JP2016040307A5 - - Google Patents
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- Publication number
- JP2016040307A5 JP2016040307A5 JP2015214268A JP2015214268A JP2016040307A5 JP 2016040307 A5 JP2016040307 A5 JP 2016040307A5 JP 2015214268 A JP2015214268 A JP 2015214268A JP 2015214268 A JP2015214268 A JP 2015214268A JP 2016040307 A5 JP2016040307 A5 JP 2016040307A5
- Authority
- JP
- Japan
- Prior art keywords
- swelling agent
- coating
- suspension
- drug delivery
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 239000011248 coating agent Substances 0.000 claims 11
- 238000000576 coating method Methods 0.000 claims 11
- 230000008961 swelling Effects 0.000 claims 10
- 239000000725 suspension Substances 0.000 claims 7
- 239000000463 material Substances 0.000 claims 6
- 239000011247 coating layer Substances 0.000 claims 5
- 238000012377 drug delivery Methods 0.000 claims 5
- 239000013543 active substance Substances 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 4
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- 239000000758 substrate Substances 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 2
- 230000000996 additive effect Effects 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 239000005557 antagonist Substances 0.000 claims 2
- 229920002301 cellulose acetate Polymers 0.000 claims 2
- 210000001072 colon Anatomy 0.000 claims 2
- 210000001198 duodenum Anatomy 0.000 claims 2
- 229940088597 hormone Drugs 0.000 claims 2
- 239000005556 hormone Substances 0.000 claims 2
- 230000002163 immunogen Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000002858 neurotransmitter agent Substances 0.000 claims 2
- 239000004014 plasticizer Substances 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 239000008109 sodium starch glycolate Substances 0.000 claims 2
- 229940079832 sodium starch glycolate Drugs 0.000 claims 2
- 229920003109 sodium starch glycolate Polymers 0.000 claims 2
- 230000003637 steroidlike Effects 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 239000001069 triethyl citrate Substances 0.000 claims 2
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 claims 2
- 235000013769 triethyl citrate Nutrition 0.000 claims 2
- 125000005591 trimellitate group Chemical group 0.000 claims 2
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 1
- 229920003134 Eudragit® polymer Polymers 0.000 claims 1
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical group OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 claims 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- SBNPWPIBESPSIF-MHWMIDJBSA-N cetrorelix Chemical group C([C@@H](C(=O)N[C@H](CCCNC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](C)C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](CC=1C=NC=CC=1)NC(=O)[C@@H](CC=1C=CC(Cl)=CC=1)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(C)=O)C1=CC=C(O)C=C1 SBNPWPIBESPSIF-MHWMIDJBSA-N 0.000 claims 1
- 229960003230 cetrorelix Drugs 0.000 claims 1
- 108700008462 cetrorelix Proteins 0.000 claims 1
- 238000013270 controlled release Methods 0.000 claims 1
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 claims 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 claims 1
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 claims 1
- 230000000968 intestinal effect Effects 0.000 claims 1
- 238000002386 leaching Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 229940100467 polyvinyl acetate phthalate Drugs 0.000 claims 1
- 230000000541 pulsatile effect Effects 0.000 claims 1
- 229940116351 sebacate Drugs 0.000 claims 1
- CXMXRPHRNRROMY-UHFFFAOYSA-L sebacate(2-) Chemical compound [O-]C(=O)CCCCCCCCC([O-])=O CXMXRPHRNRROMY-UHFFFAOYSA-L 0.000 claims 1
- 239000011877 solvent mixture Substances 0.000 claims 1
- 238000005507 spraying Methods 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015214268A JP6454630B2 (ja) | 2015-10-30 | 2015-10-30 | ｐＨ制御パルス送達システム、その調製法及び使用法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015214268A JP6454630B2 (ja) | 2015-10-30 | 2015-10-30 | ｐＨ制御パルス送達システム、その調製法及び使用法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014049670A Division JP2014139210A (ja) | 2014-03-13 | 2014-03-13 | ｐＨ制御パルス送達システム、その調製法及び使用法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017136280A Division JP2017203031A (ja) | 2017-07-12 | 2017-07-12 | ｐＨ制御パルス送達システム、その調製法及び使用法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016040307A JP2016040307A (ja) | 2016-03-24 |
| JP2016040307A5 true JP2016040307A5 (enrdf_load_stackoverflow) | 2016-09-15 |
| JP6454630B2 JP6454630B2 (ja) | 2019-01-16 |
Family
ID=55540767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015214268A Expired - Lifetime JP6454630B2 (ja) | 2015-10-30 | 2015-10-30 | ｐＨ制御パルス送達システム、その調製法及び使用法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6454630B2 (enrdf_load_stackoverflow) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61100526A (ja) * | 1984-10-22 | 1986-05-19 | Kyowa Hakko Kogyo Co Ltd | 持続性ドパミン経黒剤 |
| AU576907B2 (en) * | 1984-11-01 | 1988-09-08 | American Home Products Corporation | Oral vaccines comprising live recombinant adenoviruses |
| GB8518301D0 (en) * | 1985-07-19 | 1985-08-29 | Fujisawa Pharmaceutical Co | Hydrodynamically explosive systems |
| US5422121A (en) * | 1990-11-14 | 1995-06-06 | Rohm Gmbh | Oral dosage unit form |
| JP3134187B2 (ja) * | 1996-03-07 | 2001-02-13 | 武田薬品工業株式会社 | 放出制御組成物 |
| JPH10130171A (ja) * | 1996-09-04 | 1998-05-19 | Dot:Kk | 経口投与用医薬組成物 |
| JP3916716B2 (ja) * | 1996-12-26 | 2007-05-23 | フマキラー株式会社 | 防虫剤 |
-
2015
- 2015-10-30 JP JP2015214268A patent/JP6454630B2/ja not_active Expired - Lifetime
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