JP2015518169A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015518169A5 JP2015518169A5 JP2015515158A JP2015515158A JP2015518169A5 JP 2015518169 A5 JP2015518169 A5 JP 2015518169A5 JP 2015515158 A JP2015515158 A JP 2015515158A JP 2015515158 A JP2015515158 A JP 2015515158A JP 2015518169 A5 JP2015518169 A5 JP 2015518169A5
- Authority
- JP
- Japan
- Prior art keywords
- calibrator
- test sample
- components
- sample
- volume
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000523 sample Substances 0.000 claims description 56
- 238000000034 method Methods 0.000 claims description 52
- 238000001962 electrophoresis Methods 0.000 claims description 21
- 238000000926 separation method Methods 0.000 claims description 11
- 102000004895 Lipoproteins Human genes 0.000 claims description 8
- 108090001030 Lipoproteins Proteins 0.000 claims description 8
- 239000012634 fragment Substances 0.000 claims description 8
- 238000011065 in-situ storage Methods 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 8
- 102000009027 Albumins Human genes 0.000 claims description 7
- 108010088751 Albumins Proteins 0.000 claims description 7
- 239000003153 chemical reaction reagent Substances 0.000 claims description 6
- 108010071619 Apolipoproteins Proteins 0.000 claims description 4
- 102000007592 Apolipoproteins Human genes 0.000 claims description 4
- 238000001502 gel electrophoresis Methods 0.000 claims description 4
- 102000007330 LDL Lipoproteins Human genes 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 101710095342 Apolipoprotein B Proteins 0.000 claims description 2
- 102100040202 Apolipoprotein B-100 Human genes 0.000 claims description 2
- 102000009333 Apolipoprotein D Human genes 0.000 claims description 2
- 101710095339 Apolipoprotein E Proteins 0.000 claims description 2
- 102100029470 Apolipoprotein E Human genes 0.000 claims description 2
- 108010025614 Apolipoproteins D Proteins 0.000 claims description 2
- 102100030802 Beta-2-glycoprotein 1 Human genes 0.000 claims description 2
- 108010004103 Chylomicrons Proteins 0.000 claims description 2
- 108010010234 HDL Lipoproteins Proteins 0.000 claims description 2
- 102000015779 HDL Lipoproteins Human genes 0.000 claims description 2
- 108010007622 LDL Lipoproteins Proteins 0.000 claims description 2
- 108010033266 Lipoprotein(a) Proteins 0.000 claims description 2
- 102000057248 Lipoprotein(a) Human genes 0.000 claims description 2
- 108010012071 Lipoprotein-X Proteins 0.000 claims description 2
- 108010062497 VLDL Lipoproteins Proteins 0.000 claims description 2
- 108010023562 beta 2-Glycoprotein I Proteins 0.000 claims description 2
- 239000012472 biological sample Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 230000001590 oxidative effect Effects 0.000 claims description 2
- 238000005406 washing Methods 0.000 claims description 2
- 108010046315 IDL Lipoproteins Proteins 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000007792 addition Methods 0.000 description 1
- 238000004737 colorimetric analysis Methods 0.000 description 1
- 238000012921 fluorescence analysis Methods 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261652608P | 2012-05-29 | 2012-05-29 | |
| US61/652,608 | 2012-05-29 | ||
| US201361779567P | 2013-03-13 | 2013-03-13 | |
| US61/779,567 | 2013-03-13 | ||
| PCT/US2013/043140 WO2013181267A1 (en) | 2012-05-29 | 2013-05-29 | Compsition and method for gel electrophoresis with in-situ clalibration |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017201797A Division JP7082467B2 (ja) | 2012-05-29 | 2017-10-18 | ｉｎ－ｓｉｔｕキャリブレーションを用いるゲル電気泳動用の組成物及び方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015518169A JP2015518169A (ja) | 2015-06-25 |
