JP2015509950A5 - - Google Patents
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- Publication number
- JP2015509950A5 JP2015509950A5 JP2014559248A JP2014559248A JP2015509950A5 JP 2015509950 A5 JP2015509950 A5 JP 2015509950A5 JP 2014559248 A JP2014559248 A JP 2014559248A JP 2014559248 A JP2014559248 A JP 2014559248A JP 2015509950 A5 JP2015509950 A5 JP 2015509950A5
- Authority
- JP
- Japan
- Prior art keywords
- oligopeptide
- acylated peptide
- terminal acylated
- peptide
- terminal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 15
- 108010038807 Oligopeptides Proteins 0.000 claims 14
- 102000015636 Oligopeptides Human genes 0.000 claims 14
- 150000001413 amino acids Chemical class 0.000 claims 3
- -1 aromatic amino acid Chemical class 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 150000004665 fatty acids Chemical group 0.000 claims 2
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 239000008203 oral pharmaceutical composition Substances 0.000 claims 2
- 102000004400 Aminopeptidases Human genes 0.000 claims 1
- 108090000915 Aminopeptidases Proteins 0.000 claims 1
- 102000005367 Carboxypeptidases Human genes 0.000 claims 1
- 108010006303 Carboxypeptidases Proteins 0.000 claims 1
- 108090000317 Chymotrypsin Proteins 0.000 claims 1
- 108010067372 Pancreatic elastase Proteins 0.000 claims 1
- 102000016387 Pancreatic elastase Human genes 0.000 claims 1
- 108090000631 Trypsin Proteins 0.000 claims 1
- 102000004142 Trypsin Human genes 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 229960002376 chymotrypsin Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 230000017854 proteolysis Effects 0.000 claims 1
- 230000002797 proteolythic effect Effects 0.000 claims 1
- 239000012588 trypsin Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12157616 | 2012-03-01 | ||
| EP12157616.9 | 2012-03-01 | ||
| US201261625896P | 2012-04-18 | 2012-04-18 | |
| US61/625,896 | 2012-04-18 | ||
| PCT/EP2013/054177 WO2013128003A1 (en) | 2012-03-01 | 2013-03-01 | N-terminally modified oligopeptides and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015509950A JP2015509950A (ja) | 2015-04-02 |
| JP2015509950A5 true JP2015509950A5 (cg-RX-API-DMAC7.html) | 2016-04-21 |
| JP6382111B2 JP6382111B2 (ja) | 2018-08-29 |
Family
ID=49081680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014559248A Expired - Fee Related JP6382111B2 (ja) | 2012-03-01 | 2013-03-01 | Ｎ末端改変オリゴペプチド及びその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20150038435A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2820150A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6382111B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104136626B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013128003A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY36870A (es) * | 2015-08-28 | 2017-03-31 | Hanmi Pharm Ind Co Ltd | Análogos de insulina novedosos |
| SMT202200173T1 (it) | 2016-06-01 | 2022-05-12 | Athira Pharma Inc | Composti |
| KR102698929B1 (ko) | 2016-09-23 | 2024-08-27 | 한미약품 주식회사 | 인슐린 수용체와의 결합력이 감소된, 인슐린 아날로그 및 이의 용도 |
| AU2018214650B2 (en) * | 2017-02-06 | 2022-04-14 | Amolyt Pharma | Compounds, compositions and uses thereof for improvement of bone disorders |
| JP7604098B2 (ja) | 2017-03-23 | 2024-12-23 | ハンミ ファーマシューティカル カンパニー リミテッド | インスリン受容体との結合力が減少されたインスリンアナログの結合体及びその用途 |
| WO2019120639A1 (en) * | 2017-12-21 | 2019-06-27 | Bachem Holding Ag | Solid phase synthesis of acylated peptides |
| WO2019161487A1 (en) * | 2018-02-20 | 2019-08-29 | University Of Manitoba | Food protein-derived peptides as bitter taste blockers |
