JP2015522535A5 - - Google Patents

Download PDF

Info

Publication number
JP2015522535A5
JP2015522535A5 JP2015511694A JP2015511694A JP2015522535A5 JP 2015522535 A5 JP2015522535 A5 JP 2015522535A5 JP 2015511694 A JP2015511694 A JP 2015511694A JP 2015511694 A JP2015511694 A JP 2015511694A JP 2015522535 A5 JP2015522535 A5 JP 2015522535A5
Authority
JP
Japan
Prior art keywords
acid
docosa
hydroxy
eicosa
hexaenoic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015511694A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015522535A (ja
JP6370775B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/040314 external-priority patent/WO2013170006A2/en
Publication of JP2015522535A publication Critical patent/JP2015522535A/ja
Publication of JP2015522535A5 publication Critical patent/JP2015522535A5/ja
Application granted granted Critical
Publication of JP6370775B2 publication Critical patent/JP6370775B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015511694A 2012-05-10 2013-05-09 天然の特異的炎症収束性メディエータおよびその前駆物質を含有する、抗炎症活性を有する油 Active JP6370775B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261645281P 2012-05-10 2012-05-10
US61/645,281 2012-05-10
PCT/US2013/040314 WO2013170006A2 (en) 2012-05-10 2013-05-09 Oils with anti-inflammatory activity containing natural specialized proresolving mediators and their precursors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018131272A Division JP6821626B2 (ja) 2012-05-10 2018-07-11 天然の特異的炎症収束性メディエータおよびその前駆物質を含有する、抗炎症活性を有する油

Publications (3)

Publication Number Publication Date
JP2015522535A JP2015522535A (ja) 2015-08-06
JP2015522535A5 true JP2015522535A5 (enExample) 2016-06-30
JP6370775B2 JP6370775B2 (ja) 2018-08-08

Family

ID=49551457

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015511694A Active JP6370775B2 (ja) 2012-05-10 2013-05-09 天然の特異的炎症収束性メディエータおよびその前駆物質を含有する、抗炎症活性を有する油
JP2018131272A Active JP6821626B2 (ja) 2012-05-10 2018-07-11 天然の特異的炎症収束性メディエータおよびその前駆物質を含有する、抗炎症活性を有する油

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018131272A Active JP6821626B2 (ja) 2012-05-10 2018-07-11 天然の特異的炎症収束性メディエータおよびその前駆物質を含有する、抗炎症活性を有する油

Country Status (12)

