JP2015508816A - Ｏｘ４０アゴニスト／ｉｌ−２二重癌治療法 - Google Patents
Ｏｘ４０アゴニスト／ｉｌ−２二重癌治療法 Download PDFInfo
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Applications Claiming Priority (1)
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|---|---|---|---|
| PCT/US2012/027496 WO2013130102A2 (en) | 2012-03-02 | 2012-03-02 | Dual ox40 agonist/il-2 cancer therapy methods |
Publications (2)
| Publication Number | Publication Date |
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| JP2015508816A true JP2015508816A (ja) | 2015-03-23 |
| JP2015508816A5 JP2015508816A5 (enExample) | 2015-07-16 |
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| US (1) | US20150157710A1 (enExample) |
| EP (1) | EP2819693A4 (enExample) |
| JP (1) | JP2015508816A (enExample) |
| AU (1) | AU2012371610A1 (enExample) |
| CA (1) | CA2865899A1 (enExample) |
| HK (1) | HK1205691A1 (enExample) |
| WO (1) | WO2013130102A2 (enExample) |
Families Citing this family (19)
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| AU2012369202A1 (en) | 2012-02-06 | 2014-09-25 | Providence Health & Services - Oregon | Cancer treatment and monitoring methods using OX40 agonists |
| ES2754239T3 (es) * | 2014-03-12 | 2020-04-16 | Curevac Ag | Combinación de vacunación y agonistas de OX40 |
| KR20170002410A (ko) | 2014-04-03 | 2017-01-06 | 오거스타 유니버시티 리서치 인스티튜트, 인크. | 종양 유도 면역 반응의 효능을 향상시키는 방법 |
| BR112016027845A2 (pt) * | 2014-05-29 | 2017-10-31 | Medimmune Llc | proteínas de fusão de ox40l e usos das mesmas |
| TW201619200A (zh) * | 2014-10-10 | 2016-06-01 | 麥迪紐有限責任公司 | 人類化抗－ｏｘ４０抗體及其用途 |
| CN107106590B (zh) | 2014-10-24 | 2022-10-18 | 阿斯利康(瑞典)有限公司 | 组合 |
| ES2937020T3 (es) | 2015-03-03 | 2023-03-23 | Kymab Ltd | Anticuerpos, usos y métodos |
| TWI716405B (zh) | 2015-05-07 | 2021-01-21 | 美商艾吉納斯公司 | 抗ox40抗體及其使用方法 |
| US20160347848A1 (en) | 2015-05-28 | 2016-12-01 | Medimmune Limited | Therapeutic combinations and methods for treating neoplasia |
| EP3383430A4 (en) | 2015-12-02 | 2019-12-18 | Agenus Inc. | ANTIBODIES AND METHOD FOR USE THEREOF |
| US11779604B2 (en) | 2016-11-03 | 2023-10-10 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses and methods |
| MA46770A (fr) | 2016-11-09 | 2019-09-18 | Agenus Inc | Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation |
| KR20190105568A (ko) * | 2016-11-10 | 2019-09-17 | 넥타르 테라퓨틱스 | 종양의 면역 요법적 치료 방법 |
| CN109970864A (zh) * | 2017-12-28 | 2019-07-05 | 上海细胞治疗研究院 | 一种双向激活共刺激分子受体及其用途 |
| TW202028222A (zh) | 2018-11-14 | 2020-08-01 | 美商Ionis製藥公司 | Foxp3表現之調節劑 |
| KR20210134686A (ko) | 2019-02-27 | 2021-11-10 | 아이오니스 파마수티컬즈, 인코포레이티드 | Malat1 발현의 조절인자 |
| WO2021064567A1 (en) | 2019-09-30 | 2021-04-08 | Astrazeneca Ab | Combination treatment for cancer |
| CN114437228B (zh) * | 2020-10-30 | 2024-02-06 | 中国科学院生物物理研究所 | 一种il-2与抗体亚单位构成的双功能融合蛋白 |
| CN119896729A (zh) * | 2023-10-26 | 2025-04-29 | 南开大学 | 靶向髓系细胞进而增强ox40激动剂抗体药效的药物组合物的药物组合物及其应用 |
Citations (1)
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| JP2005206563A (ja) * | 2003-12-22 | 2005-08-04 | Hokkaido Technology Licence Office Co Ltd | 標的化ｔ細胞の製造方法及び医薬 |
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| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| DE69133566T2 (de) | 1990-01-12 | 2007-12-06 | Amgen Fremont Inc. | Bildung von xenogenen Antikörpern |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| US20030035790A1 (en) * | 1999-01-15 | 2003-02-20 | Shu-Hsia Chen | Combination therapy for the prevention or treatment of cancer, inflammatory disorders or infectious diseases in a subject |
| US20030040477A1 (en) * | 2002-09-23 | 2003-02-27 | Anthony Montgomery | Methods and compositions for modulating t cell activation and uses thereof |
| US20110008368A1 (en) * | 2006-01-13 | 2011-01-13 | Board Of Regents, The University Of Texas System | Methods of modulating the ox40 receptor to treat cancer |
| GB0620894D0 (en) * | 2006-10-20 | 2006-11-29 | Univ Southampton | Human immune therapies using a CD27 agonist alone or in combination with other immune modulators |
| US8629098B2 (en) * | 2008-01-15 | 2014-01-14 | Yale University | Compositions and methods for adoptive and active immunotherapy |
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- 2012-03-02 JP JP2014559875A patent/JP2015508816A/ja active Pending
- 2012-03-02 CA CA2865899A patent/CA2865899A1/en not_active Abandoned
- 2012-03-02 EP EP12869998.0A patent/EP2819693A4/en not_active Withdrawn
- 2012-03-02 WO PCT/US2012/027496 patent/WO2013130102A2/en not_active Ceased
- 2012-03-02 HK HK15106316.7A patent/HK1205691A1/xx unknown
- 2012-03-02 AU AU2012371610A patent/AU2012371610A1/en not_active Abandoned
- 2012-03-02 US US14/381,785 patent/US20150157710A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005206563A (ja) * | 2003-12-22 | 2005-08-04 | Hokkaido Technology Licence Office Co Ltd | 標的化ｔ細胞の製造方法及び医薬 |
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| JPN6015052223; Ｅｕｒ．Ｊ．Ｉｍｍｕｎｏｌ． ３４, 2004, ｐ．７５２-７６１ * |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2013130102A3 (en) | 2014-04-17 |
| EP2819693A2 (en) | 2015-01-07 |
| AU2012371610A1 (en) | 2014-10-02 |
| EP2819693A4 (en) | 2015-10-28 |
| WO2013130102A2 (en) | 2013-09-06 |
| HK1205691A1 (en) | 2015-12-24 |
| CA2865899A1 (en) | 2013-09-06 |
| US20150157710A1 (en) | 2015-06-11 |
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