JP2015513312A5 - - Google Patents

Download PDF

Info

Publication number
JP2015513312A5
JP2015513312A5 JP2014547503A JP2014547503A JP2015513312A5 JP 2015513312 A5 JP2015513312 A5 JP 2015513312A5 JP 2014547503 A JP2014547503 A JP 2014547503A JP 2014547503 A JP2014547503 A JP 2014547503A JP 2015513312 A5 JP2015513312 A5 JP 2015513312A5
Authority
JP
Japan
Prior art keywords
pth
binding polypeptide
seq
collagen
polypeptide segment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014547503A
Other languages
English (en)
Japanese (ja)
Other versions
JP6366507B2 (ja
JP2015513312A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/069831 external-priority patent/WO2013090770A2/en
Publication of JP2015513312A publication Critical patent/JP2015513312A/ja
Publication of JP2015513312A5 publication Critical patent/JP2015513312A5/ja
Application granted granted Critical
Publication of JP6366507B2 publication Critical patent/JP6366507B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014547503A 2011-12-14 2012-12-14 コラーゲン結合タンパク質による治療剤の送達 Active JP6366507B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161570620P 2011-12-14 2011-12-14
US61/570,620 2011-12-14
US201261596869P 2012-02-09 2012-02-09
US61/596,869 2012-02-09
PCT/US2012/069831 WO2013090770A2 (en) 2011-12-14 2012-12-14 Delivery of therapeutic agents by a collagen binding protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018038513A Division JP6697019B2 (ja) 2011-12-14 2018-03-05 コラーゲン結合タンパク質による治療剤の送達

Publications (3)

Publication Number Publication Date
JP2015513312A JP2015513312A (ja) 2015-05-07
JP2015513312A5 true JP2015513312A5 (https=) 2016-02-04
JP6366507B2 JP6366507B2 (ja) 2018-08-01

Family

ID=48613370

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2014547503A Active JP6366507B2 (ja) 2011-12-14 2012-12-14 コラーゲン結合タンパク質による治療剤の送達
JP2018038513A Active JP6697019B2 (ja) 2011-12-14 2018-03-05 コラーゲン結合タンパク質による治療剤の送達
JP2020000376A Pending JP2020073554A (ja) 2011-12-14 2020-01-06 コラーゲン結合タンパク質による治療剤の送達
JP2021172953A Active JP7327765B2 (ja) 2011-12-14 2021-10-22 コラーゲン結合タンパク質による治療剤の送達
JP2023121669A Pending JP2023153154A (ja) 2011-12-14 2023-07-26 コラーゲン結合タンパク質による治療剤の送達

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2018038513A Active JP6697019B2 (ja) 2011-12-14 2018-03-05 コラーゲン結合タンパク質による治療剤の送達
JP2020000376A Pending JP2020073554A (ja) 2011-12-14 2020-01-06 コラーゲン結合タンパク質による治療剤の送達
JP2021172953A Active JP7327765B2 (ja) 2011-12-14 2021-10-22 コラーゲン結合タンパク質による治療剤の送達
JP2023121669A Pending JP2023153154A (ja) 2011-12-14 2023-07-26 コラーゲン結合タンパク質による治療剤の送達

Country Status (7)

