JP2015512255A - ざ瘡の高速診断および個人化された治療 - Google Patents
ざ瘡の高速診断および個人化された治療 Download PDFInfo
- Publication number
- JP2015512255A JP2015512255A JP2015501822A JP2015501822A JP2015512255A JP 2015512255 A JP2015512255 A JP 2015512255A JP 2015501822 A JP2015501822 A JP 2015501822A JP 2015501822 A JP2015501822 A JP 2015501822A JP 2015512255 A JP2015512255 A JP 2015512255A
- Authority
- JP
- Japan
- Prior art keywords
- seq
- acne
- strain
- strains
- phage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/00032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261612290P | 2012-03-17 | 2012-03-17 | |
| US61/612,290 | 2012-03-17 | ||
| PCT/US2013/032551 WO2013142378A1 (en) | 2012-03-17 | 2013-03-15 | Fast diagnosis and personalized treatments for acne |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019002573A Division JP2019050833A (ja) | 2012-03-17 | 2019-01-10 | ざ瘡の高速診断および個人化された治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015512255A true JP2015512255A (ja) | 2015-04-27 |
| JP2015512255A5 JP2015512255A5 (https=) | 2016-05-12 |
Family
ID=49223275
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015501822A Withdrawn JP2015512255A (ja) | 2012-03-17 | 2013-03-15 | ざ瘡の高速診断および個人化された治療 |
| JP2019002573A Pending JP2019050833A (ja) | 2012-03-17 | 2019-01-10 | ざ瘡の高速診断および個人化された治療 |
| JP2020188630A Pending JP2021013395A (ja) | 2012-03-17 | 2020-11-12 | ざ瘡の高速診断および個人化された治療 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019002573A Pending JP2019050833A (ja) | 2012-03-17 | 2019-01-10 | ざ瘡の高速診断および個人化された治療 |
| JP2020188630A Pending JP2021013395A (ja) | 2012-03-17 | 2020-11-12 | ざ瘡の高速診断および個人化された治療 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US20150086581A1 (https=) |
| EP (3) | EP2825676B1 (https=) |
| JP (3) | JP2015512255A (https=) |
| CN (2) | CN104364394B (https=) |
| AU (3) | AU2013235340B2 (https=) |
| BR (1) | BR112014023005A2 (https=) |
| CA (1) | CA2867621A1 (https=) |
| SG (1) | SG11201405783VA (https=) |
| WO (1) | WO2013142378A1 (https=) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017014256A1 (ja) * | 2015-07-21 | 2017-01-26 | TAK-Circulator株式会社 | 身体状態の評価方法、情報の提示方法、および身体状態を改善又は予防する物質のスクリーニング方法 |
| JP2017086072A (ja) * | 2015-11-04 | 2017-05-25 | 学校法人慶應義塾 | 対象物の使用者を判定する方法 |
| JP6231252B1 (ja) * | 2016-07-08 | 2017-11-15 | 花王株式会社 | 核酸試料の調製方法 |
| US9889165B2 (en) | 2016-04-21 | 2018-02-13 | Naked Biome, Inc. | Compositions and methods for treatment of skin disorders |
| WO2018084112A1 (ja) | 2016-11-01 | 2018-05-11 | 株式会社桃谷順天館 | アクネ菌株選択的抗菌剤 |
| JP2019509263A (ja) * | 2016-02-05 | 2019-04-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の健康増進用組成物及び健康増進方法 |
| JP2020517735A (ja) * | 2017-04-21 | 2020-06-18 | ピー・エイチ・アイ・セラピューティクス・インコーポレイテッド | ざ瘡を治療するためのプロピオニバクテリウムアクネス(Propionibacterium acnes)バクテリオファージを含む組成物 |
| JP2022539826A (ja) * | 2019-07-12 | 2022-09-13 | ビオメリュー | 細菌発生の疫学的識別および監視のための方法 |
Families Citing this family (123)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9457077B2 (en) | 2009-11-18 | 2016-10-04 | Katherine Rose Kovarik | Method and system for targeting the microbiome to promote health and treat allergic and inflammatory diseases |
| US9585920B2 (en) | 2011-02-04 | 2017-03-07 | Katherine Rose Kovarik | Method and system for treating cancer cachexia |
| US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
| US11273187B2 (en) | 2015-11-30 | 2022-03-15 | Joseph E. Kovarik | Method and system for reducing the likelihood of developing depression in an individual |
| US10314865B2 (en) | 2011-02-04 | 2019-06-11 | Katherine Rose Kovarik | Method and system for treating cancer and other age-related diseases by extending the healthspan of a human |
| US12279989B2 (en) | 2011-02-04 | 2025-04-22 | Seed Health, Inc. | Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity |
| US10940169B2 (en) | 2015-11-30 | 2021-03-09 | Joseph E. Kovarik | Method for reducing the likelihood of developing cancer in an individual human being |
| US11357722B2 (en) | 2011-02-04 | 2022-06-14 | Seed Health, Inc. | Method and system for preventing sore throat in humans |
