JP2015533374A5 - - Google Patents

Download PDF

Info

Publication number
JP2015533374A5
JP2015533374A5 JP2015537841A JP2015537841A JP2015533374A5 JP 2015533374 A5 JP2015533374 A5 JP 2015533374A5 JP 2015537841 A JP2015537841 A JP 2015537841A JP 2015537841 A JP2015537841 A JP 2015537841A JP 2015533374 A5 JP2015533374 A5 JP 2015533374A5
Authority
JP
Japan
Prior art keywords
chain variable
variable domain
light chain
sequence
heavy chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015537841A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015533374A (ja
Filing date
Publication date
Priority claimed from US13/830,844 external-priority patent/US9309318B2/en
Application filed filed Critical
Publication of JP2015533374A publication Critical patent/JP2015533374A/ja
Publication of JP2015533374A5 publication Critical patent/JP2015533374A5/ja
Pending legal-status Critical Current

Links

JP2015537841A 2012-10-17 2013-10-17 抗il−21受容体抗体に関連する方法および組成物 Pending JP2015533374A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261715156P 2012-10-17 2012-10-17
US61/715,156 2012-10-17
US13/830,844 2013-03-14
US13/830,844 US9309318B2 (en) 2012-10-17 2013-03-14 Compositions relating to anti-IL-21 receptor antibodies
PCT/US2013/065514 WO2014062963A1 (en) 2012-10-17 2013-10-17 Methods and compositions relating to anti-il-21 receptor antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018014989A Division JP2018102302A (ja) 2012-10-17 2018-01-31 抗il−21受容体抗体に関連する方法および組成物

Publications (2)

Publication Number Publication Date
JP2015533374A JP2015533374A (ja) 2015-11-24
JP2015533374A5 true JP2015533374A5 (enExample) 2016-11-17

Family

ID=50475498

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015537841A Pending JP2015533374A (ja) 2012-10-17 2013-10-17 抗il−21受容体抗体に関連する方法および組成物
JP2018014989A Pending JP2018102302A (ja) 2012-10-17 2018-01-31 抗il−21受容体抗体に関連する方法および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018014989A Pending JP2018102302A (ja) 2012-10-17 2018-01-31 抗il−21受容体抗体に関連する方法および組成物

Country Status (8)

