JP2015536933A - Ｗｎｔ経路結合剤を用いて神経内分泌腫瘍を処置する方法 - Google Patents

Ｗｎｔ経路結合剤を用いて神経内分泌腫瘍を処置する方法 Download PDF

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JP2015536933A
JP2015536933A JP2015539704A JP2015539704A JP2015536933A JP 2015536933 A JP2015536933 A JP 2015536933A JP 2015539704 A JP2015539704 A JP 2015539704A JP 2015539704 A JP2015539704 A JP 2015539704A JP 2015536933 A JP2015536933 A JP 2015536933A
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fzd
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ロバート ジョセフ スタッグ
ロバート ジョセフ スタッグ
ジェイコブ デュポン
ジェイコブ デュポン
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オンコメッド ファーマシューティカルズ インコーポレイテッド
オンコメッド ファーマシューティカルズ インコーポレイテッド
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • A—HUMAN NECESSITIES
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

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JP2015539704A 2012-10-23 2013-10-22 Ｗｎｔ経路結合剤を用いて神経内分泌腫瘍を処置する方法 Pending JP2015536933A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261717294P 2012-10-23 2012-10-23
US61/717,294 2012-10-23
US201361760529P 2013-02-04 2013-02-04
US61/760,529 2013-02-04
PCT/US2013/066087 WO2014066328A1 (en) 2012-10-23 2013-10-22 Methods of treating neuroendocrine tumors using wnt pathway-binding agents

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JP2015536933A true JP2015536933A (ja) 2015-12-24
JP2015536933A5 JP2015536933A5 (https=) 2016-12-15

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US (2) US9266959B2 (https=)
EP (1) EP2911691B1 (https=)
JP (1) JP2015536933A (https=)
CN (1) CN104768579A (https=)
AU (1) AU2013334790A1 (https=)
CA (1) CA2887711A1 (https=)
HK (1) HK1212216A1 (https=)
TW (1) TW201429489A (https=)
WO (1) WO2014066328A1 (https=)

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TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Ｗｎｔ拮抗劑及治療和篩選方法
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JP2016510411A (ja) 2013-02-04 2016-04-07 オンコメッド ファーマシューティカルズ インコーポレイテッド Ｗｎｔ経路インヒビターによる処置の方法およびモニタリング
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
JP2017526676A (ja) * 2014-08-27 2017-09-14 オンコメッド ファーマシューティカルズ インコーポレイテッド がんの処置のための併用療法
WO2016205566A1 (en) * 2015-06-16 2016-12-22 The Regents Of The University Of California Fzd7 specific antibodies and vaccines to treat cancer and control stem cell function
US10766962B2 (en) 2015-06-16 2020-09-08 The Regents Of The University Of California FZD7 specific antibodies and vaccines to treat cancer and control stem cell function
CN108601818A (zh) * 2016-01-28 2018-09-28 小利兰·斯坦福大学托管委员会 Wnt组合物及其无血清合成方法
US10919968B2 (en) * 2016-01-29 2021-02-16 Modmab Therapeutics Corporation Frizzled5 protein-binding agents
US10899839B2 (en) * 2016-03-28 2021-01-26 Tire Regents of the University of California Anti-Ryk antibodies and methods of using the same
JP2020529845A (ja) * 2017-08-01 2020-10-15 アンカサ リジェネレイティブ セラピューティクス，インク． Ｗｎｔ組成物および無血清培養条件からの処理の方法
MX2021010039A (es) * 2019-02-26 2021-09-21 Pieris Pharmaceuticals Gmbh Novedosas proteinas de fusion especificas para cd137 y gpc3.
US20220244263A1 (en) * 2019-05-28 2022-08-04 The Regents Of The University Of California Methods for treating small cell neuroendocrine and related cancers
CN110835372B (zh) * 2019-11-06 2020-12-01 上海健康医学院 一种靶向Frizzled7单克隆抗体及其制备方法与应用
KR20240149490A (ko) * 2023-04-05 2024-10-15 (주)케어젠 피부 상태 개선 활성을 갖는 펩타이드 및 이의 용도
KR20240149489A (ko) * 2023-04-05 2024-10-15 (주)케어젠 발모 촉진 또는 탈모 억제능을 갖는 펩타이드 및 이의 용도

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