JP2015511948A5 - - Google Patents
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- JP2015511948A5 JP2015511948A5 JP2014557782A JP2014557782A JP2015511948A5 JP 2015511948 A5 JP2015511948 A5 JP 2015511948A5 JP 2014557782 A JP2014557782 A JP 2014557782A JP 2014557782 A JP2014557782 A JP 2014557782A JP 2015511948 A5 JP2015511948 A5 JP 2015511948A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- target
- composition
- vector
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 239000013598 vector Substances 0.000 claims 9
- 102000004473 OX40 Ligand Human genes 0.000 claims 7
- 108010042215 OX40 Ligand Proteins 0.000 claims 7
- 206010037742 Rabies Diseases 0.000 claims 7
- 241000283690 Bos taurus Species 0.000 claims 4
- 241000282326 Felis catus Species 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 4
- 241001494479 Pecora Species 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 241000120516 African horse sickness virus Species 0.000 claims 2
- 241000713800 Feline immunodeficiency virus Species 0.000 claims 2
- 241000711475 Feline infectious peritonitis virus Species 0.000 claims 2
- 241000704611 Fig cryptic virus Species 0.000 claims 2
- 241000710198 Foot-and-mouth disease virus Species 0.000 claims 2
- 241001533430 Leishmaniavirus Species 0.000 claims 2
- 241000526636 Nipah henipavirus Species 0.000 claims 2
- 241001673669 Porcine circovirus 2 Species 0.000 claims 2
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 claims 2
- 241000711975 Vesicular stomatitis virus Species 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 241000710886 West Nile virus Species 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 206010022000 influenza Diseases 0.000 claims 2
- 208000032839 leukemia Diseases 0.000 claims 2
- 241000894007 species Species 0.000 claims 2
- 241000893570 Hendra henipavirus Species 0.000 claims 1
- 241000288906 Primates Species 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261598610P | 2012-02-14 | 2012-02-14 | |
| US61/598,610 | 2012-02-14 | ||
| PCT/US2013/026206 WO2013123242A1 (en) | 2012-02-14 | 2013-02-14 | Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015511948A JP2015511948A (ja) | 2015-04-23 |
| JP2015511948A5 true JP2015511948A5 (https=) | 2016-03-03 |
| JP6260972B2 JP6260972B2 (ja) | 2018-01-17 |
Family
ID=47757705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014557782A Expired - Fee Related JP6260972B2 (ja) | 2012-02-14 | 2013-02-14 | 狂犬病タンパク質及びｏｘ４０タンパク質の両方を発現する組換えポックスウイルスベクター並びに前記ベクターから製造されるワクチン |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9567606B2 (https=) |
| EP (2) | EP3466443B1 (https=) |
| JP (1) | JP6260972B2 (https=) |
| CN (1) | CN104203271B (https=) |
| AU (1) | AU2013221502C1 (https=) |
| BR (1) | BR112014020019A8 (https=) |
| CA (1) | CA2864119C (https=) |
| EA (1) | EA032389B1 (https=) |
| ES (2) | ES2866108T3 (https=) |
| MX (1) | MX360415B (https=) |
| NZ (2) | NZ628270A (https=) |
| WO (1) | WO2013123242A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009111738A2 (en) | 2008-03-06 | 2009-09-11 | Mayo Foundation For Medical Education And Research | Single cycle replicating adenovirus vectors |
| EP3466443B1 (en) | 2012-02-14 | 2020-12-16 | Boehringer Ingelheim Animal Health USA Inc. | Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom |
| RU2718988C2 (ru) | 2013-02-22 | 2020-04-15 | Куревак Аг | Комбинация противораковой рнк-вакцины и ингибитора пути pd-1 и ее применение |
| US10196435B2 (en) * | 2013-11-18 | 2019-02-05 | University Of Southern California | OX40L fusion protein for the immunotherapy of tumors of veterinary animals |