| US20210196789A1 (en) * | 2018-05-24 | 2021-07-01 | Amolyt Pharma | Heparin-binding domain of igfbp-2 in the treatment of metabolic disorders |
| KR102282558B1 (ko) * | 2018-07-06 | 2021-07-28 | 애니젠 주식회사 | 펩타이드 복합체를 유효성분으로 함유하는 미세먼지 제거 또는 흡착용 화장료 조성물 |
| KR102507392B1 (ko) * | 2020-06-18 | 2023-03-08 | 애니젠 주식회사 | 유기산-올리고펩타이드 복합체를 유효성분으로 포함하는 피부 노화 및 주름 개선용 조성물 |
| CA3194956A1 (en) | 2020-09-11 | 2022-03-17 | Glympse Bio, Inc. | Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment |
| KR20240118914A (ko) | 2021-01-20 | 2024-08-05 | 바이킹 테라퓨틱스 인코포레이티드 | 대사 및 간 질환 치료를 위한 조성물 및 방법 |
| CA3231953A1 (en) | 2021-09-15 | 2023-03-23 | Brian Lian | Compositions and methods for the treatment of metabolic and liver disorders |
| EP4490308A2 (en) * | 2022-03-09 | 2025-01-15 | Sunbird Bio, Inc. | Fluorogenic substrates for aminopeptidase detection in biofluids |
| WO2023196527A2 (en) * | 2022-04-08 | 2023-10-12 | SunVax mRNA Therapeutics Inc. | Ionizable lipid compounds and lipid nanoparticle compositions |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05213990A (ja) * | 1991-02-27 | 1993-08-24 | Taisho Pharmaceut Co Ltd | トリペプチド誘導体 |
| US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| GB9409496D0 (en) * | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
| US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
| AU6059099A (en) * | 1998-09-25 | 2000-04-17 | Children's Medical Center Corporation | Short peptides which selectively modulate the activity of protein kinases |
| FR2864085B1 (fr) * | 2003-12-18 | 2010-09-17 | Centre Nat Rech Scient | Nouveaux modulateurs du proteasome |
| ATE493152T1 (de) * | 2004-09-23 | 2011-01-15 | Guerbet Sa | Liposomale kontrastmittel für die cest-bildgebung |
| CA2597191C (en) * | 2005-02-09 | 2014-04-01 | Helix Biomedix Inc. | Antimicrobial hexapeptides |
| DE102006047529A1 (de) * | 2006-10-07 | 2008-04-10 | Evonik Goldschmidt Gmbh | Oligopeptide enthaltende dermatologische Zusammensetzungen zur Steigerung der Hautempfindlichkeit und der neuronalen Reizwahrnehmung |
| CA2989778C (en) * | 2007-01-19 | 2020-06-30 | Kai Pharmaceuticals, Inc. | Method of modifying peptide compositions |
| WO2008128038A2 (en) * | 2007-04-13 | 2008-10-23 | The Scripps Research Institute | Methods and compositions for treating cardiac dysfunctions |
| JP2011504871A (ja) | 2007-06-01 | 2011-02-17 | ノボ・ノルデイスク・エー／エス | 固体又は半固体担体中にペプチド薬剤を含む自然に分散可能なプレコンセントレイト |
| WO2009030738A1 (en) | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| ES2342754B1 (es) * | 2008-10-03 | 2011-05-11 | Lipotec, S.A. | Peptidos utiles en el tratamiento y/o cuidado de la piel, mucosas, cuero cabelludo y/o cabello y su uso en composiciones cosmeticas o farmaceuticas. |
| JP2012510438A (ja) | 2008-11-28 | 2012-05-10 | ノヴォ・ノルディスク・アー／エス | 誘導体化インスリンペプチドの経口投与に適した医薬組成物 |
| US20130058999A1 (en) | 2010-01-12 | 2013-03-07 | Novo Nordisk A/S | Pharmaceutical compositions for oral administration of insulin peptides |
| WO2012026743A2 (ko) * | 2010-08-23 | 2012-03-01 | 포항공과대학교 산학협력단 | 라벨링제 및 이를 이용한 아미노산 서열 및 단백질 다중 정량 동시 분석방법 |
| CN102219850A (zh) * | 2011-05-03 | 2011-10-19 | 上海格尼生物技术有限公司 | 新的长效glp-1化合物 |
| CN102311483A (zh) * | 2011-07-13 | 2012-01-11 | 大连伊美生物科技有限公司 | 一种低溶血性抗菌脂肽及其制备方法 |
-
2013
- 2013-03-01 CN CN201380011936.8A patent/CN104136626B/zh not_active Expired - Fee Related
- 2013-03-01 JP JP2014559248A patent/JP6382111B2/ja not_active Expired - Fee Related
- 2013-03-01 US US14/380,914 patent/US20150038435A1/en not_active Abandoned
- 2013-03-01 EP EP13707004.1A patent/EP2820150A1/en not_active Withdrawn
- 2013-03-01 WO PCT/EP2013/054177 patent/WO2013128003A1/en not_active Ceased
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