Country Link
US (6) US10568858B2 (enExample)
EP (2) EP4205546A1 (enExample)
JP (2) JP6370775B2 (enExample)
CN (3) CN116173001A (enExample)
AU (1) AU2013259503B2 (enExample)
CA (1) CA2873055C (enExample)
DK (1) DK2858496T3 (enExample)
ES (1) ES2946109T3 (enExample)
NZ (1) NZ702325A (enExample)
PL (1) PL2858496T3 (enExample)
PT (1) PT2858496T (enExample)
WO (1) WO2013170006A2 (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
AU2013259503B2 (en) 2012-05-10 2017-03-16 Solutex Na Llc Oils with anti-inflammatory activity containing natural specialized proresolving mediators and their precursors
GB201301626D0 (en) * 2013-01-30 2013-03-13 Dignity Sciences Ltd Composition comprising 15-OHEPA and methods of using the same
US9902681B2 (en) 2013-05-30 2018-02-27 The Brigham And Women's Hospital, Inc. N-3 immunoresolvents: structures and actions
ES2727387T3 (es) 2013-11-15 2019-10-15 Ds Biopharma Ltd Sal de lisina de ácido 15-hidroxi-8(Z),11(Z),13(E)-eicosatrienoico
RU2685706C2 (ru) * 2014-01-10 2019-04-23 Эфиммьюн Лимитед Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением
JP6604529B2 (ja) * 2014-01-29 2019-11-13 岩手県 ヒドロキシエイコサペンタエン酸の取得方法
JP6315536B2 (ja) * 2014-01-29 2018-04-25 岩手県 Ppar活性化剤
TWI725937B (zh) 2014-06-06 2021-05-01 美商海洋原料公司 ω-3組成物、劑型及使用方法
MA41120A (fr) 2014-12-02 2017-10-10 Afimmune Ltd Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci
CN107405324A (zh) * 2015-01-16 2017-11-28 艾菲穆恩有限公司 包含15‑hepe的组合物和其使用方法
WO2016130522A1 (en) * 2015-02-09 2016-08-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compounds, compositions, and methods for the treatment of inflammatory, degenerative, and neurodegenerative diseases
US9682034B2 (en) 2015-03-10 2017-06-20 Elc Management Llc Methods and compositions for treating skin to resolve inflammation and screening for actives that stimulate pro-resolution pathways
CN112245420A (zh) * 2015-07-21 2021-01-22 艾菲穆恩有限公司 用于治疗或预防癌症和神经疾病的包括15-hepe的组合物
WO2017041094A1 (en) 2015-09-03 2017-03-09 Solutex Na Llc Compositions comprising omega-3 fatty acids, 17-hdha and 18- hepe and methods of using same
ES2607715B1 (es) * 2015-10-01 2018-01-17 Solutex Na, Lcc Proceso para la preparación y estabilización de emulsiones con omega-3 mediante redes cristalinas isométricas de derivados de celulosa
AU2016370626B2 (en) * 2015-12-18 2020-08-20 Afimmune Limited Compositions comprising 15-HEPE and methods of using the same
KR102437682B1 (ko) 2016-06-03 2022-08-29 테티스 파마수티컬스 엘엘씨 특화된 사전 해소 매개체의 염에 관한 조성물 및 방법
EP3570827B1 (en) * 2017-01-18 2025-06-25 Universitat Autònoma de Barcelona Maresin for use in treating multiple sclerosis and amyotrophic lateral sclerosis
WO2019016580A1 (en) 2017-07-20 2019-01-24 Universitat Autonoma De Barcelona MARESINS FOR USE IN THE TREATMENT OF CNS INJURIES
KR101981534B1 (ko) * 2017-09-01 2019-05-23 (주)솔빛피앤에프 프로텍틴 dx를 유효성분으로 함유하는 고지혈증 또는 지방간 질환 예방 또는 치료용 조성물
KR102003153B1 (ko) * 2018-01-17 2019-07-23 연세대학교 산학협력단 레졸빈 d2를 유효성분으로 함유하는 피부 염증 치료용 조성물
CN111989399B (zh) * 2018-04-16 2024-07-12 韩国生命工学研究院 多不饱和脂肪酸的多羟基衍生物的制备方法
CN108578398A (zh) * 2018-06-11 2018-09-28 温州医科大学 巨噬素在制备预防或治疗类风湿性关节炎的药物中的应用
NO345574B1 (en) * 2018-06-19 2021-04-26 Epax Norway As Composition for treatment of dry eye disease and meibomianitis
WO2019243887A1 (en) 2018-06-22 2019-12-26 Ambiotis Method for restoration of the natural capacity of the body to end inflammation by personalization of the food supplementation and objectification of its effect
CA3114750A1 (en) 2018-10-09 2020-04-16 University Of Rochester Treatment of vulvovaginal disorders
KR102673270B1 (ko) * 2018-10-15 2024-06-07 (주)아모레퍼시픽 피부장벽 강화용 조성물
US11400057B2 (en) 2018-10-19 2022-08-02 University Of Rochester Treatment of vulvar pain
KR102704402B1 (ko) 2018-10-24 2024-09-06 (주)아모레퍼시픽 피부장벽 강화용 조성물
WO2020109480A1 (en) * 2018-11-30 2020-06-04 Evonik Operations Gmbh Preparation for use to increase the formation of one or more specialized pro-resolving lipid mediators (spm)
