|
US7153684B1
(en)
|
1992-10-08 |
2006-12-26 |
Vanderbilt University |
Pluripotential embryonic stem cells and methods of making same
|
|
US5753225A
(en)
|
1993-12-03 |
1998-05-19 |
The Regents Of The University Of California |
Antibodies that mimic actions of neurotrophins
|
|
US6719972B1
(en)
|
1994-06-03 |
2004-04-13 |
Repligen Corporation |
Methods of inhibiting T cell proliferation or IL-2 accumulation with CTLA4- specific antibodies
|
|
US5843780A
(en)
|
1995-01-20 |
1998-12-01 |
Wisconsin Alumni Research Foundation |
Primate embryonic stem cells
|
|
AU729377B2
(en)
|
1997-10-23 |
2001-02-01 |
Asterias Biotherapeutics, Inc. |
Methods and materials for the growth of primate-derived primordial stem cells in feeder-free culture
|
|
US7410798B2
(en)
|
2001-01-10 |
2008-08-12 |
Geron Corporation |
Culture system for rapid expansion of human embryonic stem cells
|
|
US6667176B1
(en)
|
2000-01-11 |
2003-12-23 |
Geron Corporation |
cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
|
|
US7109003B2
(en)
|
1998-12-23 |
2006-09-19 |
Abgenix, Inc. |
Methods for expressing and recovering human monoclonal antibodies to CTLA-4
|
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
EP1261376A1
(en)
|
2000-01-27 |
2002-12-04 |
Genetics Institute, LLC |
Antibodies against ctla4(cd152), conjugates comprising same, and uses thereof
|
|
US7427665B2
(en)
|
2000-12-08 |
2008-09-23 |
Alexion Pharmaceuticals, Inc. |
Chronic lymphocytic leukemia cell line
|
|
WO2003042402A2
(en)
|
2001-11-13 |
2003-05-22 |
Dana-Farber Cancer Institute, Inc. |
Agents that modulate immune cell activation and methods of use thereof
|
|
BR0309254A
(pt)
|
2002-04-12 |
2005-03-01 |
Medarex Inc |
Uso de um anticorpo anti-ctla-4
|
|
ES2350687T3
(es)
|
2002-07-03 |
2011-01-26 |
Ono Pharmaceutical Co., Ltd. |
Composiciones de inmunopotenciación.
|
|
CN1753912B
(zh)
|
2002-12-23 |
2011-11-02 |
惠氏公司 |
抗pd-1抗体及其用途
|
|
US20060275288A1
(en)
*
|
2005-01-20 |
2006-12-07 |
Grihalde Nelson D |
GLP-1 receptor agonist and allosteric modulator monoclonal antibodies and uses thereof
|
|
CA2599606A1
(en)
*
|
2005-02-23 |
2006-08-31 |
Merrimack Pharmaceuticals, Inc. |
Bispecific binding agents for modulating biological activity
|
|
RU2494107C2
(ru)
|
2005-05-09 |
2013-09-27 |
Оно Фармасьютикал Ко., Лтд. |
Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами
|
|
WO2006133164A2
(en)
|
2005-06-06 |
2006-12-14 |
Wyeth |
Anti-trkb monoclonal antibodies and uses thereof
|
|
CN104356236B
(zh)
|
2005-07-01 |
2020-07-03 |
E.R.施贵宝&圣斯有限责任公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
|
US8278104B2
(en)
|
2005-12-13 |
2012-10-02 |
Kyoto University |
Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
|
|
US20090227032A1
(en)
|
2005-12-13 |
2009-09-10 |
Kyoto University |
Nuclear reprogramming factor and induced pluripotent stem cells
|
|
BRPI0619794B8
(pt)
|
2005-12-13 |
2022-06-14 |
Univ Kyoto |
Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas
|
|
US8841255B2
(en)
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
|
US20100267145A1
(en)
|
2006-06-05 |
2010-10-21 |
Hiroshima University |
Immunocompetent cell having anti-cd38 antibody on its cell surface
|
|
US8501693B2
(en)
|
2006-08-04 |
2013-08-06 |
Amylin Pharmaceuticals, Llc |
Use of exendins and exendin agonists and GLP-1 receptor agonists for altering the concentration of fibrinogen
|
|
EP2126054B1
(en)
*
|
2007-01-31 |
2016-07-06 |
Yeda Research And Development Company Limited |
Redirected, genetically-engineered t regulatory cells and their use in suppression of autoimmune and inflammatory disease
|
|
US10155038B2
(en)
*
|
2007-02-02 |
2018-12-18 |
Yale University |
Cells prepared by transient transfection and methods of use thereof
|
|
JP2008307007A
(ja)
|
2007-06-15 |
2008-12-25 |
Bayer Schering Pharma Ag |
出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
|
|
US9683232B2
(en)
|
2007-12-10 |
2017-06-20 |
Kyoto University |
Efficient method for nuclear reprogramming
|
|
CA2712298C
(en)
*
|
2008-01-17 |
2015-11-24 |
Irm Llc |
Improved anti-trkb antibodies
|
|
JP5794917B2
(ja)
|
2008-09-12 |
2015-10-14 |
アイシス・イノベーション・リミテッドIsis Innovationlimited |
Pd−1特異抗体およびその使用
|
|
KR101050829B1
(ko)
|
2008-10-02 |
2011-07-20 |
서울대학교산학협력단 |
항 pd-1 항체 또는 항 pd-l1 항체를 포함하는 항암제
|
|
US20100261776A1
(en)
*
|
2008-11-07 |
2010-10-14 |
The Research Foundation Of State University Of New York |
Bruton's tyrosine kinase as anti-cancer drug target
|
|
US20120148586A1
(en)
*
|
2009-08-27 |
2012-06-14 |
Joyce Ching Tsu Chou |
Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders
|
|
US9273283B2
(en)
|
2009-10-29 |
2016-03-01 |
The Trustees Of Dartmouth College |
Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
|
|
US20120263722A1
(en)
*
|
2010-11-04 |
2012-10-18 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
|
US8771696B2
(en)
|
2010-11-23 |
2014-07-08 |
Regeneron Pharmaceuticals, Inc. |
Method of reducing the severity of stress hyperglycemia with human antibodies to the glucagon receptor
|
|
GB2491106A
(en)
|
2011-05-18 |
2012-11-28 |
Univ Basel |
Antibodies against tropomyosin-related kinase B receptors
|
|
ES3063961T3
(en)
*
|
2014-02-14 |
2026-04-21 |
Cellectis |
Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells
|
|
EP3593812A3
(en)
*
|
2014-03-15 |
2020-05-27 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor
|
|
TWI750110B
(zh)
*
|
2014-07-21 |
2021-12-21 |
瑞士商諾華公司 |
使用人類化抗-bcma嵌合抗原受體治療癌症
|
|
CA3197849A1
(en)
*
|
2014-12-29 |
2016-07-07 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
US20170151281A1
(en)
*
|
2015-02-19 |
2017-06-01 |
Batu Biologics, Inc. |
Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
|
|
CN110699371A
(zh)
*
|
2016-03-18 |
2020-01-17 |
江苏普瑞康生物医药科技有限公司 |
一种基于FcγRⅢa的嵌合基因及其用途
|
|
CN109415698A
(zh)
*
|
2016-06-16 |
2019-03-01 |
斯隆-凯特林纪念癌症中心 |
工程化Treg细胞
|