JP2015528453A5 - - Google Patents
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- Publication number
- JP2015528453A5 JP2015528453A5 JP2015529001A JP2015529001A JP2015528453A5 JP 2015528453 A5 JP2015528453 A5 JP 2015528453A5 JP 2015529001 A JP2015529001 A JP 2015529001A JP 2015529001 A JP2015529001 A JP 2015529001A JP 2015528453 A5 JP2015528453 A5 JP 2015528453A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid residue
- alanine
- vaccine according
- valine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12182241.5 | 2012-08-29 | ||
| EP12182241.5A EP2703483A1 (en) | 2012-08-29 | 2012-08-29 | PCSK9 peptide vaccine |
| PCT/EP2013/067797 WO2014033158A2 (en) | 2012-08-29 | 2013-08-28 | Vaccine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017206158A Division JP2018048177A (ja) | 2012-08-29 | 2017-10-25 | Ｐｃｓｋ９ペプチドワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015528453A JP2015528453A (ja) | 2015-09-28 |
| JP2015528453A5 true JP2015528453A5 (enExample) | 2016-10-06 |
| JP6298820B2 JP6298820B2 (ja) | 2018-03-20 |
Family
ID=46785271
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015529001A Expired - Fee Related JP6298820B2 (ja) | 2012-08-29 | 2013-08-28 | Ｐｃｓｋ９ペプチドワクチン |
| JP2017206158A Pending JP2018048177A (ja) | 2012-08-29 | 2017-10-25 | Ｐｃｓｋ９ペプチドワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017206158A Pending JP2018048177A (ja) | 2012-08-29 | 2017-10-25 | Ｐｃｓｋ９ペプチドワクチン |
Country Status (21)
| Country | Link |
|---|---|
| US (5) | US9533030B2 (enExample) |
| EP (3) | EP2703483A1 (enExample) |
| JP (2) | JP6298820B2 (enExample) |
| KR (1) | KR102101201B1 (enExample) |
| CN (2) | CN104685053B (enExample) |
| AR (2) | AR092377A1 (enExample) |
| AU (2) | AU2013307319B2 (enExample) |
| CA (1) | CA2881318C (enExample) |
| CY (1) | CY1121067T1 (enExample) |
| DK (1) | DK2890785T3 (enExample) |
| ES (1) | ES2693572T3 (enExample) |
| HK (1) | HK1249859A1 (enExample) |
| HR (1) | HRP20181782T2 (enExample) |
| HU (1) | HUE040469T2 (enExample) |
| LT (1) | LT2890785T (enExample) |
| PL (1) | PL2890785T3 (enExample) |
| PT (1) | PT2890785T (enExample) |
| SI (1) | SI2890785T1 (enExample) |
| TR (1) | TR201815497T4 (enExample) |
| TW (1) | TWI615148B (enExample) |
| WO (1) | WO2014033158A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2703483A1 (en) * | 2012-08-29 | 2014-03-05 | Affiris AG | PCSK9 peptide vaccine |
| CA3003943A1 (en) | 2015-11-03 | 2017-05-11 | Affiris Ag | Method for vaccination against a self-antigen in a human patient |
| CN106822881A (zh) * | 2016-12-09 | 2017-06-13 | 四川大学 | 一种针对pcsk9的抗高血脂蛋白疫苗 |
| US11325945B2 (en) | 2017-04-12 | 2022-05-10 | Cadila Healthcare Limited | Peptide based PCSK9 vaccine |
| AU2021214166A1 (en) * | 2020-01-28 | 2022-09-22 | United Biomedical, Inc. | Peptide immunogens targeting PCSK9 and formulations thereof for prevention and treatment of PCSK9-mediated disorders |
| CN114672476A (zh) * | 2022-01-14 | 2022-06-28 | 复旦大学附属中山医院 | 人pcsk9蛋白的优势构象表位及其应用 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4866034A (en) | 1982-05-26 | 1989-09-12 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
| US4877611A (en) | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| EP0468520A3 (en) | 1990-07-27 | 1992-07-01 | Mitsui Toatsu Chemicals, Inc. | Immunostimulatory remedies containing palindromic dna sequences |
| DE69313134T2 (de) | 1992-06-25 | 1998-02-26 | Smithkline Beecham Biolog | Adjuvantien enthaltende impfstoffzusammensetzung |
| KR100310510B1 (ko) | 1993-03-23 | 2002-07-04 | 장 스테판느 | 3-0-탈아세틸화모노포스포릴지질a를함유하는백신조성물 |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| AU713040B2 (en) | 1994-07-15 | 1999-11-18 | University Of Iowa Research Foundation, The | Immunomodulatory oligonucleotides |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| WO1996040755A1 (en) | 1995-06-07 | 1996-12-19 | Dlo Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | An improved peptide, immunogenic composition and vaccine or medical preparation, a method to immunise animals against the hormone lhrh, and analogs of the lhrh tandem repeat peptide and their use as vaccine |