Country Link
US (2) US9309318B2 (enExample)
EP (2) EP2909237A1 (enExample)
JP (2) JP2015533374A (enExample)
AU (1) AU2013331139B2 (enExample)
CA (1) CA2888617A1 (enExample)
HK (1) HK1214279A1 (enExample)
MX (1) MX2015004892A (enExample)
WO (1) WO2014062963A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115052625B (zh) 2019-12-03 2024-11-01 埃沃特克国际有限责任公司 干扰素相关抗原结合蛋白及其用途
US12012441B2 (en) 2020-10-26 2024-06-18 Neptune Biosciences Llc Engineered human IL-21 cytokines and methods for using the same
WO2024040194A1 (en) 2022-08-17 2024-02-22 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4474893A (en) 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
DE3374837D1 (en) 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
US4737462A (en) 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4518584A (en) 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
DE3474511D1 (en) 1983-11-01 1988-11-17 Terumo Corp Pharmaceutical composition containing urokinase
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
ATE87659T1 (de) 1986-09-02 1993-04-15 Enzon Lab Inc Bindungsmolekuele mit einzelpolypeptidkette.
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5011912A (en) 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
US4965195A (en) 1987-10-26 1990-10-23 Immunex Corp. Interleukin-7
US4968607A (en) 1987-11-25 1990-11-06 Immunex Corporation Interleukin-1 receptors
US6010902A (en) 1988-04-04 2000-01-04 Bristol-Meyers Squibb Company Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
AU643427B2 (en) 1988-10-31 1993-11-18 Immunex Corporation Interleukin-4 receptors
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
AU651596B2 (en) 1990-06-05 1994-07-28 Immunex Corporation Type II interleukin-1 receptors
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
CA2089661C (en) 1990-08-29 2007-04-03 Nils Lonberg Transgenic non-human animals capable of producing heterologous antibodies
AU8727291A (en) 1990-10-29 1992-06-11 Cetus Oncology Corporation Bispecific antibodies, method of production, and uses thereof
US5582996A (en) 1990-12-04 1996-12-10 The Wistar Institute Of Anatomy & Biology Bifunctional antibodies and method of preparing same
DE4118120A1 (de) 1991-06-03 1992-12-10 Behringwerke Ag Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
DE122004000008I1 (de) 1991-06-14 2005-06-09 Genentech Inc Humanisierter Heregulin Antikörper.
US5262522A (en) 1991-11-22 1993-11-16 Immunex Corporation Receptor for oncostatin M and leukemia inhibitory factor
US5869619A (en) 1991-12-13 1999-02-09 Xoma Corporation Modified antibody variable domains
CA2146559A1 (en) 1992-10-23 1994-05-11 Melanie K. Spriggs Methods of preparing soluble, oligomeric proteins
US6558661B1 (en) 1992-12-29 2003-05-06 Genentech, Inc. Treatment of inflammatory bowel disease with IFN-γ inhibitors
US5457035A (en) 1993-07-23 1995-10-10 Immunex Corporation Cytokine which is a ligand for OX40
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US6706484B1 (en) * 1995-08-18 2004-03-16 Morphosys Ag Protein/(poly)peptide libraries
WO2000009560A2 (en) 1998-08-17 2000-02-24 Abgenix, Inc. Generation of modified molecules with increased serum half-lives
US20030191056A1 (en) 2002-04-04 2003-10-09 Kenneth Walker Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
WO2004083249A2 (en) * 2003-03-14 2004-09-30 Wyeth Antibodies against human il-21 receptor and uses therefor
JP5586952B2 (ja) * 2006-06-06 2014-09-10 クルセル ホランド ベー ヴェー 腸球菌に対する殺活性を有するヒトの結合分子及びその使用方法
PE20100141A1 (es) * 2008-05-23 2010-02-22 Wyeth Corp Proteina de union al receptor de interleuquina 21
BRPI0912998A2 (pt) 2008-05-23 2015-10-13 Wyeth Llc métodos de tratamento que utilizam proteínas de ligação do receptor para a interleucina-21
DK2356270T3 (da) * 2008-11-07 2016-12-12 Fabrus Llc Kombinatoriske antistofbiblioteker og anvendelser deraf
CN102532320A (zh) 2012-03-06 2012-07-04 中国药科大学 全人源的抗人白介素21受体的单链抗体及其应用
WO2013180295A1 (ja) 2012-06-01 2013-12-05 日本電信電話株式会社 パケット転送処理方法およびパケット転送処理装置
US9300829B2 (en) 2014-04-04 2016-03-29 Canon Kabushiki Kaisha Image reading apparatus and correction method thereof

Similar Documents

Publication Publication Date Title
JP7254699B2 (ja) 抗bcma重鎖のみ抗体
JP2024036342A (ja) Cd3を標的とする抗体、二重特異性抗体及びその使用
JP6893970B2 (ja) インターフェロンアルファ及びオメガ抗体アンタゴニスト
RU2011145428A (ru) АНТИТЕЛА ПРОТИВ TNF-α И ИХ ПРИМЕНЕНИЯ
US20200325236A1 (en) Agonistic 4-1bb monoclonal antibody
KR20160044063A (ko) 항-pd1 항체 및 이의 치료 및 진단 용도
JP2012526558A5 (enExample)
JP2018519364A5 (enExample)
US11525005B2 (en) Anti-CD40 antibody, antigen binding fragment thereof and medical use thereof
JP6604204B2 (ja) 新規抗ヒトbdca−2抗体
CN107921128B (zh) 抗cd154抗体及其使用方法
RU2017102514A (ru) Гуманизированные анти-тау-антитела
JP2016513467A5 (enExample)
JP2012524071A5 (enExample)
JP2007054079A (ja) ヒトmcp−1に対する抗体
Sadeghalvad et al. Introduction on monoclonal antibodies
CN103328508A (zh) 针对制癌蛋白m(osm)的抗原结合蛋白
RU2007143996A (ru) Антитела против il2
CN111886023A (zh) 针对tim-3的抗体及其用途
CN109641966A (zh) 抗il-22r抗体
WO2016021621A1 (ja) 新規抗ヒトIgβ抗体
JP2015533374A5 (enExample)
TW201904999A (zh) 抗gitr抗體、其抗原結合片段及其醫藥用途
JPWO2019156565A5 (enExample)
JP2025510266A (ja) Cd3を標的とする抗体及びその使用