JP2016501211A - 三環性インドールを得るためのハロゲン化亜鉛による環化プロセス - Google Patents
三環性インドールを得るためのハロゲン化亜鉛による環化プロセス Download PDFInfo
- Publication number
- JP2016501211A JP2016501211A JP2015544484A JP2015544484A JP2016501211A JP 2016501211 A JP2016501211 A JP 2016501211A JP 2015544484 A JP2015544484 A JP 2015544484A JP 2015544484 A JP2015544484 A JP 2015544484A JP 2016501211 A JP2016501211 A JP 2016501211A
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- aryl
- formula
- alkylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3690/DEL/2012 | 2012-11-30 | ||
| IN3690DE2012 | 2012-11-30 | ||
| GB1300649.9 | 2013-01-15 | ||
| GB201300649A GB201300649D0 (en) | 2013-01-15 | 2013-01-15 | Cyclization |
| PCT/EP2013/075107 WO2014083163A1 (en) | 2012-11-30 | 2013-11-29 | Zinc halide mediated cyclization process leading to tricyclic indoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016501211A true JP2016501211A (ja) | 2016-01-18 |
| JP2016501211A5 JP2016501211A5 (enExample) | 2017-01-12 |
Family
ID=49681038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015544484A Pending JP2016501211A (ja) | 2012-11-30 | 2013-11-29 | 三環性インドールを得るためのハロゲン化亜鉛による環化プロセス |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9475769B2 (enExample) |
| EP (1) | EP2925723A1 (enExample) |
| JP (1) | JP2016501211A (enExample) |
| KR (1) | KR20150088803A (enExample) |
| CN (1) | CN104797559A (enExample) |
| AU (1) | AU2013351126B2 (enExample) |
| BR (1) | BR112015012401A2 (enExample) |
| CA (1) | CA2889642A1 (enExample) |
| IN (1) | IN2015DN03939A (enExample) |
| MX (1) | MX2015006864A (enExample) |
| RU (1) | RU2647867C2 (enExample) |
| WO (1) | WO2014083163A1 (enExample) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11322713A (ja) * | 1998-04-17 | 1999-11-24 | Eli Lilly & Co | 置換三環式化合物 |
| JP2005527466A (ja) * | 2001-08-09 | 2005-09-15 | イーライ・リリー・アンド・カンパニー | ｓＰＬＡ２インヒビターとしてのシクロヘプトＢインドール誘導体 |
| JP2012521973A (ja) * | 2009-03-27 | 2012-09-20 | ジーイー・ヘルスケア・リミテッド | Ｐｂｒリガンドとしての三環系インドール誘導体 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2310250A1 (en) | 1997-11-14 | 1999-05-27 | August Masaru Watanabe | Treatment for alzheimer's disease |
| US7160909B2 (en) | 2001-08-09 | 2007-01-09 | Eli Lilly And Company | Cyclopenta[b]indole derivatives as sPLA2 inhibitors |
-
2013
- 2013-11-29 IN IN3939DEN2015 patent/IN2015DN03939A/en unknown
- 2013-11-29 JP JP2015544484A patent/JP2016501211A/ja active Pending
- 2013-11-29 US US14/648,618 patent/US9475769B2/en not_active Expired - Fee Related
- 2013-11-29 CA CA2889642A patent/CA2889642A1/en not_active Abandoned
- 2013-11-29 RU RU2015118221A patent/RU2647867C2/ru not_active IP Right Cessation
- 2013-11-29 AU AU2013351126A patent/AU2013351126B2/en not_active Ceased
- 2013-11-29 MX MX2015006864A patent/MX2015006864A/es unknown
- 2013-11-29 CN CN201380062464.9A patent/CN104797559A/zh active Pending
- 2013-11-29 EP EP13798661.8A patent/EP2925723A1/en not_active Ceased
- 2013-11-29 WO PCT/EP2013/075107 patent/WO2014083163A1/en not_active Ceased
- 2013-11-29 BR BR112015012401A patent/BR112015012401A2/pt not_active IP Right Cessation
- 2013-11-29 KR KR1020157013976A patent/KR20150088803A/ko not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11322713A (ja) * | 1998-04-17 | 1999-11-24 | Eli Lilly & Co | 置換三環式化合物 |
| JP2005527466A (ja) * | 2001-08-09 | 2005-09-15 | イーライ・リリー・アンド・カンパニー | ｓＰＬＡ２インヒビターとしてのシクロヘプトＢインドール誘導体 |
| JP2012521973A (ja) * | 2009-03-27 | 2012-09-20 | ジーイー・ヘルスケア・リミテッド | Ｐｂｒリガンドとしての三環系インドール誘導体 |
Non-Patent Citations (1)
| Title |
|---|
| WADSWORTH, HARRY ET AL.: "[18F]GE-180: A novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO)", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22(3), JPN6017042670, 2012, pages 1308 - 1313, ISSN: 0003749208 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014083163A1 (en) | 2014-06-05 |
| US20150336891A1 (en) | 2015-11-26 |
| CA2889642A1 (en) | 2014-06-05 |
| IN2015DN03939A (enExample) | 2015-10-02 |
| RU2015118221A (ru) | 2017-01-11 |
| EP2925723A1 (en) | 2015-10-07 |
| MX2015006864A (es) | 2015-09-16 |
| AU2013351126A1 (en) | 2015-05-21 |
| AU2013351126B2 (en) | 2017-12-14 |
| CN104797559A (zh) | 2015-07-22 |
| BR112015012401A2 (pt) | 2019-10-01 |
| KR20150088803A (ko) | 2015-08-03 |
| RU2647867C2 (ru) | 2018-03-21 |
| US9475769B2 (en) | 2016-10-25 |
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