JP2015504048A5 - - Google Patents

Download PDF

Info

Publication number
JP2015504048A5
JP2015504048A5 JP2014548945A JP2014548945A JP2015504048A5 JP 2015504048 A5 JP2015504048 A5 JP 2015504048A5 JP 2014548945 A JP2014548945 A JP 2014548945A JP 2014548945 A JP2014548945 A JP 2014548945A JP 2015504048 A5 JP2015504048 A5 JP 2015504048A5
Authority
JP
Japan
Prior art keywords
heterocyclyl
arylalkyl
heteroaryl
alkynyl
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014548945A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015504048A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/071223 external-priority patent/WO2013096755A1/en
Publication of JP2015504048A publication Critical patent/JP2015504048A/ja
Publication of JP2015504048A5 publication Critical patent/JP2015504048A5/ja
Pending legal-status Critical Current

Links

JP2014548945A 2011-12-21 2012-12-21 タンパク質分解抵抗性水素結合サロゲートヘリックス Pending JP2015504048A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161578652P 2011-12-21 2011-12-21
US201161578646P 2011-12-21 2011-12-21
US61/578,652 2011-12-21
US61/578,646 2011-12-21
PCT/US2012/071223 WO2013096755A1 (en) 2011-12-21 2012-12-21 Proteolytically resistant hydrogen bond surrogate helices

Publications (2)

Publication Number Publication Date
JP2015504048A JP2015504048A (ja) 2015-02-05
JP2015504048A5 true JP2015504048A5 (enExample) 2016-02-18

Family

ID=48669532

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014548945A Pending JP2015504048A (ja) 2011-12-21 2012-12-21 タンパク質分解抵抗性水素結合サロゲートヘリックス

Country Status (6)

Country Link
US (1) US9376469B2 (enExample)
EP (1) EP2793920A4 (enExample)
JP (1) JP2015504048A (enExample)
CN (1) CN104066435A (enExample)
CA (1) CA2895930A1 (enExample)
WO (1) WO2013096755A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014CN02398A (enExample) * 2011-08-31 2015-06-19 Univ New York
EP2964245A4 (en) * 2013-01-19 2016-09-21 Univ New York HYDROGENIC SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR THE REACTIVATION OF P53
US20150065436A1 (en) * 2013-09-03 2015-03-05 University Of Southern California INHIBITING INTERACTION BETWEEN HIF-1ALPHA AND p300/CBP WITH HYDROGEN BOND SURROGATE-BASED HELICES
EP3107929A4 (en) * 2014-02-22 2017-07-19 New York University Alpha3beta hydrogen bond surrogate macrocycles as modulators of ras
SG11201608303QA (en) * 2014-04-04 2016-11-29 Del Mar Pharmaceuticals Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer
CN108024987A (zh) * 2014-10-10 2018-05-11 德玛医药 用于治疗癌症的二去水卫矛醇的类似物或衍生物与含铂抗肿瘤药物的组合
EP3672995A1 (en) * 2017-08-23 2020-07-01 Cyca Oncosolutions Limited Cell membrane penetrating conjugates
JP7561364B2 (ja) * 2020-04-30 2024-10-04 国立大学法人東北大学 蛍光偏光免疫分析法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005118620A2 (en) 2004-05-27 2005-12-15 New York University Methods for preparing internally constraied peptides and peptidomimetics
JP5631201B2 (ja) 2007-03-28 2014-11-26 プレジデント アンド フェローズ オブ ハーバード カレッジ ステッチングされたポリペプチド
ES2446249T3 (es) 2008-09-18 2014-03-06 New York University Inhibición de la interación entre hif-1a y p300/cbp con hélices basadas en sustitutos de los enlaces de hidrógeno
US20120178700A1 (en) * 2008-09-22 2012-07-12 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
US8835602B2 (en) * 2009-03-06 2014-09-16 Indian Institute Of Science Templates for nucleation and propagation of peptide secondary structure
US8333988B2 (en) * 2009-09-03 2012-12-18 Gradalis, Inc. Targeted delivery using tissue-specific peptidomimetic ligands
ES2586411T3 (es) * 2011-03-04 2016-10-14 New York University Macrociclos sustitutos de enlace de hidrógeno como moduladores de Ras
IN2014CN02398A (enExample) 2011-08-31 2015-06-19 Univ New York

Similar Documents

Publication Publication Date Title
JP2015504048A5 (enExample)
Qian et al. Targeting intracellular protein–protein interactions with cell-permeable cyclic peptides
ES2700999T3 (es) Modificación de polipéptidos
JP2015518831A5 (enExample)
JP2009521908A5 (enExample)
JP2009529509A5 (enExample)
JP2016065060A5 (enExample)
JP2016512213A5 (enExample)
EP2476697A3 (en) Peptide vaccines for cancers expressing MPHOSPH1 or DEPDC1 polypeptides
EA021222B8 (ru) Биологически активные белки, имеющие повышенную стабильность in vivo и/или in vitro
JP2013518055A5 (enExample)
JP2016199546A5 (enExample)
JP2008519589A5 (enExample)
JP2014231516A5 (enExample)
RU2016146198A (ru) Терапевтические dll4-связывающие белки
JP2013504589A5 (enExample)
JP2013500990A5 (enExample)
RU2013101972A (ru) Антигенные композиции респираторного синцитиального вируса и способы
JP2008509928A5 (enExample)
JP2014526881A5 (enExample)
WO2006090810A3 (en) Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides
JP2009533317A5 (enExample)
JP2014524477A5 (enExample)
JP5559531B2 (ja) がんまたは炎症を治療するための表面ヌクレオリンの多価合成リガンドの使用
EP2481748A3 (en) Foxp3 peptide vaccine