JP2015522582A5 - - Google Patents
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- Publication number
- JP2015522582A5 JP2015522582A5 JP2015519247A JP2015519247A JP2015522582A5 JP 2015522582 A5 JP2015522582 A5 JP 2015522582A5 JP 2015519247 A JP2015519247 A JP 2015519247A JP 2015519247 A JP2015519247 A JP 2015519247A JP 2015522582 A5 JP2015522582 A5 JP 2015522582A5
- Authority
- JP
- Japan
- Prior art keywords
- kdel
- amino acid
- endoplasmic reticulum
- retention signal
- reticulum retention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12382272.8 | 2012-07-06 | ||
| EP12382272 | 2012-07-06 | ||
| PCT/EP2013/064400 WO2014006225A1 (en) | 2012-07-06 | 2013-07-08 | Fluorescent fusion polypeptide, biosensor comprising said polypeptide and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015522582A JP2015522582A (ja) | 2015-08-06 |
| JP2015522582A5 true JP2015522582A5 (enExample) | 2016-08-04 |
| JP6393260B2 JP6393260B2 (ja) | 2018-09-19 |
Family
ID=48803514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015519247A Active JP6393260B2 (ja) | 2012-07-06 | 2013-07-08 | 蛍光融合ポリペプチド、該ポリペプチドを含むバイオセンサー及びそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9784728B2 (enExample) |
| EP (1) | EP2870475B1 (enExample) |
| JP (1) | JP6393260B2 (enExample) |
| CN (1) | CN104781667B (enExample) |
| CA (1) | CA2878126C (enExample) |
| DK (1) | DK2870475T3 (enExample) |
| ES (1) | ES2645431T3 (enExample) |
| IN (1) | IN2014MN02585A (enExample) |
| WO (1) | WO2014006225A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2870475T3 (en) | 2012-07-06 | 2017-09-18 | Innovative Tech In Biological Systems S L | FLUORESCING FUSION POLYPEPTIDE, BIOSENSOR INCLUDING POLYPEPTIDE AND APPLICATIONS THEREOF |
| US9784726B2 (en) | 2013-01-08 | 2017-10-10 | Atrogi Ab | Screening method, a kit, a method of treatment and a compound for use in a method of treatment |
| WO2018141987A1 (en) * | 2017-02-06 | 2018-08-09 | Innovative Technologies In Biological Systems Sl | Fluorescent fusion polypeptide capable of detecting phosphorylation of cellular membrane receptors by grks (g-protein receptor kinases) and/or receptor tyrosine kinases (rtks) |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH089640B2 (ja) * | 1994-05-19 | 1996-01-31 | 佑 本庶 | ヒト・インターロイキン−２受容体 |
| US6197928B1 (en) * | 1997-03-14 | 2001-03-06 | The Regents Of The University Of California | Fluorescent protein sensors for detection of analytes |
| US7192932B1 (en) * | 1997-04-29 | 2007-03-20 | Lauras As | Use of immunomodulating agents |
| CN1310758A (zh) * | 1998-05-20 | 2001-08-29 | 中外制药株式会社 | 基因克隆的新方法 |
| CA2349720A1 (en) * | 1998-11-12 | 2000-05-18 | Beth Israel Deaconess Medical Center | Stimulation of angiogenesis via syndecan-4 cytoplasmic domain signaling pathway |
| US7060793B2 (en) * | 1999-05-21 | 2006-06-13 | The Regents Of The University Of California | Circularly permuted fluorescent protein indicators |
| US20070037165A1 (en) * | 2000-09-08 | 2007-02-15 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| US7125660B2 (en) * | 2000-09-13 | 2006-10-24 | Archemix Corp. | Nucleic acid sensor molecules and methods of using same |
| JP2005507650A (ja) * | 2001-08-01 | 2005-03-24 | セロミックス インコーポレイテッド | 新規融合タンパク質及び分子結合に関するアッセイ |
| AU2003270149A1 (en) * | 2002-09-06 | 2004-03-29 | Forschungsverbund Berlin E. V. | Akap18 delta, a novel splicing variant of a protein kinase a anchor protein and the use of the same |
| JP4214206B2 (ja) * | 2002-12-10 | 2009-01-28 | 独立行政法人理化学研究所 | Ｆｒｅｔを利用した蛍光指示薬 |
| US7488583B2 (en) * | 2003-09-25 | 2009-02-10 | Odyssey Thera, Inc. | Fragment complementation assays for G-protein-coupled receptors and their signaling pathways |
| GB0411586D0 (en) * | 2004-05-24 | 2004-06-23 | Univ The Glasgow | Fluorescent protein |
| JP2008507995A (ja) * | 2004-08-02 | 2008-03-21 | セルーメン、インコーポレイテッド | 細胞内での分子相互作用の検出方法 |
| EP1997885A1 (en) * | 2007-05-29 | 2008-12-03 | AXXAM S.p.A. | Fluorescent proteins and methods of use thereof |
| EP2193141A1 (en) * | 2007-08-24 | 2010-06-09 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. | Genetically encoded calcium sensors comprising the c-terminal lobe of troponin c and a fluorescence tag |
| JP2009153399A (ja) * | 2007-12-25 | 2009-07-16 | National Institute Of Advanced Industrial & Technology | 一分子型リアルタイム生物発光イメージングプローブ |
| JP5798489B2 (ja) * | 2009-01-12 | 2015-10-21 | ストロ バイオファーマ， インコーポレイテッド | インビトロタンパク質合成システムを用いて非天然アミノ酸をタンパク質に選択的に導入するためのモノチャージシステム |
| EP2473186A4 (en) * | 2009-08-31 | 2013-07-10 | Ibc Pharmaceuticals Inc | BIS SPECIFIC IMMUNOZYTOKIN DOCK-AND-LOCK COMPLEXES AND THERAPEUTIC USE THEREOF |
| DK2870475T3 (en) | 2012-07-06 | 2017-09-18 | Innovative Tech In Biological Systems S L | FLUORESCING FUSION POLYPEPTIDE, BIOSENSOR INCLUDING POLYPEPTIDE AND APPLICATIONS THEREOF |
-
2013
- 2013-07-08 DK DK13739169.4T patent/DK2870475T3/en active
- 2013-07-08 EP EP13739169.4A patent/EP2870475B1/en active Active
- 2013-07-08 US US14/412,513 patent/US9784728B2/en active Active
- 2013-07-08 WO PCT/EP2013/064400 patent/WO2014006225A1/en not_active Ceased
- 2013-07-08 IN IN2585MUN2014 patent/IN2014MN02585A/en unknown
- 2013-07-08 CN CN201380045944.4A patent/CN104781667B/zh active Active
- 2013-07-08 JP JP2015519247A patent/JP6393260B2/ja active Active
- 2013-07-08 CA CA2878126A patent/CA2878126C/en active Active
- 2013-07-08 ES ES13739169.4T patent/ES2645431T3/es active Active
-
2017
- 2017-09-19 US US15/709,000 patent/US10883981B2/en active Active
- 2017-09-19 US US15/708,971 patent/US10877025B2/en active Active
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