JP2015522582A5 - - Google Patents
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- Publication number
- JP2015522582A5 JP2015522582A5 JP2015519247A JP2015519247A JP2015522582A5 JP 2015522582 A5 JP2015522582 A5 JP 2015522582A5 JP 2015519247 A JP2015519247 A JP 2015519247A JP 2015519247 A JP2015519247 A JP 2015519247A JP 2015522582 A5 JP2015522582 A5 JP 2015522582A5
- Authority
- JP
- Japan
- Prior art keywords
- kdel
- amino acid
- endoplasmic reticulum
- retention signal
- reticulum retention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12382272 | 2012-07-06 | ||
| EP12382272.8 | 2012-07-06 | ||
| PCT/EP2013/064400 WO2014006225A1 (en) | 2012-07-06 | 2013-07-08 | Fluorescent fusion polypeptide, biosensor comprising said polypeptide and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015522582A JP2015522582A (ja) | 2015-08-06 |
| JP2015522582A5 true JP2015522582A5 (enExample) | 2016-08-04 |
| JP6393260B2 JP6393260B2 (ja) | 2018-09-19 |
Family
ID=48803514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015519247A Active JP6393260B2 (ja) | 2012-07-06 | 2013-07-08 | 蛍光融合ポリペプチド、該ポリペプチドを含むバイオセンサー及びそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9784728B2 (enExample) |
| EP (1) | EP2870475B1 (enExample) |
| JP (1) | JP6393260B2 (enExample) |
| CN (1) | CN104781667B (enExample) |
| CA (1) | CA2878126C (enExample) |
| DK (1) | DK2870475T3 (enExample) |
| ES (1) | ES2645431T3 (enExample) |
| IN (1) | IN2014MN02585A (enExample) |
| WO (1) | WO2014006225A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6393260B2 (ja) | 2012-07-06 | 2018-09-19 | イノベーティブ テクノロジーズ イン バイオロジカル システムズ エセ．エレ． | 蛍光融合ポリペプチド、該ポリペプチドを含むバイオセンサー及びそれらの使用 |
| WO2014108449A1 (en) | 2013-01-08 | 2014-07-17 | Atrogi Ab | A screening method, a kit, a method of treatment and a compound for use in a method of treatment |
| ES2952996T3 (es) * | 2017-02-06 | 2023-11-07 | Innovative Tech In Biological Systems Sl | Polipéptido de fusión fluorescente capaz de detectar la fosforilación de receptores de membrana celular por GRK (cinasas receptoras de proteína G) y/o tirosina cinasas receptoras (RTK) |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH089640B2 (ja) * | 1994-05-19 | 1996-01-31 | 佑 本庶 | ヒト・インターロイキン−２受容体 |
| US6197928B1 (en) | 1997-03-14 | 2001-03-06 | The Regents Of The University Of California | Fluorescent protein sensors for detection of analytes |
| US7192932B1 (en) * | 1997-04-29 | 2007-03-20 | Lauras As | Use of immunomodulating agents |
| JP3471006B2 (ja) * | 1998-05-20 | 2003-11-25 | 中外製薬株式会社 | 新規な遺伝子クローニング方法 |
| CA2349720A1 (en) * | 1998-11-12 | 2000-05-18 | Beth Israel Deaconess Medical Center | Stimulation of angiogenesis via syndecan-4 cytoplasmic domain signaling pathway |
| US7060793B2 (en) * | 1999-05-21 | 2006-06-13 | The Regents Of The University Of California | Circularly permuted fluorescent protein indicators |
| US20070037165A1 (en) * | 2000-09-08 | 2007-02-15 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| US7125660B2 (en) * | 2000-09-13 | 2006-10-24 | Archemix Corp. | Nucleic acid sensor molecules and methods of using same |
| CA2453528C (en) * | 2001-08-01 | 2011-07-26 | Cellomics, Inc. | Novel fusion proteins and assays for molecular binding |
| WO2004022591A1 (de) * | 2002-09-06 | 2004-03-18 | Forschungsverbund Berlin E. V. | Akap18 delta, eine neue spleissvariante eines proteinkinase a-ankerproteins und verwendung dieser |
| JP4214206B2 (ja) * | 2002-12-10 | 2009-01-28 | 独立行政法人理化学研究所 | Ｆｒｅｔを利用した蛍光指示薬 |
| US7488583B2 (en) * | 2003-09-25 | 2009-02-10 | Odyssey Thera, Inc. | Fragment complementation assays for G-protein-coupled receptors and their signaling pathways |
| GB0411586D0 (en) * | 2004-05-24 | 2004-06-23 | Univ The Glasgow | Fluorescent protein |
| EP1774330A4 (en) * | 2004-08-02 | 2008-10-15 | Cellumen Inc | METHODS FOR DETECTION OF MOLECULAR INTERACTIONS IN CELLS |
| EP1997885A1 (en) * | 2007-05-29 | 2008-12-03 | AXXAM S.p.A. | Fluorescent proteins and methods of use thereof |
| US20110154515A1 (en) * | 2007-08-24 | 2011-06-23 | Oliver Griesbeck | Genetically encoded calcium sensors comprising the c-terminal lobe of troponin c and a fluorescence tag |
| JP2009153399A (ja) * | 2007-12-25 | 2009-07-16 | National Institute Of Advanced Industrial & Technology | 一分子型リアルタイム生物発光イメージングプローブ |
| EP2376647B1 (en) * | 2009-01-12 | 2014-03-05 | Sutro Biopharma, Inc. | Mono charging system for selectively introducing non-native amino acids into proteins using an in vitro protein synthesis system |
| CN102481348A (zh) * | 2009-08-31 | 2012-05-30 | Ibc药品公司 | 双特异性免疫细胞因子停靠-和-加锁(dnl)复合物及其治疗性用途 |
| JP6393260B2 (ja) | 2012-07-06 | 2018-09-19 | イノベーティブ テクノロジーズ イン バイオロジカル システムズ エセ．エレ． | 蛍光融合ポリペプチド、該ポリペプチドを含むバイオセンサー及びそれらの使用 |
-
2013
- 2013-07-08 JP JP2015519247A patent/JP6393260B2/ja active Active
- 2013-07-08 WO PCT/EP2013/064400 patent/WO2014006225A1/en not_active Ceased
- 2013-07-08 EP EP13739169.4A patent/EP2870475B1/en active Active
- 2013-07-08 CN CN201380045944.4A patent/CN104781667B/zh active Active
- 2013-07-08 US US14/412,513 patent/US9784728B2/en active Active
- 2013-07-08 IN IN2585MUN2014 patent/IN2014MN02585A/en unknown
- 2013-07-08 DK DK13739169.4T patent/DK2870475T3/en active
- 2013-07-08 ES ES13739169.4T patent/ES2645431T3/es active Active
- 2013-07-08 CA CA2878126A patent/CA2878126C/en active Active
-
2017
- 2017-09-19 US US15/708,971 patent/US10877025B2/en active Active
- 2017-09-19 US US15/709,000 patent/US10883981B2/en active Active
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