JP2017173334A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017173334A5 JP2017173334A5 JP2017092161A JP2017092161A JP2017173334A5 JP 2017173334 A5 JP2017173334 A5 JP 2017173334A5 JP 2017092161 A JP2017092161 A JP 2017092161A JP 2017092161 A JP2017092161 A JP 2017092161A JP 2017173334 A5 JP2017173334 A5 JP 2017173334A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- fluorouracil
- specimen
- cancer
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003839 salts Chemical class 0.000 claims 10
- GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical compound FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 claims 5
- 239000002246 antineoplastic agent Substances 0.000 claims 5
- 229960002949 fluorouracil Drugs 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- DWAFYCQODLXJNR-BNTLRKBRSA-L oxaliplatin Chemical compound O1C(=O)C(=O)O[Pt]11N[C@@H]2CCCC[C@H]2N1 DWAFYCQODLXJNR-BNTLRKBRSA-L 0.000 claims 5
- 229960001756 oxaliplatin Drugs 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 239000012472 biological sample Substances 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 230000035945 sensitivity Effects 0.000 claims 3
- OYIFNHCXNCRBQI-UHFFFAOYSA-N 2-aminoadipic acid Chemical compound OC(=O)C(N)CCCC(O)=O OYIFNHCXNCRBQI-UHFFFAOYSA-N 0.000 claims 2
- NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- MIKUYHXYGGJMLM-GIMIYPNGSA-N Crotonoside Natural products C1=NC2=C(N)NC(=O)N=C2N1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O MIKUYHXYGGJMLM-GIMIYPNGSA-N 0.000 claims 1
- NYHBQMYGNKIUIF-UHFFFAOYSA-N D-guanosine Natural products C1=2NC(N)=NC(=O)C=2N=CN1C1OC(CO)C(O)C1O NYHBQMYGNKIUIF-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229960003180 glutathione Drugs 0.000 claims 1
- 229940029575 guanosine Drugs 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012037448 | 2012-02-23 | ||
| JP2012037448 | 2012-02-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014500945A Division JP6141824B2 (ja) | 2012-02-23 | 2013-02-22 | 併用抗がん剤の感受性判定マーカー |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018140929A Division JP2018169409A (ja) | 2012-02-23 | 2018-07-27 | 併用抗がん剤の感受性判定マーカー |
| JP2018140928A Division JP6527994B2 (ja) | 2012-02-23 | 2018-07-27 | 併用抗がん剤の感受性判定マーカー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017173334A JP2017173334A (ja) | 2017-09-28 |
| JP2017173334A5 true JP2017173334A5 (enExample) | 2017-11-16 |
| JP6381735B2 JP6381735B2 (ja) | 2018-08-29 |
Family
ID=49005852
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014500945A Expired - Fee Related JP6141824B2 (ja) | 2012-02-23 | 2013-02-22 | 併用抗がん剤の感受性判定マーカー |
| JP2017092161A Expired - Fee Related JP6381735B2 (ja) | 2012-02-23 | 2017-05-08 | 併用抗がん剤の感受性判定マーカー |
| JP2018140928A Expired - Fee Related JP6527994B2 (ja) | 2012-02-23 | 2018-07-27 | 併用抗がん剤の感受性判定マーカー |
| JP2018140929A Ceased JP2018169409A (ja) | 2012-02-23 | 2018-07-27 | 併用抗がん剤の感受性判定マーカー |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014500945A Expired - Fee Related JP6141824B2 (ja) | 2012-02-23 | 2013-02-22 | 併用抗がん剤の感受性判定マーカー |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018140928A Expired - Fee Related JP6527994B2 (ja) | 2012-02-23 | 2018-07-27 | 併用抗がん剤の感受性判定マーカー |
| JP2018140929A Ceased JP2018169409A (ja) | 2012-02-23 | 2018-07-27 | 併用抗がん剤の感受性判定マーカー |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9733256B2 (enExample) |
| EP (3) | EP2818870A4 (enExample) |
| JP (4) | JP6141824B2 (enExample) |
| CN (2) | CN108508168B (enExample) |
| WO (1) | WO2013125675A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107252428B (zh) * | 2011-03-24 | 2020-04-14 | 学校法人庆应义塾 | 抗癌剂感受性的判定标记 |
| CN108508168B (zh) | 2012-02-23 | 2021-08-17 | 学校法人庆应义塾 | 并用抗癌剂的感受性判定标记 |
| JPWO2016031816A1 (ja) * | 2014-08-26 | 2017-06-15 | 学校法人慶應義塾 | 抗がん剤の感受性の判定マーカー |
| CN116148481A (zh) * | 2017-03-31 | 2023-05-23 | 学校法人庆应义塾 | 并用抗癌剂的感受性判定标记 |
| WO2019188446A1 (ja) | 2018-03-29 | 2019-10-03 | 学校法人慶應義塾 | イリノテカンを含む抗がん剤療法の感受性判定マーカー |
| WO2020067228A1 (ja) | 2018-09-28 | 2020-04-02 | 学校法人慶應義塾 | 併用抗がん剤の感受性の判定マーカー |
| EP4237090B1 (en) * | 2020-10-29 | 2026-02-18 | Board of Regents, The University of Texas System | Methods for the detection and treatment of ovarian cancer |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100569288C (zh) * | 2005-04-06 | 2009-12-16 | 山东蓝金生物工程有限公司 | 一种抗实体肿瘤药物组合物 |
| DE102005051976B4 (de) * | 2005-10-31 | 2009-04-30 | Forschungszentrum Borstel Zentrum für Medizin und Biowissenschaften | Kit für hoch-sensitive Nachweisassays |
