branched chain amino acids in blood serum
Śledź et al. Ligand‐observed NMR in fragment‐based approaches
JP2005345193A (ja) 核磁気共鳴法及び／又は核磁気共鳴による拡散係数測定法を用いた定量方法
Velasco Gonzalez et al. Making acute ischemic stroke thrombi visible in MRI imaging
Janowska et al. Intermolecular paramagnetic relaxation enhancement (pre) studies of transient complexes in intrinsically disordered proteins
Ando et al. Quantification of molecules in 1H-NMR metabolomics with formate as a concentration standard