US20220308071A1 (en) * 2019-06-13 2022-09-29 The Regents Of The University Of California Methods and compositions for determination of liver fibrosis
CN110420224A (zh) * 2019-07-25 2019-11-08 江苏华豚药业有限公司 河豚肝油皂化物的应用及其制备方法
CN118252869A (zh) * 2019-08-01 2024-06-28 赢创运营有限公司 包含ω-3脂肪酸盐和来自乳香属物种的胶树脂提取物的制剂
US11607623B2 (en) 2019-08-08 2023-03-21 Cornerstone Technologies Llc Dynamic interface system and its application in supercritical fluid extraction and chromatography
GB201913383D0 (en) * 2019-09-17 2019-10-30 Univ London Queen Mary Methods for predicting patient response to DMARDs
KR102870005B1 (ko) * 2019-09-25 2025-10-17 (주)아모레퍼시픽 피부장벽 강화용 조성물
EP4071241A4 (en) * 2019-12-06 2023-10-18 Korea Research Institute of Bioscience and Biotechnology MONO- OR DIHYDROXY DERIVATIVES OF POLY UNSATURATED FATTY ACIDS, METHOD FOR THEIR PRODUCTION AND THEIR USE
KR102256823B1 (ko) * 2019-12-06 2021-05-26 한국생명공학연구원 도코사헥사노엔산 유도체를 함유하는 주름 개선, 아토피피부염 개선 및 피부 장벽 강화용 복합 조성물
JP2023504205A (ja) * 2019-12-09 2023-02-01 ザ ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ 角膜病変の治療のための生体分子
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
US20230273228A1 (en) 2020-07-17 2023-08-31 Solutex Gc, S.L. Diagnostic Method and Compounds for the Treatment of Infections Caused by a Pathogen
WO2022049168A1 (en) * 2020-09-04 2022-03-10 Dsm Ip Assets B.V. 17(s)-hdpa for metabolic-syndrome related disorders
MX2023006157A (es) 2020-12-04 2023-06-08 Chemo Res S L Mediadores lipidicos proresolutivos especializados para el tratamiento del pcos.
US20240198254A1 (en) * 2021-04-27 2024-06-20 K.D. Pharma Bexbach Gmbh Method for separating a mixture
EP4329742A4 (en) * 2021-04-29 2025-02-26 Amarin Pharmaceuticals Ireland Limited COMPOSITIONS COMPRISING EPA AND METHODS OF USE THEREOF FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT
KR20220159751A (ko) 2021-05-26 2022-12-05 (주)아모레퍼시픽 미백용 조성물 및 이를 이용한 피부 미백방법
KR102662544B1 (ko) * 2021-10-19 2024-05-03 서울대학교산학협력단 참문어 추출물을 유효성분으로 포함하는 만성 폐쇄성 폐질환 예방 또는 치료용 약학적 조성물
WO2023180569A1 (en) 2022-03-25 2023-09-28 Chemo Research , S.L. Specialized pro-resolving lipid mediators for treating long covid-19
CN115466776B (zh) * 2022-09-26 2025-06-27 中国医学科学院基础医学研究所 检测嗜酸性粒细胞的试剂、嗜酸性粒细胞及其胞质内容物和羟基二十二碳六烯酸的应用
CN116139122B (zh) * 2023-02-28 2025-11-07 武汉大学人民医院(湖北省人民医院) 消退素d2在制备缓解和/或治疗心肌梗死及其相关疾病的药物中的应用
WO2025023183A1 (ja) * 2023-07-21 2025-01-30 国立大学法人大阪大学 炎症性腸疾患を抑制する脂肪酸代謝産物
CN117257787A (zh) * 2023-11-12 2023-12-22 重庆医科大学附属第二医院 巨噬素1在制备预防或治疗自身免疫性葡萄膜炎药物中的应用
WO2025233510A1 (en) 2024-05-10 2025-11-13 Chemo Research, S.L. Specialized pro-resolving lipid mediators for treating depression, anxiety, and/or stress
WO2026017754A1 (en) 2024-07-17 2026-01-22 Universitat Autònoma De Barcelona Maresin formulation
CN121994974B (zh) * 2026-04-09 2026-06-16 深圳保时健生物工程有限公司 微藻油中促炎症消退因子(SPMs)含量的检测方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
JPH01169354A (ja) 1987-12-25 1989-07-04 Hitachi Ltd 超臨界炭酸ガス抽出物の分取方法
US4966876A (en) 1989-08-22 1990-10-30 Viswanatha Sankaran Transesterification of triglycerides
US5133902A (en) 1989-08-22 1992-07-28 Viswanatha Sankaran Transesterification of triglycerides
IT1274734B (it) 1994-08-25 1997-07-24 Prospa Bv Composizioni farmaceutiche contenenti acidi grassi poliinsaturi, loro esteri o sali, unitamente a vitamine o provitamine antiossidanti
KR100234947B1 (ko) 1997-06-05 1999-12-15 이형도 멀티 탭 고주파 모듈레이터
US6284268B1 (en) 1997-12-10 2001-09-04 Cyclosporine Therapeutics Limited Pharmaceutical compositions containing an omega-3 fatty acid oil
JP4175698B2 (ja) * 1998-06-19 2008-11-05 サントリー株式会社 新規なトリグリセリド及びそれを含む組成物
IL151299A0 (en) * 2000-02-16 2003-04-10 Brigham & Womens Hospital Aspirin-triggered lipid mediators
ATE327744T1 (de) * 2001-03-20 2006-06-15 Sanol Arznei Schwarz Gmbh Neue verwendung von peptidverbindungen bei der behandlung von nicht-neuropathischem entzündungsschmerz
