JP2022527225A5 - - Google Patents

Info

Publication number
JP2022527225A5
JP2022527225A5 JP2021560630A JP2021560630A JP2022527225A5 JP 2022527225 A5 JP2022527225 A5 JP 2022527225A5 JP 2021560630 A JP2021560630 A JP 2021560630A JP 2021560630 A JP2021560630 A JP 2021560630A JP 2022527225 A5 JP2022527225 A5 JP 2022527225A5
Authority
JP
Japan
Prior art keywords
nanopores
substrate
nanosensor chip
molecule
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021560630A
Other languages
English (en)
Japanese (ja)
Other versions
JP7627819B2 (ja
JP2022527225A (ja
Filing date
Publication date
Priority claimed from US16/383,491 external-priority patent/US20200326325A1/en
Application filed filed Critical
Publication of JP2022527225A publication Critical patent/JP2022527225A/ja
Publication of JP2022527225A5 publication Critical patent/JP2022527225A5/ja
Application granted granted Critical
Publication of JP7627819B2 publication Critical patent/JP7627819B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021560630A 2019-04-12 2020-04-09 複合ナノ細孔を備えるナノセンサチップ Active JP7627819B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/383,491 US20200326325A1 (en) 2019-04-12 2019-04-12 Nanosensor chip with compound nanopores
US16/383,491 2019-04-12
PCT/US2020/027550 WO2020210548A1 (en) 2019-04-12 2020-04-09 Nanosensor chip with compound nanopores

Publications (3)

Publication Number Publication Date
JP2022527225A JP2022527225A (ja) 2022-05-31
JP2022527225A5 true JP2022527225A5 (https=) 2023-04-17
JP7627819B2 JP7627819B2 (ja) 2025-02-07

Family

ID=72747695

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021560630A Active JP7627819B2 (ja) 2019-04-12 2020-04-09 複合ナノ細孔を備えるナノセンサチップ

Country Status (7)

Country Link
US (2) US20200326325A1 (https=)
EP (1) EP3953043B1 (https=)
JP (1) JP7627819B2 (https=)
CN (1) CN114269475B (https=)
GB (1) GB2593071B (https=)
TW (1) TWI752461B (https=)
WO (1) WO2020210548A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200326325A1 (en) 2019-04-12 2020-10-15 Lisa Diamond Nanosensor chip with compound nanopores
WO2021252772A1 (en) * 2020-06-12 2021-12-16 Analog Devices, Inc. Sample testing device
WO2022076861A1 (en) * 2020-10-08 2022-04-14 Lmx Medtech Llc Microwell microelectrode filtration sensor
CN112522085B (zh) * 2020-12-01 2022-05-31 合肥国研汉因检测科技有限公司 一种基于固态纳米孔的基因检测装置
CN115121303B (zh) * 2022-07-01 2024-01-02 深圳市梅丽纳米孔科技有限公司 用于纳米孔传感器的微流体装置及其组装方法
GB2637334A (en) * 2024-01-18 2025-07-23 Jesus Jara Fornerod Maximiliano A nanoporous electrode for electrochemical detection of nucleic acids
US20260079150A1 (en) * 2024-09-16 2026-03-19 Oxbridge Clinical Inc. Methods and apparatus for simultaneous identification and quantification of a microbe

