AU2013267450B2 - Composition and method for gel electrophoresis with in-situ calibration - Google Patents
Composition and method for gel electrophoresis with in-situ calibration Download PDFInfo
- Publication number
- AU2013267450B2 AU2013267450B2 AU2013267450A AU2013267450A AU2013267450B2 AU 2013267450 B2 AU2013267450 B2 AU 2013267450B2 AU 2013267450 A AU2013267450 A AU 2013267450A AU 2013267450 A AU2013267450 A AU 2013267450A AU 2013267450 B2 AU2013267450 B2 AU 2013267450B2
- Authority
- AU
- Australia
- Prior art keywords
- calibrator
- test sample
- sample
- components
- volume
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/417—Systems using cells, i.e. more than one cell and probes with solid electrolytes
- G01N27/4175—Calibrating or checking the analyser
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44743—Introducing samples
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261652608P | 2012-05-29 | 2012-05-29 | |
| US61/652,608 | 2012-05-29 | ||
| US201361779567P | 2013-03-13 | 2013-03-13 | |
| US61/779,567 | 2013-03-13 | ||
| PCT/US2013/043140 WO2013181267A1 (en) | 2012-05-29 | 2013-05-29 | Compsition and method for gel electrophoresis with in-situ clalibration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2013267450A1 AU2013267450A1 (en) | 2014-12-18 |
| AU2013267450B2 true AU2013267450B2 (en) | 2017-07-06 |
Family
ID=48699256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013267450A Ceased AU2013267450B2 (en) | 2012-05-29 | 2013-05-29 | Composition and method for gel electrophoresis with in-situ calibration |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9005419B2 (https=) |
| EP (1) | EP2877846B1 (https=) |
| JP (2) | JP2015518169A (https=) |
| CN (1) | CN104508473B (https=) |
| AU (1) | AU2013267450B2 (https=) |
| BR (1) | BR112014029679A2 (https=) |
| CA (1) | CA2874753C (https=) |
| WO (1) | WO2013181267A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2686740T3 (es) * | 2013-02-28 | 2018-10-19 | Helena Laboratories Corporation | Detección fluorescente in situ de apolipoproteínas de partículas lipídicas en la primera matraz electroforética |
| US9759682B2 (en) | 2013-08-09 | 2017-09-12 | True Health Ip Llc | Applicator comb for gel electrophoresis |
| CA2933605A1 (en) | 2013-12-18 | 2015-06-25 | Philip Guadagno | Lp(a) subform size identification using zonal gel immuno-fixation electrophoresis |
| CA2965172A1 (en) * | 2014-10-21 | 2016-04-28 | Philip Guadagno | Quantitative molar concentration detection of specific apolipoprotein-containing particles present in bodily fluids by using capillary electrophoresis |
| WO2016065021A1 (en) * | 2014-10-21 | 2016-04-28 | True Health Diagnostics, Llc | Lipoprotein particle number from measurements of lipoprotein particle phospholipid concentration in lipoprotein particle membrane bilayer |
| WO2016069639A1 (en) * | 2014-10-27 | 2016-05-06 | True Health Diagnostics, Llc | Lp(a) subform size identification by capillary isoteachophoresis electrophoresis with laser-induced-fluorescence |
| EP3454964B1 (en) * | 2016-05-13 | 2021-06-23 | Agilent Technologies, Inc. | Automated alignment, calibration and standardization of electrophoresis data |
| CN111051873A (zh) * | 2017-07-21 | 2020-04-21 | 海伦娜实验室公司 | 在免疫固定电泳中沉积抗血清的系统和方法 |
| CN113227754B (zh) * | 2018-08-16 | 2025-01-17 | 上海宜晟生物科技有限公司 | 使用智能监测结构的基于图像的测定 |
| US20220099625A1 (en) | 2019-03-02 | 2022-03-31 | Helena Laboratories Corporation | Applicator comb with serrated teeth for gel electrophoresis |
| US20220260596A1 (en) * | 2019-06-27 | 2022-08-18 | Case Western Reserve University | Compositions and methods for blood anemia detection |
| EP3892989A1 (en) * | 2020-04-07 | 2021-10-13 | Ares Trading S.A. | Capillary gel electrophoresis and its use with complex biological molecules |
