JP2015517577A5 - - Google Patents
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- Publication number
- JP2015517577A5 JP2015517577A5 JP2015514140A JP2015514140A JP2015517577A5 JP 2015517577 A5 JP2015517577 A5 JP 2015517577A5 JP 2015514140 A JP2015514140 A JP 2015514140A JP 2015514140 A JP2015514140 A JP 2015514140A JP 2015517577 A5 JP2015517577 A5 JP 2015517577A5
- Authority
- JP
- Japan
- Prior art keywords
- aryl
- het
- nhr
- cycloalkyl
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261650039P | 2012-05-22 | 2012-05-22 | |
| US61/650,039 | 2012-05-22 | ||
| US201361757876P | 2013-01-29 | 2013-01-29 | |
| US61/757,876 | 2013-01-29 | ||
| PCT/US2013/042148 WO2013177241A1 (en) | 2012-05-22 | 2013-05-22 | Method for synthesizing cycloalkanyl(b}indoles, cycloalkanyl(b) benzofurans, cycloalkanyl(b)benzothiophenes, compounds and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015517577A JP2015517577A (ja) | 2015-06-22 |
| JP2015517577A5 true JP2015517577A5 (enExample) | 2016-07-07 |
| JP6653573B2 JP6653573B2 (ja) | 2020-02-26 |
Family
ID=49624309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015514140A Active JP6653573B2 (ja) | 2012-05-22 | 2013-05-22 | シクロアルカニル[b]インドール、シクロアルカニル[b]ベンゾフラン、シクロアルカニル[b]ベンゾチオフェンを合成するための方法、化合物および使用の方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9598365B2 (enExample) |
| EP (1) | EP2887804B1 (enExample) |
| JP (1) | JP6653573B2 (enExample) |
| WO (1) | WO2013177241A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016094688A1 (en) | 2014-12-10 | 2016-06-16 | Massachusetts Institute Of Technology | Fused 1,3-azole derivatives useful for the treatment of proliferative diseases |
| WO2016172496A1 (en) | 2015-04-23 | 2016-10-27 | Constellation Pharmaceuticals, Inc. | Lsd1 inhibitors and uses thereof |
| MX391259B (es) | 2015-10-14 | 2025-03-21 | X Therma Inc | Composiciones y métodos para reducir la formación de cristales de hielo. |
| EP3416950A1 (en) | 2016-02-16 | 2018-12-26 | Massachusetts Institute of Technology | Max binders as myc modulators and uses thereof |
| HUE063848T2 (hu) | 2016-10-26 | 2024-02-28 | Constellation Pharmaceuticals Inc | LSD1 gátlók és gyógyászati alkalmazásaik |
| WO2018129205A1 (en) * | 2017-01-04 | 2018-07-12 | The Trustees Of Dartmouth College | Methods of inhibiting pcsk9 |
| KR20230031322A (ko) | 2020-06-27 | 2023-03-07 | 크레센타 바이오사이언시즈 | 세포 물질대사를 조정하는 화합물의 조성물 및 사용 방법 |
| US12138243B2 (en) | 2021-12-31 | 2024-11-12 | Crescenta Biosciences | Antiviral use of FABP4 modulating compounds |
| CN120590310B (zh) * | 2025-08-07 | 2025-10-28 | 昆明医科大学 | 一种吲哚-3-芳基酮衍生物及其制备方法和应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3696118A (en) * | 1970-04-22 | 1972-10-03 | Marcel K Eberle | SPIRO NORBORNANE 6,9-METHANOCYCLOHEPT(b)INDOLES |
| US3931288A (en) * | 1972-03-13 | 1976-01-06 | Hoffmann-La Roche Inc. | Alkyl esters of 4-chlorophenoxy-4-oxo-cycloalkyl-carboxylic acid |
| US4755505A (en) * | 1987-08-18 | 1988-07-05 | American Home Products Corporation | 1-[2-(dialkylamino)alkyl]-4,5-dihydro-4-(aryl)-1-benzazocine-2,6(1H,3H)-diones as anti-arrhythmic agents |
| AU3840000A (en) | 1999-04-20 | 2000-11-02 | Meiji Seika Kaisha Ltd. | Tricyclic compounds |
| EP1330457B1 (en) * | 2000-11-03 | 2004-10-20 | Wyeth | Cyclopenta[b][1,4] diazepino[6,7,1-hi]indoles as 5ht2c antagonists |
| TW200307540A (en) | 2002-04-25 | 2003-12-16 | Wyeth Corp | [1, 4]Diazocino[7, 8, 1-hi] indole derivatives as antipsychotic and antiobesity agents |
| WO2003097598A1 (en) | 2002-05-16 | 2003-11-27 | Shionogi & Co., Ltd. | Compound exhibiting pgd 2 receptor antagonism |
