JP2015509716A - 第二世代キメラ抗原受容体におけるｃｄ２シグナル伝達ドメインの使用 - Google Patents

第二世代キメラ抗原受容体におけるｃｄ２シグナル伝達ドメインの使用 Download PDF

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JP2015509716A
JP2015509716A JP2014558875A JP2014558875A JP2015509716A JP 2015509716 A JP2015509716 A JP 2015509716A JP 2014558875 A JP2014558875 A JP 2014558875A JP 2014558875 A JP2014558875 A JP 2014558875A JP 2015509716 A JP2015509716 A JP 2015509716A
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カール エイチ． ジューン
カール エイチ． ジューン
ジョン シェラー
ジョン シェラー
エイブリィ ディー． ポージー
エイブリィ ディー． ポージー
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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JP2014558875A 2012-02-22 2013-02-22 第二世代キメラ抗原受容体におけるｃｄ２シグナル伝達ドメインの使用 Withdrawn JP2015509716A (ja)

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US201261601907P 2012-02-22 2012-02-22
US61/601,907 2012-02-22
PCT/US2013/027361 WO2013126729A1 (en) 2012-02-22 2013-02-22 Use of the cd2 signaling domain in second-generation chimeric antigen receptors

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JP2015509716A true JP2015509716A (ja) 2015-04-02
JP2015509716A5 JP2015509716A5 (OSRAM) 2016-04-07

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US (5) US9783591B2 (OSRAM)
EP (2) EP4275699A3 (OSRAM)
JP (1) JP2015509716A (OSRAM)
KR (1) KR20140127829A (OSRAM)
CN (1) CN104136458A (OSRAM)
AU (1) AU2013222284A1 (OSRAM)
BR (1) BR112014020502A2 (OSRAM)
CA (1) CA2864489C (OSRAM)
EA (1) EA201491573A1 (OSRAM)
ES (1) ES2959443T3 (OSRAM)
IL (1) IL233993A0 (OSRAM)
IN (1) IN2014DN06522A (OSRAM)
MX (1) MX2014010185A (OSRAM)
SG (1) SG11201404284SA (OSRAM)
WO (1) WO2013126729A1 (OSRAM)

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WO2016208754A1 (ja) * 2015-06-24 2016-12-29 学校法人慶應義塾 抗グリピカン－１－免疫抗原受容体
JP2018532432A (ja) * 2015-11-05 2018-11-08 ジュノー セラピューティクス インコーポレイテッド Ｔｒａｆ誘導ドメインを含有するキメラ受容体ならびに関連する組成物および方法
WO2020116606A1 (ja) 2018-12-06 2020-06-11 キリンホールディングス株式会社 Ｔ細胞又はｎｋ細胞の製造方法、ｔ細胞又はｎｋ細胞の培養用培地、ｔ細胞又はｎｋ細胞の培養方法、未分化ｔ細胞の未分化状態を維持する方法及びｔ細胞又はｎｋ細胞の増殖促進剤
WO2020138371A1 (ja) 2018-12-26 2020-07-02 キリンホールディングス株式会社 改変ｔｃｒ及びその製造方法
WO2022255489A1 (ja) 2021-06-04 2022-12-08 キリンホールディングス株式会社 細胞組成物、細胞組成物の製造方法及び細胞組成物を含む医薬組成物
JP2023514232A (ja) * 2020-02-14 2023-04-05 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー Ｃｄ２活性化を伴うキメラ抗原受容体

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US9783591B2 (en) 2012-02-22 2017-10-10 The Trustees Of The University Of Pennsylvania Use of the CD2 signaling domain in second-generation chimeric antigen receptors
ES2949648T3 (es) 2012-12-20 2023-10-02 Purdue Research Foundation Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer
WO2014130635A1 (en) 2013-02-20 2014-08-28 Novartis Ag Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
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US9745368B2 (en) 2013-03-15 2017-08-29 The Trustees Of The University Of Pennsylvania Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
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WO2015090230A1 (en) * 2013-12-19 2015-06-25 Novartis Ag Human mesothelin chimeric antigen receptors and uses thereof
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EP3645036A1 (en) 2017-06-30 2020-05-06 Cellectis Cellular immunotherapy for repetitive administration
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