JP6371303B2 - 目標物質のインビトロ磁気共鳴検出 - Google Patents

目標物質のインビトロ磁気共鳴検出 Download PDF

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Publication number
JP6371303B2
JP6371303B2 JP2015547053A JP2015547053A JP6371303B2 JP 6371303 B2 JP6371303 B2 JP 6371303B2 JP 2015547053 A JP2015547053 A JP 2015547053A JP 2015547053 A JP2015547053 A JP 2015547053A JP 6371303 B2 JP6371303 B2 JP 6371303B2
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Japan
Prior art keywords
target substance
2bound
magnetic nanoparticles
2free
sample
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Expired - Fee Related
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JP2015547053A
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Japanese (ja)
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JP2016503159A (ja
JP2016503159A5 (enExample
Inventor
ヴェンカテサン，ラメシュ
バラシュブラマニアン，アルン
アトレッヤ，チャンダン・ラマスワミィ
ヘッジ，ラヴィ
ムクハージェ，リティカ・アッパル
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General Electric Co
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General Electric Co
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Priority claimed from GB201301992A external-priority patent/GB201301992D0/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/448—Relaxometry, i.e. quantification of relaxation times or spin density
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/465—NMR spectroscopy applied to biological material, e.g. in vitro testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/32—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Bacillus (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2015547053A 2012-12-17 2013-12-13 目標物質のインビトロ磁気共鳴検出 Expired - Fee Related JP6371303B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN3886/DEL/2012 2012-12-17
IN3886DE2012 2012-12-17
GB201301992A GB201301992D0 (en) 2013-02-05 2013-02-05 In-vitro magnetic resonance detection of a target substance
GB1301992.2 2013-02-05
PCT/EP2013/076569 WO2014095645A1 (en) 2012-12-17 2013-12-13 In-vitro magnetic resonance detection of a target substance

Publications (3)

Publication Number Publication Date
JP2016503159A JP2016503159A (ja) 2016-02-01
JP2016503159A5 JP2016503159A5 (enExample) 2017-01-26
JP6371303B2 true JP6371303B2 (ja) 2018-08-08

Family

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Family Applications (1)

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JP2015547053A Expired - Fee Related JP6371303B2 (ja) 2012-12-17 2013-12-13 目標物質のインビトロ磁気共鳴検出

Country Status (5)

Country Link
US (1) US10156567B2 (enExample)
EP (1) EP2932289A1 (enExample)
JP (1) JP6371303B2 (enExample)
CN (1) CN104871026B (enExample)
WO (1) WO2014095645A1 (enExample)

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JP6244289B2 (ja) * 2014-10-29 2017-12-06 学校法人 神野学園 クドア・セプテンプンクタータの検出方法
JP6915949B2 (ja) 2016-07-21 2021-08-11 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． Ｉｖｄオートメーションシステムのための磁気シールド
CN107478834A (zh) * 2017-09-05 2017-12-15 杨蕾 一种检测沙门氏菌磁共振成像试剂盒的制备方法
EP3575813B1 (en) * 2018-05-30 2022-06-29 Siemens Healthcare GmbH Quantitative mapping of a magnetic resonance imaging parameter by data-driven signal-model learning
CN109658468B (zh) * 2018-12-12 2022-12-13 深圳先进技术研究院 磁共振参数成像方法、装置、设备及存储介质
JP7550407B2 (ja) * 2019-10-17 2024-09-13 国立研究開発法人理化学研究所 家畜の乳房炎の検査方法及び検査システム
IL295143B2 (en) * 2020-02-13 2026-02-01 Hoffmann La Roche A method for determining the loading state of AAV particles using nuclear magnetic resonance relaxometry
CN112611868A (zh) * 2020-12-18 2021-04-06 厦门大学 一种用于磁共振分析方法检测新型冠状病毒的探针及其制备方法
WO2023076447A1 (en) * 2021-10-28 2023-05-04 Massachusetts Institute Of Technology Micro magnetic resonance relaxometry (μmrr) for rapid and non-invasive detection of senescence in mesenchymal stem cells
WO2024263744A1 (en) * 2023-06-20 2024-12-26 Regents Of The University Of Michigan Methods for magnetic resonance molecular imaging of nanoconstructs and uses thereof

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US7088102B1 (en) 2005-03-03 2006-08-08 Varian, Inc. Rapid sample multiplexing
US7781228B2 (en) 2005-04-07 2010-08-24 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
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US7560289B2 (en) * 2005-11-16 2009-07-14 Chin-Yih Rex Hong Methods of quantitatively measuring biomolecules
US20070166730A1 (en) 2006-01-19 2007-07-19 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
DE102007009494A1 (de) * 2007-02-27 2008-08-28 Bayer Healthcare Ag Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
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JP2011508213A (ja) * 2007-12-21 2011-03-10 ティツー・バイオシステムズ・インコーポレーテッド 埋め込み可能な構成品を備えた磁気共鳴システムおよびその使用方法
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DE102010013900B4 (de) * 2010-04-01 2013-01-03 Hochschule Für Angewandte Wissenschaften Fachhochschule Würzburg-Schweinfurt Verfahren zur Bildgebung mittels magnetischer Kleinstpartikel sowie Vorrichtung hierfür
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CN105920620A (zh) * 2016-06-21 2016-09-07 东南大学 磁性荧光多模态纳米生物探针及其制备方法和应用

Also Published As

Publication number Publication date
CN104871026B (zh) 2020-01-10
EP2932289A1 (en) 2015-10-21
JP2016503159A (ja) 2016-02-01
US20160195526A1 (en) 2016-07-07
US10156567B2 (en) 2018-12-18
WO2014095645A1 (en) 2014-06-26
CN104871026A (zh) 2015-08-26

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