| AU2007299846B2 (en) | 2006-09-19 | 2014-11-20 | Metabolon, Inc. | Biomarkers for prostate cancer and methods using the same |
| CN101932338A (zh) * | 2008-01-31 | 2010-12-29 | 学校法人庆应义墪 | 抗癌剂感受性的判定方法 |
| US8945929B2 (en) | 2008-01-31 | 2015-02-03 | Keio University | Marker for determination of sensitivity to anti-cancer agent |
| JP2010038796A (ja) * | 2008-08-06 | 2010-02-18 | Human Metabolome Technologies Inc | 疾患マーカー、および、疾患マーカーの測定方法 |
| EP2495569B1 (en) * | 2009-10-30 | 2016-06-15 | Keio University | Method for determination of sensitivity to anti-cancer agent |
| US8809362B2 (en) * | 2009-10-30 | 2014-08-19 | Keio University | Anticancer agent sensitivity-determining marker |
| JP2013515270A (ja) * | 2009-12-22 | 2013-05-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 前立腺癌の代謝学的プロファイリング |
| CN108508168B (zh) | 2012-02-23 | 2021-08-17 | 学校法人庆应义塾 | 并用抗癌剂的感受性判定标记 |
-
2013
- 2013-02-22 CN CN201810228371.3A patent/CN108508168B/zh not_active Expired - Fee Related
- 2013-02-22 EP EP13752246.2A patent/EP2818870A4/en not_active Withdrawn
- 2013-02-22 JP JP2014500945A patent/JP6141824B2/ja not_active Expired - Fee Related
- 2013-02-22 EP EP17202053.9A patent/EP3326632B1/en active Active
- 2013-02-22 US US14/379,945 patent/US9733256B2/en not_active Expired - Fee Related
- 2013-02-22 EP EP20214606.4A patent/EP3812009A1/en not_active Withdrawn
- 2013-02-22 CN CN201380010388.7A patent/CN104169721A/zh active Pending
- 2013-02-22 WO PCT/JP2013/054488 patent/WO2013125675A1/ja not_active Ceased
-
2017
- 2017-05-08 JP JP2017092161A patent/JP6381735B2/ja not_active Expired - Fee Related
- 2017-06-28 US US15/635,293 patent/US10481160B2/en active Active
-
2018
- 2018-07-27 JP JP2018140928A patent/JP6527994B2/ja not_active Expired - Fee Related
- 2018-07-27 JP JP2018140929A patent/JP2018169409A/ja not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2016046640A3 (en) | Methods for predicting drug responsiveness | |
| Sarzosa et al. | J–CTOD relations in clamped SE (T) fracture specimens including 3-D stationary and growth analysis | |
| PH12018550037A1 (en) | Quencher containing water-soluble polymer-conjugated nanomaterial and use thereof | |
| EA201992252A1 (ru) | Логометрические способы визуализации флуоресценции | |
| EP3320900A3 (en) | Marker for determination of sensitivity to anticancer agent | |
| EP3583214A4 (en) | METHODS AND COMPOSITIONS FOR IDENTIFYING OR QUANTIFYING TARGETS IN A BIOLOGICAL SAMPLE | |
| EP4286055C0 (en) | METHOD FOR DETERMINING THE PRESENCE OF MULTIPLE FORMS OF A NUCLEIC ACID ANALYTE IN A SAMPLE | |
| EP3350579C0 (en) | MEASUREMENT OF ANALYTE CONCENTRATION IN LIQUID SAMPLES BY SURFACE-ENHANCED RAMAN SPECTROSCOPY | |
| JP2016500110A5 (enExample) | ||
| EP4656740A3 (en) | Breast cancer detection kit or device, and detection method | |
| MY187050A (en) | Cancer cell-specific antibody, anticancer agent, and cancer testing method | |
| EP4418274A3 (en) | Applications of plasma mitochondrial dna analysis | |
| MX380642B (es) | Ceramidas y su uso en el diagnostico de enfermedad cardiovascular (ecv). | |
| Alépée et al. | Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro reconstructed human tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals | |
| MX2024014862A (es) | Metodos y composiciones para revertir la acumulacion de plaquetas | |
| WO2016025382A3 (en) | Probes for quantitative imaging of thiols in various environments | |
| EP3486652C0 (en) | METHOD FOR IDENTIFYING A BIOLOGICAL SAMPLE OF A MAMMAL, COMPOSITION FOR USE IN THIS METHOD AND KIT FOR CARRYING OUT THIS METHOD | |
| ATE468535T1 (de) | Verwendung von nnmt als marker für lungenkrebs | |
| AR077206A1 (es) | Metodo de cuantificacion de la absorcion de nanoparticulas magneticas en tejidos animales, y equipo para realizarlo | |
| SG10201610586QA (en) | Dynamic Light Scattering Nanoplatform For High-Throughput Transcription Factor-DNA Interaction Determination For Drug And/Or Disease Screening | |
| WO2015091963A3 (en) | Determination of platelet-mirnas in acute myocardial infarction | |
| EP3679353C0 (de) | Aerosolpartikelmessgerät zur bestimmung von materialien in echtzeit mittels fluoreszenzlebenszeit messung im frequenzbereich | |
| WO2014151079A8 (en) | Ratio based biomarkers and methods of use thereof for the detection and prognosis of cancer | |
| EP3698128C0 (en) | ELECTROANALYTICAL INSTRUMENT FOR DETERMINING BY AMPEROMETRY THE PRESENCE OR QUANTITY OF AN ANALYTE IN AN AQUEOUS SAMPLE | |
| Shlush et al. | Digital image analysis of cells stained with the senescence-associated β-galactosidase assay |