| US12257272B2 (en) | 2015-12-24 | 2025-03-25 | Seed Health, Inc. | Method and system for reducing the likelihood of developing depression in an individual |
| US12533312B2 (en) | 2011-02-04 | 2026-01-27 | Seed Health, Inc. | Method and system for preventing sore throat in humans |
| US11419903B2 (en) | 2015-11-30 | 2022-08-23 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
| US9987224B2 (en) | 2011-02-04 | 2018-06-05 | Joseph E. Kovarik | Method and system for preventing migraine headaches, cluster headaches and dizziness |
| US10835560B2 (en) | 2013-12-20 | 2020-11-17 | Joseph E. Kovarik | Reducing the likelihood of skin cancer in an individual human being |
| US11523934B2 (en) | 2011-02-04 | 2022-12-13 | Seed Health, Inc. | Method and system to facilitate the growth of desired bacteria in a human's mouth |
| US11951139B2 (en) | 2015-11-30 | 2024-04-09 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
| US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
| US10245288B2 (en) | 2011-02-04 | 2019-04-02 | Joseph E. Kovarik | Method and system for reducing the likelihood of developing NASH in an individual diagnosed with non-alcoholic fatty liver disease |
| US10086018B2 (en) | 2011-02-04 | 2018-10-02 | Joseph E. Kovarik | Method and system for reducing the likelihood of colorectal cancer in a human being |
| US10842834B2 (en) | 2016-01-06 | 2020-11-24 | Joseph E. Kovarik | Method and system for reducing the likelihood of developing liver cancer in an individual diagnosed with non-alcoholic fatty liver disease |
| US11191665B2 (en) | 2011-02-04 | 2021-12-07 | Joseph E. Kovarik | Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being |
| US9730967B2 (en) | 2011-02-04 | 2017-08-15 | Katherine Rose Kovarik | Method and system for treating cancer cachexia |
| US10085938B2 (en) | 2011-02-04 | 2018-10-02 | Joseph E. Kovarik | Method and system for preventing sore throat in humans |
| US10687975B2 (en) | 2011-02-04 | 2020-06-23 | Joseph E. Kovarik | Method and system to facilitate the growth of desired bacteria in a human's mouth |
| US10512661B2 (en) | 2011-02-04 | 2019-12-24 | Joseph E. Kovarik | Method and system for reducing the likelihood of developing liver cancer in an individual diagnosed with non-alcoholic fatty liver disease |
| US10548761B2 (en) | 2011-02-04 | 2020-02-04 | Joseph E. Kovarik | Method and system for reducing the likelihood of colorectal cancer in a human being |
| US10111913B2 (en) | 2011-02-04 | 2018-10-30 | Joseph E. Kovarik | Method of reducing the likelihood of skin cancer in an individual human being |
| US11844720B2 (en) | 2011-02-04 | 2023-12-19 | Seed Health, Inc. | Method and system to reduce the likelihood of dental caries and halitosis |
| US10583033B2 (en) | 2011-02-04 | 2020-03-10 | Katherine Rose Kovarik | Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being |
| US10010568B2 (en) | 2011-02-04 | 2018-07-03 | Katherine Rose Kovarik | Method and system for reducing the likelihood of a spirochetes infection in a human being |
| US10323236B2 (en) | 2011-07-22 | 2019-06-18 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| EP2825676B1 (en) | 2012-03-17 | 2017-12-20 | The Regents of The University of California | Fast diagnosis and personalized treatments for acne |
| US11072832B2 (en) | 2013-06-18 | 2021-07-27 | Prodermiq, Inc. | Customized skin care products and personal care products based on the analysis of skin flora |
| JP6637885B2 (ja) | 2013-07-21 | 2020-01-29 | ペンデュラム セラピューティクス, インコーポレイテッド | マイクロバイオームの特性解明、モニタリング、および処置のための方法およびシステム |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| CN106459995B (zh) | 2013-11-07 | 2020-02-21 | 爱迪塔斯医药有限公司 | 使用统治型gRNA的CRISPR相关方法和组合物 |
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
| US12329783B2 (en) | 2013-12-20 | 2025-06-17 | Seed Health, Inc. | Method and system to improve the health of a person's skin microbiome |
| US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
| US11213552B2 (en) | 2015-11-30 | 2022-01-04 | Joseph E. Kovarik | Method for treating an individual suffering from a chronic infectious disease and cancer |
| US12246043B2 (en) | 2013-12-20 | 2025-03-11 | Seed Health, Inc. | Topical application to treat acne vulgaris |