Country Link
US (3) US9579273B2 (https=)
EP (4) EP2790717B1 (https=)
JP (5) JP6366507B2 (https=)
CA (2) CA2859412C (https=)
DK (2) DK2790717T3 (https=)
ES (3) ES2975215T3 (https=)
WO (1) WO2013090770A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2930681C (en) 2007-04-09 2019-10-15 The Board Of Trustees Of The University Of Arkansas Fusion protein of collagen-binding domain and parathyroid hormone
US9579273B2 (en) 2011-12-14 2017-02-28 The Kitasato Institute Delivery of therapeutic agents by a collagen binding protein
WO2013120060A1 (en) 2012-02-09 2013-08-15 The Board Of Trustees Of The University Of Arkansas Delivery of therapeutic agents by a collagen binding protein
WO2018148573A1 (en) * 2017-02-10 2018-08-16 The Board Of Trustees Of The University Of Arkansas Collagen-binding agent compositions and methods of using the same
GB201706781D0 (en) 2017-04-28 2017-06-14 Univ Sheffield Parathyroid hormone fusion polypeptide
KR101964376B1 (ko) * 2017-09-29 2019-04-01 주식회사 나이벡 부갑상선호르몬(parathyroid hormone, PTH)에 골조직 선택성 펩타이드가 결합되어 있는 융합 펩타이드를 포함하는 약학 조성물 및 생체재료
JP7045166B2 (ja) * 2017-11-07 2022-03-31 株式会社ニッピ コラーゲン結合材、その製造方法、ドラッグデリバリーシステム、および担持体
JP2021516966A (ja) 2018-03-09 2021-07-15 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 組織への生物学的薬物の送達
US20220363778A1 (en) * 2019-08-28 2022-11-17 The Research Foundation For The State University Of New York Targeted delivery of tumor matrix modifying enzymes
WO2022050176A1 (ja) * 2020-09-02 2022-03-10 コラジェン・ファーマ株式会社 ペプチドを含む組成物及びその用途
US12403179B2 (en) 2021-02-18 2025-09-02 The Board Of Trustees Of The University Of Arkansas Release of growth factors at wound healing stages
JP2025521751A (ja) * 2022-06-27 2025-07-10 サステイン ホールディングス，エルエルシー コラーゲンペプチドベースの医薬組成物及びその使用

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8516421D0 (en) 1985-06-28 1985-07-31 Biotechnology Interface Ltd Fibronectins
DE69429337T3 (de) * 1993-04-02 2012-08-30 Anticancer Inc. Verfahren zur verabreichung von förderlichen zusammensetzungen auf die haarfollikel
JP4142743B2 (ja) 1996-07-31 2008-09-03 ザ・ジェネラル・ホスピタル・コーポレイション 副甲状腺ホルモンに関連する新規ペプチド類似体
US20100267012A1 (en) * 1997-11-04 2010-10-21 Bergeron Michel G Highly conserved genes and their use to generate probes and primers for detection of microorganisms
US6387663B1 (en) 1998-07-31 2002-05-14 University Of Southern California Targeting pharmaceutical agents to injured tissues
US7601685B2 (en) 1998-08-27 2009-10-13 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
US20020102709A1 (en) 1999-02-19 2002-08-01 Tetsuya Ishikawa Collagen-binding physiologically active polypeptide
EP1151116A1 (en) 1999-02-19 2001-11-07 Terumo Kabushiki Kaisha Collagen-binding physiologically active polypeptide
US6908994B1 (en) 1999-05-10 2005-06-21 The Texas A&M University System Collagen-binding proteins from enterococcal bacteria
US6756480B2 (en) * 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US20050124537A1 (en) 2000-04-27 2005-06-09 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US20040053368A1 (en) 2000-08-15 2004-03-18 Tetsuya Ishikawa Collagen-binding hybrid polypeptide
JP2002058485A (ja) * 2000-08-16 2002-02-26 Terumo Corp コラーゲン結合性を有する骨形成促進融合蛋白質
JP4560291B2 (ja) 2001-12-18 2010-10-13 イジュノシッヒ テクニッヒ ホッフシューラ チューリッヒ 組織操作のための成長因子改変タンパク質マトリクス
AU2003256839B2 (en) 2002-07-25 2009-10-29 The General Hospital Corporation Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion
EP1592463B1 (en) 2003-02-13 2006-08-16 SYNTHES AG Chur Injectable bone-replacement mixture
US20040220094A1 (en) 2003-05-01 2004-11-04 Skinner Keith K. Inverse agonist and agonist peptides that stimulate/inhibit hair growth
CA2542834C (en) 2003-10-21 2012-04-24 Igf Oncology, Llc Conjugates or co-administration of igf-1 receptor ligands with anti-cancer chemotherapeutic agents
WO2005046798A1 (en) 2003-11-12 2005-05-26 Nps Allelix Corp. Treatment of bone loss utilizing full length parathyroid hormone
EP1557176A1 (en) 2004-01-26 2005-07-27 Ferring B.V. Treatment of bone metastases by means of PTH receptor agonists
WO2005078085A1 (ja) * 2004-02-16 2005-08-25 Techno Network Shikoku Co., Ltd. コラーゲン様構造を有するポリペプチド
WO2005082941A1 (en) 2004-02-27 2005-09-09 The University Of Western Ontario Bone sialoprotein collagen-binding peptides
CA2559228C (en) 2004-04-21 2016-06-21 Enobia Pharma Inc. Bone delivery conjugates and method of using same to target proteins to bone
WO2006047214A2 (en) 2004-10-21 2006-05-04 Igf Oncology, Llc Toxins and radionuclides coupled to igf-1 receptor ligands for treatment of cancer
WO2006073711A2 (en) 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
WO2007073661A1 (fr) * 2005-12-26 2007-07-05 Yantai Zhenghai Bio-Technology Co., Ltd. Matieres de squelette de collagene activees et leurs facteurs speciaux de restauration active fusionnee
JP5645408B2 (ja) * 2006-11-16 2014-12-24 カイ ファーマシューティカルズ インコーポレーティッド 副甲状腺機能亢進症および高カルシウム血症性障害の治療のためのポリカチオン性カルシウムモジュレーターペプチド
EP1961765A1 (en) * 2006-12-08 2008-08-27 Zealand Pharma A/S Truncated PTH peptides with a cyclic conformation
WO2008101406A1 (en) * 2007-02-14 2008-08-28 Yolare Dermaceuticals, Llc Modified mutant collagenase and it's use in fat melting and in scar reduction
WO2008123166A1 (en) * 2007-03-20 2008-10-16 Nsk-Warner K.K. Roller-type one-way clutch
CA2930681C (en) * 2007-04-09 2019-10-15 The Board Of Trustees Of The University Of Arkansas Fusion protein of collagen-binding domain and parathyroid hormone
US8486422B2 (en) * 2007-07-26 2013-07-16 Allergan, Inc. Methods of activating clostridial toxins
US20100159564A1 (en) * 2007-11-30 2010-06-24 Dwulet Francis E Protease resistant recombinant bacterial collagenases
JP5400336B2 (ja) 2008-08-04 2014-01-29 トヨタ紡織株式会社 表皮材の成形装置
US10545149B2 (en) 2008-10-06 2020-01-28 Morehouse School Of Medicine Detection of HIV-related proteins in urine
JP2010172247A (ja) 2009-01-29 2010-08-12 Kitasato Institute 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織
US10046040B2 (en) * 2009-11-16 2018-08-14 University Of Maryland, Baltimore Multivalent live vector vaccine against Clostridium difficile-associated disease
JPWO2011142425A1 (ja) * 2010-05-12 2013-07-22 国立大学法人 香川大学 上皮層含有組織の再生材および再生評価方法
ES2385239B1 (es) * 2010-09-30 2013-06-19 Proteos Biotech S.L.U. Uso de colagenasa g recombinante, colagenasa h recombinante y pz-peptidasa recombinante para el tratamiento de enfermedades que cursan con alteraciones del colágeno.
EP2687847B1 (en) * 2011-03-16 2019-03-06 Tohoku University Probe for analyzing biological tissue and method for utilizing same
US9248164B2 (en) * 2011-05-13 2016-02-02 School Juridical Person Kitasato Institute Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone
WO2013120060A1 (en) * 2012-02-09 2013-08-15 The Board Of Trustees Of The University Of Arkansas Delivery of therapeutic agents by a collagen binding protein
US9579273B2 (en) * 2011-12-14 2017-02-28 The Kitasato Institute Delivery of therapeutic agents by a collagen binding protein
CA2861033C (en) * 2012-01-12 2017-07-25 Auxilium International Holdings, Inc. Clostridium histolyticum enzymes and methods for the use thereof
WO2013120030A1 (en) * 2012-02-08 2013-08-15 Shining Golden Yida Welding & Cutting Machinery Manufacture Ltd. Rotary vane air motor with improved vanes and other improvements
JP6403062B2 (ja) * 2012-12-21 2018-10-10 国立大学法人徳島大学 組織修復活性組成物及びその利用
RU2016110800A (ru) * 2013-09-25 2017-10-30 Пронутриа Биосайенсис, Инк. Составы и композиции для поддержания и увеличения мышечной массы, силы и результативности, и способы их производства и использования
US9539363B2 (en) * 2014-04-24 2017-01-10 Warsaw Orthopedic, Inc. Collagen matrix
WO2016060252A1 (ja) * 2014-10-16 2016-04-21 学校法人北里研究所 神経再生用移植材料、神経再生用移植材料の製造方法、及び神経再生用移植材料製造用キット
EP3112474A1 (en) * 2015-06-29 2017-01-04 Evonik Degussa GmbH Method of detecting avian necrotic enteritis
US10513696B2 (en) * 2016-05-24 2019-12-24 Hamzeh Alipour Lucilia sericata collagenase
KR102627405B1 (ko) * 2016-09-29 2024-01-18 아센디스 파마 본 디지즈 에이/에스 조절 방출 pth 화합물을 위한 투여 용법
WO2018148573A1 (en) * 2017-02-10 2018-08-16 The Board Of Trustees Of The University Of Arkansas Collagen-binding agent compositions and methods of using the same
WO2019113123A1 (en) * 2017-12-04 2019-06-13 Precithera, Inc. TGF-ß RECEPTOR FUSION PROTEINS AND OTHER TGF-ß ANTAGONISTS FOR REDUCING TGF-ß SIGNALING
EP3743081A4 (en) * 2018-01-23 2021-12-01 New York University SPECIFIC ANTIBODIES OF THE DELTA 1 CHAIN OF THE T-LYMPHOCYTE RECEPTOR
JP2021516966A (ja) * 2018-03-09 2021-07-15 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 組織への生物学的薬物の送達
US10947236B2 (en) * 2018-08-14 2021-03-16 Osteoqc Inc. Pyrrolo-dipyridine compounds

Similar Documents

Publication Publication Date Title
JP2015513312A5 (https=)
JP2018104461A5 (https=)
JP7327765B2 (ja) コラーゲン結合タンパク質による治療剤の送達
RU2014103185A (ru) Биологически активное соединение на основе лютеинизирующего гормона (lh) с пролонгированным действием
RU2012151205A (ru) Модифицированные связывающие белки, ингибирующие взаимодействие vegf-a рецептора
FI2970398T3 (fi) Rsv f -prefuusioproteiineja ja niiden käyttö
JP2015500811A5 (https=)
ME02652B (me) Stabilizovana varijanta aktivin iib receptora
JP2014526441A5 (https=)
JP2013534812A5 (https=)
RU2011110741A (ru) Основанные на notch3 человека гибридные белки в качестве ловушек-ингибиторов передачи сигнала notch3
JP2012530504A5 (https=)
RU2015136440A (ru) Композиции и способы применения для лечения метаболических расстройств
AR065289A1 (es) Antagonistas de activina - actriia y sus usos para la promocion del crecimiento oseo y el tratamiento de mieloma multiple
JP2009515529A5 (https=)
NO20071093L (no) Nye anti-IGF-IR-antistoffer og anvendelse derav
JP2010202664A5 (https=)
MXPA01007956A (es) Polipeptido antimicrobiano/neutralizador de endotoxina.
RU2018108421A (ru) Рекомбинантные белки и их применения в терапевтических целях
MX2011004031A (es) Composiciones y metodos para el tratamiento de trastornos renales.
FI3774859T3 (fi) Ihmisen neureguliini-1:n (nrg-1) rekombinanttifuusioproteiinikoostumukset ja niiden käyttömenetelmät
DK2457578T3 (en) A chimeric molecule comprising angiopoietin-1 and a coiled-coil domain for use in the treatment of erectile dysfunction of the penis
JP2017504589A5 (https=)
JP2021505624A5 (https=)
JP2009520758A5 (https=)