US20040176451A1 (en) 2001-06-18 2004-09-09 Tadakazu Tamai Pparg agonistic medicinal compositions
US7759395B2 (en) 2002-08-12 2010-07-20 The Brigham And Women's Hospital, Inc. Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma
JPWO2004048497A1 (ja) 2002-11-22 2006-03-30 日本水産株式会社 高度不飽和脂肪酸、その塩、またはそのエステルを含有する外用組成物
JP4280158B2 (ja) * 2002-12-27 2009-06-17 富士フイルム株式会社 ドコサヘキサエン酸生産能を有する微生物及びその利用
US20090318394A1 (en) * 2004-11-19 2009-12-24 Julie Nauroth Long Chain Polyunsaturated Fatty Acids and Methods of Making and Using the Same
CA2588166A1 (en) * 2004-11-19 2006-05-26 Martek Biosciences Corporation Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same
JP2009051732A (ja) * 2005-12-13 2009-03-12 Meiji Seika Kaisha Ltd Pparリガンド活性を有する組成物
EP2120920A4 (en) * 2007-02-20 2011-06-15 Martek Biosciences Corp OXYLIPINES OF LONG-CHAIN MULTIPLE-UNSATURATED FATTY ACIDS AND METHOD FOR THEIR PREPARATION AND USE
US20090023808A1 (en) * 2007-06-29 2009-01-22 Martek Biosciences Corporation Production and Purification of Esters of Polyunsaturated Fatty Acids
KR101650584B1 (ko) 2007-08-31 2016-08-23 디에스엠 아이피 어셋츠 비.브이. 다중불포화된 지방산 함유 고체 지방 조성물 및 그의 용도 및 생산
ES2569371T3 (es) * 2008-09-16 2016-05-10 The Brigham And Women's Hospital Inc. Compuestos del ácido 7,14-dihidroxidocosahexaenoico
EP2415748A4 (en) 2009-02-20 2013-08-07 Univ Tokyo NEW INFLAMMATORY COMPOUNDS
US20110071090A1 (en) 2009-03-11 2011-03-24 Stable Solutions Llc Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle
CL2009001343A1 (es) * 2009-06-02 2009-07-10 Golden Omega S A Proceso de obtencion concentrado de esteres de epa y dha a partir de aceite marino, que comprende agregar al aceite alcali y agua a menos de 100 grados celsius, agregar solvente, separar fase de refinado, agregar acido, separar la fase no acuosa y agregar alcohol y un catalizador a menos de 150 grados celsius, desolventilizar y destilar.
US8479921B2 (en) 2009-12-09 2013-07-09 Amcor Flexibles, Inc. Child resistant blister package
WO2011087981A2 (en) 2010-01-15 2011-07-21 E. I. Du Pont De Nemours And Company Clinical benefits of eicosapentaenoic acid in humans
EP2607358A4 (en) 2010-08-19 2014-01-29 Univ Tokyo NEW OMEGA-3 FATTY ACIDS RECOVERY-RESISTANT METABOLITE
US8865685B2 (en) 2011-06-30 2014-10-21 Johnson & Johnson Vision Care, Inc. Esters for treatment of ocular inflammatory conditions
PH12014501474B1 (en) 2011-12-27 2024-01-19 Nuseed Global Innovation Ltd Processes for producing lipids
AU2013259503B2 (en) 2012-05-10 2017-03-16 Solutex Na Llc Oils with anti-inflammatory activity containing natural specialized proresolving mediators and their precursors
MX363035B (es) 2013-06-27 2019-03-06 Smartfish As Uso de una composicion que comprende aceite de pescado y jugo para el tratamiento de inflamacion.
RU2685706C2 (ru) 2014-01-10 2019-04-23 Эфиммьюн Лимитед Фармацевтические композиции, содержащие 15-гэпк, и способы лечения астмы и заболеваний легких с их применением
WO2017041094A1 (en) 2015-09-03 2017-03-09 Solutex Na Llc Compositions comprising omega-3 fatty acids, 17-hdha and 18- hepe and methods of using same

Similar Documents

Publication Publication Date Title
WO2013170006A4 (en) Oils with anti-inflammatory activity containing natural specialized proresolving mediators and their precursors
JP6602821B2 (ja) 加熱クロマトグラフィー分離方法
JP6248143B2 (ja) 魚油から高純度のepaを生成するためのsmb方法
JP6423436B2 (ja) ポリ不飽和脂肪酸を製造するためのクロマトグラフィ方法
US10723973B2 (en) Multi-step separation process
JP6664328B2 (ja) エイコサペンタエン酸アルキルエステルを含有する組成物及びその製造方法
JP2008528743A (ja) Dhaを含有する脂肪酸組成物を製造する方法
JP7394748B2 (ja) 微生物油及び微生物油の製造方法
JPWO2017038860A1 (ja) 遊離多価不飽和脂肪酸含有組成物及びその製造方法
JP2012513380A5 (enExample)
CN111635308A (zh) 从山桐子籽油中联产制备亚油酸和a-亚麻酸的方法
WO2025135143A1 (ja) 油脂組成物およびその製造方法
JP2015030685A (ja) 逆相カラムを用いる擬似移動層クロマトグラフィーによる脂溶性物質の分離法およびそのための装置