JP2015535820A5 - - Google Patents
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- JP2015535820A5 JP2015535820A5 JP2015532387A JP2015532387A JP2015535820A5 JP 2015535820 A5 JP2015535820 A5 JP 2015535820A5 JP 2015532387 A JP2015532387 A JP 2015532387A JP 2015532387 A JP2015532387 A JP 2015532387A JP 2015535820 A5 JP2015535820 A5 JP 2015535820A5
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- hcdr3
- hcdr2
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261702834P | 2012-09-19 | 2012-09-19 | |
| US61/702,834 | 2012-09-19 | ||
| PCT/EP2013/069302 WO2014044686A1 (en) | 2012-09-19 | 2013-09-17 | Kir3dl2 binding agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015535820A JP2015535820A (ja) | 2015-12-17 |
| JP2015535820A5 true JP2015535820A5 (cg-RX-API-DMAC7.html) | 2016-10-27 |
| JP6507097B2 JP6507097B2 (ja) | 2019-04-24 |
Family
ID=49226157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015532387A Active JP6507097B2 (ja) | 2012-09-19 | 2013-09-17 | Ｋｉｒ３ｄｌ２結合剤 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US10577419B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2897980B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6507097B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104640880B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2013320360B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112015006060B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2881765C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2897980T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2770399T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL237220B (cg-RX-API-DMAC7.html) |
| MX (1) | MX369148B (cg-RX-API-DMAC7.html) |
| RU (1) | RU2682449C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014044686A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2539045T3 (es) * | 2009-01-19 | 2015-06-25 | Innate Pharma | Anticuerpos anti-KIR3D |
| EP2897980B1 (en) | 2012-09-19 | 2019-11-06 | Innate Pharma | Kir3dl2 binding agents |
| EP3521312B1 (en) * | 2013-02-20 | 2021-04-07 | Innate Pharma | A compound that specifically binds to kir3dl2 for use in the treatment of peripheral t cell lymphoma |
| WO2015136052A1 (en) | 2014-03-14 | 2015-09-17 | Innate Pharma | Humanized antibodies with increased stability |
| AU2015279321B2 (en) | 2014-06-27 | 2021-03-04 | Innate Pharma, S.A. | Multispecific antigen binding proteins |
| JP6822849B2 (ja) | 2014-06-27 | 2021-01-27 | イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． | 多重特異的ＮＫｐ４６結合タンパク質 |
| WO2016030488A1 (en) * | 2014-08-27 | 2016-03-03 | Innate Pharma | Treatment of celiac disease |
| US10487153B2 (en) | 2015-06-10 | 2019-11-26 | National Research Council Of Canada | Carbonic anhydrase IX-specific antibodies and uses thereof |
| AU2016284871B2 (en) | 2015-06-23 | 2022-09-29 | Innate Pharma | Multispecific NK engager proteins |
| EP3313876B1 (en) | 2015-06-23 | 2025-01-22 | Innate Pharma | Multispecific antigen binding proteins |
| WO2017156423A2 (en) * | 2016-03-11 | 2017-09-14 | Integrated Biotherapeutics, Inc. | Broadly protective antibody cocktails for treatment of filovirus hemorrhagic fever |
| US10858431B2 (en) * | 2016-06-30 | 2020-12-08 | Trellis Bioscience, Llc | Monoclonal antibodies targeting killer immunoglobulin-like receptor (KIR) family signaling |