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2178555A5 (https=) * 1972-12-21 1973-11-09 Petroles Cie Francaise
ATE214633T1 (de) * 1993-10-28 2002-04-15 Houston Advanced Res Ct Mikrofabriziertes poröses durchflussgerät
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
JP3834519B2 (ja) 2001-03-21 2006-10-18 オリンパス株式会社 生化学的検査方法
WO2004085609A2 (en) * 2003-02-28 2004-10-07 Brown University Nanopores, methods for using same, methods for making same and methods for characterizing biomolecules using same
US7250115B2 (en) 2003-06-12 2007-07-31 Agilent Technologies, Inc Nanopore with resonant tunneling electrodes
US7851203B2 (en) * 2003-10-01 2010-12-14 Lawrence Livermore National Security, Llc Functionalized apertures for the detection of chemical and biological materials
CN101415487A (zh) 2003-12-08 2009-04-22 纽约州立大学研究基金会 传感器应用中的位点选择性标记和模板分子印记聚合物
US20060210995A1 (en) 2005-03-15 2006-09-21 Joyce Timothy H Nanopore analysis systems and methods of using nanopore devices
US9632073B2 (en) 2012-04-02 2017-04-25 Lux Bio Group, Inc. Apparatus and method for molecular separation, purification, and sensing
US8592225B2 (en) 2006-09-28 2013-11-26 The Board Of Trustees Of The Leland Stanford Junior University Array-based bioactivated nanopore devices
US9034637B2 (en) * 2007-04-25 2015-05-19 Nxp, B.V. Apparatus and method for molecule detection using nanopores
WO2009020682A2 (en) 2007-05-08 2009-02-12 The Trustees Of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
US8940142B2 (en) 2008-05-05 2015-01-27 The Regents Of The University Of California Functionalized nanopipette biosensor
WO2011017077A2 (en) * 2009-07-27 2011-02-10 Trustees Of Boston University Nanochannel-based sensor system with controlled sensitivity
IT1398771B1 (it) * 2009-09-04 2013-03-18 Istituto Naz Per La Ricerca Sul Cancro Chip nanoforato di nitruro di silicio per l'analisi di profili di espressione genica e relativi biosensori.
RU2556800C2 (ru) * 2010-06-14 2015-07-20 Ф.Хоффманн-Ля Рош Аг Пептиды, проникающие в клетки, и их применения
US8535544B2 (en) 2010-07-26 2013-09-17 International Business Machines Corporation Structure and method to form nanopore
GB201020503D0 (en) 2010-12-03 2011-01-19 Imp Innovations Ltd Nanopore devices
EP2678669A1 (en) * 2011-02-23 2014-01-01 The Trustees of Columbia University in the City of New York Systems and methods for single-molecule detection using nanopores
WO2012122029A2 (en) 2011-03-04 2012-09-13 The Regents Of The University Of California Nanopore device for reversible ion and molecule sensing or migration
ITRM20110252A1 (it) * 2011-05-23 2012-11-24 Istituto Naz Per La Ricerca S Ul Cancro Metodo di analisi di singola molecola mediante rilevazione delle collisioni di una molecola target su nanopori funzionalizzati.
CA2938661A1 (en) 2011-10-21 2013-04-25 Stemgenics, Inc Functionalized nanoparticles for intracellular delivery of biologically active molecules
IN2014DN06796A (https=) 2012-02-15 2015-05-22 Oxford Nanopore Tech Ltd
US9341592B2 (en) 2012-04-09 2016-05-17 Bharath Takulapalli Field effect transistor, device including the transistor, and methods of forming and using same
EP3674412A1 (en) * 2012-06-20 2020-07-01 The Trustees of Columbia University in the City of New York Nucleic acid sequencing by nanopore detection of tag molecules
WO2014072703A1 (en) 2012-11-06 2014-05-15 Oxford Nanopore Technologies Limited Quadruplex method
US20150346188A1 (en) 2012-12-21 2015-12-03 Ibis Biosciences, Inc. Stabilized nanopore and micropore structures and methods for making and using the same
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
US9372171B2 (en) * 2013-04-30 2016-06-21 International Business Machines Corporation Nanopore sensor for detecting molecular interactions
JP6461943B2 (ja) * 2013-10-23 2019-01-30 ジェニア・テクノロジーズ・インコーポレイテッド ナノポアを備えた高速分子検知
WO2015077751A1 (en) 2013-11-25 2015-05-28 Northeastern University Freestanding ultra thin membranes and transfer-free fabrication thereof
JP6636455B2 (ja) 2014-01-24 2020-01-29 国立大学法人大阪大学 生体分子配列決定装置、システムおよび方法
US10047392B2 (en) * 2014-02-21 2018-08-14 Northeastern University Fluorescence-based analysis of biopolymers using nanopores
CN107002126B (zh) 2014-10-24 2021-05-25 昆塔波尔公司 使用纳米结构阵列的聚合物的高效光学分析
EP3227228A4 (en) * 2014-12-01 2018-08-15 Cornell University Nanopore-containing substrates with aligned nanoscale electronic elements and methods of making and using same
JP6283305B2 (ja) * 2014-12-04 2018-02-21 株式会社日立ハイテクノロジーズ 生体分子測定装置及び生体分子測定方法
US9658190B2 (en) 2014-12-18 2017-05-23 Genia Technologies, Inc. Printed electrode
CN107135657A (zh) * 2014-12-31 2017-09-05 卡尤迪生物科技（北京）有限公司 使用纳米孔和复合部分的核酸分子检测
US20180045675A1 (en) 2015-02-25 2018-02-15 The Regents Of The University Of California Single-cell intracellular nano-ph probes
GB201510322D0 (en) 2015-06-12 2015-07-29 Imp Innovations Ltd Apparatus and method
WO2017100683A1 (en) 2015-12-09 2017-06-15 Stemgenics, Inc. Differential drug screening using pluripotent stem cells induced with functionalized nanoparticles
JP6579948B2 (ja) 2015-12-24 2019-09-25 株式会社日立ハイテクノロジーズ 生体ポリマを分析するための測定試薬及び分析デバイス
WO2017184790A1 (en) 2016-04-19 2017-10-26 Takulapalli Bharath Nanopore sensor, structure and device including the sensor, and methods of forming and using same
US9816988B1 (en) 2016-08-10 2017-11-14 Multerra Bio, Inc. Apparatuses and methods for detecting molecules and binding energy
AU2018290975B2 (en) 2017-06-29 2024-10-03 President And Fellows Of Harvard College Deterministic stepping of polymers through a nanopore
JP6796561B2 (ja) * 2017-08-02 2020-12-09 株式会社日立ハイテク 生体試料分析装置、及び方法
JP6453960B1 (ja) 2017-08-31 2019-01-16 株式会社東芝 検出装置および検出方法
CN108279312B (zh) * 2018-03-08 2021-06-01 冯建东 一种基于纳米孔的蛋白质组学分析装置及血清检测方法及应用
US11099170B2 (en) * 2018-06-13 2021-08-24 The Board Of Trustees Of The University Of Illinois Parallel DNA detection by solid-state multi-pore systems and associated methods
KR102826391B1 (ko) * 2018-07-27 2025-06-26 팔로젠 인코포레이티드 나노포어 디바이스 및 이를 사용하여 하전된 입자들을 검출하는 방법
US20200326325A1 (en) 2019-04-12 2020-10-15 Lisa Diamond Nanosensor chip with compound nanopores

