JP2015508757A5 - - Google Patents

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Publication number
JP2015508757A5
JP2015508757A5 JP2014556052A JP2014556052A JP2015508757A5 JP 2015508757 A5 JP2015508757 A5 JP 2015508757A5 JP 2014556052 A JP2014556052 A JP 2014556052A JP 2014556052 A JP2014556052 A JP 2014556052A JP 2015508757 A5 JP2015508757 A5 JP 2015508757A5
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JP
Japan
Prior art keywords
seq
antibody
variable region
heavy chain
light chain
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JP2014556052A
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English (en)
Japanese (ja)
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JP2015508757A (ja
JP6405242B2 (ja
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Priority claimed from PCT/EP2013/052439 external-priority patent/WO2013117647A1/en
Publication of JP2015508757A publication Critical patent/JP2015508757A/ja
Publication of JP2015508757A5 publication Critical patent/JP2015508757A5/ja
Application granted granted Critical
Publication of JP6405242B2 publication Critical patent/JP6405242B2/ja
Active legal-status Critical Current
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JP2014556052A 2012-02-07 2013-02-07 Mica結合剤 Active JP6405242B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261595902P 2012-02-07 2012-02-07
US61/595,902 2012-02-07
US201261625841P 2012-04-18 2012-04-18
US61/625,841 2012-04-18
PCT/EP2013/052439 WO2013117647A1 (en) 2012-02-07 2013-02-07 Mica binding agents

Publications (3)

Publication Number Publication Date
JP2015508757A JP2015508757A (ja) 2015-03-23
JP2015508757A5 true JP2015508757A5 (https=) 2016-03-31
JP6405242B2 JP6405242B2 (ja) 2018-10-17

Family

ID=47714068

Family Applications (1)

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JP2014556052A Active JP6405242B2 (ja) 2012-02-07 2013-02-07 Mica結合剤

Country Status (11)

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US (2) US10577416B2 (https=)
EP (1) EP2812027A1 (https=)
JP (1) JP6405242B2 (https=)
CN (1) CN104244977A (https=)
AU (1) AU2013218017B2 (https=)
BR (1) BR112014019611A2 (https=)
CA (1) CA2862101A1 (https=)
IL (1) IL233793B (https=)
RU (1) RU2656183C2 (https=)
SG (1) SG11201404177PA (https=)
WO (1) WO2013117647A1 (https=)

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WO2020035345A1 (en) 2018-08-14 2020-02-20 Innate Pharma Treatment of colorectal cancer by a combination of an anti-mica antibody and an anti-nkg2a antibody
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CA3160759A1 (en) * 2019-12-05 2021-06-10 Vycellix, Inc. Modulators of the immune escape mechanism for universal cell therapy
CN111471099B (zh) * 2020-03-31 2022-04-12 长沙学院 MICA胞外区突变体及其筛选的方法、scFv-MICA融合抗体及其制备方法和应用
CN111718416B (zh) * 2020-06-25 2022-04-01 菲鹏生物股份有限公司 抗硫氧还蛋白的抗体、其应用和诊断试剂盒
CA3184940A1 (en) 2020-07-07 2022-01-13 Jennifer Donglan WU Mic antibodies and binding agents and methods of using the same
CN116547301A (zh) 2020-08-10 2023-08-04 先天制药公司 使用抗体进行的细胞表面mica和micb检测
CN112694532B (zh) * 2021-01-12 2023-04-18 倍而达药业(苏州)有限公司 抗Siglec-15的抗体或其抗原结合片段及应用
CN113502265B (zh) * 2021-05-25 2024-05-28 昭泰英基生物医药(香港)有限公司 将t细胞重编程为类nk细胞的诱导剂及其应用
CN118307672B (zh) * 2021-07-14 2026-04-17 浙江大学 一种抗人MICA/B α3区的抗体及其应用
CN114369162B (zh) * 2021-12-28 2023-05-30 合肥天港免疫药物有限公司 抗体及其应用
CN114369161B (zh) * 2021-12-28 2023-06-23 合肥天港免疫药物有限公司 Mica抗体及其应用
CN118027195B (zh) * 2023-05-06 2025-07-04 合肥天港免疫药物有限公司 亲和力成熟的mica抗体及其应用

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