| JP2015518169A5 true JP2015518169A5 (https=) | 2016-07-14 |
Family
ID=48699256
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515158A Pending JP2015518169A (ja) | 2012-05-29 | 2013-05-29 | ｉｎ−ｓｉｔｕキャリブレーションを用いるゲル電気泳動用の組成物及び方法 |
| JP2017201797A Active JP7082467B2 (ja) | 2012-05-29 | 2017-10-18 | ｉｎ－ｓｉｔｕキャリブレーションを用いるゲル電気泳動用の組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017201797A Active JP7082467B2 (ja) | 2012-05-29 | 2017-10-18 | ｉｎ－ｓｉｔｕキャリブレーションを用いるゲル電気泳動用の組成物及び方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9005419B2 (https=) |
| EP (1) | EP2877846B1 (https=) |
| JP (2) | JP2015518169A (https=) |
| CN (1) | CN104508473B (https=) |
| AU (1) | AU2013267450B2 (https=) |
| BR (1) | BR112014029679A2 (https=) |
| CA (1) | CA2874753C (https=) |
| WO (1) | WO2013181267A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2686740T3 (es) * | 2013-02-28 | 2018-10-19 | Helena Laboratories Corporation | Detección fluorescente in situ de apolipoproteínas de partículas lipídicas en la primera matraz electroforética |
| US9759682B2 (en) | 2013-08-09 | 2017-09-12 | True Health Ip Llc | Applicator comb for gel electrophoresis |
| CA2933605A1 (en) | 2013-12-18 | 2015-06-25 | Philip Guadagno | Lp(a) subform size identification using zonal gel immuno-fixation electrophoresis |
| CA2965172A1 (en) * | 2014-10-21 | 2016-04-28 | Philip Guadagno | Quantitative molar concentration detection of specific apolipoprotein-containing particles present in bodily fluids by using capillary electrophoresis |
| WO2016065021A1 (en) * | 2014-10-21 | 2016-04-28 | True Health Diagnostics, Llc | Lipoprotein particle number from measurements of lipoprotein particle phospholipid concentration in lipoprotein particle membrane bilayer |
| WO2016069639A1 (en) * | 2014-10-27 | 2016-05-06 | True Health Diagnostics, Llc | Lp(a) subform size identification by capillary isoteachophoresis electrophoresis with laser-induced-fluorescence |
| EP3454964B1 (en) * | 2016-05-13 | 2021-06-23 | Agilent Technologies, Inc. | Automated alignment, calibration and standardization of electrophoresis data |
| CN111051873A (zh) * | 2017-07-21 | 2020-04-21 | 海伦娜实验室公司 | 在免疫固定电泳中沉积抗血清的系统和方法 |
| CN113227754B (zh) * | 2018-08-16 | 2025-01-17 | 上海宜晟生物科技有限公司 | 使用智能监测结构的基于图像的测定 |
| US20220099625A1 (en) | 2019-03-02 | 2022-03-31 | Helena Laboratories Corporation | Applicator comb with serrated teeth for gel electrophoresis |
| US20220260596A1 (en) * | 2019-06-27 | 2022-08-18 | Case Western Reserve University | Compositions and methods for blood anemia detection |
| EP3892989A1 (en) * | 2020-04-07 | 2021-10-13 | Ares Trading S.A. | Capillary gel electrophoresis and its use with complex biological molecules |
| WO2023003444A1 (ko) * | 2021-07-23 | 2023-01-26 | 주식회사 씨젠 | 핵산 반응 검출 장치용 캘리브레이션 플레이트를 준비하는 방법 |
| CN113674367B (zh) * | 2021-08-20 | 2024-03-26 | 上海宝藤生物医药科技股份有限公司 | 一种电泳后脂蛋白胆固醇试剂扫描图的预处理方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| JPS6110772A (ja) * | 1984-06-26 | 1986-01-18 | Kyowa Medetsukusu Kk | 生体成分の分析法 |
| US5096557A (en) | 1990-07-11 | 1992-03-17 | Genetype A.G. | Internal standard for electrophoretic separations |
| US5943295A (en) | 1997-02-06 | 1999-08-24 | Automotive Technologies International Inc. | Method for identifying the presence and orientation of an object in a vehicle |
| US5571680A (en) * | 1994-01-21 | 1996-11-05 | Beckman Instruments, Inc. | Homogeneous immunoassays and enzyme based assays of analytes using capillary electrophoresis |
| US5863401A (en) * | 1994-04-14 | 1999-01-26 | Beckman Instruments, Inc. | Simultaneous analysis of analytes by immunoassay using capillary electophoresis with laser induced fluorescence |
| AU2550395A (en) | 1994-06-02 | 1996-01-04 | Perkin-Elmer Corporation, The | Method and apparatus for automated carbohydrate mapping and sequencing |
| US6107045A (en) * | 1994-06-30 | 2000-08-22 | Oklahoma Medical Research Foundation | Antibodies to lipoproteins and apolipoproteins and methods of use thereof |
| US5759375A (en) * | 1996-05-17 | 1998-06-02 | Purdue Research Foundation | Miniaturized disposable gels for DNA analysis |
| GB9624927D0 (en) * | 1996-11-29 | 1997-01-15 | Oxford Glycosciences Uk Ltd | Gels and their use |
| US5843295A (en) | 1996-12-19 | 1998-12-01 | Pharmacia Biotech | Gel electrophoresis well-forming and loading-guide comb |
| US6863791B1 (en) | 2000-09-11 | 2005-03-08 | Spectrumedix Llc | Method for in-situ calibration of electrophoretic analysis systems |
| JP3822454B2 (ja) * | 2001-04-10 | 2006-09-20 | 独立行政法人科学技術振興機構 | リン酸化蛋白質の同定方法 |
| US6982029B2 (en) | 2001-05-07 | 2006-01-03 | Spectramedix Llc | Electrophoretic method and system having internal lane standards for color calibration |
| EP2184369A1 (en) | 2001-07-11 | 2010-05-12 | Applied Biosystems, LLC | Method for normalisation in electrophoresis |
| JP2003279539A (ja) * | 2002-03-20 | 2003-10-02 | Atoo Kk | 穀物タンパク質に対して最適化した電気泳動法及びこれに用いる電気泳動用ゲル、電極緩衝液、試料抽出液。 |
| US7136437B2 (en) * | 2002-07-17 | 2006-11-14 | Lucent Technologies Inc. | Method and apparatus for receiving digital wireless transmissions using multiple-antenna communication schemes |
| US20040106153A1 (en) * | 2002-07-18 | 2004-06-03 | Montana State University | Novel zwitterionic fluorescent dyes for labeling in proteomic and other biological analyses |
| EP1413520B1 (en) | 2002-10-24 | 2006-08-02 | Tetra Laval Holdings & Finance S.A. | Sealing jaw |
| WO2004106923A1 (en) * | 2003-05-28 | 2004-12-09 | Amersham Biosciences Uk Limited | Differential analysis of cell surface proteins on closed membrane structures by labelling with dyes in the presence of an internal standard |
| FR2862134B1 (fr) | 2003-11-12 | 2007-07-27 | Sebia Sa | Analyse et typage de proteines monoclonales par electrophorese capillaire et immunodeplacement |
| JP4742712B2 (ja) | 2005-07-14 | 2011-08-10 | 株式会社島津製作所 | キャピラリー電気泳動方法 |
| JP4822409B2 (ja) * | 2005-10-19 | 2011-11-24 | 独立行政法人産業技術総合研究所 | タンパク質の分析方法 |
| JP4684906B2 (ja) * | 2006-02-09 | 2011-05-18 | 日本メナード化粧品株式会社 | タイトジャンクション形成促進剤 |
| US20090263829A1 (en) * | 2006-03-14 | 2009-10-22 | Washington University In St. Louis | Alzheimer's disease biomarkers and methods of use |
| US20080227209A1 (en) * | 2007-03-14 | 2008-09-18 | David Xing-Fei Deng | Methods, Kits And Devices For Analysis Of Lipoprotein(a) |
| JP2008232927A (ja) * | 2007-03-22 | 2008-10-02 | Sharp Corp | タンパク質濃縮装置及びタンパク質測定装置、これらを用いた空気調整機 |
| KR100857592B1 (ko) * | 2007-06-05 | 2008-09-09 | 충남대학교산학협력단 | ＣｙＤｙｅ를 이용한 새로운 단백질 분석 방법 |
| KR100983475B1 (ko) * | 2008-01-17 | 2010-09-24 | 고려대학교 산학협력단 | 당뇨병성 망막증 진단용 바이오마커 |
| DK2112506T3 (en) * | 2008-04-24 | 2016-05-30 | Max Planck Ges Zur Förderung Der Wissenschaften E V | Method for the automatic high-throughput identification of carbohydrates and carbohydrate composition of the diet patterns and systems should |
| US20090311677A1 (en) * | 2008-06-13 | 2009-12-17 | Andrew Reeves | Identification of contaminating bacteria in industrial ethanol fermentations |
| CN101418350B (zh) * | 2008-10-28 | 2011-06-15 | 南京农业大学 | 利用超低温技术脱除草莓轻型黄边病毒的方法 |
| JP2011039002A (ja) * | 2009-08-18 | 2011-02-24 | Nec Corp | マイクロ電気泳動チップおよび分析方法 |
| US9488666B2 (en) | 2010-08-24 | 2016-11-08 | Helena Laboratories Corporation | Assay for determination of levels of lipoprotein particles in bodily fluids |
| ES2686740T3 (es) | 2013-02-28 | 2018-10-19 | Helena Laboratories Corporation | Detección fluorescente in situ de apolipoproteínas de partículas lipídicas en la primera matraz electroforética |
-
2013
- 2013-05-29 US US13/904,830 patent/US9005419B2/en active Active
- 2013-05-29 CA CA2874753A patent/CA2874753C/en active Active
- 2013-05-29 WO PCT/US2013/043140 patent/WO2013181267A1/en not_active Ceased
- 2013-05-29 AU AU2013267450A patent/AU2013267450B2/en not_active Ceased
- 2013-05-29 EP EP13731539.6A patent/EP2877846B1/en active Active
- 2013-05-29 JP JP2015515158A patent/JP2015518169A/ja active Pending
- 2013-05-29 CN CN201380035181.5A patent/CN104508473B/zh not_active Expired - Fee Related
- 2013-05-29 BR BR112014029679A patent/BR112014029679A2/pt not_active Application Discontinuation
-
2015
- 2015-03-27 US US14/670,609 patent/US10823698B2/en active Active
-
2017
- 2017-10-18 JP JP2017201797A patent/JP7082467B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015518169A5 (https=) | ||
| Tanaka et al. | Estimation of binding constants by capillary electrophoresis | |
| Pavski et al. | Detection of human immunodeficiency virus type 1 reverse transcriptase using aptamers as probes in affinity capillary electrophoresis | |
| Heegaard et al. | Antigen–antibody interactions in capillary electrophoresis | |
| US10753859B2 (en) | Dual wavelength isoelectric focusing for determining drug load in antibody drug conjugates | |
| Moser et al. | Studies of antibody-antigen interactions by capillary electrophoresis: A review | |
| Klepárník et al. | Electrophoresis today and tomorrow: Helping biologists' dreams come true | |
| Liu et al. | Recent advances in affinity capillary electrophoresis (2007) | |
| Horká et al. | Sensitive identification of milk protein allergens using on-line combination of transient isotachophoresis/micellar electrokinetic chromatography and capillary isoelectric focusing in fused silica capillary with roughened part | |
| Srinivas | Introduction to protein electrophoresis | |
| US8859211B2 (en) | Immunodisplacement electrophoresis | |
| US20080227209A1 (en) | Methods, Kits And Devices For Analysis Of Lipoprotein(a) | |
| WO2020237095A1 (en) | Methods for identifying and quantitating host cell protein | |
| US9081006B2 (en) | Rapid homogeneous immunoassay using electrophoresis | |
| US11782023B2 (en) | Ce-western applications for antibody development | |
| JP2020526745A5 (https=) | ||
| Maity et al. | Electrophoretic techniques | |
| US20160320373A1 (en) | Re-Usable Analyte Detector and Methods | |
| Jenkins | Clinical applications of capillary electrophoresis: Status at the new millennium | |
| JP2020523593A (ja) | 可変電界を使用した電気泳動方法 | |
| JP7135163B2 (ja) | 分子プローブの決定方法 | |
| Heegaard et al. | Analysis of proteins in solution using affinity capillary electrophoresis | |
| WO2011036476A1 (en) | Affinity capillary electrophoresis method for assessing a biological interraction of a ligand/receptor pair such as g protein coupled receptor and its targets as well as for drug screening | |
| WO2023089330A1 (en) | Improvements in or relating to a method of analysing a component in a sample | |
| WO2013037732A1 (en) | A method and a system for determining counts of a target cellular entity in a suspension using magnetic levitation |