| CN109863175A (zh) * | 2016-10-21 | 2019-06-07 | 依奈特制药公司 | 用抗-kir3dl2药剂进行的治疗 |
| US20190322767A1 (en) | 2016-12-23 | 2019-10-24 | Innate Pharma | Heterodimeric antigen binding proteins |
| EP3579879A4 (en) * | 2017-02-09 | 2020-12-16 | Memorial Sloan Kettering Cancer Center | ANTI-BODY ANTI-KIR3DL1 |
| CN111032083B (zh) * | 2017-05-24 | 2024-01-12 | 财团法人生物技术开发中心 | 抗globo h的人源化抗体及其在癌症治疗中的用途 |
| CA3067380A1 (en) * | 2017-06-15 | 2018-12-20 | Development Center For Biotechnology | Antibody-drug conjugates containing anti-globo h antibodies and uses thereof |
| TWI789399B (zh) * | 2017-06-22 | 2023-01-11 | 財團法人生物技術開發中心 | 不對稱異二聚fc-scfv融合抗globo h及抗cd3雙特異性抗體及其於癌症治療上之用途 |
| AU2018371114A1 (en) | 2017-11-21 | 2020-05-07 | Innate Pharma | Multispecific antigen binding proteins |
| US11560421B2 (en) * | 2018-02-09 | 2023-01-24 | Osaka University | Broad-spectrum monoclonal antibodies against chikungunya virus E1 structural protein |
| WO2020035345A1 (en) | 2018-08-14 | 2020-02-20 | Innate Pharma | Treatment of colorectal cancer by a combination of an anti-mica antibody and an anti-nkg2a antibody |
| WO2020152081A1 (en) | 2019-01-22 | 2020-07-30 | Innate Pharma | Treatment of t cell lymphoma |
| CN110950960B (zh) * | 2019-11-26 | 2021-05-14 | 中国农业大学 | 基于高通量测序和杂合杂交瘤技术的小分子化合物抗体的制备方法 |
| KR20220157446A (ko) * | 2020-03-23 | 2022-11-29 | 브리스톨-마이어스 스큅 컴퍼니 | 암을 치료하기 위한 항-ccr8 항체 |
| CA3209479A1 (en) | 2021-02-03 | 2022-08-11 | Mozart Therapeutics, Inc. | Binding agents and methods of using the same |
| MX2023011310A (es) | 2021-03-26 | 2023-10-05 | Innate Pharma | Anclajes de citocina para proteinas de celulas nk de union a nkp46. |
| WO2022214432A1 (en) | 2021-04-05 | 2022-10-13 | Innate Pharma | Immunohistochemistry methods and kir3dl2-specific reagents |
| WO2022258691A1 (en) | 2021-06-09 | 2022-12-15 | Innate Pharma | Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a |
| WO2022258678A1 (en) | 2021-06-09 | 2022-12-15 | Innate Pharma | Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a |
| MX2023014645A (es) | 2021-06-09 | 2024-01-31 | Innate Pharma | Proteinas acopladoras de celulas nk de union a nkp46 especificas de cd20. |
| BR112023025331A2 (pt) | 2021-06-09 | 2024-02-27 | Innate Pharma | Proteína multiespecífica, composição farmacêutica, célula recombinante, ácido nucleico ou conjunto de ácidos nucleicos, uso de uma proteína ou composição, métodos ou uso |
| CN113248609B (zh) * | 2021-07-14 | 2021-09-10 | 深圳市盛波尔生命科学技术有限责任公司 | 针对再生胰岛衍生蛋白1α的抗体组合以及包含其的检测试剂盒 |
| KR20240049858A (ko) * | 2021-07-30 | 2024-04-17 | 알.피.쉐러 테크놀러지즈 엘엘씨 | 항체-약물 접합체 및 이의 사용방법 |
| WO2023076876A1 (en) | 2021-10-26 | 2023-05-04 | Mozart Therapeutics, Inc. | Modulation of immune responses to viral vectors |
| CN120322463A (zh) | 2022-09-15 | 2025-07-15 | 艾维迪治疗知识产权有限公司 | 用于nk细胞的肿瘤靶向的多特异性抗原结合蛋白及其用途 |
| WO2024251884A1 (en) | 2023-06-09 | 2024-12-12 | Innate Pharma | Nk cell engager proteins comprising anti-cd20 and ant-nkp46 antibody, linked to il-2 in treatment of r/r b-nhl |
| CN117801108B (zh) * | 2023-12-06 | 2024-06-07 | 无锡傲锐东源生物科技有限公司 | 抗人mdm2蛋白单克隆抗体及其杂交瘤细胞株和应用 |
| WO2025191144A1 (en) | 2024-03-15 | 2025-09-18 | Avidicure Ip B.V. | Conjugates of egfr-specific antigen binding proteins and cytokines |