| WO2023003444A1 (ko) * | 2021-07-23 | 2023-01-26 | 주식회사 씨젠 | 핵산 반응 검출 장치용 캘리브레이션 플레이트를 준비하는 방법 |
| CN113674367B (zh) * | 2021-08-20 | 2024-03-26 | 上海宝藤生物医药科技股份有限公司 | 一种电泳后脂蛋白胆固醇试剂扫描图的预处理方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1995033989A1 (en) * | 1994-06-02 | 1995-12-14 | Perkin-Elmer Corporation | Method and apparatus for automated carbohydrate mapping and sequencing |
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| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| JPS6110772A (ja) * | 1984-06-26 | 1986-01-18 | Kyowa Medetsukusu Kk | 生体成分の分析法 |
| US5096557A (en) | 1990-07-11 | 1992-03-17 | Genetype A.G. | Internal standard for electrophoretic separations |
| US5943295A (en) | 1997-02-06 | 1999-08-24 | Automotive Technologies International Inc. | Method for identifying the presence and orientation of an object in a vehicle |
| US5571680A (en) * | 1994-01-21 | 1996-11-05 | Beckman Instruments, Inc. | Homogeneous immunoassays and enzyme based assays of analytes using capillary electrophoresis |
| US5863401A (en) * | 1994-04-14 | 1999-01-26 | Beckman Instruments, Inc. | Simultaneous analysis of analytes by immunoassay using capillary electophoresis with laser induced fluorescence |
| US6107045A (en) * | 1994-06-30 | 2000-08-22 | Oklahoma Medical Research Foundation | Antibodies to lipoproteins and apolipoproteins and methods of use thereof |
| US5759375A (en) * | 1996-05-17 | 1998-06-02 | Purdue Research Foundation | Miniaturized disposable gels for DNA analysis |
| GB9624927D0 (en) * | 1996-11-29 | 1997-01-15 | Oxford Glycosciences Uk Ltd | Gels and their use |
| US5843295A (en) | 1996-12-19 | 1998-12-01 | Pharmacia Biotech | Gel electrophoresis well-forming and loading-guide comb |
| US6863791B1 (en) | 2000-09-11 | 2005-03-08 | Spectrumedix Llc | Method for in-situ calibration of electrophoretic analysis systems |
| JP3822454B2 (ja) * | 2001-04-10 | 2006-09-20 | 独立行政法人科学技術振興機構 | リン酸化蛋白質の同定方法 |
| US6982029B2 (en) | 2001-05-07 | 2006-01-03 | Spectramedix Llc | Electrophoretic method and system having internal lane standards for color calibration |
| EP2184369A1 (en) | 2001-07-11 | 2010-05-12 | Applied Biosystems, LLC | Method for normalisation in electrophoresis |
| JP2003279539A (ja) * | 2002-03-20 | 2003-10-02 | Atoo Kk | 穀物タンパク質に対して最適化した電気泳動法及びこれに用いる電気泳動用ゲル、電極緩衝液、試料抽出液。 |
| US7136437B2 (en) * | 2002-07-17 | 2006-11-14 | Lucent Technologies Inc. | Method and apparatus for receiving digital wireless transmissions using multiple-antenna communication schemes |
| US20040106153A1 (en) * | 2002-07-18 | 2004-06-03 | Montana State University | Novel zwitterionic fluorescent dyes for labeling in proteomic and other biological analyses |
| EP1413520B1 (en) | 2002-10-24 | 2006-08-02 | Tetra Laval Holdings & Finance S.A. | Sealing jaw |
| WO2004106923A1 (en) * | 2003-05-28 | 2004-12-09 | Amersham Biosciences Uk Limited | Differential analysis of cell surface proteins on closed membrane structures by labelling with dyes in the presence of an internal standard |
| FR2862134B1 (fr) | 2003-11-12 | 2007-07-27 | Sebia Sa | Analyse et typage de proteines monoclonales par electrophorese capillaire et immunodeplacement |
| JP4742712B2 (ja) | 2005-07-14 | 2011-08-10 | 株式会社島津製作所 | キャピラリー電気泳動方法 |
| JP4822409B2 (ja) * | 2005-10-19 | 2011-11-24 | 独立行政法人産業技術総合研究所 | タンパク質の分析方法 |
| JP4684906B2 (ja) * | 2006-02-09 | 2011-05-18 | 日本メナード化粧品株式会社 | タイトジャンクション形成促進剤 |
| US20090263829A1 (en) * | 2006-03-14 | 2009-10-22 | Washington University In St. Louis | Alzheimer's disease biomarkers and methods of use |
| US20080227209A1 (en) * | 2007-03-14 | 2008-09-18 | David Xing-Fei Deng | Methods, Kits And Devices For Analysis Of Lipoprotein(a) |
| JP2008232927A (ja) * | 2007-03-22 | 2008-10-02 | Sharp Corp | タンパク質濃縮装置及びタンパク質測定装置、これらを用いた空気調整機 |