| US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
| US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
| US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
| US11826388B2 (en) | 2013-12-20 | 2023-11-28 | Seed Health, Inc. | Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation |
| US12318377B2 (en) | 2013-12-20 | 2025-06-03 | Seed Health, Inc. | Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being |
| US11529379B2 (en) | 2013-12-20 | 2022-12-20 | Seed Health, Inc. | Method and system for reducing the likelihood of developing colorectal cancer in an individual human being |
| US11672835B2 (en) | 2013-12-20 | 2023-06-13 | Seed Health, Inc. | Method for treating individuals having cancer and who are receiving cancer immunotherapy |
| US11642382B2 (en) | 2013-12-20 | 2023-05-09 | Seed Health, Inc. | Method for treating an individual suffering from bladder cancer |
| US11026982B2 (en) | 2015-11-30 | 2021-06-08 | Joseph E. Kovarik | Method for reducing the likelihood of developing bladder or colorectal cancer in an individual human being |
| US11833177B2 (en) | 2013-12-20 | 2023-12-05 | Seed Health, Inc. | Probiotic to enhance an individual's skin microbiome |
| US11839632B2 (en) | 2013-12-20 | 2023-12-12 | Seed Health, Inc. | Topical application of CRISPR-modified bacteria to treat acne vulgaris |
| EP4299122A3 (en) * | 2014-05-07 | 2024-03-27 | The Regents of The University of California | Compositions and methods for treating skin and mucous membrane diseases |
| SI3158054T1 (sl) | 2014-06-17 | 2025-06-30 | Crown Laboratories, Inc. | Genetsko modificirane bakterije in postopki za genetsko modifikacijo bakterij |
| US10077453B2 (en) | 2014-07-30 | 2018-09-18 | President And Fellows Of Harvard College | CAS9 proteins including ligand-dependent inteins |
| SG11201701245QA (en) | 2014-08-27 | 2017-03-30 | Caribou Biosciences Inc | Methods for increasing cas9-mediated engineering efficiency |
| US10410749B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions |
| WO2016065075A1 (en) | 2014-10-21 | 2016-04-28 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics |
| US10169541B2 (en) | 2014-10-21 | 2019-01-01 | uBiome, Inc. | Method and systems for characterizing skin related conditions |
| AU2016250100A1 (en) * | 2015-04-13 | 2017-11-09 | Psomagen, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions |
| EP3285872A4 (en) * | 2015-04-20 | 2019-02-20 | S-Biomedic NV | METHOD AND COMPOSITIONS FOR CHANGING THE COMPOSITION OF SKIN MICROBIOMA WITH COMPLEX MIXTURES OF BACTERIAL BARS |
| CN108271392B (zh) * | 2015-08-06 | 2023-01-10 | 阿瑞斯遗传股份有限公司 | 在微生物中利用基因组中结构变化对抗微生物药物的基因抗性预测 |
| US11773455B2 (en) | 2015-09-09 | 2023-10-03 | Psomagen, Inc. | Method and system for microbiome-derived diagnostics and therapeutics infectious disease and other health conditions associated with antibiotic usage |
| EP3346910A4 (en) * | 2015-09-09 | 2019-05-15 | Ubiome Inc. | METHOD AND COMPOSITIONS FOR MICROBIOMA DIAGNOSIS AND THERAPEUTIC AGAINST ECCEM |
| WO2017044885A1 (en) * | 2015-09-09 | 2017-03-16 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with cerebro-craniofacial health |
| US10679725B2 (en) | 2015-09-17 | 2020-06-09 | Prodermiq, Inc. | Predicting skin age based on the analysis of skin flora and lifestyle data |
| IL310721B2 (en) | 2015-10-23 | 2025-11-01 | Harvard College | Nucleobase editors and uses thereof |
| GB2544481B (en) * | 2015-11-16 | 2019-12-11 | Century International Enterprises Ltd | A wearable article and a method for producing a wearable article |
| US10568916B2 (en) | 2015-11-30 | 2020-02-25 | Joseph E. Kovarik | Method and system for protecting honey bees, bats and butterflies from neonicotinoid pesticides |
| US10086024B2 (en) | 2015-11-30 | 2018-10-02 | Joseph E. Kovarik | Method and system for protecting honey bees, bats and butterflies from neonicotinoid pesticides |
| US10933128B2 (en) | 2015-11-30 | 2021-03-02 | Joseph E. Kovarik | Method and system for protecting honey bees from pesticides |
| US12239706B2 (en) | 2015-11-30 | 2025-03-04 | Seed Health, Inc. | Method and system for protecting monarch butterflies from pesticides |