| WO2025191133A1 (en) | 2024-03-15 | 2025-09-18 | Avidicure Ip B.V. | Il-21 muteins, fusion proteins comprising the same and uses thereof |
| WO2025191136A1 (en) | 2024-03-15 | 2025-09-18 | Avidicure Ip B.V. | Muteins of 4-1bb ligand extracellular domain, fusion proteins comprising the same and uses thereof |
| WO2025245386A1 (en) * | 2024-05-23 | 2025-11-27 | La Jolla Institute For Immunology | Kir3dl2 as an anti-cancer target |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1922902A (en) | 2000-12-18 | 2002-07-01 | Inst Nat Sante Rech Med | Novel means for the diagnosis and therapy of CTCL |
| AU2004253770C1 (en) * | 2003-07-02 | 2010-04-15 | Innate Pharma | PAN-KIR2DL NK-receptor antibodies and their use in diagnostik and therapy |
| ES2539045T3 (es) | 2009-01-19 | 2015-06-25 | Innate Pharma | Anticuerpos anti-KIR3D |
| WO2011027310A1 (en) * | 2009-09-03 | 2011-03-10 | Koninklijke Philips Electronics N.V. | Novel tumor markers |
| US20130315933A1 (en) * | 2010-10-06 | 2013-11-28 | Christoph Renner | Antibodies Directed Against HLA-B27 Homodimers and Methods and Uses Thereof in Diagnosis and Therapy |
| EP2897980B1 (en) | 2012-09-19 | 2019-11-06 | Innate Pharma | Kir3dl2 binding agents |
| WO2014044681A1 (en) * | 2012-09-19 | 2014-03-27 | Innate Pharma | Kir3dl2 binding agents |
| EP3521312B1 (en) | 2013-02-20 | 2021-04-07 | Innate Pharma | A compound that specifically binds to kir3dl2 for use in the treatment of peripheral t cell lymphoma |
| US20160130346A1 (en) * | 2013-05-29 | 2016-05-12 | Institut National De La Sante Et De La Recherche Medicale | Kir3dl2 is a biomarker and a therapeutic target useful for respectively preventing and treating a subset of cutaneous and non-cutaneous peripheral t-cell lymphomas |
| WO2015136052A1 (en) | 2014-03-14 | 2015-09-17 | Innate Pharma | Humanized antibodies with increased stability |
| CN109863175A (zh) | 2016-10-21 | 2019-06-07 | 依奈特制药公司 | 用抗-kir3dl2药剂进行的治疗 |
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2013
- 2013-09-17 EP EP13765703.7A patent/EP2897980B1/en active Active
- 2013-09-17 CN CN201380048468.1A patent/CN104640880B/zh active Active
- 2013-09-17 ES ES13765703T patent/ES2770399T3/es active Active
- 2013-09-17 JP JP2015532387A patent/JP6507097B2/ja active Active
- 2013-09-17 BR BR112015006060-9A patent/BR112015006060B1/pt active IP Right Grant
- 2013-09-17 MX MX2015003476A patent/MX369148B/es active IP Right Grant
- 2013-09-17 CA CA2881765A patent/CA2881765C/en active Active
- 2013-09-17 AU AU2013320360A patent/AU2013320360B2/en active Active
- 2013-09-17 DK DK13765703.7T patent/DK2897980T3/da active
- 2013-09-17 WO PCT/EP2013/069302 patent/WO2014044686A1/en not_active Ceased
- 2013-09-17 RU RU2015104760A patent/RU2682449C2/ru active
-
2015
- 2015-02-12 IL IL237220A patent/IL237220B/en active IP Right Grant
- 2015-03-19 US US14/662,349 patent/US10577419B2/en active Active
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2020
- 2020-02-28 US US16/804,018 patent/US11858990B2/en active Active
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2023
- 2023-12-27 US US18/396,776 patent/US20240124579A1/en active Pending
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