| KR100857592B1 (ko) * | 2007-06-05 | 2008-09-09 | 충남대학교산학협력단 | CyDye를 이용한 새로운 단백질 분석 방법 |
| KR100983475B1 (ko) * | 2008-01-17 | 2010-09-24 | 고려대학교 산학협력단 | 당뇨병성 망막증 진단용 바이오마커 |
| DK2112506T3 (en) * | 2008-04-24 | 2016-05-30 | Max Planck Ges Zur Förderung Der Wissenschaften E V | Method for the automatic high-throughput identification of carbohydrates and carbohydrate composition of the diet patterns and systems should |
| US20090311677A1 (en) * | 2008-06-13 | 2009-12-17 | Andrew Reeves | Identification of contaminating bacteria in industrial ethanol fermentations |
| CN101418350B (zh) * | 2008-10-28 | 2011-06-15 | 南京农业大学 | 利用超低温技术脱除草莓轻型黄边病毒的方法 |
| JP2011039002A (ja) * | 2009-08-18 | 2011-02-24 | Nec Corp | マイクロ電気泳動チップおよび分析方法 |
| US9488666B2 (en) | 2010-08-24 | 2016-11-08 | Helena Laboratories Corporation | Assay for determination of levels of lipoprotein particles in bodily fluids |
| ES2686740T3 (es) | 2013-02-28 | 2018-10-19 | Helena Laboratories Corporation | Detección fluorescente in situ de apolipoproteínas de partículas lipídicas en la primera matraz electroforética |
-
2013
- 2013-05-29 US US13/904,830 patent/US9005419B2/en active Active
- 2013-05-29 CA CA2874753A patent/CA2874753C/en active Active
- 2013-05-29 WO PCT/US2013/043140 patent/WO2013181267A1/en not_active Ceased
- 2013-05-29 AU AU2013267450A patent/AU2013267450B2/en not_active Ceased
- 2013-05-29 EP EP13731539.6A patent/EP2877846B1/en active Active
- 2013-05-29 JP JP2015515158A patent/JP2015518169A/ja active Pending
- 2013-05-29 CN CN201380035181.5A patent/CN104508473B/zh not_active Expired - Fee Related
- 2013-05-29 BR BR112014029679A patent/BR112014029679A2/pt not_active Application Discontinuation
-
2015
- 2015-03-27 US US14/670,609 patent/US10823698B2/en active Active
-
2017
- 2017-10-18 JP JP2017201797A patent/JP7082467B2/ja active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995033989A1 (en) * | 1994-06-02 | 1995-12-14 | Perkin-Elmer Corporation | Method and apparatus for automated carbohydrate mapping and sequencing |
Non-Patent Citations (3)
| Title |
|---|
| GOUX, A. et al., 'Capillary Gel Electrophoresis Analysis of Apolipoproteins A-I and A-II in Human High-Density Lipoproteins', ANALYTICAL BIOCHEMISTRY, 1994, vol. 218, no. 2, pages 320-324 * |
| SCHERER, R. et al., 'Plasma protein profiling: The diagnostic evaluation of disorders in plasma protein composition by a new immunoelectrophoretic method', CLINICA CHIMICA ACTA, 1976, vol. 66, no. 3, pages 417-433 * |
| STOCKS, J. et al., 'Analysis of high density lipoprotein apolipoproteins by capillary zone and capillary SDS gel electrophoresis', JOURNAL OF LIPID RESEARCH, 1998, vol. 39, no. 1, pages 218-219 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104508473B (zh) | 2017-10-13 |
| US20130319864A1 (en) | 2013-12-05 |
| WO2013181267A8 (en) | 2014-12-18 |
| JP7082467B2 (ja) | 2022-06-08 |
| US10823698B2 (en) | 2020-11-03 |
| EP2877846A1 (en) | 2015-06-03 |
| WO2013181267A1 (en) | 2013-12-05 |
| US20150268193A1 (en) | 2015-09-24 |
| CA2874753A1 (en) | 2013-12-05 |
| JP2015518169A (ja) | 2015-06-25 |
| CN104508473A (zh) | 2015-04-08 |
| JP2018028549A (ja) | 2018-02-22 |
| AU2013267450A1 (en) | 2014-12-18 |
| CA2874753C (en) | 2023-02-28 |
| BR112014029679A2 (pt) | 2017-06-27 |
| US9005419B2 (en) | 2015-04-14 |
| EP2877846B1 (en) | 2026-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: TRUE HEALTH IP LLC Free format text: FORMER APPLICANT(S): HEALTH DIAGNOSTIC LABORATORY, INC. |
|
| FGA | Letters patent sealed or granted (standard patent) | ||
| PC | Assignment registered |
Owner name: HELENA LABORATORIES CORPORATION Free format text: FORMER OWNER(S): TRUE HEALTH IP LLC |
|
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |