CA2889642A1 - Zinc halide mediated cyclization process leading to tricyclic indoles - Google Patents

Zinc halide mediated cyclization process leading to tricyclic indoles Download PDF

Info

Publication number
CA2889642A1
CA2889642A1 CA2889642A CA2889642A CA2889642A1 CA 2889642 A1 CA2889642 A1 CA 2889642A1 CA 2889642 A CA2889642 A CA 2889642A CA 2889642 A CA2889642 A CA 2889642A CA 2889642 A1 CA2889642 A1 CA 2889642A1
Authority
CA
Canada
Prior art keywords
group
alkyl
aryl
formula
alkylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2889642A
Other languages
English (en)
French (fr)
Inventor
Sondre NILSEN
Umamaheshwar P. MOKKAPATI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201300649A external-priority patent/GB201300649D0/en
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of CA2889642A1 publication Critical patent/CA2889642A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA2889642A 2012-11-30 2013-11-29 Zinc halide mediated cyclization process leading to tricyclic indoles Abandoned CA2889642A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN3690/DEL/2012 2012-11-30
IN3690DE2012 2012-11-30
GB1300649.9 2013-01-15
GB201300649A GB201300649D0 (en) 2013-01-15 2013-01-15 Cyclization
PCT/EP2013/075107 WO2014083163A1 (en) 2012-11-30 2013-11-29 Zinc halide mediated cyclization process leading to tricyclic indoles

Publications (1)

Publication Number Publication Date
CA2889642A1 true CA2889642A1 (en) 2014-06-05

Family

ID=49681038

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2889642A Abandoned CA2889642A1 (en) 2012-11-30 2013-11-29 Zinc halide mediated cyclization process leading to tricyclic indoles

Country Status (12)

Country Link
US (1) US9475769B2 (enExample)
EP (1) EP2925723A1 (enExample)
JP (1) JP2016501211A (enExample)
KR (1) KR20150088803A (enExample)
CN (1) CN104797559A (enExample)
AU (1) AU2013351126B2 (enExample)
BR (1) BR112015012401A2 (enExample)
CA (1) CA2889642A1 (enExample)
IN (1) IN2015DN03939A (enExample)
MX (1) MX2015006864A (enExample)
RU (1) RU2647867C2 (enExample)
WO (1) WO2014083163A1 (enExample)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2310250A1 (en) 1997-11-14 1999-05-27 August Masaru Watanabe Treatment for alzheimer's disease
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.
US7160909B2 (en) 2001-08-09 2007-01-09 Eli Lilly And Company Cyclopenta[b]indole derivatives as sPLA2 inhibitors
ATE312817T1 (de) 2001-08-09 2005-12-15 Lilly Co Eli Cyclohept'bö indolderivate als spla2-inhibitoren
GB0905328D0 (en) 2009-03-27 2009-05-13 Ge Healthcare Ltd Indole derivatives

Also Published As

Publication number Publication date
WO2014083163A1 (en) 2014-06-05
US20150336891A1 (en) 2015-11-26
IN2015DN03939A (enExample) 2015-10-02
RU2015118221A (ru) 2017-01-11
EP2925723A1 (en) 2015-10-07
JP2016501211A (ja) 2016-01-18
MX2015006864A (es) 2015-09-16
AU2013351126A1 (en) 2015-05-21
AU2013351126B2 (en) 2017-12-14
CN104797559A (zh) 2015-07-22
BR112015012401A2 (pt) 2019-10-01
KR20150088803A (ko) 2015-08-03
RU2647867C2 (ru) 2018-03-21
US9475769B2 (en) 2016-10-25

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20181114

FZDE Discontinued

Effective date: 20210831