| US10675347B2 (en) | 2015-11-30 | 2020-06-09 | Joseph E. Kovarik | Method and system for protecting honey bees from fipronil pesticides |
| US11529412B2 (en) | 2015-11-30 | 2022-12-20 | Seed Health, Inc. | Method and system for protecting honey bees from pesticides |
| WO2017147507A1 (en) | 2016-02-24 | 2017-08-31 | Xycrobe Therapeutics, Inc. | Skin probiotic formulation |
| WO2017185018A1 (en) * | 2016-04-21 | 2017-10-26 | Naked Biome, Inc. | Synthetic bacteria and methods of use |
| CA3022294A1 (en) * | 2016-04-25 | 2017-11-02 | uBiome, Inc. | Method and system for characterizing skin-related conditions |
| EP3243907A1 (en) * | 2016-05-13 | 2017-11-15 | Curetis GmbH | Stable pan-genomes and their use |
| CN109689861A (zh) * | 2016-05-15 | 2019-04-26 | 加州大学评议会 | 用于治疗痤疮的组合物和方法 |
| CN106167820A (zh) * | 2016-05-19 | 2016-11-30 | 胤安国际(辽宁)基因科技股份有限公司 | 鉴定或辅助鉴定痤疮丙酸杆菌的专用引物及其应用 |
| CN110214183A (zh) | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | 腺苷核碱基编辑器及其用途 |
| WO2018031683A1 (en) | 2016-08-09 | 2018-02-15 | President And Fellows Of Harvard College | Programmable cas9-recombinase fusion proteins and uses thereof |
| US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| KR102622411B1 (ko) | 2016-10-14 | 2024-01-10 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵염기 에디터의 aav 전달 |
| US11541081B2 (en) | 2016-10-19 | 2023-01-03 | S-Biomedic Nv | Methods and compositions for changing the composition of the skin microbiome using complex mixtures of bacterial strains |
| EP3538119A4 (en) * | 2016-11-08 | 2020-07-01 | The Regents of The University of California | COMPOSITIONS AND METHODS FOR TREATING SKIN DISEASES AND MAINTAINING HEALTHY SKIN |
| WO2018119359A1 (en) | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| US11915795B2 (en) * | 2016-12-23 | 2024-02-27 | The Regents Of The University Of California | Method and device for digital high resolution melt |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| US12390514B2 (en) | 2017-03-09 | 2025-08-19 | President And Fellows Of Harvard College | Cancer vaccine |
| CA3055930A1 (en) | 2017-03-10 | 2018-09-13 | Prodermiq, Inc. | Customized skin care products and personal care products based on the analysis of skin flora |
| US11542496B2 (en) | 2017-03-10 | 2023-01-03 | President And Fellows Of Harvard College | Cytosine to guanine base editor |
| KR20240116572A (ko) | 2017-03-23 | 2024-07-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
| US11560566B2 (en) | 2017-05-12 | 2023-01-24 | President And Fellows Of Harvard College | Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation |
| CN111801345A (zh) | 2017-07-28 | 2020-10-20 | 哈佛大学的校长及成员们 | 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物 |
| EP3676376B1 (en) | 2017-08-30 | 2025-01-15 | President and Fellows of Harvard College | High efficiency base editors comprising gam |
| KR20250107288A (ko) | 2017-10-16 | 2025-07-11 | 더 브로드 인스티튜트, 인코퍼레이티드 | 아데노신 염기 편집제의 용도 |
| WO2019079612A1 (en) * | 2017-10-20 | 2019-04-25 | Naked Biome, Inc. | SYSTEMS AND METHODS OF BACTERIAL DETECTION AND TREATMENT |
| US20210177920A1 (en) * | 2017-12-05 | 2021-06-17 | Biomx Ltd. | Bacteriophage treatment for acne and biofilms |
| US12406749B2 (en) | 2017-12-15 | 2025-09-02 | The Broad Institute, Inc. | Systems and methods for predicting repair outcomes in genetic engineering |
| US12157760B2 (en) | 2018-05-23 | 2024-12-03 | The Broad Institute, Inc. | Base editors and uses thereof |
| US12522807B2 (en) | 2018-07-09 | 2026-01-13 | The Broad Institute, Inc. | RNA programmable epigenetic RNA modifiers and uses thereof |
| WO2020055547A2 (en) | 2018-08-18 | 2020-03-19 | Seed Health, Inc. | Methods and compositions for honey bee health |
| WO2020092453A1 (en) | 2018-10-29 | 2020-05-07 | The Broad Institute, Inc. | Nucleobase editors comprising geocas9 and uses thereof |
| US20220002782A1 (en) * | 2018-11-01 | 2022-01-06 | Kao Corporation | Method for preparing nucleic acid derived from skin cell of subject |