| ES2729838T3 (es) * | 2013-12-20 | 2019-11-06 | Boehringer Ingelheim Vetmedica Gmbh | Variante del virus del PRRS, clon de ADNc del virus del PRRS europeo y usos del mismo |
| CN103877570B (zh) * | 2014-02-19 | 2016-01-20 | 北京中联康生物科技有限公司 | 狂犬病活疫苗和制备狂犬病口服活疫苗的方法 |
| WO2015135558A1 (en) * | 2014-03-12 | 2015-09-17 | Curevac Gmbh | Combination of vaccination and ox40 agonists |
| CA2966191A1 (en) | 2014-11-03 | 2016-05-12 | Merial, Inc. | Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus |
| BR112017016681A2 (pt) * | 2015-02-06 | 2018-04-10 | Heat Biologics Inc | vetor de coexpressão de vacina e moléculas coestimulatórias |
| EP3458474B1 (en) | 2016-05-18 | 2022-07-06 | ModernaTX, Inc. | Combinations of mrnas encoding immune modulating polypeptides and uses thereof |
| US11666649B2 (en) | 2016-10-11 | 2023-06-06 | University Of Miami | Vectors and vaccine cells for immunity against Zika virus |
| CA3058938A1 (en) | 2017-04-04 | 2018-10-11 | Heat Biologics, Inc. | Intratumoral vaccination |
| EA202091958A1 (ru) | 2018-02-23 | 2021-02-04 | Бёрингер Ингельхайм Ветмедика Гмбх | Рекомбинантные вирусные векторные системы, экпрессирующие экзогенные гены кошачьего парамиксовируса, и вакцины, приготовленные из них |
| US12042527B2 (en) | 2019-01-08 | 2024-07-23 | Modernatx, Inc. | Use of mRNAs encoding OX40L, IL-23 and IL-36gamma in combination with immune checkpoint blockade for treating particular cancers |
| CN111518776A (zh) * | 2020-04-16 | 2020-08-11 | 大理大学 | 一种重组狂犬病病毒疫苗株及其制备方法 |
| GB202012331D0 (en) * | 2020-08-07 | 2020-09-23 | Petmedix Ltd | Therapeutic antibodies |
| US11149286B1 (en) | 2020-08-17 | 2021-10-19 | Mayo Foundation For Medical Education And Research | Adenovirus vectors and methods for using adenovirus vectors |
| US20250340659A1 (en) * | 2022-02-09 | 2025-11-06 | PetMedix Ltd. | Therapeutic antibodies |
| CN116656730B (zh) * | 2023-05-25 | 2024-03-19 | 军事科学院军事医学研究院军事兽医研究所 | 一种表达狂犬病病毒g、m蛋白的重组金丝雀痘病毒及其构建方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909462A (en) | 1955-12-08 | 1959-10-20 | Bristol Myers Co | Acrylic acid polymer laxative compositions |
| US5505941A (en) | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
| US4708871A (en) | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| EP0173552B1 (en) | 1984-08-24 | 1991-10-09 | The Upjohn Company | Recombinant dna compounds and the expression of polypeptides such as tpa |
| US6309647B1 (en) * | 1999-07-15 | 2001-10-30 | Aventis Pasteur | Poxvirus—canine dispemper virus (CDV) or measles virus recombinants and compositions and methods employing the recombinants |
| US5756102A (en) | 1990-11-20 | 1998-05-26 | Virogenetics Corporation | Poxvirus-canine distemper virus (CDV) recombinants and compositions and methods employing the recombinants |
| US5843456A (en) | 1991-03-07 | 1998-12-01 | Virogenetics Corporation | Alvac poxvirus-rabies compositions and combination compositions and uses |
| DE69233158T2 (de) * | 1991-03-07 | 2004-05-13 | Connaught Technology Corp., Greenville | Gentechnologisch hergestellter stamm für impfstoffe |
| FR2724385B1 (fr) | 1994-08-29 | 1996-12-13 | Rhone Merieux | Vaccin de la peritonite infectieuse feline. |
| CA2214029A1 (en) | 1995-04-25 | 1996-10-31 | Magda Marquet | Single-vial formulations of dna/lipid complexes |
| US5846946A (en) | 1996-06-14 | 1998-12-08 | Pasteur Merieux Serums Et Vaccins | Compositions and methods for administering Borrelia DNA |
| FR2751227B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives |
| FR2751226B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies du cheval |
| FR2751229B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins |
| FR2751224B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs |
| FR2751225B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique aviaire |
| FR2751228B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Vaccin polynucleotidique bovin pour voie intradermique |
| HUP0004589A3 (en) | 1997-06-30 | 2003-08-28 | Centre Nat Rech Scient | Improved method for transferring nucleic acid into the striped muscle and combination therefor |
| FR2775601B1 (fr) | 1998-03-03 | 2001-09-21 | Merial Sas | Vaccins vivants recombines et adjuves |
| US6497883B1 (en) | 1999-06-10 | 2002-12-24 | Merial | Porcine circovirus recombinant poxvirus vaccine |
| US6541458B1 (en) | 1999-07-16 | 2003-04-01 | Merial | Feline calicivirus genes and vaccines in particular recombinant vaccines |
| US6852705B2 (en) | 2000-01-21 | 2005-02-08 | Merial | DNA vaccines for farm animals, in particular bovines and porcines |
| EP1333863A2 (en) * | 2000-11-03 | 2003-08-13 | Oxford Biomedica (UK) Limited | Vector system for transducing th positive neurons |
| US7740863B2 (en) | 2001-04-06 | 2010-06-22 | Merial | Recombinant vaccine against West Nile Virus |
| CA2570156C (en) | 2004-06-04 | 2014-09-30 | Merial Limited | Needle-free administration of felv vaccines |
| ES2424847T3 (es) | 2004-06-25 | 2013-10-09 | Merial Ltd. | Genes del virus de la fiebre aftosa que expresan avipox recombinantes |
| US8980280B2 (en) | 2005-03-30 | 2015-03-17 | Merial, Inc. | Recombinant feline leukemia virus vaccine containing optimized feline leukemia virus envelope gene |
| PT1881845E (pt) | 2005-04-25 | 2010-05-31 | Merial Ltd | Vacinas de vírus nipah |
| US7384642B2 (en) | 2005-08-25 | 2008-06-10 | Merial Limited | Canine influenza vaccines |
| US7862821B2 (en) | 2006-06-01 | 2011-01-04 | Merial Limited | Recombinant vaccine against bluetongue virus |
| US8008268B2 (en) | 2006-07-25 | 2011-08-30 | Merial Limited | Vaccines against vesicular stomatitis |
| US7910112B2 (en) | 2006-11-06 | 2011-03-22 | Merial Limited | Feline vaccines against avian influenza |
| BRPI0719078A2 (pt) | 2006-11-21 | 2013-12-03 | Merial Ltd | Vacina contra leishmania canina |
| NZ598605A (en) | 2008-10-24 | 2014-04-30 | Merial Ltd | Vaccine against african horse sickness virus |
| CN101884793A (zh) * | 2010-06-29 | 2010-11-17 | 中国人民解放军第三军医大学 | 乙肝病毒核心抗原的免疫增强型基因疫苗及其制备方法 |
| EP3466443B1 (en) | 2012-02-14 | 2020-12-16 | Boehringer Ingelheim Animal Health USA Inc. | Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom |
-
2013
- 2013-02-14 EP EP18208513.4A patent/EP3466443B1/en not_active Not-in-force
- 2013-02-14 WO PCT/US2013/026206 patent/WO2013123242A1/en not_active Ceased
- 2013-02-14 AU AU2013221502A patent/AU2013221502C1/en not_active Ceased
- 2013-02-14 ES ES18208513T patent/ES2866108T3/es active Active
- 2013-02-14 NZ NZ628270A patent/NZ628270A/en not_active IP Right Cessation
- 2013-02-14 BR BR112014020019A patent/BR112014020019A8/pt active Search and Examination
- 2013-02-14 MX MX2014009845A patent/MX360415B/es active IP Right Grant
- 2013-02-14 ES ES13707085T patent/ES2723273T3/es active Active
- 2013-02-14 CA CA2864119A patent/CA2864119C/en active Active
- 2013-02-14 EP EP13707085.0A patent/EP2814506B1/en not_active Not-in-force
- 2013-02-14 NZ NZ722700A patent/NZ722700A/en not_active IP Right Cessation
- 2013-02-14 JP JP2014557782A patent/JP6260972B2/ja not_active Expired - Fee Related
- 2013-02-14 CN CN201380015514.8A patent/CN104203271B/zh not_active Expired - Fee Related
- 2013-02-14 EA EA201400912A patent/EA032389B1/ru not_active IP Right Cessation
- 2013-02-14 US US13/767,603 patent/US9567606B2/en active Active
-
2017
- 2017-01-19 US US15/410,588 patent/US10006050B2/en active Active
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