| US5856462A (en) | 1996-09-10 | 1999-01-05 | Hybridon Incorporated | Oligonucleotides having modified CpG dinucleosides |
| WO1998016247A1 (en) | 1996-10-11 | 1998-04-23 | The Regents Of The University Of California | Immunostimulatory polynucleotide/immunomodulatory molecule conjugates |
| AU743114B2 (en) | 1997-04-01 | 2002-01-17 | Corixa Corporation | Aqueous immunologic adjuvant compositions of monophosphoryl lipid A |
| GB9727262D0 (en) | 1997-12-24 | 1998-02-25 | Smithkline Beecham Biolog | Vaccine |
| AUPR593101A0 (en) | 2001-06-26 | 2001-07-19 | Council Of The Queensland Institute Of Medical Research, The | Cytomegalovirus t cell epitopes |
| ATE442378T1 (de) | 2002-09-20 | 2009-09-15 | Int Inst Cancer Immunology Inc | Substituierte wt1-peptide |
| GB0411411D0 (en) | 2004-05-21 | 2004-06-23 | Glaxosmithkline Biolog Sa | Vaccines |
| AR066042A1 (es) * | 2007-04-13 | 2009-07-22 | Novartis Ag | Moleculas y metodos para modular la proteina convertasa-subtilisina /quexina tipo 9 (pcsk9) |
| WO2009109428A2 (en) * | 2008-02-01 | 2009-09-11 | Alpha-O Peptides Ag | Self-assembling peptide nanoparticles useful as vaccines |
| KR101660578B1 (ko) | 2009-09-03 | 2016-09-27 | 화이자 백신스 엘엘씨 | Ｐｃｓｋ９ 백신 |
| EP2450382A1 (de) * | 2010-11-04 | 2012-05-09 | Affiris AG | Immunogenes Peptid |
| ES2565757T3 (es) * | 2011-09-13 | 2016-04-06 | Affiris Ag | Vacuna de PCSK9 |
| EP2703483A1 (en) * | 2012-08-29 | 2014-03-05 | Affiris AG | PCSK9 peptide vaccine |
-
2012
- 2012-08-29 EP EP12182241.5A patent/EP2703483A1/en not_active Withdrawn
-
2013
- 2013-08-26 TW TW102130502A patent/TWI615148B/zh not_active IP Right Cessation
- 2013-08-28 KR KR1020157008006A patent/KR102101201B1/ko not_active Expired - Fee Related
- 2013-08-28 CN CN201380040051.0A patent/CN104685053B/zh not_active Expired - Fee Related
- 2013-08-28 US US14/418,139 patent/US9533030B2/en active Active
- 2013-08-28 JP JP2015529001A patent/JP6298820B2/ja not_active Expired - Fee Related
- 2013-08-28 DK DK13756108.0T patent/DK2890785T3/en active
- 2013-08-28 TR TR2018/15497T patent/TR201815497T4/tr unknown
- 2013-08-28 CA CA2881318A patent/CA2881318C/en active Active
- 2013-08-28 EP EP13756108.0A patent/EP2890785B1/en active Active
- 2013-08-28 EP EP18179778.8A patent/EP3409770A3/en not_active Withdrawn
- 2013-08-28 CN CN201711057619.6A patent/CN107837392A/zh active Pending
- 2013-08-28 ES ES13756108.0T patent/ES2693572T3/es active Active
- 2013-08-28 HR HRP20181782TT patent/HRP20181782T2/hr unknown
- 2013-08-28 HU HUE13756108A patent/HUE040469T2/hu unknown
- 2013-08-28 AU AU2013307319A patent/AU2013307319B2/en not_active Ceased
- 2013-08-28 PL PL13756108T patent/PL2890785T3/pl unknown
- 2013-08-28 LT LTEP13756108.0T patent/LT2890785T/lt unknown
- 2013-08-28 PT PT13756108T patent/PT2890785T/pt unknown
- 2013-08-28 SI SI201331240T patent/SI2890785T1/sl unknown
- 2013-08-28 WO PCT/EP2013/067797 patent/WO2014033158A2/en not_active Ceased
- 2013-08-29 AR ARP130103067A patent/AR092377A1/es not_active Application Discontinuation
-
2016
- 2016-12-02 US US15/367,711 patent/US9999659B2/en not_active Expired - Fee Related
-
2017
- 2017-10-25 JP JP2017206158A patent/JP2018048177A/ja active Pending
-
2018
- 2018-05-21 US US15/984,800 patent/US10933123B2/en active Active
- 2018-07-19 HK HK18109348.0A patent/HK1249859A1/zh unknown
- 2018-11-05 CY CY181101153T patent/CY1121067T1/el unknown
- 2018-12-13 AU AU2018278933A patent/AU2018278933A1/en not_active Abandoned
-
2021
- 2021-01-11 US US17/145,571 patent/US11980657B2/en active Active
-
2023
- 2023-01-31 AR ARP230100224A patent/AR128395A2/es unknown
-
2024
- 2024-02-28 US US18/589,494 patent/US20240197844A1/en active Pending
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