| CA3118524A1 (en) * | 2018-11-16 | 2020-05-22 | S-biomedic N.v. | Compositions for treating oxidative stress-associated skin diseases and skin ageing and diagnosis of oxidative stress-associated skin diseases |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| WO2020191233A1 (en) | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
| US12473543B2 (en) | 2019-04-17 | 2025-11-18 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| KR102746770B1 (ko) * | 2019-07-10 | 2024-12-30 | 루오웨이 지앙 | 피부 분석을 위한 이미지들을 프로세싱하고 피부 분석을 시각화하기 위한 시스템들 및 방법들 |
| EP3999624B1 (en) | 2019-07-16 | 2026-03-25 | Meliolabs Inc. | Methods and devices for single-cell based digital high resolution melt |
| EP4003381A4 (en) * | 2019-07-22 | 2024-02-28 | The Regents of the University of California | COMPOSITIONS AND METHODS FOR TREATING SKIN INFECTIONS AND OTHER DISEASES |
| US12435330B2 (en) | 2019-10-10 | 2025-10-07 | The Broad Institute, Inc. | Methods and compositions for prime editing RNA |
| US12516309B2 (en) | 2019-10-31 | 2026-01-06 | University Of Maryland, College Park | Method of treating infections by bacteriolytic enzymes and manufacture thereof |
| IL297761A (en) | 2020-05-08 | 2022-12-01 | Broad Inst Inc | Methods and compositions for simultaneously editing two helices of a designated double-helix nucleotide sequence |
| US12102710B2 (en) | 2020-06-23 | 2024-10-01 | Crown Laboratories, Inc. | Probiotic skin formulations |
| EP4308735A4 (en) * | 2021-03-19 | 2025-02-19 | Parallel Health, Inc. | MICROBIOME IDENTIFICATION AND BACTERIOPHAGE FORMULATIONS |
| CN113066533B (zh) * | 2021-04-02 | 2023-04-04 | 欧蒙医学诊断(中国)有限公司 | 一种mNGS病原体数据分析方法 |
| US12502424B2 (en) | 2023-05-05 | 2025-12-23 | Sanofi Pasteur Inc. | Compositions for use in treatment of acne |
| CN118737269B (zh) * | 2024-08-30 | 2024-11-19 | 墨卓生物科技(浙江)有限公司 | 在单细胞微生物基因组测序结果中区分菌株的方法 |
| US20260092332A1 (en) * | 2024-10-01 | 2026-04-02 | L'oreal | Skin microbiome-based methods for acne assessment and treatment |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003033515A1 (en) * | 2001-10-15 | 2003-04-24 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of acne vulgaris |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU670777B2 (en) | 1992-04-16 | 1996-08-01 | Ortho Pharmaceutical Corporation | Aqueous gel vehicles for retinoids |
| US5836999A (en) | 1995-09-28 | 1998-11-17 | Esc Medical Systems Ltd. | Method and apparatus for treating psoriasis using pulsed electromagnetic radiation |
| CA2251724A1 (en) | 1996-04-15 | 1997-10-23 | Paul Averback | Compositions containing bacteriophages and methods of using bacteriophages to treat infections |
| JPH11171783A (ja) | 1997-08-15 | 1999-06-29 | Vetoquinol Sa | 所定の動物に関して細胞性免疫と体重増加を生じる濃度でのバクテリアの経口投与 |
| AU763105B2 (en) * | 1998-05-22 | 2003-07-10 | Inzinta Trading Co. Ltd | Demonstrating resistance to antibiotics in microorganisms |
| US6726913B1 (en) | 1999-10-15 | 2004-04-27 | The Van Kampen Group, Inc. | Treatment of dermal tumors, warts, and viral infections of the respiratory tract in humans using heat-killed P. acnes |
| JP2004520803A (ja) | 2000-04-21 | 2004-07-15 | コリクサ コーポレイション | 尋常性挫瘡の治療および診断のための組成物および方法 |
| US20030092163A1 (en) * | 2001-07-26 | 2003-05-15 | Collins John Kevin | Probiotic bifidobacterium strains |
| US20040157837A1 (en) | 2002-11-07 | 2004-08-12 | Serbedzija George N. | Combinations for the treatment of fungal infections |
| NZ539076A (en) * | 2005-03-29 | 2008-05-30 | Blis Technologies Ltd | Skin treatment compositions |
| JP5127708B2 (ja) * | 2005-07-12 | 2013-01-23 | マイクレオス べスローテン フェンノートシャップ | バクテリオファージ及びその使用 |
| US20070269813A1 (en) | 2005-11-03 | 2007-11-22 | Dewhirst Floyd E | Methods and arrays for identifying human microflora |
| JP5201818B2 (ja) * | 2006-11-10 | 2013-06-05 | キヤノン株式会社 | プローブセット、プローブ固定担体及び遺伝子検査方法 |
| EP2184997A4 (en) | 2007-07-31 | 2010-11-03 | Univ New York | DIAGNOSIS AND TREATMENT METHODS FOR THE CHARACTERIZATION OF BACTERIAL MICROORGANISMS IN SKIN DISEASES |
| EP2082736A1 (fr) * | 2008-01-23 | 2009-07-29 | Jean Hilaire Saurat | Composition pharmaceutique à usage topique |
| WO2009105592A2 (en) * | 2008-02-19 | 2009-08-27 | Hogan James J | Compositions and methods for detection of propionibacterium acnes nucleic acid |
| US9340769B2 (en) | 2008-12-05 | 2016-05-17 | The Regents Of The University Of California | Methods and compositions for treating P. acnes |
| US9457077B2 (en) * | 2009-11-18 | 2016-10-04 | Katherine Rose Kovarik | Method and system for targeting the microbiome to promote health and treat allergic and inflammatory diseases |
| AU2011259204B2 (en) * | 2010-05-27 | 2015-05-21 | Kenichiro Hasumi | Antigen peptide and use thereof |
| EP2825676B1 (en) * | 2012-03-17 | 2017-12-20 | The Regents of The University of California | Fast diagnosis and personalized treatments for acne |
| EP2664919A1 (fr) * | 2012-05-15 | 2013-11-20 | Jean Hilaire Saurat | Une méthode pour identifier les ligands du récepteur AhR possédant une activité sebosuppressive thérapeutique |
| JP2015524653A (ja) * | 2012-07-13 | 2015-08-27 | ロレアル | 対象における薄皮状態のインビトロ診断方法及び関連用途 |
| MX2015001751A (es) | 2012-08-07 | 2015-11-13 | Topgenix Inc | Composicion topica comprendiendo bacterias transformadas que expresan un compuesto de interes. |
| US8906668B2 (en) * | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
| JP2016509003A (ja) * | 2013-02-04 | 2016-03-24 | セレス セラピューティクス インコーポレイテッド | 組成物および方法 |
| CN105979952B (zh) * | 2013-11-25 | 2022-04-08 | 赛里斯治疗公司 | 协同细菌组合物以及其制造方法和用途 |
| US9737592B1 (en) * | 2014-02-14 | 2017-08-22 | David Gordon Bermudes | Topical and orally administered protease inhibitors and bacterial vectors for the treatment of disorders and methods of treatment |
| EP4299122A3 (en) | 2014-05-07 | 2024-03-27 | The Regents of The University of California | Compositions and methods for treating skin and mucous membrane diseases |
| SI3158054T1 (sl) * | 2014-06-17 | 2025-06-30 | Crown Laboratories, Inc. | Genetsko modificirane bakterije in postopki za genetsko modifikacijo bakterij |
| US20190008930A1 (en) * | 2015-07-31 | 2019-01-10 | The Regents Of The University Of California | Mycobacterium lysterase: a novel treatment for acne |
| CN109562048A (zh) * | 2016-02-05 | 2019-04-02 | 加州大学评议会 | 用于促进皮肤健康的组合物和方法 |
| US9889165B2 (en) * | 2016-04-21 | 2018-02-13 | Naked Biome, Inc. | Compositions and methods for treatment of skin disorders |
| CN109689861A (zh) * | 2016-05-15 | 2019-04-26 | 加州大学评议会 | 用于治疗痤疮的组合物和方法 |
| US11541081B2 (en) * | 2016-10-19 | 2023-01-03 | S-Biomedic Nv | Methods and compositions for changing the composition of the skin microbiome using complex mixtures of bacterial strains |
| US20210177920A1 (en) * | 2017-12-05 | 2021-06-17 | Biomx Ltd. | Bacteriophage treatment for acne and biofilms |
| US12102710B2 (en) * | 2020-06-23 | 2024-10-01 | Crown Laboratories, Inc. | Probiotic skin formulations |
-
2013
- 2013-03-15 EP EP13764219.5A patent/EP2825676B1/en not_active Not-in-force
- 2013-03-15 BR BR112014023005A patent/BR112014023005A2/pt not_active Application Discontinuation
- 2013-03-15 CN CN201380025853.4A patent/CN104364394B/zh not_active Expired - Fee Related
- 2013-03-15 EP EP19218444.8A patent/EP3692999A1/en not_active Withdrawn
- 2013-03-15 CA CA2867621A patent/CA2867621A1/en not_active Abandoned
- 2013-03-15 US US14/385,576 patent/US20150086581A1/en not_active Abandoned
- 2013-03-15 AU AU2013235340A patent/AU2013235340B2/en not_active Ceased
- 2013-03-15 CN CN201910052894.1A patent/CN110055320A/zh active Pending
- 2013-03-15 WO PCT/US2013/032551 patent/WO2013142378A1/en not_active Ceased
- 2013-03-15 JP JP2015501822A patent/JP2015512255A/ja not_active Withdrawn
- 2013-03-15 EP EP17002012.7A patent/EP3360560A1/en not_active Withdrawn
- 2013-03-15 SG SG11201405783VA patent/SG11201405783VA/en unknown
-
2016
- 2016-09-06 US US15/257,423 patent/US10364473B2/en active Active
-
2019
- 2019-01-10 JP JP2019002573A patent/JP2019050833A/ja active Pending
- 2019-04-22 US US16/390,575 patent/US20190316183A1/en not_active Abandoned
- 2019-08-22 AU AU2019219817A patent/AU2019219817A1/en not_active Abandoned
-
2020
- 2020-09-02 AU AU2020227049A patent/AU2020227049A1/en not_active Abandoned
- 2020-09-25 US US17/033,034 patent/US11692229B2/en active Active
- 2020-11-12 JP JP2020188630A patent/JP2021013395A/ja active Pending
-
2023
- 2023-06-30 US US18/217,206 patent/US20240117446A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003033515A1 (en) * | 2001-10-15 | 2003-04-24 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of acne vulgaris |
Non-Patent Citations (2)
| Title |
|---|
| GENBANK PROPIONIBACTERIUM ACNES KPA171202, COMPLETE GENOME, vol. ACCESSION No.AE017283, 21-NOV-2011, JPN6017047020, pages 2017 - 11, ISSN: 0003876036 * |
| J INVEST DERMATOL. EPUB 2013 JAN 21, VOL.133, NO.9, P.2152-2160, JPN6017000570, ISSN: 0003876035 * |
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017029133A (ja) * | 2015-07-21 | 2017-02-09 | TAK−Circulator株式会社 | 身体状態の評価方法、情報の提示方法、および身体状態を改善又は予防する物質のスクリーニング方法 |
| JP2017029174A (ja) * | 2015-07-21 | 2017-02-09 | TAK−Circulator株式会社 | 身体状態の評価方法、情報の提示方法、および身体状態を改善又は予防する物質のスクリーニング方法 |
| US11802310B2 (en) | 2015-07-21 | 2023-10-31 | Myskin Corporation | Method for evaluating physical conditions, method for presenting information, and method for screening for substance capable of improving or preventing physical conditions |
| WO2017014256A1 (ja) * | 2015-07-21 | 2017-01-26 | TAK-Circulator株式会社 | 身体状態の評価方法、情報の提示方法、および身体状態を改善又は予防する物質のスクリーニング方法 |
| JP2017086072A (ja) * | 2015-11-04 | 2017-05-25 | 学校法人慶應義塾 | 対象物の使用者を判定する方法 |
| JP2019509263A (ja) * | 2016-02-05 | 2019-04-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の健康増進用組成物及び健康増進方法 |
| US11207357B2 (en) | 2016-04-21 | 2021-12-28 | Symbiome, Inc. | Compositions and methods for treatment of skin disorders |
| US9889165B2 (en) | 2016-04-21 | 2018-02-13 | Naked Biome, Inc. | Compositions and methods for treatment of skin disorders |
| US10293007B2 (en) | 2016-04-21 | 2019-05-21 | Naked Biome, Inc. | Compositions and methods for treatment of skin disorders |
| JP2018000206A (ja) * | 2016-07-08 | 2018-01-11 | 花王株式会社 | 核酸試料の調製方法 |
| WO2018008319A1 (ja) * | 2016-07-08 | 2018-01-11 | 花王株式会社 | 核酸試料の調製方法 |
| JP6231252B1 (ja) * | 2016-07-08 | 2017-11-15 | 花王株式会社 | 核酸試料の調製方法 |
| US11913061B2 (en) | 2016-07-08 | 2024-02-27 | Kao Corporation | Method for preparing nucleic acid sample |
| WO2018084112A1 (ja) | 2016-11-01 | 2018-05-11 | 株式会社桃谷順天館 | アクネ菌株選択的抗菌剤 |
| JP2020517735A (ja) * | 2017-04-21 | 2020-06-18 | ピー・エイチ・アイ・セラピューティクス・インコーポレイテッド | ざ瘡を治療するためのプロピオニバクテリウムアクネス(Propionibacterium acnes)バクテリオファージを含む組成物 |
| JP2024099592A (ja) * | 2017-04-21 | 2024-07-25 | ピー・エイチ・アイ・セラピューティクス・インコーポレイテッド | ざ瘡を治療するためのプロピオニバクテリウムアクネス(Propionibacterium acnes)バクテリオファージを含む組成物 |
| JP7595459B2 (ja) | 2017-04-21 | 2024-12-06 | ピー・エイチ・アイ・セラピューティクス・インコーポレイテッド | ざ瘡を治療するためのプロピオニバクテリウムアクネス(Propionibacterium acnes)バクテリオファージを含む組成物 |
| JP7801389B2 (ja) | 2017-04-21 | 2026-01-16 | ピー・エイチ・アイ・セラピューティクス・インコーポレイテッド | ざ瘡を治療するためのプロピオニバクテリウムアクネス(Propionibacterium acnes)バクテリオファージを含む組成物 |
| JP2022539826A (ja) * | 2019-07-12 | 2022-09-13 | ビオメリュー | 細菌発生の疫学的識別および監視のための方法 |
| JP7644082B2 (ja) | 2019-07-12 | 2025-03-11 | ビオメリュー | 細菌発生の疫学的識別および監視のための方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021013395A (ja) | 2021-02-12 |
| US20150086581A1 (en) | 2015-03-26 |
| CN110055320A (zh) | 2019-07-26 |
| WO2013142378A1 (en) | 2013-09-26 |
| US20240117446A1 (en) | 2024-04-11 |
| AU2013235340A1 (en) | 2014-10-16 |
| AU2019219817A1 (en) | 2019-09-12 |
| CN104364394B (zh) | 2019-02-22 |
| AU2020227049A1 (en) | 2020-09-17 |
| EP2825676A4 (en) | 2015-09-30 |
| US20210123092A1 (en) | 2021-04-29 |
| EP3692999A1 (en) | 2020-08-12 |
| US20170058328A1 (en) | 2017-03-02 |
| SG11201405783VA (en) | 2014-10-30 |
| US20190316183A1 (en) | 2019-10-17 |
| CA2867621A1 (en) | 2013-09-26 |
| JP2019050833A (ja) | 2019-04-04 |
| EP3360560A1 (en) | 2018-08-15 |
| AU2013235340B2 (en) | 2019-05-23 |
| EP2825676A1 (en) | 2015-01-21 |
| WO2013142378A9 (en) | 2014-01-23 |
| US11692229B2 (en) | 2023-07-04 |
| EP2825676B1 (en) | 2017-12-20 |
| HK1207402A1 (en) | 2016-01-29 |
| US10364473B2 (en) | 2019-07-30 |
| BR112014023005A2 (pt) | 2017-07-18 |
| CN104364394A (zh) | 2015-02-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11692229B2 (en) | Fast diagnosis and personalized treatments for acne | |
| Springman et al. | Pilus distribution among lineages of group b streptococcus: an evolutionary and clinical perspective | |
| Fittipaldi et al. | Full-genome dissection of an epidemic of severe invasive disease caused by a hypervirulent, recently emerged clone of group A Streptococcus | |
| Novais et al. | Co-diversification of Enterococcus faecium core genomes and PBP5: evidences of pbp5 horizontal transfer | |
| Schindler et al. | Group B streptococcus virulence factors associated with different clinical syndromes: Asymptomatic carriage in pregnant women and early-onset disease in the newborn | |
| Wu et al. | Competitive dominance within biofilm consortia regulates the relative distribution of pneumococcal nasopharyngeal density | |
| Ntozini et al. | Molecular epidemiology of invasive group B Streptococcus in South Africa, 2019–2020 | |
| Zhang et al. | Molecular signatures identify a candidate target of balancing selection in an arcD-like gene of Staphylococcus epidermidis | |
| HK40011589A (en) | Fast diagnosis and personalized treatments for acne | |
| Speck et al. | Characterization of Streptococcus equi subsp. ruminatorum isolated from spotted hyenas (Crocuta crocuta) and plains zebras (Equus burchelli), and identification of a M-like protein (SrM) encoding gene | |
| HK1207402B (zh) | 痤疮的快速诊断和个体化治疗 | |
| Kitano et al. | First human case of infected lymphocele with bloodstream infection caused by Staphylococcus coagulans transmitted from a pet dog: a case report | |
| Khan | Detailed genomic and antimicrobial resistance comparison of UK Streptococcus agalactiae isolates from adults to those of diverse global origins | |
| Piña-Iturbe et al. | Subinhibitory antibiotic concentrations promote the excision of a genomic island carried by the globally spread carbapenem-resistant Klebsiella pneumoniae sequence type 258 | |
| Conde-Pérez et al. | Evidence for translocation of oral Parvimonas micra from the subgingival sulcus of the human oral cavity to the colorectal adenocarcinoma | |
| Zhendong et al. | Isolation and identification of two highly virulent Glaesserella parasuis serovar 7 strains in China | |
| Ene | Exploring the Role of Lactobacillus jensenii and Lactobacillus mulieris in the Urogenital Tract | |
| Abdullah | Nurul Diana Dzaraly1, Mohd Nasir Mohd Desa1Ε, AbdulRahman Muthanna1, Siti Norbaya Masri2, Niazlin Mohd Taib2, Zarizal Suhaili1, 3, Nurshahira Sulaiman1, Nurul Hana Zainal Baharin1, Cheah Yun Shuan1, Zarina Ariffin1, Nor Iza A. Rahman4, Farahiyah Mohd Rani4, Navindra Kumari Palanisamy5, Tuan Suhaila Tuan Soh6 & | |
| Graham | Antibacterial activities of Propionibacterium acnes bacteriophages against a diverse collection of P. acnes clinical isolates: prospects for novel alternative therapies for acne vulgaris | |
| Willner | Viral metagenomics in host-associated systems | |
| Novais et al. | Peixe Land Coque TM (2016) Co-diversification of Enterococcus faecium Core Genomes and PBP5: Evidences of pbp5 Horizontal Transfer | |
| Proud | Examining the Role of Transformation in the Acquisition of Resistance and Rescue of Genomes from Oxidative Stress | |
| Gaiarsa | EVOLUTION, COMPARATIVE GENOMICS AND GENOMIC EPIDEMIOLOGY OF BACTERIA OF PUBLIC HEALTH IMPORTANCE | |
| Nagy | ESGARAB | |
| McAdam | Population analysis of bacterial pathogens on distinct temporal and spatial scales |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160314 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20160314 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20170117 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20170404 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170714 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20171206 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20180223 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20180502 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180606 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20180910 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190110 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20190121 |
|
| A761 | Written withdrawal of application |
Free format text: JAPANESE INTERMEDIATE CODE: A761 Effective date: 20190222 |