| WO2004063156A1 (en) | 2003-01-08 | 2004-07-29 | Biovitrum Ab | Novel indole derivates as fabp-4 inhibitors |
| WO2004069831A1 (en) * | 2003-02-10 | 2004-08-19 | Glenmark Pharmaceuticals Ltd. | Tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation |
| US7351733B2 (en) | 2003-06-10 | 2008-04-01 | Smithkline Beecham Corporation | Tetrahydrocarbazole derivatives and their pharmaceutical use |
| WO2005023245A1 (en) | 2003-08-26 | 2005-03-17 | Smithkline Beecham Corporation | Novel cycloalkyl’b! condensed indoles |
| WO2005094833A1 (en) | 2004-03-31 | 2005-10-13 | Council Of Scientific And Industrial Research | Novel n-substituted dihydrobenzothiepino, dihydrobenzoxepino and tetrahydro benzocyclohepta indoles as selective estrogen receptor modulators |
| SI1796664T1 (sl) | 2004-09-20 | 2014-02-28 | Janssen Pharmaceutica N.V. | Novi tetraciklični derivati, ki vsebujejo heteroatome, in so uporabni kot modulatorji receptorja spolnega steoidnega hormona |
| CN101072780B (zh) | 2004-09-20 | 2010-06-23 | 詹森药业有限公司 | 用作类固醇性激素受体调节剂的新的含杂原子的四环衍生物 |
| EP1817295B1 (en) | 2004-11-18 | 2012-11-07 | Synta Pharmaceuticals Corp. | Triazole compounds that modulate hsp90 activity |
| WO2006121466A2 (en) | 2004-11-22 | 2006-11-16 | Smithkline Beecham Corporation | Hcv inhibitors |
| WO2006121467A2 (en) | 2004-11-22 | 2006-11-16 | Smithkline Beecham Corporation | Tetrahydrocarbazole derivatives for treating flaviridae viruses |
| RU2008108903A (ru) | 2005-08-12 | 2009-09-20 | Джинентех, Инк. (US) | Пентациклический ингибитор киназы |
| US7662831B2 (en) | 2006-07-27 | 2010-02-16 | Wyeth Llc | Tetracyclic indoles as potassium channel modulators |
| CA2659425C (en) | 2006-08-17 | 2017-06-20 | Synta Pharmaceuticals Corp. | Triazole compounds that modulate hsp90 activity |
| BRPI0906245A2 (pt) | 2008-03-24 | 2015-06-30 | Medivation Technologies Inc | Composto, método para tratar um distúrbio cognitivo, psicótico, mediado por neurotransmissor ou um distúrbio neuronal em indivíduo, uso de um composto, composição farmacêutica e kit |
| AR073701A1 (es) | 2008-09-29 | 2010-11-24 | Abbott Lab | Derivados de indol y de indolicina, metodos para su preparacion, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades neurodegenerativas. |
| WO2010054382A1 (en) | 2008-11-10 | 2010-05-14 | Elixir Pharmaceuticals, Inc. | Compounds, compositions, and methods for treating malaria or leishmaniasis |
| JP5497284B2 (ja) * | 2008-12-08 | 2014-05-21 | ユー・ディー・シー アイルランド リミテッド | 白色有機電界発光素子 |
| JP5913091B2 (ja) | 2009-03-27 | 2016-04-27 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | C型肝炎ウイルス複製の阻害剤 |
| US8629158B2 (en) | 2009-07-01 | 2014-01-14 | Albany Molecular Research, Inc. | Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
| WO2011044134A1 (en) | 2009-10-05 | 2011-04-14 | Albany Molecular Research, Inc. | Epiminocycloalkyl(b)indole derivatives as serotonin sub-type 6 (5-ht6) modulators and uses thereof |
| US8778959B2 (en) | 2009-12-17 | 2014-07-15 | Abbvie Inc. | AZA-bridged ring-fused indoles and indolines |
| GB201016411D0 (en) * | 2010-09-30 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method for cancer |
| WO2012054526A2 (en) * | 2010-10-19 | 2012-04-26 | Elcelyx Therapeutics, Inc. | Chemosensory receptor ligand-based therapies |
-
2013
- 2013-05-22 WO PCT/US2013/042148 patent/WO2013177241A1/en not_active Ceased
- 2013-05-22 JP JP2015514140A patent/JP6653573B2/ja active Active
- 2013-05-22 EP EP13794752.9A patent/EP2887804B1/en not_active Not-in-force
-
2014
- 2014-11-10 US US14/537,154 patent/US9598365B2/en not_active Expired - Fee Related
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