Similar Documents

Publication Publication Date Title
JP2022527225A5 (https=)
JP6928103B2 (ja) 少なくとも１つの流体試料中の少なくとも１つの分析物を検出する分析物検出器
GB2593071A (en) Nanosensor chip with compound nanopores
Wu et al. Label-free detection of DNA using a light-addressable potentiometric sensor modified with a positively charged polyelectrolyte layer
JP6133780B2 (ja) 汎捕捉性の結合領域を備えている多方向マイクロ流体デバイス、及びその使用方法
de Vasconcelos et al. Potential of a simplified measurement scheme and device structure for a low cost label-free point-of-care capacitive biosensor
JP2015518169A5 (https=)
Al-Qaoud et al. The development of an electrochemical immunosensor utilizing chicken IgY anti-spike antibody for the detection of SARS-CoV-2
SE533515C2 (sv) Analysförfarande för samtidig analys av flera analyter
CN112020645A (zh) 基于多孔电极的生物传感器
Na et al. On-chip paper electrophoresis for ultrafast screening of infectious diseases
Xie et al. A ten-minute, single step, label-free, sample-to-answer assay for qualitative detection of cytokines in serum at femtomolar levels
US20150355133A1 (en) Nano-well based electrical immunoassays
Hanifa Lestari et al. Label-free and label-based electrochemical detection of disease biomarker proteins
JP5766714B2 (ja) インピーダンス測定に基づく多重インピーダンス解析システムを使用する方法
Mahmoodi et al. Multiwell plate impedance analysis of a nanowell array sensor for label-free detection of cytokines in mouse serum
Sanguino et al. Interdigitated capacitive immunosensors with PVDF immobilization layers
Jetzschmann et al. Label-free MIP sensors for protein biomarkers
Kongsuphol et al. Miniaturized electrophoresis electrochemical protein sensor (MEEPS) for multiplexed protein detections
KR20090062591A (ko) 유전영동 임피던스를 이용한 센싱장치 및 센싱방법
JP2025000817A (ja) 半導体ベースのバイオセンサとその検出方法
Kazimierczak et al. Immunosensors for human cardiac troponins and CRP, in particular amperometric cTnI immunosensor
JP4918237B2 (ja) 生体の定量方法
WO2023006865A1 (en) Biosensor for the detection of hepatitis c virus
US20160320373A1 (en) Re-Usable Analyte Detector and Methods