JP2015524464A - 神経変性障害の治療で使用するための血漿中の成長因子を含む組成物 - Google Patents
神経変性障害の治療で使用するための血漿中の成長因子を含む組成物 Download PDFInfo
- Publication number
- JP2015524464A JP2015524464A JP2015525915A JP2015525915A JP2015524464A JP 2015524464 A JP2015524464 A JP 2015524464A JP 2015525915 A JP2015525915 A JP 2015525915A JP 2015525915 A JP2015525915 A JP 2015525915A JP 2015524464 A JP2015524464 A JP 2015524464A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- growth factor
- plasma
- treatment
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (6)
- 中枢神経系の神経変性疾患又はその他の疾患の治療において鼻腔内で投与できる治療用物質として使用するための、少なくとも1種の成長因子を含有する血中化合物から得られる組成物であって、成長因子を含有する血中化合物が、成長因子に富む血漿である、上記組成物。
- 上清である、請求項1に記載の組成物。
- ゲルである、請求項1に記載の組成物。
- 鼻腔内経路による中枢神経系の神経変性疾患又はその他の疾患の治療において使用するための治療物質の製造方法であって、製造方法が、少なくとも1種の成長因子を含有する血中化合物から得られる少なくとも1種の組成物の使用を含み、成長因子を含有する血中化合物が、成長因子に富む血漿である、上記方法。
- 組成物が、血漿上清である、請求項4に記載の方法。
- 組成物が血漿ゲルである、請求項4に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ESP201200810 | 2012-08-09 | ||
ES201200810A ES2442242B1 (es) | 2012-08-09 | 2012-08-09 | Composición con factores de crecimiento destinada al tratamiento intranasal de una enfermedad neurodegenerativa u otra patología del sistema nervioso central, y su método de fabricación. |
PCT/ES2013/000176 WO2014023860A1 (es) | 2012-08-09 | 2013-07-19 | Composición con factores de crecimiento obtenidos a partir del plasma sanguíneo destinada al tratamiento de enfermedades neurodegenerativas |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2015524464A true JP2015524464A (ja) | 2015-08-24 |
JP2015524464A5 JP2015524464A5 (ja) | 2016-07-21 |
JP6339568B2 JP6339568B2 (ja) | 2018-06-06 |
Family
ID=49111229
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015525915A Expired - Fee Related JP6339568B2 (ja) | 2012-08-09 | 2013-07-19 | 神経変性障害の治療で使用するための血漿中の成長因子を含む組成物 |
Country Status (17)
Country | Link |
---|---|
US (2) | US20140044795A1 (ja) |
EP (1) | EP2883569B1 (ja) |
JP (1) | JP6339568B2 (ja) |
KR (1) | KR102149162B1 (ja) |
CN (1) | CN104519961A (ja) |
AR (1) | AR092086A1 (ja) |
BR (1) | BR112015002760A2 (ja) |
CA (1) | CA2881075A1 (ja) |
CL (1) | CL2014003510A1 (ja) |
CO (1) | CO7170177A2 (ja) |
ES (2) | ES2442242B1 (ja) |
IN (1) | IN2014MN02675A (ja) |
MX (1) | MX357828B (ja) |
PE (1) | PE20150616A1 (ja) |
RU (1) | RU2696497C2 (ja) |
TW (1) | TWI649084B (ja) |
WO (1) | WO2014023860A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CL2016003282A1 (es) | 2016-12-21 | 2017-08-18 | Univ Chile | Virus aav/igf2, método de tratamiento genético y su uso en enfermedades relacionadas con mal plegamiento de proteínas tal como la enfermedad de huntington |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002531489A (ja) * | 1998-12-09 | 2002-09-24 | カイロン コーポレイション | 中枢神経系への神経栄養剤の投与 |
US6569204B1 (en) * | 1999-01-26 | 2003-05-27 | Eduardo Anitua Aldecoa | Bone tissue regenerating composition |
JP2009506076A (ja) * | 2005-08-26 | 2009-02-12 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ | 三叉神経疼痛のための薬物送達のための治療手順 |
JP2010535188A (ja) * | 2007-08-02 | 2010-11-18 | バイオテクノロジー インスティチュート、アイ エムエーエス ディー、 エス.エル. | 関節疾患若しくは関節痛の治療用又は審美的な目的若しくは他の目的のための皮膚の治療用の方法及び化合物並びに化合物の調製方法 |
WO2010130851A2 (es) * | 2009-05-14 | 2010-11-18 | Biotechnology Institute, I Mas D, S.L. | Método para la preparación de al menos un compuesto a partir de sangre, y dispositivo de extracción para ser utilizado en la ejecución de dicho método |
JP2011504163A (ja) * | 2007-06-08 | 2011-02-03 | ヘルスパートナーズ リサーチ ファウンデーション | 中枢神経系への治療化合物の標的化を高めるための薬学的組成物および方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7608258B2 (en) * | 2002-04-13 | 2009-10-27 | Allan Mishra | Method for treatment of tendinosis using platelet rich plasma |
US6811777B2 (en) * | 2002-04-13 | 2004-11-02 | Allan Mishra | Compositions and minimally invasive methods for treating incomplete connective tissue repair |
ES2221770B2 (es) | 2002-04-19 | 2006-07-16 | Eduardo Anitua Aldecoa | Metodo de preparacion de un compuesto para la regeneracion de tejidos. |
US20060004189A1 (en) * | 2004-07-02 | 2006-01-05 | James Gandy | Compositions for treating wounds and processes for their preparation |
NZ583851A (en) * | 2007-09-14 | 2012-06-29 | Formycon Gmbh | Use of slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases |
KR101114712B1 (ko) * | 2009-10-23 | 2012-02-29 | 세원셀론텍(주) | 염화칼슘용액과 제1형 콜라겐으로 혈소판풍부혈장(prp)을 활성화하여 조직재생을 유도하는 조성물의 제조방법 |
ES2369945B1 (es) | 2011-07-29 | 2012-10-15 | Eduardo Anitua Aldecoa | Procedimiento de obtención de una composición que contiene factores de crecimiento a partir de un compuesto sanguíneo, y composición obtenible por dicho procedimiento. |
-
2012
- 2012-08-09 ES ES201200810A patent/ES2442242B1/es not_active Expired - Fee Related
-
2013
- 2013-07-19 EP EP13756518.0A patent/EP2883569B1/en not_active Not-in-force
- 2013-07-19 ES ES13756518.0T patent/ES2662385T3/es active Active
- 2013-07-19 WO PCT/ES2013/000176 patent/WO2014023860A1/es active Application Filing
- 2013-07-19 CA CA2881075A patent/CA2881075A1/en not_active Abandoned
- 2013-07-19 TW TW102125858A patent/TWI649084B/zh not_active IP Right Cessation
- 2013-07-19 JP JP2015525915A patent/JP6339568B2/ja not_active Expired - Fee Related
- 2013-07-19 BR BR112015002760A patent/BR112015002760A2/pt not_active Application Discontinuation
- 2013-07-19 MX MX2015001677A patent/MX357828B/es active IP Right Grant
- 2013-07-19 PE PE2015000116A patent/PE20150616A1/es not_active Application Discontinuation
- 2013-07-19 KR KR1020157001551A patent/KR102149162B1/ko active IP Right Grant
- 2013-07-19 CN CN201380041280.4A patent/CN104519961A/zh active Pending
- 2013-07-19 RU RU2015104076A patent/RU2696497C2/ru active
- 2013-08-08 AR ARP130102835A patent/AR092086A1/es unknown
- 2013-08-08 US US13/962,340 patent/US20140044795A1/en not_active Abandoned
-
2014
- 2014-12-23 CL CL2014003510A patent/CL2014003510A1/es unknown
- 2014-12-31 IN IN2675MUN2014 patent/IN2014MN02675A/en unknown
-
2015
- 2015-01-20 CO CO15010369A patent/CO7170177A2/es unknown
-
2016
- 2016-03-08 US US15/063,969 patent/US20160184360A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002531489A (ja) * | 1998-12-09 | 2002-09-24 | カイロン コーポレイション | 中枢神経系への神経栄養剤の投与 |
US6569204B1 (en) * | 1999-01-26 | 2003-05-27 | Eduardo Anitua Aldecoa | Bone tissue regenerating composition |
JP2009506076A (ja) * | 2005-08-26 | 2009-02-12 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ | 三叉神経疼痛のための薬物送達のための治療手順 |
JP2011504163A (ja) * | 2007-06-08 | 2011-02-03 | ヘルスパートナーズ リサーチ ファウンデーション | 中枢神経系への治療化合物の標的化を高めるための薬学的組成物および方法 |
JP2010535188A (ja) * | 2007-08-02 | 2010-11-18 | バイオテクノロジー インスティチュート、アイ エムエーエス ディー、 エス.エル. | 関節疾患若しくは関節痛の治療用又は審美的な目的若しくは他の目的のための皮膚の治療用の方法及び化合物並びに化合物の調製方法 |
WO2010130851A2 (es) * | 2009-05-14 | 2010-11-18 | Biotechnology Institute, I Mas D, S.L. | Método para la preparación de al menos un compuesto a partir de sangre, y dispositivo de extracción para ser utilizado en la ejecución de dicho método |
Non-Patent Citations (3)
Title |
---|
CURRENT ALZHEIMER RESEARCH, vol. 4, JPN5015008717, 2007, pages 53 - 65, ISSN: 0003652092 * |
MEDICAL HYPOTHESES, vol. 73, no. 6, JPN6017007097, 2009, pages 1038 - 1040, ISSN: 0003652094 * |
NEUROPSYCHIATRIC DISEASE AND TREATMENT, vol. 4, no. 6, JPN6017007096, 2008, pages 1073 - 1087, ISSN: 0003652093 * |
Also Published As
Publication number | Publication date |
---|---|
AR092086A1 (es) | 2015-03-25 |
CO7170177A2 (es) | 2015-01-28 |
PE20150616A1 (es) | 2015-05-25 |
CA2881075A1 (en) | 2014-02-13 |
CL2014003510A1 (es) | 2015-05-04 |
US20160184360A1 (en) | 2016-06-30 |
IN2014MN02675A (ja) | 2015-08-28 |
WO2014023860A1 (es) | 2014-02-13 |
JP6339568B2 (ja) | 2018-06-06 |
ES2442242B1 (es) | 2014-11-25 |
RU2015104076A (ru) | 2016-09-27 |
RU2696497C2 (ru) | 2019-08-02 |
ES2662385T3 (es) | 2018-04-06 |
KR20150040860A (ko) | 2015-04-15 |
TW201408310A (zh) | 2014-03-01 |
CN104519961A (zh) | 2015-04-15 |
EP2883569A1 (en) | 2015-06-17 |
EP2883569B1 (en) | 2017-12-20 |
KR102149162B1 (ko) | 2020-08-31 |
TWI649084B (zh) | 2019-02-01 |
MX2015001677A (es) | 2015-04-10 |
ES2442242A1 (es) | 2014-02-10 |
MX357828B (es) | 2018-07-25 |
BR112015002760A2 (pt) | 2020-04-22 |
US20140044795A1 (en) | 2014-02-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Kaplani et al. | Wound healing related agents: Ongoing research and perspectives | |
Koerbel et al. | Evolution of vestibular schwannoma surgery: the long journey to current success | |
CN108503690B (zh) | 一种促进创伤后组织修复与再生的修复肽及其应用 | |
KR20200143407A (ko) | Cgrp를 억제하는데 사용하기 위한 신경독소 | |
KR20190093626A (ko) | 황반변성의 신규 치료 방법 | |
Lekic et al. | Evaluation of the hematoma consequences, neurobehavioral profiles, and histopathology in a rat model of pontine hemorrhage | |
Ursavas et al. | Olfactory ensheathing cells: Unique glial cells promising for treatments of spinal cord injury | |
Yao et al. | Tetrahedral framework nucleic acids facilitate neurorestoration of facial nerves by activating the NGF/PI3K/AKT pathway | |
Zhu et al. | Platelet-rich plasma combined with low-dose ultrashort wave therapy accelerates peripheral nerve regeneration | |
CN101014359A (zh) | 通过将神经胶质细胞系来源的神经营养因子直接注入到未定带内治疗人帕金森病的方法 | |
Sheykhhasan et al. | Plasma-rich in growth factor and its clinical application | |
Lee et al. | Functional recovery after injury of motor cortex in rats: effects of rehabilitation and stem cell transplantation in a traumatic brain injury model of cortical resection | |
JP6339568B2 (ja) | 神経変性障害の治療で使用するための血漿中の成長因子を含む組成物 | |
KR20220054372A (ko) | 신경학적 및 정신의학적 장애의 치료에 사용하기 위한 신경독소 조성물 | |
JP5883027B2 (ja) | 神経学的疾患治療法、ならびにそのための組成物および物質 | |
TWI327473B (en) | Composition for treating a cerebrovascular disease and a method for increasing expression of erythropoietin | |
CN114617865B (zh) | 乙酰左旋肉碱在制备用于预防或治疗静脉流出障碍性疾病的药物中的应用 | |
PYRAMIDAL | Susana Valero Freitag | |
WO2023072069A1 (zh) | 异野漆树苷及其衍生物用于促进神经修复的用途 | |
Züchner | Experimental models for spinal cord injury: From basic to translational studies | |
Han et al. | Improved Regenerative Responses of Injured Spinal Cord Nerve Fibers by the Treatment of Sukjihwang (Rehmanniae radix preparat) | |
Hesse | Surgical Treatments for Dementia | |
Liu et al. | Tannic acid as building block constructing injectable hydrogel and regulating microglial phenotype to enhance neuroplasticity for post-stroke rehabilitation | |
Pawar | Trans-nasal mucosal delivery of Bdnf antagonat oligonucleotides using heterotopic mucosal engrafting for Parkinson's disease | |
Narkilahti et al. | MODELING HYPOXIA-INDUCED INJURY AND ITS POTENTIAL TREATMENT IN VITRO NEURONAL NETWORKS |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20150206 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160531 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20160531 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20170302 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20170602 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20170802 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170828 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20171003 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20171228 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20180302 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180403 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20180427 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20180510 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6339568 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |