IN2014MN02585A - - Google Patents
Info
- Publication number
- IN2014MN02585A IN2014MN02585A IN2585MUN2014A IN2014MN02585A IN 2014MN02585 A IN2014MN02585 A IN 2014MN02585A IN 2585MUN2014 A IN2585MUN2014 A IN 2585MUN2014A IN 2014MN02585 A IN2014MN02585 A IN 2014MN02585A
- Authority
- IN
- India
- Prior art keywords
- peptide
- fluorescent
- linker
- fusion polypeptide
- protein binding
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 8
- 230000004927 fusion Effects 0.000 abstract 3
- 230000004807 localization Effects 0.000 abstract 3
- 230000014759 maintenance of location Effects 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 230000026683 transduction Effects 0.000 abstract 3
- 238000010361 transduction Methods 0.000 abstract 3
- 239000012528 membrane Substances 0.000 abstract 2
- LQRJAEQXMSMEDP-XCHBZYMASA-N peptide a Chemical compound N([C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](C)C(=O)NCCCC[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)C(\NC(=O)[C@@H](CCCCN)NC(=O)CNC(C)=O)=C/C=1C=CC=CC=1)C(N)=O)C(=O)C(\NC(=O)[C@@H](CCCCN)NC(=O)CNC(C)=O)=C\C1=CC=CC=C1 LQRJAEQXMSMEDP-XCHBZYMASA-N 0.000 abstract 2
- 210000003660 reticulum Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 210000000805 cytoplasm Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5035—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12382272 | 2012-07-06 | ||
| PCT/EP2013/064400 WO2014006225A1 (en) | 2012-07-06 | 2013-07-08 | Fluorescent fusion polypeptide, biosensor comprising said polypeptide and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN02585A true IN2014MN02585A (enExample) | 2015-07-24 |
Family
ID=48803514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2585MUN2014 IN2014MN02585A (enExample) | 2012-07-06 | 2013-07-08 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9784728B2 (enExample) |
| EP (1) | EP2870475B1 (enExample) |
| JP (1) | JP6393260B2 (enExample) |
| CN (1) | CN104781667B (enExample) |
| CA (1) | CA2878126C (enExample) |
| DK (1) | DK2870475T3 (enExample) |
| ES (1) | ES2645431T3 (enExample) |
| IN (1) | IN2014MN02585A (enExample) |
| WO (1) | WO2014006225A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6393260B2 (ja) | 2012-07-06 | 2018-09-19 | イノベーティブ テクノロジーズ イン バイオロジカル システムズ エセ．エレ． | 蛍光融合ポリペプチド、該ポリペプチドを含むバイオセンサー及びそれらの使用 |
| WO2014108449A1 (en) | 2013-01-08 | 2014-07-17 | Atrogi Ab | A screening method, a kit, a method of treatment and a compound for use in a method of treatment |
| ES2952996T3 (es) * | 2017-02-06 | 2023-11-07 | Innovative Tech In Biological Systems Sl | Polipéptido de fusión fluorescente capaz de detectar la fosforilación de receptores de membrana celular por GRK (cinasas receptoras de proteína G) y/o tirosina cinasas receptoras (RTK) |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH089640B2 (ja) * | 1994-05-19 | 1996-01-31 | 佑 本庶 | ヒト・インターロイキン−２受容体 |
| US6197928B1 (en) | 1997-03-14 | 2001-03-06 | The Regents Of The University Of California | Fluorescent protein sensors for detection of analytes |
| US7192932B1 (en) * | 1997-04-29 | 2007-03-20 | Lauras As | Use of immunomodulating agents |
| JP3471006B2 (ja) * | 1998-05-20 | 2003-11-25 | 中外製薬株式会社 | 新規な遺伝子クローニング方法 |
| CA2349720A1 (en) * | 1998-11-12 | 2000-05-18 | Beth Israel Deaconess Medical Center | Stimulation of angiogenesis via syndecan-4 cytoplasmic domain signaling pathway |
| US7060793B2 (en) * | 1999-05-21 | 2006-06-13 | The Regents Of The University Of California | Circularly permuted fluorescent protein indicators |
| US20070037165A1 (en) * | 2000-09-08 | 2007-02-15 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| US7125660B2 (en) * | 2000-09-13 | 2006-10-24 | Archemix Corp. | Nucleic acid sensor molecules and methods of using same |
| CA2453528C (en) * | 2001-08-01 | 2011-07-26 | Cellomics, Inc. | Novel fusion proteins and assays for molecular binding |
| WO2004022591A1 (de) * | 2002-09-06 | 2004-03-18 | Forschungsverbund Berlin E. V. | Akap18 delta, eine neue spleissvariante eines proteinkinase a-ankerproteins und verwendung dieser |
| JP4214206B2 (ja) * | 2002-12-10 | 2009-01-28 | 独立行政法人理化学研究所 | Ｆｒｅｔを利用した蛍光指示薬 |
| US7488583B2 (en) * | 2003-09-25 | 2009-02-10 | Odyssey Thera, Inc. | Fragment complementation assays for G-protein-coupled receptors and their signaling pathways |
| GB0411586D0 (en) * | 2004-05-24 | 2004-06-23 | Univ The Glasgow | Fluorescent protein |
| EP1774330A4 (en) * | 2004-08-02 | 2008-10-15 | Cellumen Inc | METHODS FOR DETECTION OF MOLECULAR INTERACTIONS IN CELLS |
| EP1997885A1 (en) * | 2007-05-29 | 2008-12-03 | AXXAM S.p.A. | Fluorescent proteins and methods of use thereof |
| US20110154515A1 (en) * | 2007-08-24 | 2011-06-23 | Oliver Griesbeck | Genetically encoded calcium sensors comprising the c-terminal lobe of troponin c and a fluorescence tag |
| JP2009153399A (ja) * | 2007-12-25 | 2009-07-16 | National Institute Of Advanced Industrial & Technology | 一分子型リアルタイム生物発光イメージングプローブ |
| EP2376647B1 (en) * | 2009-01-12 | 2014-03-05 | Sutro Biopharma, Inc. | Mono charging system for selectively introducing non-native amino acids into proteins using an in vitro protein synthesis system |
| CN102481348A (zh) * | 2009-08-31 | 2012-05-30 | Ibc药品公司 | 双特异性免疫细胞因子停靠-和-加锁(dnl)复合物及其治疗性用途 |
| JP6393260B2 (ja) | 2012-07-06 | 2018-09-19 | イノベーティブ テクノロジーズ イン バイオロジカル システムズ エセ．エレ． | 蛍光融合ポリペプチド、該ポリペプチドを含むバイオセンサー及びそれらの使用 |
-
2013
- 2013-07-08 JP JP2015519247A patent/JP6393260B2/ja active Active
- 2013-07-08 WO PCT/EP2013/064400 patent/WO2014006225A1/en not_active Ceased
- 2013-07-08 EP EP13739169.4A patent/EP2870475B1/en active Active
- 2013-07-08 CN CN201380045944.4A patent/CN104781667B/zh active Active
- 2013-07-08 US US14/412,513 patent/US9784728B2/en active Active
- 2013-07-08 IN IN2585MUN2014 patent/IN2014MN02585A/en unknown
- 2013-07-08 DK DK13739169.4T patent/DK2870475T3/en active
- 2013-07-08 ES ES13739169.4T patent/ES2645431T3/es active Active
- 2013-07-08 CA CA2878126A patent/CA2878126C/en active Active
-
2017
- 2017-09-19 US US15/708,971 patent/US10877025B2/en active Active
- 2017-09-19 US US15/709,000 patent/US10883981B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2870475B1 (en) | 2017-06-07 |
| ES2645431T3 (es) | 2017-12-05 |
| US9784728B2 (en) | 2017-10-10 |
| CA2878126A1 (en) | 2014-01-09 |
| US20180003697A1 (en) | 2018-01-04 |
| US10883981B2 (en) | 2021-01-05 |
| CA2878126C (en) | 2022-05-10 |
| US10877025B2 (en) | 2020-12-29 |
| US20150185205A1 (en) | 2015-07-02 |
| DK2870475T3 (en) | 2017-09-18 |
| JP2015522582A (ja) | 2015-08-06 |
| CN104781667B (zh) | 2017-06-13 |
| CN104781667A (zh) | 2015-07-15 |
| US20180003698A1 (en) | 2018-01-04 |
| JP6393260B2 (ja) | 2018-09-19 |
| EP2870475A1 (en) | 2015-05-13 |
| WO2014006225A1 (en) | 2014-01-09 |
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